Voluntary Faculty
Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsIsil Yildiz, MD, MPH
Assistant Clinical ProfessorDownloadHi-Res Photo
About
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Titles
Affiliated Faculty, Yale Institute for Global Health
Appointments
Pathology
Assistant Clinical ProfessorPrimary
Other Departments & Organizations
Education & Training
- Fellowship
- Icahn School of Medicine at Mount Sinai (2014)
- Resident
- University of Pittsburgh Medical Center (2013)
- MPH
- University of Pittsburgh Graduate School of Public Health (2013)
- Resident
- Hacettepe University Faculty of Medicine (2007)
- MD
- Gazi University School of Medicine (2002)
Research
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Overview
Public Health Interests
Bioinformatics; Biomarkers; Cancer; Chronic Diseases; Community Health; Global Health; Health Care Quality, Efficiency
Research at a Glance
Publications Timeline
A big-picture view of Isil Yildiz's research output by year.
13Publications
346Citations
Publications
2025
An update on applications of digital pathology: primary diagnosis; telepathology, education and research
Zia S, Yildiz-Aktas I, Zia F, Parwani A. An update on applications of digital pathology: primary diagnosis; telepathology, education and research. Diagnostic Pathology 2025, 20: 17. PMID: 39940046, PMCID: PMC11817092, DOI: 10.1186/s13000-025-01610-9.Peer-Reviewed Original ResearchCitationsMeSH Keywords and Concepts
2016
The Value of Papanicolaou Tests in the Diagnosis of Endometrial Carcinoma
Serdy K, Yildiz-Aktas I, Li Z, Zhao C. The Value of Papanicolaou Tests in the Diagnosis of Endometrial Carcinoma. American Journal Of Clinical Pathology 2016, 145: 350-354. PMID: 27124917, DOI: 10.1093/ajcp/aqv085.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPap test resultsAbnormal glandular cellsEndometrial carcinomaHistological diagnosisCervical involvementLymphovascular invasionPap testPresence of cervical involvementPresence of lymphovascular invasionCases of endometrial carcinomaDetection of endometrial carcinomaDiagnosis of endometrial carcinomaEndometrial carcinoma diagnosisBenign endometrial cellsGlandular cellsLow FIGO stageDepth of invasionCervical PapanicolaouGlandular abnormalitiesFIGO stageTumor sizePap smearPapanicolaou testPathology archivesTumor featuresRespiratory Cytology—Current Trends Including Endobronchial Ultrasound-Guided Biopsy and Electromagnetic Navigational Bronchoscopy: Analysis of Data From a 2013 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology
Sturgis C, Marshall C, Barkan G, Booth C, Kurtycz D, Souers R, Keylock J, Tabatabai Z, Russell D, Moriarty A, Doyle M, Thomas N, Yildiz-Aktas I, Collins B, Laucirica R, Crothers B. Respiratory Cytology—Current Trends Including Endobronchial Ultrasound-Guided Biopsy and Electromagnetic Navigational Bronchoscopy: Analysis of Data From a 2013 Supplemental Survey of Participants in the College of American Pathologists Interlaboratory Comparison Program in Nongynecologic Cytology. Archives Of Pathology & Laboratory Medicine 2016, 140: 22-8. PMID: 26717056, DOI: 10.5858/arpa.2014-0635-cp.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsElectromagnetic navigation bronchoscopyCollege of American PathologistsNongynecologic cytologyNavigation bronchoscopyEndobronchial ultrasound-guided biopsyMolecular testingCollege of American Pathologists Interlaboratory Comparison ProgramPrimary pulmonary adenocarcinomaAnaplastic lymphoma kinaseEpidermal growth factor receptorEndobronchial ultrasound-guided samplingUltrasound-guided biopsyCytology screening programsGrowth factor receptorUltrasound-guided samplingBronchial brushingsPulmonary adenocarcinomaBronchial washingsRespiratory cytologyBronchopulmonary specimensMinority of laboratoriesProcedure typeFactor receptorCytologyAspiration cases
2014
Discrepancy Reduction in a Cytopathology Fellowship Program as Demonstrated with a GYN Case Screening Log
Szporn A, Yildiz-Aktas I, Salem F, Wu M. Discrepancy Reduction in a Cytopathology Fellowship Program as Demonstrated with a GYN Case Screening Log. Journal Of The American Society Of Cytopathology 2014, 3: s9-s10. DOI: 10.1016/j.jasc.2014.09.020.Peer-Reviewed Original ResearchThe Value of the ThinPrep Test for Endometrial Carcinoma Diagnosis: A Large Study Cohort from an Academic Medical Center
Serdy K, Yildiz-Aktas I, Li Z, Zhao C. The Value of the ThinPrep Test for Endometrial Carcinoma Diagnosis: A Large Study Cohort from an Academic Medical Center. Journal Of The American Society Of Cytopathology 2014, 3: s2-s3. DOI: 10.1016/j.jasc.2014.09.006.Peer-Reviewed Original ResearchConceptsPrimary Pulmonary Non–Small Cell Carcinomas: The College of American Pathologists Interlaboratory Comparison Program Confirms a Significant Trend Toward Subcategorization Based Upon Fine-Needle Aspiration Cytomorphology Alone
