Farnaz Najmi Varzaneh, MD
Assistant ProfessorCards
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Research
Publications
2025
Associations of TNF-Α -308 and -238 Polymorphisms with Inflammatory Bowel Disease: A Case-Control Study and Meta-Analysis of Published Data
Moosavi S, Shanker A, Sadr M, Soltani S, Shahkarami S, Farhadi E, Daryani N, Noveiry B, Varzaneh F, Bashashati M, Rezaei N. Associations of TNF-Α -308 and -238 Polymorphisms with Inflammatory Bowel Disease: A Case-Control Study and Meta-Analysis of Published Data. Immunology And Genetics Journal 2025 DOI: 10.18502/igj.v8i2.18003.Peer-Reviewed Original ResearchInflammatory bowel diseaseSingle nucleotide polymorphismsTNF-aMeta-analysisGene polymorphismsChronic relapsing-remitting inflammatory diseaseHealthy controlsBowel diseaseTumor necrosis factor-alphaAssociated with inflammatory bowel diseaseSusceptibility to inflammatory bowel diseasePathogenesis of inflammatory bowel diseaseNecrosis factor-alphaCase-control studySequence-specific primersFactor-alphaIranian patientsPolymerase chain reactionPCR-SSPInflammatory diseasesGenotype statusNucleotide polymorphismsAllele frequenciesCase-controlPatients
2021
Neurologic Manifestations of COVID-19
Delavari F, Varzaneh F, Rezaei N. Neurologic Manifestations of COVID-19. Advances In Experimental Medicine And Biology 2021, 1318: 343-353. PMID: 33973188, DOI: 10.1007/978-3-030-63761-3_20.Peer-Reviewed Original ResearchConceptsNeurological manifestationsPredisposition to multiple sclerosisPro-inflammatory stateManifestations of anosmiaCOVID-19 patientsAcute hemorrhagic encephalitisNeural invasionOlfactory bulbSystemic hyperinflammationNeurological symptomsSensory disturbanceAffected patientsAcute demyelinationManifestations rangeCerebrovascular injuryBrain stemHemorrhagic encephalitisGlial cellsMental statusEarly manifestationMultiple sclerosisNervous systemPatientsProlonged effectHyperinflammation
2020
Cancer Molecular and Functional Imaging
Najmi Varzaneh F, Baradaran Noveiry B. Cancer Molecular and Functional Imaging. 2020, 729-738. DOI: 10.1007/978-3-030-30845-2_31.Peer-Reviewed Original ResearchMagnetic resonance imagingPET/CTMolecular imagingEffective therapyFunction of organsEffective treatmentImmune pathwaysMolecular imaging techniquesResonance imagingTumor cellsCT imagingFunctional imagingCancer molecularEarly stagesTumorsStem cellsFluorescence imagingImagingTumor detectionGenetic characteristicsPatient's bodyImaging techniquesCellsCancerous cellsAgent distribution
2019
Baseline 3D-ADC outperforms 2D-ADC in predicting response to treatment in patients with colorectal liver metastases
Fouladi D, Zarghampour M, Pandey P, Pandey A, Varzaneh F, Ghasabeh M, Khoshpouri P, Kamel I. Baseline 3D-ADC outperforms 2D-ADC in predicting response to treatment in patients with colorectal liver metastases. European Radiology 2019, 30: 291-300. PMID: 31209620, DOI: 10.1007/s00330-019-06289-3.Peer-Reviewed Original ResearchConceptsShort-term response to treatmentResponse to treatmentHepatic colorectal metastasesPredicting response to treatmentColorectal metastasesSystemic chemotherapyPrediction of response to treatmentPercentile of ADCColorectal liver metastasesTrans-arterial chemoembolizationSystemic chemotherapy patientsBaseline ADCNonresponding lesionsRadioembolization patientsMetastatic lesionsLiver metastasesTACE patientsRadioembolizationPatientsChemotherapy patientsInclusion criteriaResponse to different treatmentsMR imagingTACEROI-basedPrognostic value of baseline volumetric multiparametric MR imaging in neuroendocrine liver metastases treated with transarterial chemoembolization
