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MPATH Faculty Search Webinar

September 25, 2024
ID
12112

Transcript

  • 00:08Alright.
  • 00:10Hello, everyone. I think, you
  • 00:12are
  • 00:13now being brought into our
  • 00:15webinar.
  • 00:16My name is Andy Goodman.
  • 00:17I'm the director of the
  • 00:19the chair of department of
  • 00:20microbial pathogenesis and director of
  • 00:22the microbial sciences institute at
  • 00:24Yale School of Medicine.
  • 00:25And,
  • 00:27I'm gonna,
  • 00:28use this time, to tell
  • 00:30you a little bit about,
  • 00:31the department, but really wanna
  • 00:33have most of our time,
  • 00:35to answer your your questions
  • 00:37about the faculty search,
  • 00:40about the position, about life
  • 00:42in Connecticut,
  • 00:43and anything else you may
  • 00:44have have questions about.
  • 00:47So I have a fantastic
  • 00:49group of panelists here with
  • 00:51me, and so maybe we'll
  • 00:52start, with with introductions,
  • 00:55from from them. Hesper, why
  • 00:57don't you why don't you
  • 00:58go first?
  • 00:59Hi. My name is Hesper
  • 01:01Rigo, and I'm an associate
  • 01:03professor here in the department.
  • 01:04My lab studies
  • 01:06mycobacterial,
  • 01:08pathogens at the level of
  • 01:09single cells.
  • 01:11And
  • 01:12Yachi?
  • 01:14Hi. My name is Yachi
  • 01:15Ho. I'm associate professor also
  • 01:16here at Microbial Pathogenesis.
  • 01:19I work on mechanisms of
  • 01:20HIV latency
  • 01:22and some single cell genomics
  • 01:23approaches.
  • 01:25Great. And Craig.
  • 01:28Hi. I'm Craig Roy. I'm
  • 01:29a professor of microbial pathogenesis
  • 01:31and immunobiology.
  • 01:33I also serve as the
  • 01:34director of the EOBBS graduate
  • 01:37program, which is the large
  • 01:38umbrella program that micro students
  • 01:40enter through. So I'm happy
  • 01:42to answer any questions you
  • 01:43might have about the graduate
  • 01:44program as well.
  • 01:46And my lab studies, intracellular
  • 01:48bacterial pathogens and how they
  • 01:49manipulate the host.
  • 01:52Great. Thank you.
  • 01:54So,
  • 01:54just briefly about about,
  • 01:57the department of microbial
  • 01:59pathogenesis.
  • 02:01It was,
  • 02:02founded over, twenty years ago
  • 02:03initially as a section
  • 02:05within the school of medicine
  • 02:07and became a department,
  • 02:09about ten years ago.
  • 02:11There are currently,
  • 02:13approximately ten,
  • 02:14primary faculty,
  • 02:16in addition to secondary faculty
  • 02:17in the department,
  • 02:20and they're primarily located in
  • 02:22the Boyer Center at Yale
  • 02:23School of Medicine, although there
  • 02:24are some faculty who are
  • 02:25at, West Campus.
  • 02:29The,
  • 02:30we're in the beginning of
  • 02:31what I think is gonna
  • 02:32be an exciting growth phase
  • 02:33in the department.
  • 02:35This is the second of
  • 02:36what will be a series
  • 02:37of of,
  • 02:39faculty searches,
  • 02:40that we've had, and and
  • 02:42we're very excited that our,
  • 02:44candidate last year recently accepted,
  • 02:47her offer to come,
  • 02:49join us in the department.
  • 02:52In terms of the the
  • 02:53faculty search, this is an
  • 02:55open search,
  • 02:56really open to all areas
  • 02:58of
  • 03:00microbial pathogenesis.
  • 03:02We are interested in candidates
  • 03:04focused on virology,
  • 03:06parasitology,
  • 03:06fungal biology, bacteria,
  • 03:09who are using a wide
  • 03:10range of approaches.
  • 03:13The,
  • 03:14applications
  • 03:15are all through Interfolio.
  • 03:16And if you have any
  • 03:17questions about that process,
  • 03:19I'm happy to to answer
  • 03:20it.
  • 03:22I can say briefly
  • 03:24the way I think about
  • 03:25about,
  • 03:27recruiting,
  • 03:28junior faculty is really through
  • 03:29the lens of of two
  • 03:30questions.
  • 03:32The first is,
  • 03:33how can we as a
  • 03:34department
  • 03:35help somebody
  • 03:37do even better than they
  • 03:38would otherwise?
  • 03:39So we think a lot
  • 03:40about,
  • 03:41ways in which the support
  • 03:43and mentorship and colleagues that,
  • 03:45a candidate would have in,
  • 03:47the Department of Microbial Pathogenesis
  • 03:50could, allow them to do
  • 03:52things even beyond
  • 03:54what they would do do
  • 03:55otherwise.
  • 03:56And then the second question
  • 03:58is, how would we as
  • 03:59a department benefit from bringing
  • 04:00on this new expertise? And
  • 04:02so we're very interested in
  • 04:03people who are thinking about
  • 04:05things differently than the way
  • 04:06we do,
  • 04:08bringing in new approaches,
  • 04:10new model systems, new organisms,
  • 04:13etcetera.
  • 04:15And,
  • 04:16again, we really encourage you
  • 04:18to apply. We've tried to
  • 04:19make, the application,
  • 04:21not too burdensome,
  • 04:23and, again, are happy to
  • 04:25answer,
  • 04:26any of your questions about
  • 04:28about, again, about the application
  • 04:29process, about the position,
  • 04:33the department,
  • 04:34and the school of medicine
  • 04:35and Yale in general.
  • 04:37So the way to ask
  • 04:39questions is actually to, just
  • 04:41type them into the chat.
  • 04:43That'll be visible only to
  • 04:45the panel. So, again, we're
  • 04:46keeping everything anonymous at this
  • 04:48at this stage.
  • 04:50So just type any questions
  • 04:52you have in the chat,
  • 04:54and then what I'll do
  • 04:55is I'll look at them
  • 04:56and
  • 04:59make sure that that, there
  • 05:01aren't redundant questions, then I'll
  • 05:03read them back without your
  • 05:04name,
  • 05:05to,
  • 05:06the audience, and then I'll
  • 05:07ask, the panel to help
  • 05:09with, providing their perspectives.
  • 05:13So, yeah, look, go to
  • 05:15the chat, start putting in
  • 05:17in your questions. And while
  • 05:18you're thinking about that, I'll
  • 05:20just say one more thing,
  • 05:22about the the momentum in
  • 05:24microbiology
  • 05:25here at Yale. You may
  • 05:26have noticed that actually we
  • 05:28have
  • 05:28three faculty searches now open
  • 05:31in microbiology.
  • 05:32The one we're focused on
  • 05:34today is,
  • 05:36the search in the department
  • 05:38of microbial pathogenesis.
  • 05:40There are also two other
  • 05:41searches in affiliation with the
  • 05:42Microbial Sciences Institute, which is
  • 05:45located at Yale's West Campus,
  • 05:47and those are in partnership
  • 05:48with the Department of Immunobiology
  • 05:50and with the Department of
  • 05:51Bioinformatics
  • 05:52and Data Science.
  • 05:53So those searches are separate.
  • 05:55They have separate deadlines, separate
  • 05:57review committees,
  • 06:00and and I,
  • 06:02so if you have questions
  • 06:03about all these different searches,
  • 06:05I'm also happy to, talk
  • 06:06about that as well.
  • 06:09So with that, I will,
  • 06:12just start looking at the
  • 06:13chat, and,
  • 06:15please type in, any questions.
  • 06:17Doesn't matter how simple,
  • 06:19or how,
  • 06:21complicated they are. If you
  • 06:22have the question, I think,
  • 06:24most likely other people do
  • 06:25as well.
  • 06:26I think here we won't
  • 06:28focus on
  • 06:30specific research programs.
  • 06:33If your research program generally
  • 06:35falls under the areas that
  • 06:36are described in the ad,
  • 06:38I would encourage you to
  • 06:39apply,
  • 06:40and I'm also happy to
  • 06:43correspond with you by email
  • 06:44if you have questions about
  • 06:45your specific
  • 06:47research program.
  • 06:48Although I would add that,
  • 06:49you know, the the, application
  • 06:51is going to be evaluated
  • 06:52by a by a committee,
  • 06:54a search committee, and
  • 06:56I wouldn't
  • 06:58really interfere or get in
  • 06:59front of their of their
  • 07:01process.
  • 07:03So
  • 07:04yes, so please type your
  • 07:05questions in the chat
  • 07:08and maybe while we're waiting,
  • 07:11panelists, if you have anything
  • 07:12to add about,
  • 07:14you know, one thing we
  • 07:15could start with is is
  • 07:16maybe your experience,
  • 07:19starting your lab and coming
  • 07:20to Yale,
  • 07:22and,
  • 07:23you know, what you can
  • 07:24share about that.
  • 07:28Craig, I don't know. To
  • 07:30I can I can start
  • 07:31a little bit? Been a
  • 07:32long time for me, so
  • 07:33I don't know if I'm
  • 07:33the best person to speak.
  • 07:36Yeah. Yachi, go ahead.
  • 07:38Yeah. So I started here
  • 07:39twenty seventeen. I would say
  • 07:41this is a wonderful program.
