About
Copy Link
Titles
Associate Research Scientist
Appointments
Neurosurgery
Associate Research ScientistPrimary
Other Departments & Organizations
Research
Copy Link
Research at a Glance
Publications Timeline
A big-picture view of Zhouqi Meng's research output by year.
22Publications
1,425Citations
Publications
2022
Fast Fourier Transform-weighted Photoacoustic Imaging by In Vivo Magnetic Alignment of Hybrid Nanorods
Li Z, Meng Z, Tian F, Ye Z, Zhou X, Zhong X, Chen Q, Yang M, Liu Z, Yin Y. Fast Fourier Transform-weighted Photoacoustic Imaging by In Vivo Magnetic Alignment of Hybrid Nanorods. Nano Letters 2022, 22: 5158-5166. PMID: 35762802, DOI: 10.1021/acs.nanolett.2c00854.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsMagnetic alignmentPhoton-phonon conversionMagnetic fieldField directionPA signalHybrid nanorodsPA imaging techniqueFast Fourier transformHigh-resolution tomographyPA imagingPeriodic changesImage qualityImaging sensitivityActivity modulationComputational algorithmBackground noisePixel subtractionFourier transformFrequency domainPhotoacousticsNanovaccines with cell-derived components for cancer immunotherapy
Meng Z, Zhang Y, Zhou X, Ji J, Liu Z. Nanovaccines with cell-derived components for cancer immunotherapy. Advanced Drug Delivery Reviews 2022, 182: 114107. PMID: 34995678, DOI: 10.1016/j.addr.2021.114107.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCancer nanovaccinesCancer immunotherapyCell-derived componentsBiomimetic nanovaccinesTumor-specific immunological responsesTumor-associated antigensAntitumor immunityCell-derived nanovesiclesImmunotherapeutic approachesAttack tumorsImmunotherapy responseVaccine platformNanovaccineImmune responseImmunological responseClinical translationCancerImmunotherapyCell membraneReview articleCell lysatesCellsTumorExogenous materialsAntigen
2021
Ultra-small natural product based coordination polymer nanodots for acute kidney injury relief
Zhang R, Cheng L, Dong Z, Hou L, Zhang S, Meng Z, Betzer O, Wang Y, Popovtzer R, Liu Z. Ultra-small natural product based coordination polymer nanodots for acute kidney injury relief. Materials Horizons 2021, 8: 1314-1322. PMID: 34821924, DOI: 10.1039/d0mh00193g.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsUltrasound-Mediated Remotely Controlled Nanovaccine Delivery for Tumor Vaccination and Individualized Cancer Immunotherapy
Meng Z, Zhang Y, She J, Zhou X, Xu J, Han X, Wang C, Zhu M, Liu Z. Ultrasound-Mediated Remotely Controlled Nanovaccine Delivery for Tumor Vaccination and Individualized Cancer Immunotherapy. Nano Letters 2021, 21: 1228-1237. PMID: 33522825, DOI: 10.1021/acs.nanolett.0c03646.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsIndividualized cancer immunotherapyCancer immunotherapySubcutaneous injectionPostoperative tumor metastasisImmune checkpoint blockadeAntitumor immune responseOptimal vaccine effectivenessDelivery of vaccinesCheckpoint blockadeInjection of vaccineTumor vaccinesTumor metastasisImmune responsePatient comfortVaccine effectivenessNanovaccineResponse to ultrasound treatmentImmunotherapyVaccine releaseVaccineBurst releaseTumorUltrasound-mediatedDiseaseTreatment
2020
Thermo‐Triggered In Situ Chitosan‐Based Gelation System for Repeated and Enhanced Sonodynamic Therapy Post a Single Injection
She J, Zhou X, Zhang Y, Zhang R, Li Q, Zhu W, Meng Z, Liu Z. Thermo‐Triggered In Situ Chitosan‐Based Gelation System for Repeated and Enhanced Sonodynamic Therapy Post a Single Injection. Advanced Healthcare Materials 2020, 10: e2001208. PMID: 33236504, DOI: 10.1002/adhm.202001208.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsEfficacy of sonodynamic therapySonodynamic therapySolid tumorsReactive oxygen speciesDecomposition of endogenous H2 O2Single dose injectionOptimal therapeutic responseDeep-seated tumorsTherapeutic responseRobust treatment effectsDose injectionGeneration of reactive oxygen speciesPatient incomplianceTumorSide effectsEndogenous H2 O2Near-Infrared Light-Responsive Nitric Oxide Delivery Platform for Enhanced Radioimmunotherapy
