Jennifer Nelson
About
Research
Publications
2026
A Systematic Process for Assessing Fitness‐for‐Purpose of Health Outcomes for Computable Phenotyping With Electronic Health Record Data
Gatto N, Cronkite D, Wartko P, Ball R, Carrell D, Eniafe R, Desai R, Floyd J, Lee T, Nelson J, Shebl F, Schoeplein R, Toh S, Zhang M, Dublin S, Hernández‐Muñoz J. A Systematic Process for Assessing Fitness‐for‐Purpose of Health Outcomes for Computable Phenotyping With Electronic Health Record Data. Pharmacoepidemiology And Drug Safety 2026, 35: e70346. PMID: 41820261, DOI: 10.1002/pds.70346.Peer-Reviewed Original ResearchConceptsElectronic health record dataElectronic health recordsAdministrative claims dataComputable phenotypeHealth outcomesClaims dataLongitudinal EHR dataHealth recordsPublic health importanceEHR dataClinical carePhenotyping algorithmsHealth importanceRecord dataClinical informationData complexitySystematic processResource-intensiveNatural language processingOutcomesAssessment processDiagnostic testsLaboratory test resultsCareHealthEstimating Risk Differences Using Large Healthcare Data Networks for Medical Product Post‐Market Safety Outcomes in a Distributed Data Setting and Allowing for Active Post‐Market Surveillance
Cook A, Wellman R, Marsh T, Tiwari R, Nguyen M, Russek‐Cohen E, Peng Y, Nelson J. Estimating Risk Differences Using Large Healthcare Data Networks for Medical Product Post‐Market Safety Outcomes in a Distributed Data Setting and Allowing for Active Post‐Market Surveillance. Statistics In Medicine 2026, 45: e70440. PMID: 41760378, DOI: 10.1002/sim.70440.Peer-Reviewed Original ResearchConceptsRisk differenceInverse probability of treatment weightingRare event settingInverse probability of treatment weighting approachInverse probabilityRisk difference estimatesPatient-level dataHealthcare organizationsSequential monitoring boundaryProbability of treatment weightingDeidentified dataHealthcare networkSurveillance studySafety surveillance studyRisk of febrile seizuresTreatment weightingPropensity scoreHealthcareMonitoring boundaryRiskSafety risksPost-marketing surveillanceSafety outcomesMedical productsDistributed data setsAssessing Treatment Effects in Observational Data With Missing Confounders: A Comparative Study of Practical Doubly‐Robust and Traditional Missing Data Methods
Williamson B, Krakauer C, Johnson E, Gruber S, Shepherd B, van der Laan M, Lumley T, Lee H, Hernández‐Muñoz J, Zhao F, Dutcher S, Desai R, Simon G, Shortreed S, Nelson J, Shaw P. Assessing Treatment Effects in Observational Data With Missing Confounders: A Comparative Study of Practical Doubly‐Robust and Traditional Missing Data Methods. Statistics In Medicine 2026, 45: e70366. PMID: 41636549, PMCID: PMC12875654, DOI: 10.1002/sim.70366.Peer-Reviewed Original ResearchConceptsInverse-probability weightingMultiple imputationElectronic health record dataElectronic health record cohortPlasmode simulation studyHealth record dataMissing confoundersMissing data methodsRecord dataConfounding dataRare outcomesConfoundingAnti-depressant therapyMissingnessMissingness scenariosTreatment effectsDoubly-robust estimatorMaximum likelihood estimationMissingness proportionsData sourcesAnalysis approachBias-variance trade-offGeneralized rakingPharmacoepidemiologyComplex data structuresIncident Epilepsy and Vaccination Status or Vaccine Aluminum Exposure in Children Under Age 4
McClure D, Hanson K, Sundaram M, Kieke B, Duffy J, McNeil M, Glanz J, Irving S, Williams J, Kharbanda E, Xu S, Zerbo O, Nelson J, Belongia E, Weintraub E. Incident Epilepsy and Vaccination Status or Vaccine Aluminum Exposure in Children Under Age 4. The Journal Of Pediatrics 2026, 292: 115004. PMID: 41565005, DOI: 10.1016/j.jpeds.2026.115004.Peer-Reviewed Original ResearchIncident epilepsyRisk of epilepsyYears of ageDiagnosis codesOdds ratioVaccination statusConditional logistic regressionAdjuvant formulationsCase-control studyAntiseizure medication prescriptionsUp-to-dateVaccine Safety Datalink sitesMedication prescriptionsSecondary analysisStatus categoriesCumulative aluminum exposureAluminum exposureLogistic regressionConfidence intervalsAssociated riskPrimary analysisStatistically significant relationshipAge groupsAge subgroupsAntiseizure medicationsThe impact of a monthly unconditional cash transfer on child brain activity: A 4-year follow-up
Troller-Renfree S, Costanzo M, Duncan G, Magnuson K, Gennetian L, Yoshikawa H, Black S, Karhson D, Georgieff M, Nelson J, Nelson T, Fox N, Noble K. The impact of a monthly unconditional cash transfer on child brain activity: A 4-year follow-up. Developmental Cognitive Neuroscience 2026, 78: 101673. PMID: 41576765, PMCID: PMC12861262, DOI: 10.1016/j.dcn.2026.101673.Peer-Reviewed Original ResearchConceptsGifted groupFirst-year studyMonthly unconditional cash transfersChildren's brain activityUnconditional cash transfersEarly childhood povertyPreschool yearsPreschoolCash transfersChild's lifeGamma powerExploratoryYears of ageChildhood povertyYear studyAlpha powerFrontal gamma powerBrain activityChildrenFollow-upLow-incomeAnalytic planNo group differencesExploratory analysisBrain developmentP-1494. Risk of immune thrombocytopenia after second dose of a measles containing vaccine