Yildiz-Aktas I, Sturgis C, Barkan G, Souers R, Fraig M, Laucirica R, Khalbuss W, Moriarty A. Primary Pulmonary Non–Small Cell Carcinomas: The College of American Pathologists Interlaboratory Comparison Program Confirms a Significant Trend Toward Subcategorization Based Upon Fine-Needle Aspiration Cytomorphology Alone. Archives Of Pathology & Laboratory Medicine 2014, 138: 65-70. PMID: 24377813, DOI: 10.5858/arpa.2013-0015-cp.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsNon-small cell lung carcinomaSquamous cell carcinomaFine-needle aspirationCollege of American Pathologists Interlaboratory Comparison ProgramReference diagnosisGiemsa-stained smearsInterlaboratory Comparison ProgramConcordance rateFine-needleDiagnosis of adenocarcinomaCell lung carcinomaOptimal patient managementCytotechnologist responsesCell carcinomaLung carcinomaCytomorphological interpretationAdenocarcinomaMolecular testingPatient managementDiagnostic concordanceMixed model analysisMolecular triagePreparation typeCarcinomaStudy period
2012
The Effect of 96-Hour Formalin Fixation on the Immunohistochemical Evaluation of Estrogen Receptor, Progesterone Receptor, and HER2 Expression in Invasive Breast Carcinoma
Yildiz-Aktas I, Dabbs D, Cooper K, Chivukula M, McManus K, Bhargava R. The Effect of 96-Hour Formalin Fixation on the Immunohistochemical Evaluation of Estrogen Receptor, Progesterone Receptor, and HER2 Expression in Invasive Breast Carcinoma. American Journal Of Clinical Pathology 2012, 137: 691-698. PMID: 22523206, DOI: 10.1309/ajcpqrag67gjrpmt.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsProgesterone receptorEstrogen receptorCore biopsyResected samplesImmunohistochemical evaluationImmunohistochemical resultsEvaluation of estrogen receptorSemiquantitative H-scoreInvasive breast carcinomaCore biopsy specimensFormalin fixationASCO/CAP guidelinesHER2 testingBreast carcinomaHER2 expressionReceptor expressionBiopsy specimensH-scoreTumor heterogeneityIntraobserver variabilityHER2ReceptorsAmerican PathologistsBiopsyER resultsThe effect of cold ischemic time on the immunohistochemical evaluation of estrogen receptor, progesterone receptor, and HER2 expression in invasive breast carcinoma
Yildiz-Aktas I, Dabbs D, Bhargava R. The effect of cold ischemic time on the immunohistochemical evaluation of estrogen receptor, progesterone receptor, and HER2 expression in invasive breast carcinoma. Modern Pathology 2012, 25: 1098-1105. PMID: 22460807, DOI: 10.1038/modpathol.2012.59.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCold ischemic timeH-scoreASCO/CAP guidelinesIschemic timeHormone receptorsProgesterone receptorResected specimenAmerican Society of Clinical Oncology/College of American PathologistsImmunohistochemical evaluationEvaluation of estrogen receptorProlonged cold ischemic timeInvasive breast carcinomaH-score methodSignificant reductionBreast resection specimensAmerican SocietyNon-refrigerated samplesMild reductionBiopsy scoreBreast carcinomaCore biopsyEstrogen receptorBreast cancerTumor samplesIHC stainingLegionella micdadei prosthetic valve endocarditis complicated by brain abscess: Case report and review of the literature
Fukuta Y, Yildiz-Aktas I, Pasculle A, Veldkamp P. Legionella micdadei prosthetic valve endocarditis complicated by brain abscess: Case report and review of the literature. Infectious Diseases 2012, 44: 414-418. PMID: 22235842, DOI: 10.3109/00365548.2011.645506.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsProsthetic valve endocarditisMitral valve replacementValve endocarditisBrain abscessValve replacementDifferential diagnosisDifferential diagnosis of culture-negative endocarditisLegionella endocarditisHistory of mitral valve replacementDuration of antibiotic therapyRedo mitral valve replacementPeripheral-enhancing massDiagnosis of culture-negative endocarditisBrain magnetic resonance imagingCulture-negative endocarditisBuffered charcoal yeast extract agarCharcoal yeast extract agarLeft-sided weaknessMagnetic resonance imagingSilver impregnation stainPerivalvular abscessImmunocompromised womenValve cultureBlood culturesImmunocompromised patients
2011
Testicular touch preparation cytology in the evaluation of male infertility
Yildiz-Aktas I, Monaco S, Khalbuss W, Parwani A, Jaffe T, Pantanowitz L. Testicular touch preparation cytology in the evaluation of male infertility. CytoJournal 2011, 8: 24. PMID: 22279493, PMCID: PMC3263021, DOI: 10.4103/1742-6413.91244.Peer-Reviewed Original ResearchCitationsAltmetricConceptsEvaluation of male infertilityTouch preparationsMale infertilityCytological-histological correlationPresence of spermatogenesisAir-drying artifactTissue core biopsyStages of spermatogenesisConcurrent TPPathological spermatogenesisTestis biopsyTesticular biopsyTP slidesCore biopsyRare spermCytology specimensDiscordant casesSpecimen adequacyRare caseBiopsyRetrospective searchSpermatogenic elementsLow cellularitySpermatogenesisInfertility
Academic Achievements & Community Involvement
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Activities
activity “A Study on Healthcare Sustainability in Turkey: Workplace Satisfaction and Environmental Impact of Pathology Operations”
10/23/2020 - PresentOral Presentation29th National Pathology Congress, October 2019, Trabzon, Turkey.DetailsTrabzon, TurkeySponsored by Karadeniz Technical Universityactivity “A Status and Awareness Determination Study on Sustainability in Pathology Laboratories in Turkey”
10/16/2019 - PresentOral Presentation10th International Healthcare and Hospital Management CongressDetailsAntalya, TurkeySponsored by SAD – Health Academician Society, Turkeyactivity CAP Cytopathology Resource Committee
2012 - 2014CommitteesMemberDetailsJunior Member
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