MPATH Faculty Search Webinar
September 25, 2024Information
- ID
- 12112
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Transcript
- 00:08Alright.
- 00:10Hello, everyone. I think, you
- 00:12are
- 00:13now being brought into our
- 00:15webinar.
- 00:16My name is Andy Goodman.
- 00:17I'm the director of the
- 00:19the chair of department of
- 00:20microbial pathogenesis and director of
- 00:22the microbial sciences institute at
- 00:24Yale School of Medicine.
- 00:25And,
- 00:27I'm gonna,
- 00:28use this time, to tell
- 00:30you a little bit about,
- 00:31the department, but really wanna
- 00:33have most of our time,
- 00:35to answer your your questions
- 00:37about the faculty search,
- 00:40about the position, about life
- 00:42in Connecticut,
- 00:43and anything else you may
- 00:44have have questions about.
- 00:47So I have a fantastic
- 00:49group of panelists here with
- 00:51me, and so maybe we'll
- 00:52start, with with introductions,
- 00:55from from them. Hesper, why
- 00:57don't you why don't you
- 00:58go first?
- 00:59Hi. My name is Hesper
- 01:01Rigo, and I'm an associate
- 01:03professor here in the department.
- 01:04My lab studies
- 01:06mycobacterial,
- 01:08pathogens at the level of
- 01:09single cells.
- 01:11And
- 01:12Yachi?
- 01:14Hi. My name is Yachi
- 01:15Ho. I'm associate professor also
- 01:16here at Microbial Pathogenesis.
- 01:19I work on mechanisms of
- 01:20HIV latency
- 01:22and some single cell genomics
- 01:23approaches.
- 01:25Great. And Craig.
- 01:28Hi. I'm Craig Roy. I'm
- 01:29a professor of microbial pathogenesis
- 01:31and immunobiology.
- 01:33I also serve as the
- 01:34director of the EOBBS graduate
- 01:37program, which is the large
- 01:38umbrella program that micro students
- 01:40enter through. So I'm happy
- 01:42to answer any questions you
- 01:43might have about the graduate
- 01:44program as well.
- 01:46And my lab studies, intracellular
- 01:48bacterial pathogens and how they
- 01:49manipulate the host.
- 01:52Great. Thank you.
- 01:54So,
- 01:54just briefly about about,
- 01:57the department of microbial
- 01:59pathogenesis.
- 02:01It was,
- 02:02founded over, twenty years ago
- 02:03initially as a section
- 02:05within the school of medicine
- 02:07and became a department,
- 02:09about ten years ago.
- 02:11There are currently,
- 02:13approximately ten,
- 02:14primary faculty,
- 02:16in addition to secondary faculty
- 02:17in the department,
- 02:20and they're primarily located in
- 02:22the Boyer Center at Yale
- 02:23School of Medicine, although there
- 02:24are some faculty who are
- 02:25at, West Campus.
- 02:29The,
- 02:30we're in the beginning of
- 02:31what I think is gonna
- 02:32be an exciting growth phase
- 02:33in the department.
- 02:35This is the second of
- 02:36what will be a series
- 02:37of of,
- 02:39faculty searches,
- 02:40that we've had, and and
- 02:42we're very excited that our,
- 02:44candidate last year recently accepted,
- 02:47her offer to come,
- 02:49join us in the department.
- 02:52In terms of the the
- 02:53faculty search, this is an
- 02:55open search,
- 02:56really open to all areas
- 02:58of
- 03:00microbial pathogenesis.
- 03:02We are interested in candidates
- 03:04focused on virology,
- 03:06parasitology,
- 03:06fungal biology, bacteria,
- 03:09who are using a wide
- 03:10range of approaches.
- 03:13The,
- 03:14applications
- 03:15are all through Interfolio.
- 03:16And if you have any
- 03:17questions about that process,
- 03:19I'm happy to to answer
- 03:20it.
- 03:22I can say briefly
- 03:24the way I think about
- 03:25about,
- 03:27recruiting,
- 03:28junior faculty is really through
- 03:29the lens of of two
- 03:30questions.
- 03:32The first is,
- 03:33how can we as a
- 03:34department
- 03:35help somebody
- 03:37do even better than they
- 03:38would otherwise?
- 03:39So we think a lot
- 03:40about,
- 03:41ways in which the support
- 03:43and mentorship and colleagues that,
- 03:45a candidate would have in,
- 03:47the Department of Microbial Pathogenesis
- 03:50could, allow them to do
- 03:52things even beyond
- 03:54what they would do do
- 03:55otherwise.
- 03:56And then the second question
- 03:58is, how would we as
- 03:59a department benefit from bringing
- 04:00on this new expertise? And
- 04:02so we're very interested in
- 04:03people who are thinking about
- 04:05things differently than the way
- 04:06we do,
- 04:08bringing in new approaches,
- 04:10new model systems, new organisms,
- 04:13etcetera.
- 04:15And,
- 04:16again, we really encourage you
- 04:18to apply. We've tried to
- 04:19make, the application,
- 04:21not too burdensome,
- 04:23and, again, are happy to
- 04:25answer,
- 04:26any of your questions about
- 04:28about, again, about the application
- 04:29process, about the position,
- 04:33the department,
- 04:34and the school of medicine
- 04:35and Yale in general.
- 04:37So the way to ask
- 04:39questions is actually to, just
- 04:41type them into the chat.
- 04:43That'll be visible only to
- 04:45the panel. So, again, we're
- 04:46keeping everything anonymous at this
- 04:48at this stage.
- 04:50So just type any questions
- 04:52you have in the chat,
- 04:54and then what I'll do
- 04:55is I'll look at them
- 04:56and
- 04:59make sure that that, there
- 05:01aren't redundant questions, then I'll
- 05:03read them back without your
- 05:04name,
- 05:05to,
- 05:06the audience, and then I'll
- 05:07ask, the panel to help
- 05:09with, providing their perspectives.
- 05:13So, yeah, look, go to
- 05:15the chat, start putting in
- 05:17in your questions. And while
- 05:18you're thinking about that, I'll
- 05:20just say one more thing,
- 05:22about the the momentum in
- 05:24microbiology
- 05:25here at Yale. You may
- 05:26have noticed that actually we
- 05:28have
- 05:28three faculty searches now open
- 05:31in microbiology.
- 05:32The one we're focused on
- 05:34today is,
- 05:36the search in the department
- 05:38of microbial pathogenesis.
- 05:40There are also two other
- 05:41searches in affiliation with the
- 05:42Microbial Sciences Institute, which is
- 05:45located at Yale's West Campus,
- 05:47and those are in partnership
- 05:48with the Department of Immunobiology
- 05:50and with the Department of
- 05:51Bioinformatics
- 05:52and Data Science.
- 05:53So those searches are separate.
- 05:55They have separate deadlines, separate
- 05:57review committees,
- 06:00and and I,
- 06:02so if you have questions
- 06:03about all these different searches,
- 06:05I'm also happy to, talk
- 06:06about that as well.
- 06:09So with that, I will,
- 06:12just start looking at the
- 06:13chat, and,
- 06:15please type in, any questions.
- 06:17Doesn't matter how simple,
- 06:19or how,
- 06:21complicated they are. If you
- 06:22have the question, I think,
- 06:24most likely other people do
- 06:25as well.
- 06:26I think here we won't
- 06:28focus on
- 06:30specific research programs.
- 06:33If your research program generally
- 06:35falls under the areas that
- 06:36are described in the ad,
- 06:38I would encourage you to
- 06:39apply,
- 06:40and I'm also happy to
- 06:43correspond with you by email
- 06:44if you have questions about
- 06:45your specific
- 06:47research program.
- 06:48Although I would add that,
- 06:49you know, the the, application
- 06:51is going to be evaluated
- 06:52by a by a committee,
- 06:54a search committee, and
- 06:56I wouldn't
- 06:58really interfere or get in
- 06:59front of their of their
- 07:01process.
- 07:03So
- 07:04yes, so please type your
- 07:05questions in the chat
- 07:08and maybe while we're waiting,
- 07:11panelists, if you have anything
- 07:12to add about,
- 07:14you know, one thing we
- 07:15could start with is is
- 07:16maybe your experience,
- 07:19starting your lab and coming
- 07:20to Yale,
- 07:22and,
- 07:23you know, what you can
- 07:24share about that.
- 07:28Craig, I don't know. To
- 07:30I can I can start
- 07:31a little bit? Been a
- 07:32long time for me, so
- 07:33I don't know if I'm
- 07:33the best person to speak.
- 07:36Yeah. Yachi, go ahead.
- 07:38Yeah. So I started here
- 07:39twenty seventeen. I would say
- 07:41this is a wonderful program.
