Voluntary faculty are typically clinicians or others who are employed outside of the School but make significant contributions to department programs at the medical center or at affiliate institutions.
Voluntary rank detailsMelissa Perkal, MD
Associate Clinical ProfessorAbout
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Titles
Associate Clinical Professor of Surgery (General, Trauma & Surgical Critical Care)
Director of Surgical Preceptor Program
Biography
Associate Professor of Surgery (Trauma); Assistant Chief of Surgery, VA Connecticut Healthcare System; Director, Surgical Intensive Care Unit, VA Connecticut Healthcare System
Dr. Perkal has certifications from the American Board of Surgery in General Surgery and in Surgical Critical Care.
Dr. Perkal earned her undergraduate degree from Yale University and her medical degree from George Washington University School of Medicine. She completed her residency training in general surgery from Yale University School of Medicine and completed her post-doctoral fellowship in Clinical Transplantation at Yale University School of Medicine.
She is currently the Director of the Surgical ICU and Assistant Chief of Surgery at the Connecticut Veterans Administration Hospital, West Haven Campus. She has a long-standing interest in quality improvement in patient care and is now extensively involved in teaching surgical residents about geriatric issues. She is the PI on a Hartford Foundation Grant to improve geriatric teaching in the ICU.
Dr. Perkal’s national service includes being the Chair of the National Surgical Critical Care Board, President of the Yale Surgical Society, and a member of the Steering committee for Oddsdottir Memorial Lectureship. As part of Dr. Perkal’s role as Chair of the Surgical Critical Care Board, she makes numerous visits to ICUs all over the country when their NSQIP numbers fall.
Dr. Perkal is a reviewer for Annals of Long-Term Care, Clinical Geriatrics, and Journal of Clinical Gastroenterology. She has published on topics about clinical transplantation, trauma, glycemic control, central-line infections, and on surgery in the elderly.
Appointments
General Surgery, Trauma & Surgical Critical Care
Associate Clinical ProfessorPrimary
Other Departments & Organizations
- General Surgery, Trauma & Surgical Critical Care
- Palliative and End-of-Life Care Education
- Surgery
- Yale Ventures
Education & Training
- Clinical Fellow
- Yale University School of Medicine, New Haven, CT (1990)
- Resident
- Yale-New Haven Hospital, New Haven, CT (1985)
- MD
- George Washington University (1984)
Research
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Overview
Medical Research Interests
Research at a Glance
Yale Co-Authors
Publications Timeline
Ira Leeds, MD, MBA, FACS, FASCRS
Joseph King Jr, MD, MSCE, FAANS
Vanita Ahuja
Former YSMShilpa Murthy, MD, MPH
Cynthia Brandt, MD, MPH
Alexandria Brackett, MLIS, AHIP, MA
Publications
2026
A Scoping Review of Surgical Care for People Experiencing Homelessness With Cancer
Allen H, Feng W, Falker C, Brackett A, Brandt C, Agbafe V, Allen E, Bagga A, Esdaille J, Reddy V, Mongiu A, Macero N, Pantel H, Perkal M, Murthy S. A Scoping Review of Surgical Care for People Experiencing Homelessness With Cancer. Journal Of Surgical Oncology 2026, 133: 689-697. PMID: 41671112, DOI: 10.1002/jso.70207.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAltmetricConceptsSurgical careScoping ReviewFollow-up careCare coordinationCancer presentationTargeted interventionsSurgical specialistsCareHousing supportCancer surgeryCancer patientsPEHPolicy initiativesTargeted researchCancerSurgical outcomesPeopleInterventionThemesAdvanced stageHomelessnessSpecialistsOutcomesSupport
2024
Evaluating the Safety of Empiric Tamsulosin to Prevent Postoperative Urinary Retention in a Colorectal Surgery Recovery Pathway
Schultz K, Butensky S, Hickey T, Ahuja V, Perkal M, Murthy S, Cavallo J, Leeds I. Evaluating the Safety of Empiric Tamsulosin to Prevent Postoperative Urinary Retention in a Colorectal Surgery Recovery Pathway. Annals Of Surgery Open 2024, 5: e511-e511. PMID: 39711672, PMCID: PMC11661766, DOI: 10.1097/as9.0000000000000511.Peer-Reviewed Original ResearchAltmetricRisk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study