  • 07:42To tell the truth, before
  • 07:44I came for this interview,
  • 07:46I did not know anyone
  • 07:47in this department. And this
  • 07:48is a microbial pathogenesis department
  • 07:51working on very solid side
  • 07:52in molecular biology, microbial hosting
  • 07:55interactions.
  • 07:56I work on HIV and
  • 07:57clinical samples. So when I
  • 07:59applied, I really didn't know
  • 08:00whether I got a chance
  • 08:01or not. And I don't
  • 08:02know. It's just very different
  • 08:03approaches, and I just came.
  • 08:05And then after I came,
  • 08:06I figured out that people
  • 08:07are doing very diverse things
  • 08:09and every everyone in science
  • 08:10is solid and people are
  • 08:11nice and wonderful. So at
  • 08:13that time, I talked to
  • 08:14my chair saying, oh, what
  • 08:15what should I bring here?
  • 08:16What do you want me
  • 08:17to do? And back then,
  • 08:18doctor Jorge Galan said, you
  • 08:20know, just do the best
  • 08:21science. So I've been enjoying
  • 08:23that and my very great
  • 08:24scientific journey. There are wonderful
  • 08:26people here, very, very solid
  • 08:27course such as the genomics
  • 08:29and microscope
  • 08:30and many others and many
  • 08:31other wonderful colleagues here at
  • 08:33Yale. So I really enjoyed
  • 08:34this, and I will feel
  • 08:35that there's no
  • 08:37specific pathogen or approach or
  • 08:38anything.
  • 08:39I I I would hope
  • 08:40to have, you know, anyone
  • 08:42having,
  • 08:43some great science and fun
  • 08:44stories to to join us.
  • 08:49Esper, anything to add?
  • 08:51Yeah. My my experience was
  • 08:52very similar to Yachi. I
  • 08:54started just slightly before
  • 08:56she did. And,
  • 08:58you know, one of the
  • 08:59main reasons why I wanted
  • 09:00to come to this department
  • 09:01is that they were working
  • 09:02on questions that I I
  • 09:03found fascinating, and that was
  • 09:05the direction that I wanted
  • 09:06my lab to move it
  • 09:07move to. You know, specifically,
  • 09:09for me, it was really
  • 09:10about host pathogen interactions. And
  • 09:12to be able to come
  • 09:13to a place that has,
  • 09:14you know, done so much
  • 09:15seminal work in that area
  • 09:16was really,
  • 09:18you know, really exactly where
  • 09:19I wanted to land.
  • 09:21So for me, it was
  • 09:22it was really great to
  • 09:23to start a lab here,
  • 09:25and happy to, yeah, answer
  • 09:27any questions related to that
  • 09:28as well.
  • 09:30Great.
  • 09:31So our first few questions
  • 09:32have started to, come in,
  • 09:35and I may not do
  • 09:36them exactly in order, but
  • 09:38I will try to cover,
  • 09:39everything.
  • 09:41So,
  • 09:42I'll start with,
  • 09:44we one question is,
  • 09:47is there a specific career
  • 09:49stage that the department is
  • 09:50focused on? So this search
  • 09:53is focused on the assistant
  • 09:54professor career stage,
  • 09:57and
  • 09:58and,
  • 10:00this would be someone who,
  • 10:02you know, in most cases
  • 10:03is,
  • 10:05completing their, you know, postdoctoral
  • 10:07studies currently, although they could
  • 10:09be in some other kind
  • 10:10of training stage.
  • 10:11But the search is is,
  • 10:13focused on on,
  • 10:15the assistant professor,
  • 10:18stage.
  • 10:21So the next question
  • 10:27is, whether
  • 10:29ongoing funding is ongoing funding
  • 10:32a critical requirement for the
  • 10:34candidate, or is the perspective
  • 10:36capability of acquiring grants enough?
  • 10:39Anyone
  • 10:40in the panel wanna comment
  • 10:41on that?
  • 10:45I don't think we've
  • 10:46ever,
  • 10:48put a high,
  • 10:53you know,
  • 10:54target or whatever on do
  • 10:56you already have funding.
  • 10:58When when recruiting at the
  • 10:59assistant professor level, we usually
  • 11:01look at the potential for
  • 11:04success,
  • 11:05for synergy with existing members
  • 11:08of the the department,
  • 11:11for value added, new new
  • 11:12approaches, new organisms,
  • 11:14etcetera.
  • 11:17And then,
  • 11:20you know,
  • 11:21we've always had confidence in
  • 11:23the people that we select
  • 11:25will not have problem getting
  • 11:27their funding, and I think
  • 11:28that's mostly panned out. So
  • 11:33So a related question,
  • 11:36was whether it's necessary to
  • 11:38include a budget
  • 11:40information in the statement of
  • 11:41research plan. So I can
  • 11:42add to that. The answer
  • 11:43to that is no.
  • 11:45We're really focused on,
  • 11:48the scientific questions you do
  • 11:50wanna answer, why those questions
  • 11:52are important,
  • 11:53why you're the right person
  • 11:54to answer those questions, and
  • 11:56how we can help,
  • 11:58you reach even further than
  • 11:59you would, otherwise.
  • 12:04There are some,
  • 12:05there's a question about,
  • 12:07interdisciplinary
  • 12:09research.
  • 12:10You know, do we encourage
  • 12:11interdisciplinary
  • 12:12research? The answer to that
  • 12:13is absolutely yes.
  • 12:16You know, many of our
  • 12:17current faculty
  • 12:19are highly interdisciplinary
  • 12:20in the work that they
  • 12:21do.
  • 12:22One thing that I've really
  • 12:23appreciated about,
  • 12:25Yale is that
  • 12:27it is,
  • 12:28a large enough institution that
  • 12:30there are experts in really
  • 12:32anything you could imagine, but
  • 12:33it's also small enough that
  • 12:34it's very easy to collaborate.
  • 12:37It's common for,
  • 12:40for me to get emails
  • 12:41just out of the blue
  • 12:42from other Yale faculty or
  • 12:43their students saying, you you
  • 12:45know, I'm also at Yale.
  • 12:46I'm interested in this or
  • 12:47that about the microbiome, and
  • 12:48could we meet?
  • 12:50And, again, I think that's
  • 12:51part of,
  • 12:52Yale being in this, nice,
  • 12:55sweet spot of size
  • 12:57that,
  • 12:58facilitates those kinds of,
  • 13:00easy collaborations.
  • 13:04And and I I could
  • 13:05just add to that, Anthony,
  • 13:06that, you know, one to
  • 13:08to pitch again the BBS
  • 13:09graduate program, one of the
  • 13:11nice things about this large
  • 13:12umbrella graduate program is we
  • 13:14have students coming in with
  • 13:15many different scientific interests who
  • 13:18cross pollinate and fertilize many
  • 13:19labs in many different departments
  • 13:21bringing in,
  • 13:22new approaches, new ideas.
  • 13:25And in in in many
  • 13:26instances, even if the student
  • 13:28doesn't join your lab,
  • 13:30they become friends with someone
  • 13:32in your lab, and and
  • 13:33lots of collaborations, lots of
  • 13:35ideas,
  • 13:36of an interdisciplinary
  • 13:38nature are formed simply by
  • 13:40the the,
  • 13:41students,
  • 13:43having this opportunity to, you
  • 13:45know, come into this large
  • 13:46umbrella program, meet each other,
  • 13:48learn about what they're doing,
  • 13:49and and interact. So,
  • 13:52the other thing I'd like
  • 13:53to add to that is
  • 13:54that, you know,
  • 13:57I've always found Yale to
  • 13:59be one of the most
  • 13:59highly collaborative places
  • 14:01that I've been, including many
  • 14:03places on the West Coast
  • 14:04and the East Coast,
  • 14:06that shall not be named.
  • 14:07And departmental lines here, although
  • 14:09they're important for administrative
  • 14:11reasons,
  • 14:12they're really not important for
  • 14:13scientific reasons. This is probably
  • 14:15one of the the friendliest
  • 14:17and most
  • 14:19interactive and collaborative places across
  • 14:21disciplines,
  • 14:22that that I've experienced. And
  • 14:24and without,
  • 14:26you know, having great colleagues
  • 14:27in cell biology, great colleagues
  • 14:29in immunobiology,
  • 14:30great colleagues in structural biology,
  • 14:33I don't think we'd we
  • 14:35would have ever been able
  • 14:36to have the success that
  • 14:37we've been able to achieve
  • 14:39at at most other places.
  • 14:42Craig, maybe this is a
  • 14:43good chance for you to,
  • 14:44just say a little bit
  • 14:45about the BBS program and,
  • 14:47you know, every school is
  • 14:48different and maybe just about
  • 14:50the umbrella versus the graduate
  • 14:52programs and,
  • 14:54how that fits together at
  • 14:55Yale.
  • 14:57Yeah. So so the BBS
  • 14:58graduate program here at Yale
  • 15:00is an umbrella program. So
  • 15:01students enter through,
  • 15:03what we call tracks, which
  • 15:05the tracks themselves
  • 15:07are focused on,
  • 15:09more,
  • 15:11specific scientific areas of investigation,
  • 15:14ranging from immunobiology,
  • 15:16cell biology,
  • 15:18microbiology,
  • 15:19computational biology,
  • 15:20pharmacology, physiology.
