Xiaoyu Huang

2024

• Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts.

  Lin X, Gupta D, Vaitsiankova A, Bhandari SK, Leung KSK, Menolfi D, Lee BJ, Russell HR, Gershik S, Huang X, Gu W, McKinnon PJ, Dantzer F, Rothenberg E, Tomkinson AE, Zha S. Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts. Mol Cell 2024, 84: 3916-3931.e7. PMID: 39383878, DOI: 10.1016/j.molcel.2024.09.020.

  Peer-Reviewed Original Research In Press

• XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites.

  Lin X, Leung KSK, Wolfe KF, Lee BJ, Zha S. XRCC1 mediates PARP1- and PAR-dependent recruitment of PARP2 to DNA damage sites. BioRxiv 2024 PMID: 38798615, DOI: 10.1101/2024.05.14.594230.

  Peer-Reviewed Original Research In Press