Qing Liu
Research Associate Internal Medicine PulmonaryCards
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Research Associate Internal Medicine Pulmonary
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Qing Liu's published research.
Publications Timeline
A big-picture view of Qing Liu's research output by year.
Adam V Wisnewski, PhD, D(ABMLI)
Carrie A Redlich, MD, MPH, BA
Jian Liu
20Publications
841Citations
Publications
2008
Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates
Wisnewski AV, Liu Q, Liu J, Redlich CA. Human innate immune responses to hexamethylene diisocyanate (HDI) and HDI–albumin conjugates. Clinical & Experimental Allergy 2008, 38: 957-967. PMID: 18498542, PMCID: PMC3131007, DOI: 10.1111/j.1365-2222.2008.02982.x.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdipokinesAdministration, InhalationAlbuminsAntigens, CDBlotting, WesternCells, CulturedChemokine CCL2Chitinase-3-Like Protein 1ChitinasesCyanatesEnzyme-Linked Immunosorbent AssayGene ExpressionGlycoproteinsHumansImmunity, InnateIntramolecular OxidoreductasesIsocyanatesLectinsLeukocytes, MononuclearLysosomesMacrophage Migration-Inhibitory FactorsMicroscopy, FluorescenceOligonucleotide Array Sequence AnalysisPolymerase Chain ReactionPolymorphism, GeneticProteinsRNAConceptsPeripheral blood mononuclear cellsInnate immune responseImmune responsePercentage of PBMCHuman peripheral blood mononuclear cellsFlow cytometrySystemic innate immune responseExposure-dependent decreaseMonocyte/macrophage traffickingHuman innate immune responseProtein expressionSpecific inhalation challengeBlood mononuclear cellsAdaptive immune responsesLow-density lipoproteinPattern recognition receptorsInhalation challengeOccupational asthmaClinical spectrumControl antigenMononuclear cellsHDI exposureSerum concentrationsAdaptive immunityGene/protein expression
2005
Glutathione protects human airway proteins and epithelial cells from isocyanates
Wisnewski AV, Liu Q, Liu J, Redlich CA. Glutathione protects human airway proteins and epithelial cells from isocyanates. Clinical & Experimental Allergy 2005, 35: 352-357. PMID: 15784115, DOI: 10.1111/j.1365-2222.2005.02185.x.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDose-dependent mannerAirway fluidGSH levelsHuman airway epithelial cellsVapor exposure systemEpithelial cellsHuman airway epithelial cell lineAirway epithelial cell lineEpithelial lining fluidAirway epithelial cellsEpithelial cell exposureEpithelial cell toxicityAllergic sensitizationEpithelial cell lineHDI exposureAirway proteinsLining fluidAirway cellsIsocyanate exposureVivo exposureOccupational limitsNCI-H292Physiologic levelsEpithelial fluidToxicity studies
2004
Isocyanate vapor-induced antigenicity of human albumin
Wisnewski AV, Stowe MH, Cartier A, Liu Q, Liu J, Chen L, Redlich CA. Isocyanate vapor-induced antigenicity of human albumin. Journal Of Allergy And Clinical Immunology 2004, 113: 1178-1184. PMID: 15208602, DOI: 10.1016/j.jaci.2004.03.009.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHDI exposureHuman albuminAuto body shop workersHDI vaporHuman immune systemOccupational asthmaHumoral armSpecific IgEIgG titersHealthy workersImmune responseSerology studiesHuman airwaysImmune systemSignificant associationAntigenic formsShop workersAlbumin conjugatesAsthmaticsAsthmaIgEAntigenicityParallel studyAlbuminSignificant changes
2003
Human γ/δ T-cell proliferation and IFN-γ production induced by hexamethylene diisocyanate
Wisnewski AV, Herrick CA, Liu Q, Chen L, Bottomly K, Redlich CA. Human γ/δ T-cell proliferation and IFN-γ production induced by hexamethylene diisocyanate. Journal Of Allergy And Clinical Immunology 2003, 112: 538-546. PMID: 13679813, DOI: 10.1016/s0091-6749(03)01865-7.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsGamma/delta T cellsDelta T cellsHuman immune responseT cellsT cell receptorImmune responseAlpha/beta T cell receptorBeta T cell receptorHuman airway epithelial cellsIFN-γ productionGamma/deltaT cell proliferationAirway epithelial cellsHuman T cell lineT cell linesHuman T cellsCell typesOccupational asthmaCytokine productionPeripheral bloodIL-13IL-5Antigen-mediated selectionAntigen leadIFN-gammaSequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations
Safitri I, Jalloh A, Tantular I, Pusarawati S, Win T, Liu Q, Ferreira M, Dachlan Y, Horii T, Kawamoto F. Sequence diversity in the amino-terminal region of the malaria-vaccine candidate serine repeat antigen in natural Plasmodium falciparum populations. Parasitology International 2003, 52: 117-131. PMID: 12798923, DOI: 10.1016/s1383-5769(02)00088-0.Peer-Reviewed Original ResearchCitationsRecent developments in diisocyanate asthma
Liu Q, Wisnewski AV. Recent developments in diisocyanate asthma. Annals Of Allergy Asthma & Immunology 2003, 90: 35-41. PMID: 12772950, DOI: 10.1016/s1081-1206(10)61647-x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsDiisocyanate asthmaPotential long-term adverse effectsMajor histocompatibility complex class II allelesLong-term adverse effectsGlutathione S-transferase polymorphismsImmune-dependent mechanismsAntigen-independent mechanismsLong-term followGenetic factorsHuman immune responseClass II allelesEffective diagnostic testAllergic asthmaAsthma patientsAtopic asthmaDiisocyanate exposureSymptomatic patientsImmune basisSensitized patientsAsthma pathogenesisPrognostic valueImmunologic differencesAirway epitheliumImmune responseAsthma
2002
Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies.
Wisnewski AV, Liu Q, Miller JJ, Magoski N, Redlich CA. Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies. Environmental Health Perspectives 2002, 110: 901-907. PMID: 12204825, PMCID: PMC1240990, DOI: 10.1289/ehp.02110901.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHuman airway epithelial cellsImmunofluorescence analysisAirway epithelial cellsEpithelial cellsThiol redox homeostasisThioredoxin reductase expressionCellular stressEpithelial cell lineSensitive genesMicroarray analysisNorthern analysisHexamethylene diisocyanate exposureGenesAirway epithelial cell lineMolecular levelMolecular studiesDihydrodiol dehydrogenaseReductase expressionHDI exposureSubcytotoxic concentrationsCell linesMessage levelsImportant sensorMRNA levelsCellsWide distribution of Plasmodium ovale in Myanmar
Win T, Lin K, Mizuno S, Zhou M, Liu Q, Ferreira M, Tantular I, Kojima S, Ishii A, Kawamoto F. Wide distribution of Plasmodium ovale in Myanmar. Tropical Medicine And International Health 2002, 7: 231-239. PMID: 11903985, DOI: 10.1046/j.1365-3156.2002.00857.x.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPolymerase chain reactionPlasmodium ovaleP. ovaleP. ovale-infected patientsThin smearsPCR-positive patientsPlasmodium ovale infectionNested polymerase chain reactionHuman malaria parasiteSingle-species infectionsOvale infectionsP. malariaeQuadruple infectionsP. vivaxBlood samplesP. falciparumOvaleMalaria parasitesPatientsPlasmodium speciesInfectionChain reactionMolecular diagnosis
2000
Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates.
Liu Q, Ferreira M, Ndawi B, Ohmae H, Adagu I, Morikawa T, Horii T, Isomura S, Kawamoto F. Sequence diversity of serine repeat antigen gene exon II of Plasmodium falciparum in worldwide collected wild isolates. The Southeast Asian Journal Of Tropical Medicine And Public Health 2000, 31: 808-17. PMID: 11414433.Peer-Reviewed Original ResearchCitations
1999
How Prevalant are Plasmodium ovale and P. malariae in East Asia?
Kawamoto F, Liu Q, Ferreira M, Tantular I, Kawamoto F, Liu Q, Ferreira M, Tantular I. How Prevalant are Plasmodium ovale and P. malariae in East Asia? Trends In Parasitology 1999, 15: 422-426. PMID: 10481157, DOI: 10.1016/s0169-4758(99)01511-2.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPlasmodium ovaleMalaria parasitesIntense malaria transmissionHuman malaria parasiteAlternative diagnostic methodPlasmodium malariaeP. malariaeLow prevalenceMalaria speciesMalaria transmissionAcridine orange stainingMalariaeDiagnostic methodsOrange stainingOvalePrevalenceMorphological criteriaPCRAcridine orangeParasites
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