- 07:42To tell the truth, before
- 07:44I came for this interview,
- 07:46I did not know anyone
- 07:47in this department. And this
- 07:48is a microbial pathogenesis department
- 07:51working on very solid side
- 07:52in molecular biology, microbial hosting
- 07:55interactions.
- 07:56I work on HIV and
- 07:57clinical samples. So when I
- 07:59applied, I really didn't know
- 08:00whether I got a chance
- 08:01or not. And I don't
- 08:02know. It's just very different
- 08:03approaches, and I just came.
- 08:05And then after I came,
- 08:06I figured out that people
- 08:07are doing very diverse things
- 08:09and every everyone in science
- 08:10is solid and people are
- 08:11nice and wonderful. So at
- 08:13that time, I talked to
- 08:14my chair saying, oh, what
- 08:15what should I bring here?
- 08:16What do you want me
- 08:17to do? And back then,
- 08:18doctor Jorge Galan said, you
- 08:20know, just do the best
- 08:21science. So I've been enjoying
- 08:23that and my very great
- 08:24scientific journey. There are wonderful
- 08:26people here, very, very solid
- 08:27course such as the genomics
- 08:29and microscope
- 08:30and many others and many
- 08:31other wonderful colleagues here at
- 08:33Yale. So I really enjoyed
- 08:34this, and I will feel
- 08:35that there's no
- 08:37specific pathogen or approach or
- 08:38anything.
- 08:39I I I would hope
- 08:40to have, you know, anyone
- 08:42having,
- 08:43some great science and fun
- 08:44stories to to join us.
- 08:49Esper, anything to add?
- 08:51Yeah. My my experience was
- 08:52very similar to Yachi. I
- 08:54started just slightly before
- 08:56she did. And,
- 08:58you know, one of the
- 08:59main reasons why I wanted
- 09:00to come to this department
- 09:01is that they were working
- 09:02on questions that I I
- 09:03found fascinating, and that was
- 09:05the direction that I wanted
- 09:06my lab to move it
- 09:07move to. You know, specifically,
- 09:09for me, it was really
- 09:10about host pathogen interactions. And
- 09:12to be able to come
- 09:13to a place that has,
- 09:14you know, done so much
- 09:15seminal work in that area
- 09:16was really,
- 09:18you know, really exactly where
- 09:19I wanted to land.
- 09:21So for me, it was
- 09:22it was really great to
- 09:23to start a lab here,
- 09:25and happy to, yeah, answer
- 09:27any questions related to that
- 09:28as well.
- 09:30Great.
- 09:31So our first few questions
- 09:32have started to, come in,
- 09:35and I may not do
- 09:36them exactly in order, but
- 09:38I will try to cover,
- 09:39everything.
- 09:41So,
- 09:42I'll start with,
- 09:44we one question is,
- 09:47is there a specific career
- 09:49stage that the department is
- 09:50focused on? So this search
- 09:53is focused on the assistant
- 09:54professor career stage,
- 09:57and
- 09:58and,
- 10:00this would be someone who,
- 10:02you know, in most cases
- 10:03is,
- 10:05completing their, you know, postdoctoral
- 10:07studies currently, although they could
- 10:09be in some other kind
- 10:10of training stage.
- 10:11But the search is is,
- 10:13focused on on,
- 10:15the assistant professor,
- 10:18stage.
- 10:21So the next question
- 10:27is, whether
- 10:29ongoing funding is ongoing funding
- 10:32a critical requirement for the
- 10:34candidate, or is the perspective
- 10:36capability of acquiring grants enough?
- 10:39Anyone
- 10:40in the panel wanna comment
- 10:41on that?
- 10:45I don't think we've
- 10:46ever,
- 10:48put a high,
- 10:53you know,
- 10:54target or whatever on do
- 10:56you already have funding.
- 10:58When when recruiting at the
- 10:59assistant professor level, we usually
- 11:01look at the potential for
- 11:04success,
- 11:05for synergy with existing members
- 11:08of the the department,
- 11:11for value added, new new
- 11:12approaches, new organisms,
- 11:14etcetera.
- 11:17And then,
- 11:20you know,
- 11:21we've always had confidence in
- 11:23the people that we select
- 11:25will not have problem getting
- 11:27their funding, and I think
- 11:28that's mostly panned out. So
- 11:33So a related question,
- 11:36was whether it's necessary to
- 11:38include a budget
- 11:40information in the statement of
- 11:41research plan. So I can
- 11:42add to that. The answer
- 11:43to that is no.
- 11:45We're really focused on,
- 11:48the scientific questions you do
- 11:50wanna answer, why those questions
- 11:52are important,
- 11:53why you're the right person
- 11:54to answer those questions, and
- 11:56how we can help,
- 11:58you reach even further than
- 11:59you would, otherwise.
- 12:04There are some,
- 12:05there's a question about,
- 12:07interdisciplinary
- 12:09research.
- 12:10You know, do we encourage
- 12:11interdisciplinary
- 12:12research? The answer to that
- 12:13is absolutely yes.
- 12:16You know, many of our
- 12:17current faculty
- 12:19are highly interdisciplinary
- 12:20in the work that they
- 12:21do.
- 12:22One thing that I've really
- 12:23appreciated about,
- 12:25Yale is that
- 12:27it is,
- 12:28a large enough institution that
- 12:30there are experts in really
- 12:32anything you could imagine, but
- 12:33it's also small enough that
- 12:34it's very easy to collaborate.
- 12:37It's common for,
- 12:40for me to get emails
- 12:41just out of the blue
- 12:42from other Yale faculty or
- 12:43their students saying, you you
- 12:45know, I'm also at Yale.
- 12:46I'm interested in this or
- 12:47that about the microbiome, and
- 12:48could we meet?
- 12:50And, again, I think that's
- 12:51part of,
- 12:52Yale being in this, nice,
- 12:55sweet spot of size
- 12:57that,
- 12:58facilitates those kinds of,
- 13:00easy collaborations.
- 13:04And and I I could
- 13:05just add to that, Anthony,
- 13:06that, you know, one to
- 13:08to pitch again the BBS
- 13:09graduate program, one of the
- 13:11nice things about this large
- 13:12umbrella graduate program is we
- 13:14have students coming in with
- 13:15many different scientific interests who
- 13:18cross pollinate and fertilize many
- 13:19labs in many different departments
- 13:21bringing in,
- 13:22new approaches, new ideas.
- 13:25And in in in many
- 13:26instances, even if the student
- 13:28doesn't join your lab,
- 13:30they become friends with someone
- 13:32in your lab, and and
- 13:33lots of collaborations, lots of
- 13:35ideas,
- 13:36of an interdisciplinary
- 13:38nature are formed simply by
- 13:40the the,
- 13:41students,
- 13:43having this opportunity to, you
- 13:45know, come into this large
- 13:46umbrella program, meet each other,
- 13:48learn about what they're doing,
- 13:49and and interact. So,
- 13:52the other thing I'd like
- 13:53to add to that is
- 13:54that, you know,
- 13:57I've always found Yale to
- 13:59be one of the most
- 13:59highly collaborative places
- 14:01that I've been, including many
- 14:03places on the West Coast
- 14:04and the East Coast,
- 14:06that shall not be named.
- 14:07And departmental lines here, although
- 14:09they're important for administrative
- 14:11reasons,
- 14:12they're really not important for
- 14:13scientific reasons. This is probably
- 14:15one of the the friendliest
- 14:17and most
- 14:19interactive and collaborative places across
- 14:21disciplines,
- 14:22that that I've experienced. And
- 14:24and without,
- 14:26you know, having great colleagues
- 14:27in cell biology, great colleagues
- 14:29in immunobiology,
- 14:30great colleagues in structural biology,
- 14:33I don't think we'd we
- 14:35would have ever been able
- 14:36to have the success that
- 14:37we've been able to achieve
- 14:39at at most other places.
- 14:42Craig, maybe this is a
- 14:43good chance for you to,
- 14:44just say a little bit
- 14:45about the BBS program and,
- 14:47you know, every school is
- 14:48different and maybe just about
- 14:50the umbrella versus the graduate
- 14:52programs and,
- 14:54how that fits together at
- 14:55Yale.
- 14:57Yeah. So so the BBS
- 14:58graduate program here at Yale
- 15:00is an umbrella program. So
- 15:01students enter through,
- 15:03what we call tracks, which
- 15:05the tracks themselves
- 15:07are focused on,
- 15:09more,
- 15:11specific scientific areas of investigation,
- 15:14ranging from immunobiology,
- 15:16cell biology,
- 15:18microbiology,
- 15:19computational biology,
- 15:20pharmacology, physiology.