Luo Y, Pandey A, Ghasabeh M, Pandey P, Varzaneh F, Zarghampour M, Khoshpouri P, Ameli S, Li Z, Hu D, Kamel I. Prognostic value of baseline volumetric multiparametric MR imaging in neuroendocrine liver metastases treated with transarterial chemoembolization. European Radiology 2019, 29: 5160-5171. PMID: 30877462, DOI: 10.1007/s00330-019-06100-3.Peer-Reviewed Original ResearchConceptsHepatic progression-free survivalTreated with transarterial chemoembolizationNeuroendocrine liver metastasesOverall survivalApparent diffusion coefficientTumor volumeMultiparametric MR imagingArterial enhancementVenous enhancementBaseline MR imagingMR imagingIndex lesionsTransarterial chemoembolizationPrognostic factorsPredicting OSPrognostic valueDominant lesionMean apparent diffusion coefficientAssociated with favorable OSProgression-free survivalLower tumor volumeMethodsThis retrospective studyMultivariate survival analysisEvaluation of multiple lesionsMR parametersAdded value of apparent diffusion coefficient in distinguishing between serous and mucin-producing pancreatic cystic neoplasms
Pandey P, Pandey A, Shao N, Varzaneh F, Ghasabeh M, Zharghampour M, Khoshpouri P, Fouladi D, Eng J, O’Broin-Lennon A, Canto M, Hruban R, Kamel I. Added value of apparent diffusion coefficient in distinguishing between serous and mucin-producing pancreatic cystic neoplasms. European Radiology 2019, 29: 4660-4669. PMID: 30762111, DOI: 10.1007/s00330-019-6010-9.Peer-Reviewed Original ResearchConceptsPancreatic cystic neoplasmsApparent diffusion coefficientApparent diffusion coefficient measurementsDiffusion-weighted imagingCystic neoplasmsManagement of pancreatic cystic neoplasmsMorphological MRIValue of apparent diffusion coefficientAbdominal MRIEvaluate MRIDiagnostic confidenceDiagnostic performanceDiagnostic accuracyOdds ratioMRILogistic regressionNeoplasmsPatientsObjectivesToMorphological imaging
2018
Correlation between quantitative liver and spleen volumes and disease severity in primary sclerosing cholangitis as determined by Mayo risk score
Khoshpouri P, Ameli S, Ghasabeh M, Pandey A, Zarghampour M, Varzaneh F, Jacob A, Pandey P, Luo Y, Kamel I. Correlation between quantitative liver and spleen volumes and disease severity in primary sclerosing cholangitis as determined by Mayo risk score. European Journal Of Radiology 2018, 108: 254-260. PMID: 30396665, DOI: 10.1016/j.ejrad.2018.10.006.Peer-Reviewed Original ResearchConceptsMayo risk scorePrimary sclerosing cholangitisLiver volume ratioHigh-risk groupSpleen volumeRisk scoreSclerosing cholangitisSeverity of primary sclerosing cholangitisLeft lobeSingle center retrospective studyPrimary sclerosing cholangitis patientsROC analysisIntermediate risk groupDisease severityTotal liver volumeLiver volumeRetrospective studyCohort studyRisk groupsImaging studiesMayoLaboratory dataSpleenCholangitisAbsolute volumeAssociation of IL-10 and TGF-beta cytokine gene polymorphisms with autoimmune hepatitis
Yousefi A, Zare Bidoki A, Shafioyoun A, Sadr M, Varzaneh F, Shabani M, Motamed F, Farahmand F, Khodadad A, Fallahi G, Najafi M, Rezaei N. Association of IL-10 and TGF-beta cytokine gene polymorphisms with autoimmune hepatitis. Clinics And Research In Hepatology And Gastroenterology 2018, 43: 45-50. PMID: 30143451, DOI: 10.1016/j.clinre.2018.07.004.Peer-Reviewed Original ResearchConceptsAutoimmune hepatitisIL-10TGF-bAllele frequenciesIL-10 genetic variantsIL-10-1082 genotypesGenotype CCImmune-Mediated Liver InjuryAssociated with autoimmune hepatitisAllele CAssociation of IL-10Cytokine gene polymorphismsIL-10-1082Single nucleotide polymorphismsSequence-specific primersHaplotype TGGenetic variantsLiver antigenNucleotide polymorphismsCC haplotypeImmune-related genesGene polymorphismsHaplotype GCCPolymerase chain reactionHaplotypesLong-term follow-up of hepatic adenoma and adenomatosis: analysis of size change on imaging with histopathological correlation
Shao N, Pandey A, Ghasabeh M, Khoshpouri P, Pandey P, Varzaneh F, Zarghampour M, Fouladi D, Pawlik T, Anders R, Kamel I. Long-term follow-up of hepatic adenoma and adenomatosis: analysis of size change on imaging with histopathological correlation. Clinical Radiology 2018, 73: 958-965. PMID: 30031588, PMCID: PMC6440203, DOI: 10.1016/j.crad.2018.06.015.Peer-Reviewed Original ResearchRadiologist Revenue Change Following Multiple-Procedure Payment Reduction Modification
Noveiry B, Varzaneh F, Yousem D. Radiologist Revenue Change Following Multiple-Procedure Payment Reduction Modification. Journal Of The American College Of Radiology 2018, 15: 941-942. PMID: 29976355, DOI: 10.1016/j.jacr.2018.04.003.Peer-Reviewed Original Research
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