Zerbo O, Modaressi S, Fireman B, Ross P, Goddard K, Nelson J, Glanz J, Irving S, Lewin B, DeSilva M, Williams J, Sundaram M, Klein N. P-1494. Risk of immune thrombocytopenia after second dose of a measles containing vaccine. Open Forum Infectious Diseases 2026, 13: ofaf695.1678. PMCID: PMC12792874, DOI: 10.1093/ofid/ofaf695.1678.Peer-Reviewed Original ResearchRisk of immune thrombocytopeniaMeasles-containing vaccineImmune thrombocytopeniaRelative riskVaccine Safety DatalinkDisease Control and PreventionITP casesControl and PreventionMeasles-containing vaccine dosesInstitutes of HealthRisk intervalDays prior to vaccinationAged 4Elevated riskCenters for Disease Control and Prevention's Vaccine Safety DatalinkConfidence intervalsMedical record reviewCenters for Disease Control and PreventionInternational ClassificationCenters for Disease ControlPlatelet countRetrospective studySecond doseRubella vaccineChildren Aged 4
2025
Navigating the Emotional Challenges of Grade School: The Influence of Early Family Strains and a Lack of Parental Responsiveness on Trajectories of Anxiety and Depressive Symptoms
Lopez M, Brock R, James T, Nelson J, Espy K, Nelson T. Navigating the Emotional Challenges of Grade School: The Influence of Early Family Strains and a Lack of Parental Responsiveness on Trajectories of Anxiety and Depressive Symptoms. Family Process 2025, 65: e70101. PMID: 41449805, PMCID: PMC12741509, DOI: 10.1111/famp.70101.Peer-Reviewed Original ResearchConceptsTrajectories of anxietyNegative affectDepressive symptomsConditional indirect effectResponsive parentingInternalizing problemsChild temperamental negative affectivityAssociated with child anxietyLevels of negative affectChildren's trajectoriesTemperamental negative affectivityChildren's negative affectHigher negative affectDevelopment of anxietyEmotional challengesChildren's emotional developmentFamily strainGrade schoolAssociated with higher levelsLack of parental responsivenessSymptom changeChild anxietyGrade 4Family processesAnxietyEvaluating bidirectional, longitudinal associations between adolescent executive control and eating behaviors
Thilges H, Phillips E, Goldberg E, Brock R, Kidwell K, Yaroch A, Hill J, Espy K, Nelson J, Mason W, Nelson T. Evaluating bidirectional, longitudinal associations between adolescent executive control and eating behaviors. Appetite 2025, 218: 108400. PMID: 41338289, PMCID: PMC12704826, DOI: 10.1016/j.appet.2025.108400.Peer-Reviewed Original ResearchExecutive controlEating behaviorsAdolescent ECCollection of cognitive processesLongitudinal associationsTime 2 assessmentsAdolescent eating behaviorsExecutive functionAutoregressive controlsEC tasksOne-year intervalCognitive processesStructural equation modelingTime 1Vegetable intakeTask performanceMultiple 24-h dietary recallsCognitive developmentIntervention targetsLatent factorsMethodological limitationsPoor dietary qualityLongitudinal studyEatingAdolescentsExamining longitudinal associations between early environmental deprivation and unpredictability and dietary quality and eating behaviors a decade later
Goldberg E, Brock R, Yaroch A, Hill J, Mason W, Nelson J, Espy K, Nelson T. Examining longitudinal associations between early environmental deprivation and unpredictability and dietary quality and eating behaviors a decade later. Appetite 2025, 216: 108277. PMID: 40882821, PMCID: PMC12554352, DOI: 10.1016/j.appet.2025.108277.Peer-Reviewed Original ResearchDietary qualityEating behaviorsCaloric intakeLongitudinal associationsMeasures of dietary qualityEmotional eatingAssociated with lower caloric intakeDietary assessment toolsCaregiver self-reportAssociated with higher caloric intakeLow caloric intakeHigh caloric intakeEarly deprivationDietary recallsSocioeconomic statusMaternal educationTFEQ-R18Prevention effortsSelf-ReportAssessment toolAssociated with eatingDimensions of early adversityStudy entryR-18EatingCash Transfers and Their Effect on Maternal and Young Children’s Health
Duncan G, Magnuson K, Kunin-Batson A, Yoshikawa H, Fox N, Halpern-Meekin S, Ainsworth N, Black S, Nelson J, Nelson T, Georgieff M, Karhson D, Gennetian L, Noble K. Cash Transfers and Their Effect on Maternal and Young Children’s Health. JAMA Pediatrics 2025, 179: 867-875. PMID: 40522644, PMCID: PMC12171960, DOI: 10.1001/jamapediatrics.2025.1612.Peer-Reviewed Original ResearchMonthly unconditional cash transfersBody mass indexHealth of mothersChild healthPhysical healthBMI percentileMental healthMother-infant dyadsUnconditional cash transfersLow-incomeChild body mass indexMental health of mothersMaternal reportPhysical health of mothersChild BMI percentileMaternal mental healthMaternal depressive symptomsChild's fourth birthdayDetect group differencesCash transfersGroup differencesPostpartum wardMother-child dyadsChildren's HealthMinneapolis/St Paul