- 15:23And but the students, when
- 15:25they enter one of these
- 15:26tracks, they're still part of
- 15:27the large umbrella program. They're
- 15:29free to rotate in any
- 15:30lab they want and join
- 15:31any lab they want.
- 15:33So of the sum, you
- 15:35know, I think we're up
- 15:35to now four hundred faculty
- 15:37that make up the BBS
- 15:38graduate
- 15:40program. It's it's very common
- 15:42to get students who,
- 15:45you know, enter through another
- 15:46track, and and you as
- 15:48a faculty member
- 15:49oftentimes participate in multiple tracks,
- 15:53and therefore recruit students from
- 15:55those tracks to be part
- 15:56of your lab.
- 15:58So it's really kind of
- 16:00nice in that the selection
- 16:02process for students is based
- 16:03on the tracks, so it
- 16:05spreads the workload out.
- 16:07But the students have unlimited
- 16:09opportunities to to rotate and
- 16:11join any lab they want.
- 16:13I would like to add
- 16:14on. I'm the director for
- 16:15the microbiology
- 16:17PC program.
- 16:18So we have about five
- 16:19to ten students each year.
- 16:21They frequently rotate in our
- 16:23faculty labs, but, also, we
- 16:25will get, like, students from
- 16:27other tracks such as iBio
- 16:28or, computer science and things
- 16:30like those. What I what
- 16:31Quake just said is that
- 16:33all students affiliated with Yale
- 16:34BBS can choose any PI,
- 16:36but then Yale is a
- 16:38is a close community with
- 16:39the sizes that is not
- 16:40that huge. So we our
- 16:42PS do get access to
- 16:43students, very, very often.
- 16:48Okay. The next question, I'm
- 16:50gonna answer part of it
- 16:51and ask Yachi to answer
- 16:52the other part.
- 16:54So the question is, if
- 16:55someone's involved in clinical research,
- 16:58is the main campus or
- 16:59west campus better in terms
- 17:01of hospital access,
- 17:02you know, in in light
- 17:03of the other faculty searches
- 17:05that are going going on?
- 17:08So I'll talk about the
- 17:09west campus and main campus
- 17:10part, and then, Yachi, maybe
- 17:11you can talk about,
- 17:13clinical samples and and and
- 17:15that kind of thing. So,
- 17:17in terms of the main
- 17:18campus and west campus, they're
- 17:20about five miles apart from
- 17:22each other.
- 17:23This position is,
- 17:25for,
- 17:26lab space at the medical
- 17:28school in the Boyer Center
- 17:29for Molecular Medicine,
- 17:33And and,
- 17:35so that's where where the
- 17:36lab will be.
- 17:38But in terms of the
- 17:39appointment
- 17:40in microbial pathogenesis,
- 17:44that's really the defining feature
- 17:46in terms of being a
- 17:47member of the school of
- 17:48medicine. So,
- 17:50the
- 17:51the,
- 17:52you know, being a member
- 17:53of the school of medicine
- 17:54at the West Campus or
- 17:55at,
- 17:57the the main campus, you
- 17:59would
- 18:00interface with the same programs
- 18:02for clinical collaboration either way.
- 18:05The hospitals indeed are
- 18:07located at the medical school,
- 18:09the main campus,
- 18:12but the interaction is very
- 18:13close because, again, it's five
- 18:16miles away. There's shuttles that
- 18:17run every twenty minutes, and
- 18:19everybody who's at the West
- 18:20Campus is a part of,
- 18:23some department,
- 18:24at the the, the main
- 18:26campus.
- 18:28So maybe, Yachi, you could
- 18:29talk a little bit about,
- 18:32clinical samples.
- 18:33Sure.
- 18:34I do work on clinical
- 18:35samples. For example, I get
- 18:37a blood and it's the
- 18:38other samples from people having
- 18:40HIV.
- 18:41This is like bread and
- 18:42butter just like
- 18:43someone would count mouse in
- 18:44the mouse house. So I
- 18:45would say their existing IRB
- 18:47and then their existing access
- 18:49to these, collaborators in the
- 18:50clinic. And I there there
- 18:52has been setting up of
- 18:53these, like, collaborations for, like,
- 18:55ten, twenty years, so I
- 18:56can easily approach these physicians.
- 18:57They are very happy to
- 18:59recruit participants. And then I
- 19:00do need to file ARB,
- 19:02but there are templates and
- 19:03the ARB crew would help
- 19:04us to file those. So
- 19:05I would say I don't
- 19:06have any any problems getting
- 19:08those samples. For example, recently,
- 19:09we tried to get a
- 19:11gut biopsy samples from the
- 19:12hospital. We get it every
- 19:13week. So, they're still sending
- 19:15procedures,
- 19:17a bit to for us
- 19:18to get access to these
- 19:19samples.
- 19:21Right.
- 19:23Okay. Thank you.
- 19:26The next question is about,
- 19:28core facilities
- 19:30at Yale. So what core
- 19:31facilities are accessible,
- 19:33that may be useful for,
- 19:36research in microbial pathogenesis?
- 19:41I can take at least
- 19:42part part of this question.
- 19:44So I mean, there's lots
- 19:46of core facilities. The one
- 19:48a lot,
- 19:49one that
- 19:50our lab and I know
- 19:51others here use is a
- 19:52flow cytometry core.
- 19:54That has been really amazing
- 19:56for us. In fact, when
- 19:57I first started the lab,
- 19:58I actually thought about buying
- 19:59our own flow cytometer,
- 20:01and, I have been so
- 20:02happy with the core.
- 20:04And it's a core that
- 20:05exists at all sorts of
- 20:06different biosafety levels all the
- 20:07way up to BSL three.
- 20:10And, so we've been very,
- 20:12very happy with that. There's
- 20:14microscopy cores all around.
- 20:16One of the great things
- 20:17about
- 20:18Yale is actually that imaging
- 20:20is, really strong here. So
- 20:22even if you can't find,
- 20:23like, a microscope that you
- 20:24need,
- 20:25in a core facility,
- 20:26chances are there might be
- 20:27one that someone has built
- 20:29somewhere and, could potentially help
- 20:31you use.
- 20:32So we've been very happy
- 20:34with those core facilities. I
- 20:35we've also used sequencing core
- 20:36facilities, and there's actually a
- 20:39a drug discovery core facility.
- 20:41There's,
- 20:42you know,
- 20:44pretty much if you want
- 20:45it somewhat, it probably is
- 20:46here.
- 20:49I would like to add
- 20:49on the sequencing facility because
- 20:51my lab does a lot
- 20:52of single cell sequencing
- 20:54and many fancy platforms. I
- 20:55I would say when I
- 20:56came here for a second
- 20:57visit, I talked to the
- 20:58YCGA director and he said
- 21:00that basically the dean gave
- 21:01him ten million dollars to
- 21:02make the best facility ever,
- 21:04for to support research use.
- 21:06And during the COVID time,
- 21:07for example, people want to
- 21:08sort, you know, COVID passing
- 21:10mouse samples and human samples.
- 21:11How dangerous would that be
- 21:12in the court? They are
- 21:13to say, we will make
- 21:14it happen under the best
- 21:16spouse safety and support your
- 21:17research. So, basically, Yale is
- 21:19a place that when the
- 21:20dean has extra funding, they
- 21:21put that into into core
- 21:23facilities that we have the
- 21:24best high end, you know,
- 21:26sequencing facility that sequencing here
- 21:28is one million reads, is
- 21:29one dollar. So it's pretty
- 21:30cheap compared with other institutes.
- 21:32So I would say there
- 21:33are many different cores available
- 21:34that do support the research
- 21:36program.
- 21:38And they've also invested heavily
- 21:40in cryo electron microscopes,
- 21:41including three Titan Krios as
- 21:44well as some other really
- 21:45nice microscopes and
- 21:47and FIB milling. So, you
- 21:48know, we're now doing,
- 21:51high throughput
- 21:52volume
- 21:53rendering through cells by by,
- 21:56cryo EM where we can
- 21:57get, you know, three d
- 21:58reconstructions of an entire infected
- 22:00cell in a matter of
- 22:02days,
- 22:03which is something that, you
- 22:04know,
- 22:05we tried ten years ago.
- 22:07It just wasn't possible, and
- 22:09it's all through the core
- 22:10facilities and the investments
- 22:11Yale has made in in
- 22:14these these cryo EM facilities,
- 22:16which are just phenomenal right
- 22:18now.
- 22:20Thanks.
- 22:22Another question. And now we
- 22:23have many questions, so I'm
- 22:24gonna do my best, to
- 22:27identify,
- 22:29go through all of them.
- 22:31How valuable are computational
- 22:33skills in this role? Is
- 22:34there a possibility they have
- 22:36a purely computational lab in
- 22:37the department?