  • 15:23And but the students, when
  • 15:25they enter one of these
  • 15:26tracks, they're still part of
  • 15:27the large umbrella program. They're
  • 15:29free to rotate in any
  • 15:30lab they want and join
  • 15:31any lab they want.
  • 15:33So of the sum, you
  • 15:35know, I think we're up
  • 15:35to now four hundred faculty
  • 15:37that make up the BBS
  • 15:38graduate
  • 15:40program. It's it's very common
  • 15:42to get students who,
  • 15:45you know, enter through another
  • 15:46track, and and you as
  • 15:48a faculty member
  • 15:49oftentimes participate in multiple tracks,
  • 15:53and therefore recruit students from
  • 15:55those tracks to be part
  • 15:56of your lab.
  • 15:58So it's really kind of
  • 16:00nice in that the selection
  • 16:02process for students is based
  • 16:03on the tracks, so it
  • 16:05spreads the workload out.
  • 16:07But the students have unlimited
  • 16:09opportunities to to rotate and
  • 16:11join any lab they want.
  • 16:13I would like to add
  • 16:14on. I'm the director for
  • 16:15the microbiology
  • 16:17PC program.
  • 16:18So we have about five
  • 16:19to ten students each year.
  • 16:21They frequently rotate in our
  • 16:23faculty labs, but, also, we
  • 16:25will get, like, students from
  • 16:27other tracks such as iBio
  • 16:28or, computer science and things
  • 16:30like those. What I what
  • 16:31Quake just said is that
  • 16:33all students affiliated with Yale
  • 16:34BBS can choose any PI,
  • 16:36but then Yale is a
  • 16:38is a close community with
  • 16:39the sizes that is not
  • 16:40that huge. So we our
  • 16:42PS do get access to
  • 16:43students, very, very often.
  • 16:48Okay. The next question, I'm
  • 16:50gonna answer part of it
  • 16:51and ask Yachi to answer
  • 16:52the other part.
  • 16:54So the question is, if
  • 16:55someone's involved in clinical research,
  • 16:58is the main campus or
  • 16:59west campus better in terms
  • 17:01of hospital access,
  • 17:02you know, in in light
  • 17:03of the other faculty searches
  • 17:05that are going going on?
  • 17:08So I'll talk about the
  • 17:09west campus and main campus
  • 17:10part, and then, Yachi, maybe
  • 17:11you can talk about,
  • 17:13clinical samples and and and
  • 17:15that kind of thing. So,
  • 17:17in terms of the main
  • 17:18campus and west campus, they're
  • 17:20about five miles apart from
  • 17:22each other.
  • 17:23This position is,
  • 17:25for,
  • 17:26lab space at the medical
  • 17:28school in the Boyer Center
  • 17:29for Molecular Medicine,
  • 17:33And and,
  • 17:35so that's where where the
  • 17:36lab will be.
  • 17:38But in terms of the
  • 17:39appointment
  • 17:40in microbial pathogenesis,
  • 17:44that's really the defining feature
  • 17:46in terms of being a
  • 17:47member of the school of
  • 17:48medicine. So,
  • 17:50the
  • 17:51the,
  • 17:52you know, being a member
  • 17:53of the school of medicine
  • 17:54at the West Campus or
  • 17:55at,
  • 17:57the the main campus, you
  • 17:59would
  • 18:00interface with the same programs
  • 18:02for clinical collaboration either way.
  • 18:05The hospitals indeed are
  • 18:07located at the medical school,
  • 18:09the main campus,
  • 18:12but the interaction is very
  • 18:13close because, again, it's five
  • 18:16miles away. There's shuttles that
  • 18:17run every twenty minutes, and
  • 18:19everybody who's at the West
  • 18:20Campus is a part of,
  • 18:23some department,
  • 18:24at the the, the main
  • 18:26campus.
  • 18:28So maybe, Yachi, you could
  • 18:29talk a little bit about,
  • 18:32clinical samples.
  • 18:33Sure.
  • 18:34I do work on clinical
  • 18:35samples. For example, I get
  • 18:37a blood and it's the
  • 18:38other samples from people having
  • 18:40HIV.
  • 18:41This is like bread and
  • 18:42butter just like
  • 18:43someone would count mouse in
  • 18:44the mouse house. So I
  • 18:45would say their existing IRB
  • 18:47and then their existing access
  • 18:49to these, collaborators in the
  • 18:50clinic. And I there there
  • 18:52has been setting up of
  • 18:53these, like, collaborations for, like,
  • 18:55ten, twenty years, so I
  • 18:56can easily approach these physicians.
  • 18:57They are very happy to
  • 18:59recruit participants. And then I
  • 19:00do need to file ARB,
  • 19:02but there are templates and
  • 19:03the ARB crew would help
  • 19:04us to file those. So
  • 19:05I would say I don't
  • 19:06have any any problems getting
  • 19:08those samples. For example, recently,
  • 19:09we tried to get a
  • 19:11gut biopsy samples from the
  • 19:12hospital. We get it every
  • 19:13week. So, they're still sending
  • 19:15procedures,
  • 19:17a bit to for us
  • 19:18to get access to these
  • 19:19samples.
  • 19:21Right.
  • 19:23Okay. Thank you.
  • 19:26The next question is about,
  • 19:28core facilities
  • 19:30at Yale. So what core
  • 19:31facilities are accessible,
  • 19:33that may be useful for,
  • 19:36research in microbial pathogenesis?
  • 19:41I can take at least
  • 19:42part part of this question.
  • 19:44So I mean, there's lots
  • 19:46of core facilities. The one
  • 19:48a lot,
  • 19:49one that
  • 19:50our lab and I know
  • 19:51others here use is a
  • 19:52flow cytometry core.
  • 19:54That has been really amazing
  • 19:56for us. In fact, when
  • 19:57I first started the lab,
  • 19:58I actually thought about buying
  • 19:59our own flow cytometer,
  • 20:01and, I have been so
  • 20:02happy with the core.
  • 20:04And it's a core that
  • 20:05exists at all sorts of
  • 20:06different biosafety levels all the
  • 20:07way up to BSL three.
  • 20:10And, so we've been very,
  • 20:12very happy with that. There's
  • 20:14microscopy cores all around.
  • 20:16One of the great things
  • 20:17about
  • 20:18Yale is actually that imaging
  • 20:20is, really strong here. So
  • 20:22even if you can't find,
  • 20:23like, a microscope that you
  • 20:24need,
  • 20:25in a core facility,
  • 20:26chances are there might be
  • 20:27one that someone has built
  • 20:29somewhere and, could potentially help
  • 20:31you use.
  • 20:32So we've been very happy
  • 20:34with those core facilities. I
  • 20:35we've also used sequencing core
  • 20:36facilities, and there's actually a
  • 20:39a drug discovery core facility.
  • 20:41There's,
  • 20:42you know,
  • 20:44pretty much if you want
  • 20:45it somewhat, it probably is
  • 20:46here.
  • 20:49I would like to add
  • 20:49on the sequencing facility because
  • 20:51my lab does a lot
  • 20:52of single cell sequencing
  • 20:54and many fancy platforms. I
  • 20:55I would say when I
  • 20:56came here for a second
  • 20:57visit, I talked to the
  • 20:58YCGA director and he said
  • 21:00that basically the dean gave
  • 21:01him ten million dollars to
  • 21:02make the best facility ever,
  • 21:04for to support research use.
  • 21:06And during the COVID time,
  • 21:07for example, people want to
  • 21:08sort, you know, COVID passing
  • 21:10mouse samples and human samples.
  • 21:11How dangerous would that be
  • 21:12in the court? They are
  • 21:13to say, we will make
  • 21:14it happen under the best
  • 21:16spouse safety and support your
  • 21:17research. So, basically, Yale is
  • 21:19a place that when the
  • 21:20dean has extra funding, they
  • 21:21put that into into core
  • 21:23facilities that we have the
  • 21:24best high end, you know,
  • 21:26sequencing facility that sequencing here
  • 21:28is one million reads, is
  • 21:29one dollar. So it's pretty
  • 21:30cheap compared with other institutes.
  • 21:32So I would say there
  • 21:33are many different cores available
  • 21:34that do support the research
  • 21:36program.
  • 21:38And they've also invested heavily
  • 21:40in cryo electron microscopes,
  • 21:41including three Titan Krios as
  • 21:44well as some other really
  • 21:45nice microscopes and
  • 21:47and FIB milling. So, you
  • 21:48know, we're now doing,
  • 21:51high throughput
  • 21:52volume
  • 21:53rendering through cells by by,
  • 21:56cryo EM where we can
  • 21:57get, you know, three d
  • 21:58reconstructions of an entire infected
  • 22:00cell in a matter of
  • 22:02days,
  • 22:03which is something that, you
  • 22:04know,
  • 22:05we tried ten years ago.
  • 22:07It just wasn't possible, and
  • 22:09it's all through the core
  • 22:10facilities and the investments
  • 22:11Yale has made in in
  • 22:14these these cryo EM facilities,
  • 22:16which are just phenomenal right
  • 22:18now.
  • 22:20Thanks.
  • 22:22Another question. And now we
  • 22:23have many questions, so I'm
  • 22:24gonna do my best, to
  • 22:27identify,
  • 22:29go through all of them.
  • 22:31How valuable are computational
  • 22:33skills in this role? Is
  • 22:34there a possibility they have
  • 22:36a purely computational lab in
  • 22:37the department?