Zhou X, Meng Z, She J, Zhang Y, Yi X, Zhou H, Zhong J, Dong Z, Han X, Chen M, Fan Q, Yang K, Wang C. Near-Infrared Light-Responsive Nitric Oxide Delivery Platform for Enhanced Radioimmunotherapy. Nano-Micro Letters 2020, 12: 100. PMID: 34138094, PMCID: PMC7770715, DOI: 10.1007/s40820-020-00431-3.Peer-Reviewed Original ResearchCitationsAltmetricConceptsImmune checkpoint blockade therapyAnti-PD-L1Checkpoint blockade therapyImmunosuppressive tumor microenvironmentDelivery platformBlockade therapyNO delivery systemsRadiotherapy effectTumor microenvironmentTumor growthNO delivery platformDelivery systemRadiotherapyRadioimmunotherapyTumorTherapyMicroenvironment
2019
Renal Clearable Ru-based Coordination Polymer Nanodots for Photoacoustic Imaging Guided Cancer Therapy
Zhang R, Fan X, Meng Z, Lin H, Jin Q, Gong F, Dong Z, Li Y, Chen Q, Liu Z, Cheng L. Renal Clearable Ru-based Coordination Polymer Nanodots for Photoacoustic Imaging Guided Cancer Therapy. Theranostics 2019, 9: 8266-8276. PMID: 31754395, PMCID: PMC6857064, DOI: 10.7150/thno.36986.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsLong-term toxicityImaging-guided photothermal therapyPolymer nanodotsConversion efficiencyRenal excretionCancer therapyPhotothermal conversion efficiencyPhotothermal therapyImaging-guided cancer therapyRuthenium ionsImaging guided cancer therapyCancer treatment efficiencyChronic retentionRenal clearanceTumor retentionSystemic administrationEfficient tumor retentionTherapyEfficient renal clearanceHigh photothermal conversion efficiencyPhotothermal conversionClinical applicationTheranostic nanoagentsPhotothermal agentsNanodotsUltrasound-Responsive Conversion of Microbubbles to Nanoparticles to Enable Background-Free in Vivo Photoacoustic Imaging
Meng Z, Zhou X, She J, Zhang Y, Feng L, Liu Z. Ultrasound-Responsive Conversion of Microbubbles to Nanoparticles to Enable Background-Free in Vivo Photoacoustic Imaging. Nano Letters 2019, 19: 8109-8117. PMID: 31597418, DOI: 10.1021/acs.nanolett.9b03331.Peer-Reviewed Original ResearchCitationsConceptsOptical absorbancePA signalBackground-freeRed-shifted surface plasmon resonanceAu NPsBackground PA signalsPA imagingUS pulsesInterfere with signalingTissue background signalSpatial resolutionIn vivo PA imagingNanoscale aggregatesBackground signalDetection of targetsSurface plasmon resonanceImaging sensitivityLipid shellShell of microbubblesPlasmon resonancePA imaging probeGold nanoparticlesIn vivoPhotoacousticsIn vivo experimentsLight‐Triggered In Situ Gelation to Enable Robust Photodynamic‐Immunotherapy by Repeated Stimulations
Meng Z, Zhou X, Xu J, Han X, Dong Z, Wang H, Zhang Y, She J, Xu L, Wang C, Liu Z. Light‐Triggered In Situ Gelation to Enable Robust Photodynamic‐Immunotherapy by Repeated Stimulations. Advanced Materials 2019, 31: e1900927. PMID: 31012164, DOI: 10.1002/adma.201900927.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsAntitumor immune responseImmune responsePhotodynamic therapyGrowth of distant tumorsLong-term tumor retentionSystemic antitumor immune responseSingle-dose injectionConventional photodynamic therapyHypoxic tumor microenvironmentTumor hypoxia reliefAdjuvant nanoparticlesCheckpoint blockadeAbscopal effectDistant tumorsRechallenged tumorsMetastatic tumorsPhotodynamic therapy efficacyTumor microenvironmentTumor retentionLocal injectionRepeated stimulationTumorHypoxia reliefIn situ gelationStimulation
2018
Near-Infrared-Triggered in Situ Gelation System for Repeatedly Enhanced Photothermal Brachytherapy with a Single Dose
Meng Z, Chao Y, Zhou X, Liang C, Liu J, Zhang R, Cheng L, Yang K, Pan W, Zhu M, Liu Z. Near-Infrared-Triggered in Situ Gelation System for Repeatedly Enhanced Photothermal Brachytherapy with a Single Dose. ACS Nano 2018, 12: 9412-9422. PMID: 30148960, DOI: 10.1021/acsnano.8b04544.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsEfficacy of brachytherapyIrradiation of tumorsSolid tumorsBrachytherapySingle doseTumor cellsTumor hypoxiaLocal injectionNear tumorsNIR irradiationTumorTumor temperatureCancer treatmentHypoxic regionsClinical settingRadiotherapeutic agentsDistribution of radioactivityHydrogel systemNon-optimal distributionHybrid hydrogel systemIn situ gelationThermal initiationAIPHLong-termCancer
Get In Touch
Copy Link
Contacts
Email