- 22:38Maybe I'll answer that.
- 22:41There's quite a bit of
- 22:42of,
- 22:43computational focus in the department,
- 22:45including Yachi's lab as as
- 22:47one example.
- 22:49And, certainly, that's an example
- 22:51of an area where, we
- 22:54would,
- 22:56again, we're we're looking for
- 22:57labs that will,
- 22:59not only that we can
- 23:00help do better, that will
- 23:01help us do better. And
- 23:03so we're definitely open to
- 23:04people bringing in other techniques.
- 23:06You know, that said, we
- 23:08also it's very important to
- 23:09us that we can provide
- 23:10the best mentorship,
- 23:12possible for our junior faculty.
- 23:15And so I think it
- 23:16really would come down to
- 23:17the individual program and,
- 23:20convincing
- 23:21ourselves that that,
- 23:23you know, as a department
- 23:24of of, microbial pathogenesis that
- 23:26we can, again, provide the
- 23:28best mentorship for someone. So
- 23:30it depends on, I think,
- 23:31a purely computational lab. It
- 23:33would depend
- 23:34on the program and their
- 23:35goals and what kind of
- 23:36support they they need to
- 23:38do their best in terms
- 23:39of whether that would be
- 23:40a good match.
- 23:44The,
- 23:47there's a question about if
- 23:48you're potentially,
- 23:51eligible for more than one
- 23:52of these searches.
- 23:54Is it recommended to apply
- 23:55to both or just one?
- 23:57Probably better to apply to
- 23:59both. I mean, we'll be
- 24:00keeping an eye on all
- 24:02the searches together and interfacing.
- 24:04So if there are applications
- 24:06that come in through one
- 24:07search and are better suited
- 24:08for another, we will be
- 24:10able to,
- 24:12identify that,
- 24:13but probably best for you
- 24:14to apply for the searches
- 24:16that,
- 24:17you know, you think you're
- 24:18eligible and would be a
- 24:19good match, for you.
- 24:23Andy, correct me if I'm
- 24:24wrong, but the current MSI
- 24:26search isn't
- 24:27through microbial pathogenesis, meaning that
- 24:30people applying to that search
- 24:32will not be appointed
- 24:35to the department of microbial
- 24:36pathogenesis.
- 24:37So they won't be part
- 24:38of our cohort.
- 24:40Yes. That's exactly right. It's
- 24:41a these are separate searches.
- 24:44I think people who do
- 24:45us, you know, search on
- 24:46science careers for microbiology at
- 24:49Yale, all three of these
- 24:50will come up, which is
- 24:51why I wanted to highlight
- 24:52it. But those other searches
- 24:53are primary appointments in other
- 24:55departments.
- 24:56Again, one in bioinformatics and
- 24:58data science, the other in
- 25:00immunobiology.
- 25:04We there's a question about,
- 25:07is there a limit on
- 25:08the number of years after
- 25:09PhD for the candidate?
- 25:11And maybe we can kind
- 25:13of talk more broadly about,
- 25:16you know, what are the
- 25:18you know, whether or not
- 25:19we have limits and rules
- 25:21in that way in terms
- 25:22of who could be a
- 25:24a candidate.
- 25:25Well Does anyone I I
- 25:27don't think it's uncommon these
- 25:28days for people sometimes to
- 25:30have done two postdocs. Maybe
- 25:31they wanted to switch areas
- 25:32of interest
- 25:34after doing a four year
- 25:35postdoc or or explore another
- 25:37area.
- 25:38So, you know, the clock
- 25:39will be different for different
- 25:41people. I don't I don't
- 25:43think that we've ever, you
- 25:44know,
- 25:46looked at someone and said,
- 25:47oh, they've been in this
- 25:48position for postdoctoral position for
- 25:51seven years.
- 25:52That's too long.
- 25:53Right?
- 25:54I think it's, you know,
- 25:56more a matter of what
- 25:58questions are you
- 26:00investigating,
- 26:02you know, what what's your
- 26:03potential,
- 26:05going forward,
- 26:07and how can we
- 26:09mesh and and is it
- 26:11a good fit
- 26:12synergistically
- 26:13in the department? I I
- 26:15I would venture as a
- 26:17member of a search committee
- 26:18not to put a lot
- 26:19of,
- 26:21stock in kind of number
- 26:22of years post PhD that
- 26:25the the applicant has had.
- 26:27But if anyone feels differently,
- 26:28please No. I completely I
- 26:30completely agree.
- 26:32The the next question is
- 26:33about teaching. Maybe I'll throw
- 26:34this one to Hesper.
- 26:37Wondering about opportunities
- 26:39for teaching at the graduate
- 26:42level,
- 26:43which courses are available,
- 26:47changes or developing specific courses,
- 26:49and then also,
- 26:50teaching at the undergraduate level.
- 26:53Right. So the position that
- 26:55we're talking about is at
- 26:56at the medical school. So
- 26:57there isn't a formal undergraduate
- 27:00teaching requirement,
- 27:02as you know, this is
- 27:03very much in contrast if
- 27:04you were to apply to
- 27:05a department that,
- 27:07was at sort of the
- 27:08the main campus
- 27:10as as at least I
- 27:11call it.
- 27:12So this is so because
- 27:13of that, you know, we
- 27:14mostly teach graduate students and
- 27:16our core and our department
- 27:18administers,
- 27:20several courses,
- 27:21in,
- 27:23in
- 27:24microbiology. So we run a
- 27:25course, and I'm one of
- 27:26the course directors for the
- 27:28bacterial
- 27:29bacteriology course,
- 27:31that's really focused on bacterial
- 27:32pathogens
- 27:33and bacterial pathogenesis.
- 27:35And then we also,
- 27:37administer a course in virology.
- 27:40And those courses are very
- 27:41small. They're very geared towards,
- 27:43graduate students in their first
- 27:45and second year. They're, you
- 27:46know, often about five,
- 27:49students, and they're very seminar
- 27:51based.
- 27:52I will say that I
- 27:52also,
- 27:55am involved in teaching in
- 27:56other ways here. So I
- 27:57actually helped teach a microscopy
- 27:59course, through the department of
- 28:01cell biology. And I I
- 28:03do a few lectures even
- 28:04for the undergraduate,
- 28:06microscopy
- 28:07course as well. So there's
- 28:08definitely opportunities,
- 28:10to be involved in teaching
- 28:11in all different
- 28:12levels if that's something you're
- 28:14you're interested in. But it's
- 28:16certainly not a especially
- 28:17at the at the,
- 28:19undergraduate level, it's not a
- 28:20primary focus of of, what
- 28:23we do. That being said,
- 28:24of course, you know, you're
- 28:25teaching your graduate students in
- 28:26your lab and that's really,
- 28:27you know, at least how
- 28:28I view it, that's a
- 28:29primary source of, a mentorship
- 28:31and teaching,
- 28:32for for, you know, this
- 28:34type of position.
- 28:36Right. One thing that I
- 28:37really liked when when I
- 28:38came here having spent two
- 28:40years at another medical school
- 28:41for my first two years
- 28:42as a
- 28:43assistant professor is we weren't
- 28:45responsible for teaching the medical
- 28:47students medical microbiology.
- 28:49That's all done by the
- 28:50clinical departments. We don't have
- 28:51to teach any of the
- 28:52the medical students,
- 28:55which I like.
- 28:59I would like to clarify
- 29:01that these academic jobs, some
- 29:02are more teaching focused, such
- 29:03as, like, seventy five percent
- 29:04teaching,
- 29:05sponsored, kind of responsibilities, but
- 29:07our department are, mostly mostly
- 29:09research focused. So I teach
- 29:11no more than five classes,
- 29:13three to five class. It's
- 29:14like a three to five
- 29:15hours
- 29:16a year. So we are
- 29:17focusing on research.
- 29:20Yep. I mean, we we
- 29:22continually evolve these courses, and
- 29:24so there's always opportunities to
- 29:26bring in new areas.
- 29:28I did that when I
- 29:29was course director. Hesper's done
- 29:30that quite a bit now
- 29:32as as course director.
- 29:34So there is opportunity are
- 29:35opportunities to,
- 29:37expand our teaching. But like
- 29:39Yachi said,
- 29:41the typical
- 29:42teaching contribution
- 29:44is,
- 29:45you know, maybe one or
- 29:46two lectures per semester,
- 29:49in a in a small
- 29:50group format.
- 29:53Good. So I think I
- 29:54mean, there are there's been
- 29:55many questions on the chat
- 29:56about teaching. Hopefully, that covered,
- 29:58the gist of it, and
- 29:59you're welcome to email me
- 30:01if your question wasn't wasn't
- 30:02answered,
- 30:04as well.