  • 22:38Maybe I'll answer that.
  • 22:41There's quite a bit of
  • 22:42of,
  • 22:43computational focus in the department,
  • 22:45including Yachi's lab as as
  • 22:47one example.
  • 22:49And, certainly, that's an example
  • 22:51of an area where, we
  • 22:54would,
  • 22:56again, we're we're looking for
  • 22:57labs that will,
  • 22:59not only that we can
  • 23:00help do better, that will
  • 23:01help us do better. And
  • 23:03so we're definitely open to
  • 23:04people bringing in other techniques.
  • 23:06You know, that said, we
  • 23:08also it's very important to
  • 23:09us that we can provide
  • 23:10the best mentorship,
  • 23:12possible for our junior faculty.
  • 23:15And so I think it
  • 23:16really would come down to
  • 23:17the individual program and,
  • 23:20convincing
  • 23:21ourselves that that,
  • 23:23you know, as a department
  • 23:24of of, microbial pathogenesis that
  • 23:26we can, again, provide the
  • 23:28best mentorship for someone. So
  • 23:30it depends on, I think,
  • 23:31a purely computational lab. It
  • 23:33would depend
  • 23:34on the program and their
  • 23:35goals and what kind of
  • 23:36support they they need to
  • 23:38do their best in terms
  • 23:39of whether that would be
  • 23:40a good match.
  • 23:44The,
  • 23:47there's a question about if
  • 23:48you're potentially,
  • 23:51eligible for more than one
  • 23:52of these searches.
  • 23:54Is it recommended to apply
  • 23:55to both or just one?
  • 23:57Probably better to apply to
  • 23:59both. I mean, we'll be
  • 24:00keeping an eye on all
  • 24:02the searches together and interfacing.
  • 24:04So if there are applications
  • 24:06that come in through one
  • 24:07search and are better suited
  • 24:08for another, we will be
  • 24:10able to,
  • 24:12identify that,
  • 24:13but probably best for you
  • 24:14to apply for the searches
  • 24:16that,
  • 24:17you know, you think you're
  • 24:18eligible and would be a
  • 24:19good match, for you.
  • 24:23Andy, correct me if I'm
  • 24:24wrong, but the current MSI
  • 24:26search isn't
  • 24:27through microbial pathogenesis, meaning that
  • 24:30people applying to that search
  • 24:32will not be appointed
  • 24:35to the department of microbial
  • 24:36pathogenesis.
  • 24:37So they won't be part
  • 24:38of our cohort.
  • 24:40Yes. That's exactly right. It's
  • 24:41a these are separate searches.
  • 24:44I think people who do
  • 24:45us, you know, search on
  • 24:46science careers for microbiology at
  • 24:49Yale, all three of these
  • 24:50will come up, which is
  • 24:51why I wanted to highlight
  • 24:52it. But those other searches
  • 24:53are primary appointments in other
  • 24:55departments.
  • 24:56Again, one in bioinformatics and
  • 24:58data science, the other in
  • 25:00immunobiology.
  • 25:04We there's a question about,
  • 25:07is there a limit on
  • 25:08the number of years after
  • 25:09PhD for the candidate?
  • 25:11And maybe we can kind
  • 25:13of talk more broadly about,
  • 25:16you know, what are the
  • 25:18you know, whether or not
  • 25:19we have limits and rules
  • 25:21in that way in terms
  • 25:22of who could be a
  • 25:24a candidate.
  • 25:25Well Does anyone I I
  • 25:27don't think it's uncommon these
  • 25:28days for people sometimes to
  • 25:30have done two postdocs. Maybe
  • 25:31they wanted to switch areas
  • 25:32of interest
  • 25:34after doing a four year
  • 25:35postdoc or or explore another
  • 25:37area.
  • 25:38So, you know, the clock
  • 25:39will be different for different
  • 25:41people. I don't I don't
  • 25:43think that we've ever, you
  • 25:44know,
  • 25:46looked at someone and said,
  • 25:47oh, they've been in this
  • 25:48position for postdoctoral position for
  • 25:51seven years.
  • 25:52That's too long.
  • 25:53Right?
  • 25:54I think it's, you know,
  • 25:56more a matter of what
  • 25:58questions are you
  • 26:00investigating,
  • 26:02you know, what what's your
  • 26:03potential,
  • 26:05going forward,
  • 26:07and how can we
  • 26:09mesh and and is it
  • 26:11a good fit
  • 26:12synergistically
  • 26:13in the department? I I
  • 26:15I would venture as a
  • 26:17member of a search committee
  • 26:18not to put a lot
  • 26:19of,
  • 26:21stock in kind of number
  • 26:22of years post PhD that
  • 26:25the the applicant has had.
  • 26:27But if anyone feels differently,
  • 26:28please No. I completely I
  • 26:30completely agree.
  • 26:32The the next question is
  • 26:33about teaching. Maybe I'll throw
  • 26:34this one to Hesper.
  • 26:37Wondering about opportunities
  • 26:39for teaching at the graduate
  • 26:42level,
  • 26:43which courses are available,
  • 26:47changes or developing specific courses,
  • 26:49and then also,
  • 26:50teaching at the undergraduate level.
  • 26:53Right. So the position that
  • 26:55we're talking about is at
  • 26:56at the medical school. So
  • 26:57there isn't a formal undergraduate
  • 27:00teaching requirement,
  • 27:02as you know, this is
  • 27:03very much in contrast if
  • 27:04you were to apply to
  • 27:05a department that,
  • 27:07was at sort of the
  • 27:08the main campus
  • 27:10as as at least I
  • 27:11call it.
  • 27:12So this is so because
  • 27:13of that, you know, we
  • 27:14mostly teach graduate students and
  • 27:16our core and our department
  • 27:18administers,
  • 27:20several courses,
  • 27:21in,
  • 27:23in
  • 27:24microbiology. So we run a
  • 27:25course, and I'm one of
  • 27:26the course directors for the
  • 27:28bacterial
  • 27:29bacteriology course,
  • 27:31that's really focused on bacterial
  • 27:32pathogens
  • 27:33and bacterial pathogenesis.
  • 27:35And then we also,
  • 27:37administer a course in virology.
  • 27:40And those courses are very
  • 27:41small. They're very geared towards,
  • 27:43graduate students in their first
  • 27:45and second year. They're, you
  • 27:46know, often about five,
  • 27:49students, and they're very seminar
  • 27:51based.
  • 27:52I will say that I
  • 27:52also,
  • 27:55am involved in teaching in
  • 27:56other ways here. So I
  • 27:57actually helped teach a microscopy
  • 27:59course, through the department of
  • 28:01cell biology. And I I
  • 28:03do a few lectures even
  • 28:04for the undergraduate,
  • 28:06microscopy
  • 28:07course as well. So there's
  • 28:08definitely opportunities,
  • 28:10to be involved in teaching
  • 28:11in all different
  • 28:12levels if that's something you're
  • 28:14you're interested in. But it's
  • 28:16certainly not a especially
  • 28:17at the at the,
  • 28:19undergraduate level, it's not a
  • 28:20primary focus of of, what
  • 28:23we do. That being said,
  • 28:24of course, you know, you're
  • 28:25teaching your graduate students in
  • 28:26your lab and that's really,
  • 28:27you know, at least how
  • 28:28I view it, that's a
  • 28:29primary source of, a mentorship
  • 28:31and teaching,
  • 28:32for for, you know, this
  • 28:34type of position.
  • 28:36Right. One thing that I
  • 28:37really liked when when I
  • 28:38came here having spent two
  • 28:40years at another medical school
  • 28:41for my first two years
  • 28:42as a
  • 28:43assistant professor is we weren't
  • 28:45responsible for teaching the medical
  • 28:47students medical microbiology.
  • 28:49That's all done by the
  • 28:50clinical departments. We don't have
  • 28:51to teach any of the
  • 28:52the medical students,
  • 28:55which I like.
  • 28:59I would like to clarify
  • 29:01that these academic jobs, some
  • 29:02are more teaching focused, such
  • 29:03as, like, seventy five percent
  • 29:04teaching,
  • 29:05sponsored, kind of responsibilities, but
  • 29:07our department are, mostly mostly
  • 29:09research focused. So I teach
  • 29:11no more than five classes,
  • 29:13three to five class. It's
  • 29:14like a three to five
  • 29:15hours
  • 29:16a year. So we are
  • 29:17focusing on research.
  • 29:20Yep. I mean, we we
  • 29:22continually evolve these courses, and
  • 29:24so there's always opportunities to
  • 29:26bring in new areas.
  • 29:28I did that when I
  • 29:29was course director. Hesper's done
  • 29:30that quite a bit now
  • 29:32as as course director.
  • 29:34So there is opportunity are
  • 29:35opportunities to,
  • 29:37expand our teaching. But like
  • 29:39Yachi said,
  • 29:41the typical
  • 29:42teaching contribution
  • 29:44is,
  • 29:45you know, maybe one or
  • 29:46two lectures per semester,
  • 29:49in a in a small
  • 29:50group format.
  • 29:53Good. So I think I
  • 29:54mean, there are there's been
  • 29:55many questions on the chat
  • 29:56about teaching. Hopefully, that covered,
  • 29:58the gist of it, and
  • 29:59you're welcome to email me
  • 30:01if your question wasn't wasn't
  • 30:02answered,
  • 30:04as well.
