Diane Komp, MD
Professor Emeritus of PediatricsAbout
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Titles
Professor Emeritus of Pediatrics
Departments & Organizations
Education & Training
- MD
- SUNY at Brooklyn (1961)
Board Certifications
Pediatric Hematology-Oncology
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 1974
Pediatrics
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 1970
Research
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Research at a Glance
Publications Timeline
A big-picture view of Diane Komp's research output by year.
80Publications
3,342Citations
Publications
2002
Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation
Henter J, Samuelsson-Horne A, Aricò M, Egeler R, Elinder G, Filipovich A, Gadner H, Imashuku S, Komp D, Ladisch S, Webb D, Janka G, Society H. Treatment of hemophagocytic lymphohistiocytosis with HLH-94 immunochemotherapy and bone marrow transplantation. Blood 2002, 100: 2367-2373. PMID: 12239144, DOI: 10.1182/blood-2002-01-0172.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdolescentAge of OnsetBone Marrow TransplantationChildCytarabineDexamethasoneDrug Therapy, CombinationEtoposideFemaleFollow-Up StudiesHistiocytosis, Non-Langerhans-CellHumansImmunosuppressive AgentsMaleMitoxantroneReverse Transcriptase Polymerase Chain ReactionSurvival AnalysisTime FactorsConceptsBone marrow transplantationHLH-94Hemophagocytic lymphohistiocytosisMarrow transplantationTreatment of hemophagocytic lymphohistiocytosisProbability of survivalAccumulation of T lymphocytesSurvival of childrenAutosomal recessive diseaseCombination chemotherapyHistiocyte SocietyT lymphocytesTriggering of apoptosisFollow-upFamilial casesRecessive diseaseTherapeutic studyActivated macrophagesFamilial diseaseDiagnostic criteriaTransplantationPatientsLymphohistiocytosisSurvivalHistiocytes
2001
A randomized trial of treatment for multisystem Langerhans’ cell histiocytosis
Gadner H, Grois N, Arico M, Broadbent V, Ceci A, Jakobson A, Komp D, Michaelis J, Nicholson S, Pötschger U, Pritchard J, Ladisch S, Society F. A randomized trial of treatment for multisystem Langerhans’ cell histiocytosis. The Journal Of Pediatrics 2001, 138: 728-734. PMID: 11343051, DOI: 10.1067/mpd.2001.111331.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMultisystem Langerhans cell histiocytosisLangerhans cell histiocytosisDoses of corticosteroidsCell histiocytosisRandomized trialsLangerhans cell histiocytosis reactivationRisk organ involvementInternational Randomized StudyRandomized trial of treatmentTrials of treatmentDisease reactivationUntreated patientsTreatment failureDiabetes insipidusOrgan involvementPrognostic indicatorRandomized studyProbability of survivalEtoposideEffective treatmentWeek 6Mortality rateVinblastineCorticosteroidsHistiocytosis
1999
LCH I: A Randomized Trial of Treatment of Multisystem Langerhans Cell Histiocytosis
Ladisch S, Broadbent V, Ceci A, Jakobson A, Komp D, Michaelis J, Gadner H. LCH I: A Randomized Trial of Treatment of Multisystem Langerhans Cell Histiocytosis. Pediatric Research 1999, 45: 148-148. DOI: 10.1203/00006450-199904020-00882.Peer-Reviewed Original Research
1997
HLH‐94: A treatment protocol for hemophagocytic lymphohistiocytosis
Henter J, Aricò M, Egeler R, Elinder G, Favara B, Filipovich A, Gadner H, Imashuku S, Janka‐Schaub G, Komp D, Ladisch S, Webb D. HLH‐94: A treatment protocol for hemophagocytic lymphohistiocytosis. Pediatric Blood & Cancer 1997, 28: 342-347. PMID: 9121398, DOI: 10.1002/(sici)1096-911x(199705)28:5<342::aid-mpo3>3.0.co;2-h.Peer-Reviewed Original ResearchCitations
1994
VP-16 and the treatment of histiocytosis
Gadner H, Ladisch S, Aricó M, Broadbent V, Jakobson Å, Komp D, Nicholson S. VP-16 and the treatment of histiocytosis. European Journal Of Pediatrics 1994, 153: 389-389. PMID: 8033933, DOI: 10.1007/bf01956429.Peer-Reviewed Original ResearchCitationsLCH‐I: A randomized trial of etoposide vs. vinblastine in disseminated langerhans cell histiocytosis
Ladisch S, Gadner H, Arico M, Broadbent V, Grois N, Jacobson A, Komp D, Nicholson H. LCH‐I: A randomized trial of etoposide vs. vinblastine in disseminated langerhans cell histiocytosis. Pediatric Blood & Cancer 1994, 23: 107-110. PMID: 8202031, DOI: 10.1002/mpo.2950230207.Peer-Reviewed Original ResearchCitations
1992
Idiopathic neonatal iron-storage disease: Clinical similarity to hemophagocytic lymphohistiocytosis
Shneider B, Selsky C, Komp D. Idiopathic neonatal iron-storage disease: Clinical similarity to hemophagocytic lymphohistiocytosis. Gastroenterology 1992, 102: 1826. PMID: 1568600, DOI: 10.1016/0016-5085(92)91764-u.Peer-Reviewed Original ResearchCitationsA Mystery Story: Children, Cancer, and Covenant
Komp D. A Mystery Story: Children, Cancer, and Covenant. Theology Today 1992, 49: 68-74. DOI: 10.1177/004057369204900106.Peer-Reviewed Original ResearchCitationsHistiocytes in Familial and Infection-Induced/Idiopathic Hemophagocytic Syndromes May Exhibit Phenotypic Differences
Buckley P, O'Laughlin S, Komp D. Histiocytes in Familial and Infection-Induced/Idiopathic Hemophagocytic Syndromes May Exhibit Phenotypic Differences. Fetal And Pediatric Pathology 1992, 12: 51-66. PMID: 1348582, DOI: 10.3109/15513819209023280.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdolescentAntibodies, MonoclonalAntigens, CDAntigens, Differentiation, B-LymphocyteCD11 AntigensFemaleHistiocytesHistiocytosis, Non-Langerhans-CellHumansImmunoenzyme TechniquesImmunohistochemistryImmunophenotypingInfantInfant, NewbornMacrophagesMalePhenotypeReceptors, ComplementReceptors, Complement 3bReceptors, Complement 3dReceptors, Interleukin-2ConceptsInfection-associated hemophagocytic syndromeFamilial hemophagocytic syndromeM phi sHemophagocytic syndromeComplement receptorsPhi sFHS casesFrozen tissue sectionsHepatic dysfunctionLaboratory featuresMonocyte antigensNeurological manifestationsIdiopathic casesM phiClinical impressionFamily historyImmunoperoxidase techniqueAntigenic phenotypeHigh mortalitySporadic casesAntigen CD14Control tissuesSyndromeMonoclonal antibodiesFamily planningThe Patient's Ordeal By William F. May Bloomington, Indiana University Press, 1991. 218 pp. $24.95
Komp D. The Patient's Ordeal By William F. May Bloomington, Indiana University Press, 1991. 218 pp. $24.95. Theology Today 1992, 48: 496-500. DOI: 10.1177/004057369204800430.Peer-Reviewed Original Research