- 30:15So there's a question about
- 30:18kind of about fit on
- 30:20the topic
- 30:22and
- 30:24getting a sense for for
- 30:25students
- 30:27and
- 30:28publications
- 30:29from PhD students before graduating.
- 30:31So maybe the first one
- 30:32is is what kind of
- 30:34conferences
- 30:34do our students typically go
- 30:37to?
- 30:41Anyone wanna share about that?
- 30:46You know, large society
- 30:48meetings, you know, the ASM
- 30:50general meeting,
- 30:52you know, there's a big,
- 30:54I know, virology meeting. A
- 30:55lot of the virology students
- 30:56go to each year.
- 30:58The Cold Spring Harbor meetings.
- 31:00Cold Spring Harbor is very
- 31:01accessible to here, so a
- 31:02lot of people go to,
- 31:04meetings at Cold Spring Harbor
- 31:06that are related to their,
- 31:08field of study.
- 31:10The Gordon Research Conferences are
- 31:12are a very popular
- 31:14series and and very diverse,
- 31:16so there's always subject areas
- 31:18that,
- 31:20you know, are within the
- 31:22scope of what we do
- 31:22here in the Gordon Research
- 31:24Conferences,
- 31:26as well as, you know,
- 31:27smaller workshops and and international
- 31:30meetings.
- 31:32I think our students are
- 31:34well represented at at a
- 31:35lot of these meetings and
- 31:36and are often selected,
- 31:39as, you know,
- 31:40speakers for ten minute talks.
- 31:45Thank you.
- 31:46We have a question.
- 31:47I'm not sure how well
- 31:48we can answer this, but
- 31:49someone asked about the competitiveness
- 31:52for this application.
- 31:54I think what I can
- 31:55say there is,
- 31:57that,
- 31:59we
- 32:00well, first thing I can
- 32:01say is that we do
- 32:03have the possibility of offering
- 32:04multiple,
- 32:06positions,
- 32:08and that will again depend
- 32:09on on the applications we
- 32:10get.
- 32:11So there there, again, there
- 32:13may be more than one
- 32:14even within this microbial pathogenesis
- 32:16search, there may be the
- 32:17possibility of of offering more
- 32:19than one person
- 32:22a job offer.
- 32:24Every application will be read
- 32:26by multiple members of,
- 32:29of the search committee as
- 32:30well.
- 32:31And oftentimes,
- 32:33when we do this initial
- 32:35review,
- 32:36if there's any applications where
- 32:39even if one committee member,
- 32:42was was less enthusiastic, if
- 32:44there's a split score,
- 32:45we'll take the time as
- 32:47a group to discuss the
- 32:48application, together.
- 32:50So your application will be
- 32:51looked at, very carefully, again,
- 32:53by multiple people,
- 32:55on the search committee,
- 32:57and and we also do
- 32:59have the at least the
- 33:00possibility of offering multiple,
- 33:03positions out of this one
- 33:04search.
- 33:06The next question,
- 33:08maybe I'll ask one of
- 33:09my panelists, maybe multiple
- 33:11panelists to comment on,
- 33:13is, talking about resources for
- 33:16junior faculty support
- 33:17in terms of career development,
- 33:20NIH funding, and mentoring.
- 33:24Maybe I'll kind of start
- 33:26from my perspective as as
- 33:27chair, that I I consider,
- 33:29you know, mentoring junior faculty
- 33:31to be a main part
- 33:32of my job.
- 33:34And when junior faculty come
- 33:36in, we establish mentoring committees
- 33:38within the department,
- 33:40that meet with new faculty
- 33:42on a regular basis,
- 33:44to give guidance on all
- 33:45of the challenges that come
- 33:46up when you start a
- 33:47lab anywhere,
- 33:49including writing grants,
- 33:52and building your lab.
- 33:55In addition, there is,
- 33:57at the school of medicine,
- 33:59there's,
- 34:01a cohort of junior faculty
- 34:03across the school of medicine
- 34:04that in basic science that
- 34:06kinda come in around the
- 34:07same time
- 34:08and, connect together to talk
- 34:10with each other about,
- 34:12challenges and opportunities in starting
- 34:14a new lab. So there's
- 34:16both peer mentoring as well
- 34:17as faculty mentoring,
- 34:19going on in in the
- 34:20department.
- 34:21I often read,
- 34:23grant applications
- 34:24from junior faculty
- 34:26as well to provide a
- 34:27perspective and and guidance.
- 34:30And then we also have
- 34:32what we call faculty research
- 34:33in progress,
- 34:35talks
- 34:35within the department. These are
- 34:37faculty only,
- 34:38and it's time where everyone
- 34:40in all the faculty in
- 34:41the department are really focused
- 34:43on your research and using
- 34:44their experience,
- 34:46on study section and writing
- 34:47grants themselves to provide guidance,
- 34:50and that can be a
- 34:51very helpful way also for
- 34:52getting support on these kinds
- 34:54of things.
- 34:56Other panelists wanna comment on,
- 34:59resources
- 35:00and practices at Yale?
- 35:02I'd just like to point
- 35:03out, Andy, that we have
- 35:04a mandatory requirement
- 35:06for all
- 35:08PIs, including existing PIs if
- 35:10they haven't taken the the
- 35:12mentoring
- 35:13workshop,
- 35:14that they must now complete,
- 35:17a Yale
- 35:18sponsored mentoring workshop, which I
- 35:20think there's something like eight
- 35:22sessions over a semester,
- 35:25that was developed by the
- 35:27National
- 35:28Mentoring Research Network.
- 35:30And our our,
- 35:33instructors in this have been
- 35:34been trained through the this
- 35:36organization.
- 35:38So all of the all
- 35:40of the PIs
- 35:41have to complete this mentoring,
- 35:44workshop,
- 35:45in order to take PhD
- 35:46graduate students.
- 35:49And
- 35:50it's offered free of charge.
- 35:51And and
- 35:53on a on a semester
- 35:54each semester, we offer it
- 35:56to the new investigator. So
- 35:59you do get you do
- 36:00get,
- 36:02mentoring on being a mentor.
- 36:07Other comments?
- 36:10Yeah. The I think that
- 36:11all those things sort of
- 36:12cover it.
- 36:14You know, I when I
- 36:15was very first started, I,
- 36:17actually, Yale paid for me
- 36:19to go to
- 36:20a two day intensive mentoring
- 36:24workshop,
- 36:24that was overnight in a
- 36:26nearby town called Old Saybrook.
- 36:28And, you know, I still
- 36:29rely on the lessons that
- 36:31I learned from that. And,
- 36:33this is one of the
- 36:33things that, you know, when
- 36:34you're first beginning, you don't
- 36:36you don't really know how
- 36:37to manage, and you're really
- 36:38you know, I think it's
- 36:39a big challenge, and I
- 36:40think that Yale,
- 36:42acknowledges that it's a challenge
- 36:43and and really works to
- 36:44to help you out as
- 36:45an assistant
- 36:47professor. I and in terms
- 36:48of getting funding, you know,
- 36:49I,
- 36:51you know, I sat in
- 36:52in Jorge Galan's office for
- 36:54many many times with my
- 36:55r o one sort of
- 36:56splayed open, and, you know,
- 36:58we really went into it,
- 37:00and really and
- 37:02enormous, very detailed,
- 37:04you know, discussions, and it
- 37:06was,
- 37:07incredibly helpful. And, you know,
- 37:09I it was really through
- 37:10those discussions that I was
- 37:11able to to get my
- 37:12first r o one. So,
- 37:14I think the the, you
- 37:15know,
- 37:17the desire and the ability
- 37:18here is to help,
- 37:20new professors,
- 37:22you know, get the things
- 37:22that they need to succeed.
- 37:25I'll add on to that.
- 37:26You know, when I just
- 37:27came, I have this feeling
- 37:29that, at that time, it
- 37:30was doctor Jorge Golang as
- 37:31the chair. What the feeling
- 37:33he gave me is that
- 37:34if I'm not able to
- 37:35tenure, he will feel very,
- 37:36very sorry. So this is
- 37:37a department that in the
- 37:39very first year, he will
- 37:40keep asking me, actually, do
- 37:41you need this? Do you
- 37:42need that? I can do
- 37:43this. Do you want this?
- 37:44Do you want that? This
- 37:45is a department that you're
- 37:47trying all the best to
- 37:48support us to to grow,
- 37:49and I really enjoy this.
- 37:50And second, for the faculty
- 37:52faculty mentoring committee, you are
- 37:54not assigned with someone. You
- 37:55find someone, which I found.