  • 30:15So there's a question about
  • 30:18kind of about fit on
  • 30:20the topic
  • 30:22and
  • 30:24getting a sense for for
  • 30:25students
  • 30:27and
  • 30:28publications
  • 30:29from PhD students before graduating.
  • 30:31So maybe the first one
  • 30:32is is what kind of
  • 30:34conferences
  • 30:34do our students typically go
  • 30:37to?
  • 30:41Anyone wanna share about that?
  • 30:46You know, large society
  • 30:48meetings, you know, the ASM
  • 30:50general meeting,
  • 30:52you know, there's a big,
  • 30:54I know, virology meeting. A
  • 30:55lot of the virology students
  • 30:56go to each year.
  • 30:58The Cold Spring Harbor meetings.
  • 31:00Cold Spring Harbor is very
  • 31:01accessible to here, so a
  • 31:02lot of people go to,
  • 31:04meetings at Cold Spring Harbor
  • 31:06that are related to their,
  • 31:08field of study.
  • 31:10The Gordon Research Conferences are
  • 31:12are a very popular
  • 31:14series and and very diverse,
  • 31:16so there's always subject areas
  • 31:18that,
  • 31:20you know, are within the
  • 31:22scope of what we do
  • 31:22here in the Gordon Research
  • 31:24Conferences,
  • 31:26as well as, you know,
  • 31:27smaller workshops and and international
  • 31:30meetings.
  • 31:32I think our students are
  • 31:34well represented at at a
  • 31:35lot of these meetings and
  • 31:36and are often selected,
  • 31:39as, you know,
  • 31:40speakers for ten minute talks.
  • 31:45Thank you.
  • 31:46We have a question.
  • 31:47I'm not sure how well
  • 31:48we can answer this, but
  • 31:49someone asked about the competitiveness
  • 31:52for this application.
  • 31:54I think what I can
  • 31:55say there is,
  • 31:57that,
  • 31:59we
  • 32:00well, first thing I can
  • 32:01say is that we do
  • 32:03have the possibility of offering
  • 32:04multiple,
  • 32:06positions,
  • 32:08and that will again depend
  • 32:09on on the applications we
  • 32:10get.
  • 32:11So there there, again, there
  • 32:13may be more than one
  • 32:14even within this microbial pathogenesis
  • 32:16search, there may be the
  • 32:17possibility of of offering more
  • 32:19than one person
  • 32:22a job offer.
  • 32:24Every application will be read
  • 32:26by multiple members of,
  • 32:29of the search committee as
  • 32:30well.
  • 32:31And oftentimes,
  • 32:33when we do this initial
  • 32:35review,
  • 32:36if there's any applications where
  • 32:39even if one committee member,
  • 32:42was was less enthusiastic, if
  • 32:44there's a split score,
  • 32:45we'll take the time as
  • 32:47a group to discuss the
  • 32:48application, together.
  • 32:50So your application will be
  • 32:51looked at, very carefully, again,
  • 32:53by multiple people,
  • 32:55on the search committee,
  • 32:57and and we also do
  • 32:59have the at least the
  • 33:00possibility of offering multiple,
  • 33:03positions out of this one
  • 33:04search.
  • 33:06The next question,
  • 33:08maybe I'll ask one of
  • 33:09my panelists, maybe multiple
  • 33:11panelists to comment on,
  • 33:13is, talking about resources for
  • 33:16junior faculty support
  • 33:17in terms of career development,
  • 33:20NIH funding, and mentoring.
  • 33:24Maybe I'll kind of start
  • 33:26from my perspective as as
  • 33:27chair, that I I consider,
  • 33:29you know, mentoring junior faculty
  • 33:31to be a main part
  • 33:32of my job.
  • 33:34And when junior faculty come
  • 33:36in, we establish mentoring committees
  • 33:38within the department,
  • 33:40that meet with new faculty
  • 33:42on a regular basis,
  • 33:44to give guidance on all
  • 33:45of the challenges that come
  • 33:46up when you start a
  • 33:47lab anywhere,
  • 33:49including writing grants,
  • 33:52and building your lab.
  • 33:55In addition, there is,
  • 33:57at the school of medicine,
  • 33:59there's,
  • 34:01a cohort of junior faculty
  • 34:03across the school of medicine
  • 34:04that in basic science that
  • 34:06kinda come in around the
  • 34:07same time
  • 34:08and, connect together to talk
  • 34:10with each other about,
  • 34:12challenges and opportunities in starting
  • 34:14a new lab. So there's
  • 34:16both peer mentoring as well
  • 34:17as faculty mentoring,
  • 34:19going on in in the
  • 34:20department.
  • 34:21I often read,
  • 34:23grant applications
  • 34:24from junior faculty
  • 34:26as well to provide a
  • 34:27perspective and and guidance.
  • 34:30And then we also have
  • 34:32what we call faculty research
  • 34:33in progress,
  • 34:35talks
  • 34:35within the department. These are
  • 34:37faculty only,
  • 34:38and it's time where everyone
  • 34:40in all the faculty in
  • 34:41the department are really focused
  • 34:43on your research and using
  • 34:44their experience,
  • 34:46on study section and writing
  • 34:47grants themselves to provide guidance,
  • 34:50and that can be a
  • 34:51very helpful way also for
  • 34:52getting support on these kinds
  • 34:54of things.
  • 34:56Other panelists wanna comment on,
  • 34:59resources
  • 35:00and practices at Yale?
  • 35:02I'd just like to point
  • 35:03out, Andy, that we have
  • 35:04a mandatory requirement
  • 35:06for all
  • 35:08PIs, including existing PIs if
  • 35:10they haven't taken the the
  • 35:12mentoring
  • 35:13workshop,
  • 35:14that they must now complete,
  • 35:17a Yale
  • 35:18sponsored mentoring workshop, which I
  • 35:20think there's something like eight
  • 35:22sessions over a semester,
  • 35:25that was developed by the
  • 35:27National
  • 35:28Mentoring Research Network.
  • 35:30And our our,
  • 35:33instructors in this have been
  • 35:34been trained through the this
  • 35:36organization.
  • 35:38So all of the all
  • 35:40of the PIs
  • 35:41have to complete this mentoring,
  • 35:44workshop,
  • 35:45in order to take PhD
  • 35:46graduate students.
  • 35:49And
  • 35:50it's offered free of charge.
  • 35:51And and
  • 35:53on a on a semester
  • 35:54each semester, we offer it
  • 35:56to the new investigator. So
  • 35:59you do get you do
  • 36:00get,
  • 36:02mentoring on being a mentor.
  • 36:07Other comments?
  • 36:10Yeah. The I think that
  • 36:11all those things sort of
  • 36:12cover it.
  • 36:14You know, I when I
  • 36:15was very first started, I,
  • 36:17actually, Yale paid for me
  • 36:19to go to
  • 36:20a two day intensive mentoring
  • 36:24workshop,
  • 36:24that was overnight in a
  • 36:26nearby town called Old Saybrook.
  • 36:28And, you know, I still
  • 36:29rely on the lessons that
  • 36:31I learned from that. And,
  • 36:33this is one of the
  • 36:33things that, you know, when
  • 36:34you're first beginning, you don't
  • 36:36you don't really know how
  • 36:37to manage, and you're really
  • 36:38you know, I think it's
  • 36:39a big challenge, and I
  • 36:40think that Yale,
  • 36:42acknowledges that it's a challenge
  • 36:43and and really works to
  • 36:44to help you out as
  • 36:45an assistant
  • 36:47professor. I and in terms
  • 36:48of getting funding, you know,
  • 36:49I,
  • 36:51you know, I sat in
  • 36:52in Jorge Galan's office for
  • 36:54many many times with my
  • 36:55r o one sort of
  • 36:56splayed open, and, you know,
  • 36:58we really went into it,
  • 37:00and really and
  • 37:02enormous, very detailed,
  • 37:04you know, discussions, and it
  • 37:06was,
  • 37:07incredibly helpful. And, you know,
  • 37:09I it was really through
  • 37:10those discussions that I was
  • 37:11able to to get my
  • 37:12first r o one. So,
  • 37:14I think the the, you
  • 37:15know,
  • 37:17the desire and the ability
  • 37:18here is to help,
  • 37:20new professors,
  • 37:22you know, get the things
  • 37:22that they need to succeed.
  • 37:25I'll add on to that.
  • 37:26You know, when I just
  • 37:27came, I have this feeling
  • 37:29that, at that time, it
  • 37:30was doctor Jorge Golang as
  • 37:31the chair. What the feeling
  • 37:33he gave me is that
  • 37:34if I'm not able to
  • 37:35tenure, he will feel very,
  • 37:36very sorry. So this is
  • 37:37a department that in the
  • 37:39very first year, he will
  • 37:40keep asking me, actually, do
  • 37:41you need this? Do you
  • 37:42need that? I can do
  • 37:43this. Do you want this?
  • 37:44Do you want that? This
  • 37:45is a department that you're
  • 37:47trying all the best to
  • 37:48support us to to grow,
  • 37:49and I really enjoy this.
  • 37:50And second, for the faculty
  • 37:52faculty mentoring committee, you are
  • 37:54not assigned with someone. You
  • 37:55find someone, which I found.