- 37:57For example, I found an
- 37:58HIV person and and actually
- 37:59doctor Craig Roy works on
- 38:01having nothing to do with
- 38:02HIV, but he gave me
- 38:04such, wonderful
- 38:05advice career advices that I'm
- 38:07still talking to him, like,
- 38:08like, every week and very
- 38:09frequently.
- 38:10And I also reach out
- 38:11to other faculties at Yale
- 38:12such as doctor Joe Craft,
- 38:13Immuno Biology. There's no limit.
- 38:15And people are all very
- 38:17willing to help, and I
- 38:18really enjoy, like, working with
- 38:20me.
- 38:22We have a question,
- 38:25about,
- 38:26whether it's possible to submit
- 38:27more than three letters of
- 38:29reference.
- 38:30I think the form is
- 38:34is set for only three.
- 38:37And depending on the situation,
- 38:39you know, one
- 38:41one path there is to
- 38:42just select the three who
- 38:43would best be able to
- 38:44comment on you and your
- 38:46work.
- 38:47If the advisers like, in
- 38:49the case of multiple postdoc
- 38:51advisers,
- 38:52if they
- 38:53are if the project is
- 38:54collaborative and one of them
- 38:56can write
- 38:58on behalf of both of
- 38:59them, that's another
- 39:00possibility.
- 39:02If there's truly no way
- 39:03to identify which three can
- 39:05best represent
- 39:07your,
- 39:09your work, and it's not
- 39:11possible to have one of
- 39:12them
- 39:14integrate comments from more than
- 39:15one person, send me an
- 39:16email, and we'll figure out
- 39:17what to do there.
- 39:23Now we have lots of
- 39:24questions, so thank you. If
- 39:26I don't get to your
- 39:26question, please follow-up by email.
- 39:33Let's see.
- 39:34So,
- 39:36there's a question about
- 39:39funding opportunities,
- 39:40institutional
- 39:41or departmental funding opportunities available
- 39:43for
- 39:44new junior faculty.
- 39:47So we could maybe talk
- 39:48about the process, the internal
- 39:50grant process,
- 39:52for those,
- 39:53grant programs that the university
- 39:55can only put in one
- 39:56or two nominations.
- 39:59Anyone wanna talk about about
- 40:00that?
- 40:02Sure. So yeah. So in
- 40:03your first few years, there's
- 40:05you're gonna get a lot
- 40:06of emails about
- 40:07different junior faculty
- 40:09awards,
- 40:10many of which can only
- 40:11have one,
- 40:13person submitted from Yale. And
- 40:15so there's actually an internal
- 40:16Yale committee
- 40:17that reads applications from all
- 40:19over Yale and then selects
- 40:20one,
- 40:22maybe two, depending on the
- 40:23the foundation,
- 40:25to then go and compete
- 40:26nationally.
- 40:27So it's these are very,
- 40:30you know, very simple applications.
- 40:32Often, they're, like, two pages,
- 40:34and,
- 40:35and our department, I think,
- 40:37has had a pretty good
- 40:38history of actually getting,
- 40:40quite a few of those.
- 40:42Yeah. So and then there's
- 40:43yeah. I I think that
- 40:45that pretty much covers it.
- 40:46There's other there's actually some
- 40:47internal funding for postdocs and
- 40:49things like that that actually
- 40:50is a,
- 40:51new faculty,
- 40:52is quite helpful.
- 40:58And, you know, in addition,
- 40:59in terms of internal funding,
- 41:01the
- 41:02you know,
- 41:03our goal is really to
- 41:04set up junior faculty to
- 41:06be successful.
- 41:08When we provide a start
- 41:09up package, we think about,
- 41:12what the candidate's goals are
- 41:14in terms of developing their
- 41:15lab,
- 41:16and
- 41:18especially in the first three
- 41:19years. And the idea is
- 41:20that,
- 41:22that support,
- 41:24is will allow you to
- 41:26reach those goals for the
- 41:27first, three years
- 41:28of your,
- 41:31your time,
- 41:32as starting your lab. So
- 41:34that's a significant,
- 41:35initial,
- 41:38component of departmental,
- 41:40support.
- 41:42Certainly during COVID, the university
- 41:43and the school of medicine
- 41:44offered,
- 41:46faculty support specifically to junior
- 41:48faculty,
- 41:49to
- 41:51deal with the challenges that
- 41:53arose, during
- 41:54during the pandemic,
- 41:56and there's kind of a,
- 41:57there's also other,
- 41:59for example, programs for supporting
- 42:01a postdoc that are internal
- 42:04Yale supported programs that, multiple
- 42:06members of the department have
- 42:08have used.
- 42:12Let's see.
- 42:16There is a question about,
- 42:18I'm gonna paraphrase,
- 42:21you know, research program
- 42:23that
- 42:25has implications in human health
- 42:26and disease but is not
- 42:28directly related to pathogenesis.
- 42:32I think I would I
- 42:33mean, without knowing the specifics,
- 42:34I would still encourage,
- 42:36encourage applications
- 42:38there.
- 42:39The department is focused on
- 42:40microbial pathogenesis, and that's, I
- 42:42think, an area that we
- 42:43provide key expertise,
- 42:45that interfaces with many other
- 42:47areas of the university.
- 42:49So, again, our focus is
- 42:51on is on microbial pathogenesis,
- 42:53but also we're open minded
- 42:55in terms of of,
- 42:57individual
- 42:58applications.
- 43:02There should be a bug,
- 43:03though.
- 43:05Yes.
- 43:09No bug. Probably no no
- 43:11go.
- 43:12Yeah.
- 43:16Here's a question about the
- 43:18cover letter. You know, would
- 43:19it be helpful to
- 43:21highlight
- 43:23examples of mentorship or service
- 43:25in the in the cover
- 43:26letter or what should be
- 43:27in the cover letter?
- 43:29Everyone here is members of
- 43:30the search committee. What do
- 43:32you look at in the
- 43:32cover letter?
- 43:34Any comments there?
- 43:38I typically don't read cover
- 43:39letters, so I
- 43:46just being honest.
- 43:50Yeah. I think the most
- 43:50important component of your application
- 43:52is your is your description
- 43:53of your future research plans.
- 43:55I think We're really yeah.
- 43:57We're really looking for
- 43:59your vision of what your
- 44:00lab would look like, and
- 44:02I think that shines through
- 44:03a lot more in the
- 44:04in that component of the
- 44:05application than in a cover
- 44:07letter.
- 44:09Yeah.
- 44:10Yeah. I think writing a
- 44:11clear and concise,
- 44:13research statement that kind
- 44:15of lays out
- 44:18what you've done
- 44:19and where you wanna go
- 44:20in the future and how
- 44:22that interfaces
- 44:24with the department.
- 44:26That's really in the first
- 44:28pass of applications,
- 44:31kind of what
- 44:32I think most of the
- 44:33reviewers look at. It's kind
- 44:34of like, what's this person
- 44:35done? What do they want
- 44:37to do? And how does
- 44:38that fit into our mission?
- 44:40And
- 44:44I I would add that
- 44:45when we get to the
- 44:46interview stage, there will be
- 44:48you know, that's also an
- 44:49opportunity to learn more about
- 44:50your,
- 44:52perspective on mentorship and and
- 44:54experience, and that will include,
- 44:57meetings with trainees in the
- 44:58department.
- 44:59And we do,
- 45:01ask for their feedback too,
- 45:04once we get to that
- 45:05stage.
- 45:08Okay.
- 45:13There is a question
- 45:17about,
- 45:18you know,
- 45:20whether
- 45:21it's possible as a new
- 45:23faculty member to attract graduate
- 45:25students
- 45:26or postdocs?
- 45:31Graduate students love new labs
- 45:34to the point where I
- 45:35I often have to mentor
- 45:36new faculty that you don't
- 45:38need to take every graduate
- 45:39student that shows an interest
- 45:40in your lab and accept
- 45:41them into your lab. Take
- 45:42the ones that best fit
- 45:44your culture
- 45:45and best,
- 45:46you know,
- 45:49show an interest in what
- 45:50you're doing,
- 45:51because
- 45:53they will come
- 45:55to you, and they like
- 45:57new PIs. They like PIs
- 45:58who are still working in
- 45:59the lab.
- 46:01And and,
- 46:03I think some of the
- 46:04biggest challenges for new PIs
- 46:06here
- 46:07are they
- 46:09were desperate to have graduate
- 46:10students. They've taken three or
- 46:11four graduate students in the
- 46:13the the first two years,
- 46:14and now they're having problems
- 46:15with them
- 46:16because they didn't really select,
- 46:20appropriately.
- 46:22Getting them is not a
- 46:23problem. Yeah.
- 46:26Yeah. I think that's right.
- 46:27Yeah. We just our a
- 46:28brand new lab just started
- 46:29in our department, and she
- 46:30already has two graduate students
- 46:32that joined the first year.
- 46:33And I I had two
- 46:34join my my first year
- 46:36as well.
- 46:37So they they come they
- 46:38often come in pairs. It's
- 46:40yeah. It's not a problem.
- 46:42We have a question about,
- 46:44joint appointments.
- 46:46And is this possible
- 46:48after establishing an independent lab?
- 46:53Craig, maybe since you have
- 46:54a secondary appointment, do you
- 46:56wanna talk a little bit
- 46:57about about that?
- 46:59Sure. I mean, you know,
- 47:01when I got here,
- 47:03you know, we were actually
- 47:04so so I was one
- 47:05of the founding members of
- 47:06this department, and and we
- 47:08originally started as three people.
- 47:10And we were really run
- 47:12out of cell biology.
- 47:13So this department was kinda
- 47:15formed,
- 47:16with the understanding that we
- 47:18need to
- 47:19develop a better understanding between
- 47:21how
- 47:22microbes
- 47:23interact with the host and
- 47:24and manipulate the cell biology
- 47:26of the host. And cell
- 47:27biology was really big on
- 47:28bringing
- 47:29bugs here because there were
- 47:30no bug people.
- 47:33And we didn't need any
- 47:35sort of joint appointments to
- 47:36get cell biology students or
- 47:38or to interact with the
- 47:40cell biologists, and I never
- 47:41asked for
- 47:43a joint appointment because administratively,
- 47:46you know, what what was
- 47:48the reason behind it? I
- 47:49think you only want to
- 47:50have a joint appointment.
- 47:52Or maybe sometimes you don't
- 47:53even want to have a
- 47:54joint appointment, but you're asked
- 47:56to be a joint appointee
- 47:58because
- 47:59you do will contribute
- 48:03towards the mission of that
- 48:04department in
- 48:06in in other ways. So
- 48:08for instance, I'm a joint
- 48:09appointee in immunobiology,
- 48:11which means
- 48:12I teach, you know, the
- 48:14immunobiology
- 48:14course. I
- 48:16participate in a lot of
- 48:17the the
- 48:19the the faculty activities within
- 48:20that
- 48:21department. But I was a
- 48:22member of the immunobiology
- 48:24graduate program for ten years
- 48:25before they,
- 48:27you know, offered me a
- 48:28joint appointment, and I never,
- 48:30you know, requested one because
- 48:32why do you wanna look
- 48:33for more work than you
- 48:34already have?
- 48:36So so,
- 48:38you know, because of the
- 48:39umbrella program, because of the,
- 48:41you know, the lack of
- 48:43scientifically
- 48:44departmental lines are very meaningless
- 48:46here,
- 48:48there's not a lot of
- 48:49reasons to have a joint
- 48:50appointment unless,
- 48:52you're in a clinical department
- 48:55and you want access to
- 48:57graduate students because here at
- 48:59Yale,
- 49:00clinical faculty can't train graduate
- 49:03students. They don't have access
- 49:04to the the the PhD
- 49:06programs,
- 49:08unless they get a joint
- 49:09appointment with a basic science
- 49:11department.
- 49:12But the job we're talking
- 49:13about, you get a basic
- 49:15science
- 49:15appointment. So you're a member
- 49:17of the Graduate School of
- 49:18Arts and Sciences,
- 49:20and you are you're qualified
- 49:21to to
- 49:23mentor PhD students.
- 49:25So there there there's very
- 49:26few reasons why you would
- 49:27want to have a joint
- 49:28appointment. If you wanted one,
- 49:30you know, it's certainly something
- 49:31that can always be discussed
- 49:32and always be
- 49:34negotiated.
- 49:36But just to have a
- 49:36title by your name,
- 49:39you know, there's really no
- 49:40need for it.
- 49:43Great. The okay. We're gonna
- 49:45shift gears a bit. We
- 49:46got a question. What's it
- 49:47like raising kids around Yale?
- 49:49What do you typically do
- 49:50with them on the weekend?
- 49:53Well, we have a beach,
- 49:55lots of beaches,
- 49:56lots of zoos,
- 49:58lots of museums right here
- 50:00in new in New Haven.
- 50:01When my kids were little,
- 50:02the Peabody Museum was a
- 50:04favorite spot. They knew every
- 50:06single
- 50:07diorama,
- 50:08all the rocks, all of
- 50:09the dinosaurs.
- 50:12You know, there's music everywhere
- 50:14here, theater.
- 50:16You know,
- 50:18I have to say
- 50:19having had multiple opportunities to
- 50:22go to other institutions,
- 50:25one thing that's always kept
- 50:26me here at Yale
- 50:28other than just the remarkable
- 50:30colleagues, which is first and
- 50:31foremost,
- 50:32is just the ease of
- 50:33living here, raising a family,
- 50:36and the the the low
- 50:38stress
- 50:39involved in all of that.
- 50:41You know, Hesper and Yachi
- 50:43have
- 50:44little kids and a little
- 50:45older kids, so maybe they
- 50:46can comment on
- 50:48how how how that transition
- 50:49has gone for them since
- 50:51they've
- 50:51they've arrived.
- 50:54Yeah. I if you know,
- 50:55I'm not from Connecticut.
- 50:57And if you told me,
- 50:58like, ten years ago that
- 50:59I would be living in
- 51:00Connecticut, I would have probably
- 51:01laughed in your face, but
- 51:02I actually love living here.
- 51:04And I love specifically living
- 51:05in New Haven. I live
- 51:07right by the undergraduate campus.
- 51:09So I actually bike my
- 51:10kid around everywhere. And I
- 51:12bike him to school and
- 51:13then I bike to work,
- 51:14and, it's just very easy
- 51:16to live here in a
- 51:17way that in other,
- 51:19places, you know, with universities
- 51:21that are like, you know,
- 51:22it's not as easy.
- 51:23So, you know, I take
- 51:24my yeah. Like I like
- 51:26Craig said, I take I
- 51:26actually live right next to
- 51:27the Peabody, so we go
- 51:28there a lot.
- 51:30We, you know, we go
- 51:32we have we are members
- 51:33of a pool, so we
- 51:34go to the pool a
- 51:35lot. We go to the
- 51:36beach. We go you know,
- 51:37there's just so many cool
- 51:38things to do with kids.
- 51:40You go we we take
- 51:41him into New York City.
- 51:43You know, he likes going
- 51:44on train rides, things of
- 51:45that. And it it's just
- 51:46it's very easy, to live
- 51:48here. And and if you
- 51:49have kids, you know, all
- 51:50of us, I think, in
- 51:50the department have kids. Like,
- 51:51we can all talk about
- 51:53schools
- 51:54and all the you know,
- 51:55where to live and all
- 51:56of these things.
- 51:57But, you know, I'm I'm
- 51:58very happy here, and, it's,
- 52:00yeah.
- 52:01Now I think I will
- 52:02continue to talk about five
- 52:03hours about this. Basically,
- 52:05at your your start of
- 52:06your career, you're starting as
- 52:07assistant professor. You have a
- 52:08family to raise. This is
- 52:10really the best place because
- 52:11life is really easy. We
- 52:13we get the the the
- 52:14the price you spend in
- 52:15those big cities. I got
- 52:16a huge house. It's even
- 52:17the lawn is too big
- 52:18to mount. It's just it's
- 52:19just wonderful living here. There
- 52:21are many different activities. You
- 52:22can you can see, you
- 52:23know, near New Haven. Also,
- 52:25we go to New York
- 52:26a lot. We're very close
- 52:27to the beach. We're in
- 52:28the northeast.
- 52:29I would like to add
- 52:30on to this location thing
- 52:32is that because we're in
- 52:33New Haven, our living expenses
- 52:35way lower, not only to
- 52:36sustain a family. I take
- 52:38my whole lab to Boston,
- 52:39to New York, to Philadelphia,
- 52:40and NIH at least twice
- 52:42a year. My whole lab,
- 52:43I just put them in
- 52:44an Airbnb that I can
- 52:45let them talk to these
- 52:46collaborators,
- 52:47like, participate in NIH meetings
- 52:49that they have actually affordable
- 52:50living. I also have affordable
- 52:52living. So doing science and
- 52:53and enjoy life is actually
- 52:55pretty good here. It's quite
- 52:57unique.
- 52:58Yeah. And I would add
- 52:59too. One thing I've really
- 53:00liked about,
- 53:02living here is just how
- 53:03many different options there are.
- 53:04So even just among this
- 53:06panel, I think each of
- 53:07us lives in different areas,
- 53:11in the New Haven area.