  • 37:57For example, I found an
  • 37:58HIV person and and actually
  • 37:59doctor Craig Roy works on
  • 38:01having nothing to do with
  • 38:02HIV, but he gave me
  • 38:04such, wonderful
  • 38:05advice career advices that I'm
  • 38:07still talking to him, like,
  • 38:08like, every week and very
  • 38:09frequently.
  • 38:10And I also reach out
  • 38:11to other faculties at Yale
  • 38:12such as doctor Joe Craft,
  • 38:13Immuno Biology. There's no limit.
  • 38:15And people are all very
  • 38:17willing to help, and I
  • 38:18really enjoy, like, working with
  • 38:20me.
  • 38:22We have a question,
  • 38:25about,
  • 38:26whether it's possible to submit
  • 38:27more than three letters of
  • 38:29reference.
  • 38:30I think the form is
  • 38:34is set for only three.
  • 38:37And depending on the situation,
  • 38:39you know, one
  • 38:41one path there is to
  • 38:42just select the three who
  • 38:43would best be able to
  • 38:44comment on you and your
  • 38:46work.
  • 38:47If the advisers like, in
  • 38:49the case of multiple postdoc
  • 38:51advisers,
  • 38:52if they
  • 38:53are if the project is
  • 38:54collaborative and one of them
  • 38:56can write
  • 38:58on behalf of both of
  • 38:59them, that's another
  • 39:00possibility.
  • 39:02If there's truly no way
  • 39:03to identify which three can
  • 39:05best represent
  • 39:07your,
  • 39:09your work, and it's not
  • 39:11possible to have one of
  • 39:12them
  • 39:14integrate comments from more than
  • 39:15one person, send me an
  • 39:16email, and we'll figure out
  • 39:17what to do there.
  • 39:23Now we have lots of
  • 39:24questions, so thank you. If
  • 39:26I don't get to your
  • 39:26question, please follow-up by email.
  • 39:33Let's see.
  • 39:34So,
  • 39:36there's a question about
  • 39:39funding opportunities,
  • 39:40institutional
  • 39:41or departmental funding opportunities available
  • 39:43for
  • 39:44new junior faculty.
  • 39:47So we could maybe talk
  • 39:48about the process, the internal
  • 39:50grant process,
  • 39:52for those,
  • 39:53grant programs that the university
  • 39:55can only put in one
  • 39:56or two nominations.
  • 39:59Anyone wanna talk about about
  • 40:00that?
  • 40:02Sure. So yeah. So in
  • 40:03your first few years, there's
  • 40:05you're gonna get a lot
  • 40:06of emails about
  • 40:07different junior faculty
  • 40:09awards,
  • 40:10many of which can only
  • 40:11have one,
  • 40:13person submitted from Yale. And
  • 40:15so there's actually an internal
  • 40:16Yale committee
  • 40:17that reads applications from all
  • 40:19over Yale and then selects
  • 40:20one,
  • 40:22maybe two, depending on the
  • 40:23the foundation,
  • 40:25to then go and compete
  • 40:26nationally.
  • 40:27So it's these are very,
  • 40:30you know, very simple applications.
  • 40:32Often, they're, like, two pages,
  • 40:34and,
  • 40:35and our department, I think,
  • 40:37has had a pretty good
  • 40:38history of actually getting,
  • 40:40quite a few of those.
  • 40:42Yeah. So and then there's
  • 40:43yeah. I I think that
  • 40:45that pretty much covers it.
  • 40:46There's other there's actually some
  • 40:47internal funding for postdocs and
  • 40:49things like that that actually
  • 40:50is a,
  • 40:51new faculty,
  • 40:52is quite helpful.
  • 40:58And, you know, in addition,
  • 40:59in terms of internal funding,
  • 41:01the
  • 41:02you know,
  • 41:03our goal is really to
  • 41:04set up junior faculty to
  • 41:06be successful.
  • 41:08When we provide a start
  • 41:09up package, we think about,
  • 41:12what the candidate's goals are
  • 41:14in terms of developing their
  • 41:15lab,
  • 41:16and
  • 41:18especially in the first three
  • 41:19years. And the idea is
  • 41:20that,
  • 41:22that support,
  • 41:24is will allow you to
  • 41:26reach those goals for the
  • 41:27first, three years
  • 41:28of your,
  • 41:31your time,
  • 41:32as starting your lab. So
  • 41:34that's a significant,
  • 41:35initial,
  • 41:38component of departmental,
  • 41:40support.
  • 41:42Certainly during COVID, the university
  • 41:43and the school of medicine
  • 41:44offered,
  • 41:46faculty support specifically to junior
  • 41:48faculty,
  • 41:49to
  • 41:51deal with the challenges that
  • 41:53arose, during
  • 41:54during the pandemic,
  • 41:56and there's kind of a,
  • 41:57there's also other,
  • 41:59for example, programs for supporting
  • 42:01a postdoc that are internal
  • 42:04Yale supported programs that, multiple
  • 42:06members of the department have
  • 42:08have used.
  • 42:12Let's see.
  • 42:16There is a question about,
  • 42:18I'm gonna paraphrase,
  • 42:21you know, research program
  • 42:23that
  • 42:25has implications in human health
  • 42:26and disease but is not
  • 42:28directly related to pathogenesis.
  • 42:32I think I would I
  • 42:33mean, without knowing the specifics,
  • 42:34I would still encourage,
  • 42:36encourage applications
  • 42:38there.
  • 42:39The department is focused on
  • 42:40microbial pathogenesis, and that's, I
  • 42:42think, an area that we
  • 42:43provide key expertise,
  • 42:45that interfaces with many other
  • 42:47areas of the university.
  • 42:49So, again, our focus is
  • 42:51on is on microbial pathogenesis,
  • 42:53but also we're open minded
  • 42:55in terms of of,
  • 42:57individual
  • 42:58applications.
  • 43:02There should be a bug,
  • 43:03though.
  • 43:05Yes.
  • 43:09No bug. Probably no no
  • 43:11go.
  • 43:12Yeah.
  • 43:16Here's a question about the
  • 43:18cover letter. You know, would
  • 43:19it be helpful to
  • 43:21highlight
  • 43:23examples of mentorship or service
  • 43:25in the in the cover
  • 43:26letter or what should be
  • 43:27in the cover letter?
  • 43:29Everyone here is members of
  • 43:30the search committee. What do
  • 43:32you look at in the
  • 43:32cover letter?
  • 43:34Any comments there?
  • 43:38I typically don't read cover
  • 43:39letters, so I
  • 43:46just being honest.
  • 43:50Yeah. I think the most
  • 43:50important component of your application
  • 43:52is your is your description
  • 43:53of your future research plans.
  • 43:55I think We're really yeah.
  • 43:57We're really looking for
  • 43:59your vision of what your
  • 44:00lab would look like, and
  • 44:02I think that shines through
  • 44:03a lot more in the
  • 44:04in that component of the
  • 44:05application than in a cover
  • 44:07letter.
  • 44:09Yeah.
  • 44:10Yeah. I think writing a
  • 44:11clear and concise,
  • 44:13research statement that kind
  • 44:15of lays out
  • 44:18what you've done
  • 44:19and where you wanna go
  • 44:20in the future and how
  • 44:22that interfaces
  • 44:24with the department.
  • 44:26That's really in the first
  • 44:28pass of applications,
  • 44:31kind of what
  • 44:32I think most of the
  • 44:33reviewers look at. It's kind
  • 44:34of like, what's this person
  • 44:35done? What do they want
  • 44:37to do? And how does
  • 44:38that fit into our mission?
  • 44:40And
  • 44:44I I would add that
  • 44:45when we get to the
  • 44:46interview stage, there will be
  • 44:48you know, that's also an
  • 44:49opportunity to learn more about
  • 44:50your,
  • 44:52perspective on mentorship and and
  • 44:54experience, and that will include,
  • 44:57meetings with trainees in the
  • 44:58department.
  • 44:59And we do,
  • 45:01ask for their feedback too,
  • 45:04once we get to that
  • 45:05stage.
  • 45:08Okay.
  • 45:13There is a question
  • 45:17about,
  • 45:18you know,
  • 45:20whether
  • 45:21it's possible as a new
  • 45:23faculty member to attract graduate
  • 45:25students
  • 45:26or postdocs?
  • 45:31Graduate students love new labs
  • 45:34to the point where I
  • 45:35I often have to mentor
  • 45:36new faculty that you don't
  • 45:38need to take every graduate
  • 45:39student that shows an interest
  • 45:40in your lab and accept
  • 45:41them into your lab. Take
  • 45:42the ones that best fit
  • 45:44your culture
  • 45:45and best,
  • 45:46you know,
  • 45:49show an interest in what
  • 45:50you're doing,
  • 45:51because
  • 45:53they will come
  • 45:55to you, and they like
  • 45:57new PIs. They like PIs
  • 45:58who are still working in
  • 45:59the lab.
  • 46:01And and,
  • 46:03I think some of the
  • 46:04biggest challenges for new PIs
  • 46:06here
  • 46:07are they
  • 46:09were desperate to have graduate
  • 46:10students. They've taken three or
  • 46:11four graduate students in the
  • 46:13the the first two years,
  • 46:14and now they're having problems
  • 46:15with them
  • 46:16because they didn't really select,
  • 46:20appropriately.
  • 46:22Getting them is not a
  • 46:23problem. Yeah.
  • 46:26Yeah. I think that's right.