- 53:13So there's some faculty who,
- 53:15like Hesper said, live right
- 53:16downtown,
- 53:17like to work,
- 53:19walk to restaurants, everything like
- 53:21that.
- 53:22And I live about twenty
- 53:24minutes outside of New Haven
- 53:26in a smaller town,
- 53:28near the beach and love
- 53:30that. There's other other faculty
- 53:32who live a bit to
- 53:33the north, you know, where
- 53:34there's more, like, forests and
- 53:36hiking trails and things like
- 53:37that. So, really, you have
- 53:39your choice in terms of,
- 53:42like, what kind of living
- 53:44environment you you want,
- 53:47when you when you're here
- 53:49in in New Haven.
- 53:52There's a bunch of questions
- 53:54about,
- 53:55preprints and bioRxiv.
- 53:58Maybe to summarize them,
- 54:01I think they in general
- 54:03are asking,
- 54:04you know, whether preprints can
- 54:05be included in an application,
- 54:08and how they,
- 54:10relate to peer reviewed publications.
- 54:14Anybody wanna take that one?
- 54:18I mean, I would highly
- 54:19encourage it. I think preprints,
- 54:21I I are great. I
- 54:23mean, at least, you know,
- 54:24that's my view, and,
- 54:26and I certainly would encourage
- 54:27it as part of an
- 54:28application. I think it really
- 54:29shows that you have a
- 54:30finished product,
- 54:32that has, hopefully been submitted
- 54:34to a journal,
- 54:35and I think it gives
- 54:36a lot of value to
- 54:37an application.
- 54:39You know, I will say
- 54:39that,
- 54:41you know, when I
- 54:43came here, when I got
- 54:44this job, I actually didn't
- 54:45have
- 54:45my postdoc paper completely published
- 54:48yet. And one of the
- 54:49things that really attracted me
- 54:51to this department was that
- 54:52they were reliant on their
- 54:54own estimation
- 54:55of my work and not
- 54:56the estimation of a journal
- 54:58editor.
- 54:59And that really,
- 55:00you know, was a huge
- 55:02positive in my,
- 55:04in my book. I think,
- 55:05you know,
- 55:06my colleagues want,
- 55:08you know, accepting and and
- 55:09understanding how that my work
- 55:11was exciting,
- 55:13you know, to them was
- 55:13was, yeah, just really valuable
- 55:15and really showed that they
- 55:17have their own minds,
- 55:19and are, using them. So
- 55:25Right.
- 55:26Well said, Hesper.
- 55:29Yes.
- 55:33Okay.
- 55:34Well, we're kind of coming
- 55:36to the end. I I
- 55:38know that I haven't
- 55:40covered everything. Oh, maybe I'll
- 55:42grab one more question here
- 55:44about,
- 55:45the tenure
- 55:46process and tenure timelines.
- 55:50And, you know, briefly, maybe
- 55:52I'll start and you guys
- 55:53can chime in.
- 55:55The appointment again is at
- 55:56the assistant professor level.
- 55:59There is,
- 56:00an initial review at the
- 56:02three year point,
- 56:04and then a second review,
- 56:06which is typically,
- 56:09approximately
- 56:11three years after that,
- 56:13for the promotion to associate
- 56:15professor on term. So that
- 56:16is
- 56:17not a tenure,
- 56:19promotion, but it's a promotion
- 56:20to associate professor. The tenure
- 56:22promotion follows,
- 56:24next, to the level of
- 56:26associate professor with tenure,
- 56:29and and then the professor
- 56:30appointment is is after that.
- 56:32So typically,
- 56:34the maximum
- 56:35combined amount of time for
- 56:37the assistant and associate
- 56:39on term
- 56:40length is ten years.
- 56:43Although again, there can be
- 56:44lots of individual circumstances there.
- 56:47I think the important thing
- 56:48to say is you're not
- 56:49on your own in navigating
- 56:50the tenure process. It's something
- 56:52that I talk with junior
- 56:53faculty about,
- 56:54quite a bit
- 56:56along the way as well
- 56:57as their mentoring
- 56:58committee.
- 57:00And,
- 57:02yeah, the goal is to
- 57:03provide that guidance and experience
- 57:05so that it's something that
- 57:07is consistent with your overall
- 57:09goals as a scientist.
- 57:10It is not, something that,
- 57:14we kind of work on
- 57:15separately from
- 57:16generally
- 57:17having a successful and exciting
- 57:19research program.
- 57:22Other comments about the tenure
- 57:24process?
- 57:26When when I
- 57:28was considering coming here, having
- 57:30been at another institution for
- 57:31two years,
- 57:33the comment I received at
- 57:34my other institution was, why
- 57:35would you wanna go to
- 57:36Yale? You're you're gonna get
- 57:37tenure here in three years.
- 57:40You know, you may not
- 57:40even get tenure there.
- 57:42And my response to that
- 57:44was always, well, if I
- 57:45can't get tenure, I have
- 57:47bigger problems
- 57:48because my career has not
- 57:50gone as I envisioned it.
- 57:51So you know? And I
- 57:53think that holds true here.
- 57:56We we strive
- 57:59to select people that we're
- 58:00confident will get tenure because
- 58:02they're great scientists. They have
- 58:04a great vision for their
- 58:05future,
- 58:06and and we wanna do
- 58:07everything we can to help
- 58:09them,
- 58:10you know, fulfill that vision.
- 58:12And tenure is gonna happen
- 58:14as a consequence. It's it's
- 58:15not something you're you're
- 58:17you should really worry about.
- 58:18And,
- 58:20you know, some people argue
- 58:21that our clock is too
- 58:22long.
- 58:24You know, it can be
- 58:24as short as you want.
- 58:27Right?
- 58:28But it also gives you
- 58:30the
- 58:31the
- 58:32margin
- 58:33to really develop new projects
- 58:35and to do science that
- 58:37you really want to do
- 58:39and fulfill your vision
- 58:41rather than be rushed into
- 58:42getting, you know,
- 58:44x number of papers in
- 58:46five and a half to
- 58:46six years
- 58:48because that's what you need
- 58:49to meet the the the
- 58:51requirements for university
- 58:53x's tenure decision. Right? We
- 58:55we really want you to
- 58:56develop
- 58:57as an independent science,
- 58:59fulfill your scientific vision,
- 59:01and
- 59:03a consequence of that will
- 59:04be you get tenure. No
- 59:05big deal.
- 59:08Great.
- 59:10There's one maybe this will
- 59:11be the last question I
- 59:12cover here,
- 59:14about
- 59:14support,
- 59:16for partners,
- 59:17getting a job, in the
- 59:18New Haven area if you
- 59:20apply.
- 59:21That is something,
- 59:23what I think you'll see
- 59:25when,
- 59:26like, for example, at the
- 59:27interview stage is that we
- 59:29we actually don't ask,
- 59:31about,
- 59:32you know, partners at that
- 59:34point because
- 59:35the the recruitment is really
- 59:37focused on you as a
- 59:38scientist, and that's not a
- 59:40factor that,
- 59:41we use to,
- 59:44you know,
- 59:46prioritize certain people over others.
- 59:48That said, after the offer
- 59:50is made, I do jump
- 59:51in with both feet in
- 59:52finding
- 59:53opportunities for partners, and that's
- 59:55involved,
- 59:56both working across the university,
- 59:59not just the school of
- 60:00medicine, but also other,
- 01:00:02the undergraduate campus all across
- 01:00:04the university,
- 01:00:05working with local biotech, for
- 01:00:07example,
- 01:00:09to find opportunities
- 01:00:11for, partners. So,
- 01:00:13it is again, it is
- 01:00:14not a it's not a,
- 01:00:16you know, something that will
- 01:00:17penalize your application if your
- 01:00:20partner has specific job requirements.
- 01:00:22We will only,
- 01:00:25start working on that after
- 01:00:26we,
- 01:00:27extend an offer, But then
- 01:00:29once we get to that
- 01:00:30point, it is something we,
- 01:00:31work work hard on.
- 01:00:34So with that, we've hit
- 01:00:35one o'clock. Thank you all
- 01:00:37for the really good questions,
- 01:00:39and,
- 01:00:41I hope that this was
- 01:00:43was helpful.
- 01:00:44Thank you to the panelists,
- 01:00:45for your really good answers,
- 01:00:48and again, if there are
- 01:00:49questions that that I didn't
- 01:00:51get to or misinterpreted,
- 01:00:53just email me. I'm happy
- 01:00:55to,
- 01:00:56follow-up
- 01:00:57more.
- 01:00:59Again, I strongly encourage you
- 01:01:00to apply and look forward
- 01:01:01to seeing all your applications,
- 01:01:05fairly soon.
- 01:01:06Okay. Bye, everyone. Take care.