  • 46:27Yeah. We just our a
  • 46:28brand new lab just started
  • 46:29in our department, and she
  • 46:30already has two graduate students
  • 46:32that joined the first year.
  • 46:33And I I had two
  • 46:34join my my first year
  • 46:36as well.
  • 46:37So they they come they
  • 46:38often come in pairs. It's
  • 46:40yeah. It's not a problem.
  • 46:42We have a question about,
  • 46:44joint appointments.
  • 46:46And is this possible
  • 46:48after establishing an independent lab?
  • 46:53Craig, maybe since you have
  • 46:54a secondary appointment, do you
  • 46:56wanna talk a little bit
  • 46:57about about that?
  • 46:59Sure. I mean, you know,
  • 47:01when I got here,
  • 47:03you know, we were actually
  • 47:04so so I was one
  • 47:05of the founding members of
  • 47:06this department, and and we
  • 47:08originally started as three people.
  • 47:10And we were really run
  • 47:12out of cell biology.
  • 47:13So this department was kinda
  • 47:15formed,
  • 47:16with the understanding that we
  • 47:18need to
  • 47:19develop a better understanding between
  • 47:21how
  • 47:22microbes
  • 47:23interact with the host and
  • 47:24and manipulate the cell biology
  • 47:26of the host. And cell
  • 47:27biology was really big on
  • 47:28bringing
  • 47:29bugs here because there were
  • 47:30no bug people.
  • 47:33And we didn't need any
  • 47:35sort of joint appointments to
  • 47:36get cell biology students or
  • 47:38or to interact with the
  • 47:40cell biologists, and I never
  • 47:41asked for
  • 47:43a joint appointment because administratively,
  • 47:46you know, what what was
  • 47:48the reason behind it? I
  • 47:49think you only want to
  • 47:50have a joint appointment.
  • 47:52Or maybe sometimes you don't
  • 47:53even want to have a
  • 47:54joint appointment, but you're asked
  • 47:56to be a joint appointee
  • 47:58because
  • 47:59you do will contribute
  • 48:03towards the mission of that
  • 48:04department in
  • 48:06in in other ways. So
  • 48:08for instance, I'm a joint
  • 48:09appointee in immunobiology,
  • 48:11which means
  • 48:12I teach, you know, the
  • 48:14immunobiology
  • 48:14course. I
  • 48:16participate in a lot of
  • 48:17the the
  • 48:19the the faculty activities within
  • 48:20that
  • 48:21department. But I was a
  • 48:22member of the immunobiology
  • 48:24graduate program for ten years
  • 48:25before they,
  • 48:27you know, offered me a
  • 48:28joint appointment, and I never,
  • 48:30you know, requested one because
  • 48:32why do you wanna look
  • 48:33for more work than you
  • 48:34already have?
  • 48:36So so,
  • 48:38you know, because of the
  • 48:39umbrella program, because of the,
  • 48:41you know, the lack of
  • 48:43scientifically
  • 48:44departmental lines are very meaningless
  • 48:46here,
  • 48:48there's not a lot of
  • 48:49reasons to have a joint
  • 48:50appointment unless,
  • 48:52you're in a clinical department
  • 48:55and you want access to
  • 48:57graduate students because here at
  • 48:59Yale,
  • 49:00clinical faculty can't train graduate
  • 49:03students. They don't have access
  • 49:04to the the the PhD
  • 49:06programs,
  • 49:08unless they get a joint
  • 49:09appointment with a basic science
  • 49:11department.
  • 49:12But the job we're talking
  • 49:13about, you get a basic
  • 49:15science
  • 49:15appointment. So you're a member
  • 49:17of the Graduate School of
  • 49:18Arts and Sciences,
  • 49:20and you are you're qualified
  • 49:21to to
  • 49:23mentor PhD students.
  • 49:25So there there there's very
  • 49:26few reasons why you would
  • 49:27want to have a joint
  • 49:28appointment. If you wanted one,
  • 49:30you know, it's certainly something
  • 49:31that can always be discussed
  • 49:32and always be
  • 49:34negotiated.
  • 49:36But just to have a
  • 49:36title by your name,
  • 49:39you know, there's really no
  • 49:40need for it.
  • 49:43Great. The okay. We're gonna
  • 49:45shift gears a bit. We
  • 49:46got a question. What's it
  • 49:47like raising kids around Yale?
  • 49:49What do you typically do
  • 49:50with them on the weekend?
  • 49:53Well, we have a beach,
  • 49:55lots of beaches,
  • 49:56lots of zoos,
  • 49:58lots of museums right here
  • 50:00in new in New Haven.
  • 50:01When my kids were little,
  • 50:02the Peabody Museum was a
  • 50:04favorite spot. They knew every
  • 50:06single
  • 50:07diorama,
  • 50:08all the rocks, all of
  • 50:09the dinosaurs.
  • 50:12You know, there's music everywhere
  • 50:14here, theater.
  • 50:16You know,
  • 50:18I have to say
  • 50:19having had multiple opportunities to
  • 50:22go to other institutions,
  • 50:25one thing that's always kept
  • 50:26me here at Yale
  • 50:28other than just the remarkable
  • 50:30colleagues, which is first and
  • 50:31foremost,
  • 50:32is just the ease of
  • 50:33living here, raising a family,
  • 50:36and the the the low
  • 50:38stress
  • 50:39involved in all of that.
  • 50:41You know, Hesper and Yachi
  • 50:43have
  • 50:44little kids and a little
  • 50:45older kids, so maybe they
  • 50:46can comment on
  • 50:48how how how that transition
  • 50:49has gone for them since
  • 50:51they've
  • 50:51they've arrived.
  • 50:54Yeah. I if you know,
  • 50:55I'm not from Connecticut.
  • 50:57And if you told me,
  • 50:58like, ten years ago that
  • 50:59I would be living in
  • 51:00Connecticut, I would have probably
  • 51:01laughed in your face, but
  • 51:02I actually love living here.
  • 51:04And I love specifically living
  • 51:05in New Haven. I live
  • 51:07right by the undergraduate campus.
  • 51:09So I actually bike my
  • 51:10kid around everywhere. And I
  • 51:12bike him to school and
  • 51:13then I bike to work,
  • 51:14and, it's just very easy
  • 51:16to live here in a
  • 51:17way that in other,
  • 51:19places, you know, with universities
  • 51:21that are like, you know,
  • 51:22it's not as easy.
  • 51:23So, you know, I take
  • 51:24my yeah. Like I like
  • 51:26Craig said, I take I
  • 51:26actually live right next to
  • 51:27the Peabody, so we go
  • 51:28there a lot.
  • 51:30We, you know, we go
  • 51:32we have we are members
  • 51:33of a pool, so we
  • 51:34go to the pool a
  • 51:35lot. We go to the
  • 51:36beach. We go you know,
  • 51:37there's just so many cool
  • 51:38things to do with kids.
  • 51:40You go we we take
  • 51:41him into New York City.
  • 51:43You know, he likes going
  • 51:44on train rides, things of
  • 51:45that. And it it's just
  • 51:46it's very easy, to live
  • 51:48here. And and if you
  • 51:49have kids, you know, all
  • 51:50of us, I think, in
  • 51:50the department have kids. Like,
  • 51:51we can all talk about
  • 51:53schools
  • 51:54and all the you know,
  • 51:55where to live and all
  • 51:56of these things.
  • 51:57But, you know, I'm I'm
  • 51:58very happy here, and, it's,
  • 52:00yeah.
  • 52:01Now I think I will
  • 52:02continue to talk about five
  • 52:03hours about this. Basically,
  • 52:05at your your start of
  • 52:06your career, you're starting as
  • 52:07assistant professor. You have a
  • 52:08family to raise. This is
  • 52:10really the best place because
  • 52:11life is really easy. We
  • 52:13we get the the the
  • 52:14the price you spend in
  • 52:15those big cities. I got
  • 52:16a huge house. It's even
  • 52:17the lawn is too big
  • 52:18to mount. It's just it's
  • 52:19just wonderful living here. There
  • 52:21are many different activities. You
  • 52:22can you can see, you
  • 52:23know, near New Haven. Also,
  • 52:25we go to New York
  • 52:26a lot. We're very close
  • 52:27to the beach. We're in
  • 52:28the northeast.
  • 52:29I would like to add
  • 52:30on to this location thing
  • 52:32is that because we're in
  • 52:33New Haven, our living expenses
  • 52:35way lower, not only to
  • 52:36sustain a family. I take
  • 52:38my whole lab to Boston,
  • 52:39to New York, to Philadelphia,
  • 52:40and NIH at least twice
  • 52:42a year. My whole lab,
  • 52:43I just put them in
  • 52:44an Airbnb that I can
  • 52:45let them talk to these
  • 52:46collaborators,
  • 52:47like, participate in NIH meetings
  • 52:49that they have actually affordable
  • 52:50living. I also have affordable
  • 52:52living. So doing science and
  • 52:53and enjoy life is actually
  • 52:55pretty good here. It's quite
  • 52:57unique.
  • 52:58Yeah. And I would add
  • 52:59too. One thing I've really
  • 53:00liked about,
  • 53:02living here is just how
  • 53:03many different options there are.
  • 53:04So even just among this
  • 53:06panel, I think each of
  • 53:07us lives in different areas,
  • 53:11in the New Haven area.
  • 53:13So there's some faculty who,
  • 53:15like Hesper said, live right
  • 53:16downtown,
  • 53:17like to work,
  • 53:19walk to restaurants, everything like
  • 53:21that.
  • 53:22And I live about twenty
  • 53:24minutes outside of New Haven
  • 53:26in a smaller town,
  • 53:28near the beach and love
  • 53:30that. There's other other faculty
  • 53:32who live a bit to
  • 53:33the north, you know, where
  • 53:34there's more, like, forests and
  • 53:36hiking trails and things like
  • 53:37that. So, really, you have
  • 53:39your choice in terms of,
  • 53:42like, what kind of living
  • 53:44environment you you want,
  • 53:47when you when you're here
  • 53:49in in New Haven.
  • 53:52There's a bunch of questions
  • 53:54about,
  • 53:55preprints and bioRxiv.
  • 53:58Maybe to summarize them,
  • 54:01I think they in general
  • 54:03are asking,
  • 54:04you know, whether preprints can
  • 54:05be included in an application,
  • 54:08and how they,
  • 54:10relate to peer reviewed publications.
  • 54:14Anybody wanna take that one?
  • 54:18I mean, I would highly
  • 54:19encourage it. I think preprints,
  • 54:21I I are great. I
  • 54:23mean, at least, you know,
  • 54:24that's my view, and,
  • 54:26and I certainly would encourage
  • 54:27it as part of an
  • 54:28application. I think it really
  • 54:29shows that you have a
  • 54:30finished product,
  • 54:32that has, hopefully been submitted
  • 54:34to a journal,
  • 54:35and I think it gives
  • 54:36a lot of value to
  • 54:37an application.
  • 54:39You know, I will say
  • 54:39that,
  • 54:41you know, when I
  • 54:43came here, when I got
  • 54:44this job, I actually didn't
  • 54:45have
  • 54:45my postdoc paper completely published
  • 54:48yet. And one of the
  • 54:49things that really attracted me
  • 54:51to this department was that
  • 54:52they were reliant on their
  • 54:54own estimation
  • 54:55of my work and not
  • 54:56the estimation of a journal
  • 54:58editor.
  • 54:59And that really,
  • 55:00you know, was a huge
  • 55:02positive in my,
  • 55:04in my book. I think,
  • 55:05you know,
  • 55:06my colleagues want,
  • 55:08you know, accepting and and
  • 55:09understanding how that my work
  • 55:11was exciting,
  • 55:13you know, to them was
  • 55:13was, yeah, just really valuable
  • 55:15and really showed that they
  • 55:17have their own minds,
  • 55:19and are, using them. So
  • 55:25Right.
  • 55:26Well said, Hesper.
  • 55:29Yes.
  • 55:33Okay.
  • 55:34Well, we're kind of coming
  • 55:36to the end. I I
  • 55:38know that I haven't
  • 55:40covered everything. Oh, maybe I'll
  • 55:42grab one more question here
  • 55:44about,
  • 55:45the tenure
  • 55:46process and tenure timelines.
  • 55:50And, you know, briefly, maybe
  • 55:52I'll start and you guys
  • 55:53can chime in.
  • 55:55The appointment again is at
  • 55:56the assistant professor level.
  • 55:59There is,
  • 56:00an initial review at the
  • 56:02three year point,
  • 56:04and then a second review,
  • 56:06which is typically,
  • 56:09approximately
  • 56:11three years after that,
  • 56:13for the promotion to associate
  • 56:15professor on term. So that
  • 56:16is
  • 56:17not a tenure,
  • 56:19promotion, but it's a promotion
  • 56:20to associate professor. The tenure
  • 56:22promotion follows,
  • 56:24next, to the level of
  • 56:26associate professor with tenure,
  • 56:29and and then the professor
  • 56:30appointment is is after that.
  • 56:32So typically,
  • 56:34the maximum
  • 56:35combined amount of time for
  • 56:37the assistant and associate
  • 56:39on term
  • 56:40length is ten years.
  • 56:43Although again, there can be
  • 56:44lots of individual circumstances there.
  • 56:47I think the important thing
  • 56:48to say is you're not
  • 56:49on your own in navigating
  • 56:50the tenure process. It's something
  • 56:52that I talk with junior
  • 56:53faculty about,
  • 56:54quite a bit
  • 56:56along the way as well
  • 56:57as their mentoring
  • 56:58committee.
  • 57:00And,
  • 57:02yeah, the goal is to
  • 57:03provide that guidance and experience
  • 57:05so that it's something that
  • 57:07is consistent with your overall
  • 57:09goals as a scientist.
  • 57:10It is not, something that,
  • 57:14we kind of work on
  • 57:15separately from
  • 57:16generally
  • 57:17having a successful and exciting
  • 57:19research program.
  • 57:22Other comments about the tenure
  • 57:24process?
  • 57:26When when I
  • 57:28was considering coming here, having
  • 57:30been at another institution for
  • 57:31two years,
  • 57:33the comment I received at
  • 57:34my other institution was, why
  • 57:35would you wanna go to
  • 57:36Yale? You're you're gonna get
  • 57:37tenure here in three years.
  • 57:40You know, you may not
  • 57:40even get tenure there.
  • 57:42And my response to that
  • 57:44was always, well, if I
  • 57:45can't get tenure, I have
  • 57:47bigger problems
  • 57:48because my career has not
  • 57:50gone as I envisioned it.
  • 57:51So you know? And I
  • 57:53think that holds true here.
  • 57:56We we strive
  • 57:59to select people that we're
  • 58:00confident will get tenure because
  • 58:02they're great scientists. They have
  • 58:04a great vision for their
  • 58:05future,
  • 58:06and and we wanna do
  • 58:07everything we can to help
  • 58:09them,
  • 58:10you know, fulfill that vision.
  • 58:12And tenure is gonna happen
  • 58:14as a consequence. It's it's
  • 58:15not something you're you're
  • 58:17you should really worry about.
  • 58:18And,
  • 58:20you know, some people argue
  • 58:21that our clock is too
  • 58:22long.
  • 58:24You know, it can be
  • 58:24as short as you want.
  • 58:27Right?
  • 58:28But it also gives you
  • 58:30the
  • 58:31the
  • 58:32margin
  • 58:33to really develop new projects
  • 58:35and to do science that
  • 58:37you really want to do
  • 58:39and fulfill your vision
  • 58:41rather than be rushed into
  • 58:42getting, you know,
  • 58:44x number of papers in
  • 58:46five and a half to
  • 58:46six years
  • 58:48because that's what you need
  • 58:49to meet the the the
  • 58:51requirements for university
  • 58:53x's tenure decision. Right? We
  • 58:55we really want you to
  • 58:56develop
  • 58:57as an independent science,
  • 58:59fulfill your scientific vision,
  • 59:01and
  • 59:03a consequence of that will
  • 59:04be you get tenure. No
  • 59:05big deal.
  • 59:08Great.
  • 59:10There's one maybe this will
  • 59:11be the last question I
  • 59:12cover here,
  • 59:14about
  • 59:14support,
  • 59:16for partners,
  • 59:17getting a job, in the
  • 59:18New Haven area if you
  • 59:20apply.
  • 59:21That is something,
  • 59:23what I think you'll see
  • 59:25when,
  • 59:26like, for example, at the
  • 59:27interview stage is that we
  • 59:29we actually don't ask,
  • 59:31about,
  • 59:32you know, partners at that
  • 59:34point because
  • 59:35the the recruitment is really
  • 59:37focused on you as a
  • 59:38scientist, and that's not a
  • 59:40factor that,
  • 59:41we use to,
  • 59:44you know,
  • 59:46prioritize certain people over others.
  • 59:48That said, after the offer
  • 59:50is made, I do jump
  • 59:51in with both feet in
  • 59:52finding
  • 59:53opportunities for partners, and that's
  • 59:55involved,
  • 59:56both working across the university,
  • 59:59not just the school of
  • 60:00medicine, but also other,
  • 01:00:02the undergraduate campus all across
  • 01:00:04the university,
  • 01:00:05working with local biotech, for
  • 01:00:07example,
  • 01:00:09to find opportunities
  • 01:00:11for, partners. So,
  • 01:00:13it is again, it is
  • 01:00:14not a it's not a,
  • 01:00:16you know, something that will
  • 01:00:17penalize your application if your
  • 01:00:20partner has specific job requirements.
  • 01:00:22We will only,
  • 01:00:25start working on that after
  • 01:00:26we,
  • 01:00:27extend an offer, But then
  • 01:00:29once we get to that
  • 01:00:30point, it is something we,
  • 01:00:31work work hard on.
  • 01:00:34So with that, we've hit
  • 01:00:35one o'clock. Thank you all
  • 01:00:37for the really good questions,
  • 01:00:39and,
  • 01:00:41I hope that this was
  • 01:00:43was helpful.
  • 01:00:44Thank you to the panelists,
  • 01:00:45for your really good answers,
  • 01:00:48and again, if there are
  • 01:00:49questions that that I didn't
  • 01:00:51get to or misinterpreted,
  • 01:00:53just email me. I'm happy
  • 01:00:55to,
  • 01:00:56follow-up
  • 01:00:57more.
  • 01:00:59Again, I strongly encourage you
  • 01:01:00to apply and look forward
  • 01:01:01to seeing all your applications,
  • 01:01:05fairly soon.
  • 01:01:06Okay. Bye, everyone. Take care.