Holleck J, Han L, Skanderson M, Bastian L, Gunderson C, Brandt C, Perkal M, Chang J, Akgün K. Risk of Serious Adverse Gastrointestinal Events with Potassium Binders in Hospitalized Patients: A National Study. Journal Of General Internal Medicine 2024, 40: 518-524. PMID: 39103605, PMCID: PMC11861845, DOI: 10.1007/s11606-024-08979-1.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAdjusted odds ratiosSodium zirconium cyclosilicateU.S. Department of Veterans Affairs healthcare systemDepartment of Veterans Affairs healthcare systemVA Corporate Data WarehouseVeterans Affairs Healthcare SystemCorporate Data WarehousePotassium bindersHospitalized patientsGI eventsHealthcare systemOdds ratioAdverse GI eventsSodium polystyrene sulfonateNational studyPotassium-binding drugsComparative riskAdverse gastrointestinal eventsGI adverse eventsTreatment of hyperkalemiaZirconium cyclosilicateGastrointestinal eventsPatiromerAdverse eventsSurgical Outcomes and Utilization of Laparoscopic Versus Robotic Techniques for Elective Colectomy in Asian American and Native Hawaiian-Pacific Islanders (AAPI) Diagnosed With Colon Cancer
Ahuja V, Murthy S, Leeds I, Paredes L, Su D, Tsutsumi A, Perkal M, King J. Surgical Outcomes and Utilization of Laparoscopic Versus Robotic Techniques for Elective Colectomy in Asian American and Native Hawaiian-Pacific Islanders (AAPI) Diagnosed With Colon Cancer. Journal Of Surgical Research 2024, 302: 40-46. PMID: 39083904, DOI: 10.1016/j.jss.2024.07.007.Peer-Reviewed Original ResearchCitationsConceptsLaparoscopic colectomyRobotic colectomyAAPI patientsColorectal cancerLength of stayClinical outcomesNative Hawaiian Pacific IslanderAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseOperative timeQuality Improvement Program databaseMultivariate logistic regression analysisMean operative timeColorectal cancer resectionOutcomes of LCMinimally invasive approachMultivariate logistic regressionStandard of careLogistic regression analysisElective RCElective LCAnastomotic leakElective colectomySurgical outcomes
2023
Racial disparities in complications following elective colon cancer resection: Impact of laparoscopic versus robotic approaches
Ahuja V, Paredes L, Leeds I, Perkal M, Tsutsumi A, Bhandarkar S, King J. Racial disparities in complications following elective colon cancer resection: Impact of laparoscopic versus robotic approaches. The American Journal Of Surgery 2023, 227: 85-89. PMID: 37806892, PMCID: PMC10842593, DOI: 10.1016/j.amjsurg.2023.09.038.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRC patientsLaparoscopic colectomyElective colon cancer resectionImpact of laparoscopicACS-NSQIP databaseColon cancer resectionMultivariable logistic regressionCancer resectionWhite patientsBlack patientsRobotic colectomyHigher complicationsOperative approachMinority patientsPatientsComplicationsColectomyLogistic regressionRobotic approachRacial disparitiesLaparoscopicCausal pathwaysLower ratesOutcomesMortalityClinical outcomes of elective robotic vs laparoscopic surgery for colon cancer utilizing a large national database
Ahuja V, Paredes L, Leeds I, Perkal M, King J. Clinical outcomes of elective robotic vs laparoscopic surgery for colon cancer utilizing a large national database. Surgical Endoscopy 2023, 37: 7199-7205. PMID: 37365394, DOI: 10.1007/s00464-023-10215-6.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAnastomotic leak rateBody mass indexLarge national databaseOverall complicationsAnastomotic leakOperative timeInvasive colectomyColon cancerElective colon cancer resectionHigher Body Mass IndexNational databaseOperating roomPost-operative lengthColon cancer resectionLonger operative timeRange of surgeryNon-Hispanic whitesCancer resectionACS-NSQIPLaparoscopic colectomyClinical outcomesMass indexLaparoscopic counterpartLaparoscopic surgeryPatient outcomes
2017
Ten-year Experience with Percutaneous Cholecystostomy for Acute Cholecystitis in Men
Grisotti G, King J, Bhattacharya B, Schlessel R, Gunabushanam G, Perkal M. Ten-year Experience with Percutaneous Cholecystostomy for Acute Cholecystitis in Men. American Journal Of Interventional Radiology 2017, 1: 6. DOI: 10.25259/ajir-7-2017.Peer-Reviewed Original ResearchAltmetricConceptsIntensive care unitPercutaneous cholecystostomyAcute cholecystitisSurgical cholecystectomyTotal bilirubinSingle-institution retrospective analysisMultivariate logistic regressionHigh early mortalityTen-year experienceLong-term survivalBiliary decompressionRespiratory failureMedian survivalPatient characteristicsDefinitive treatmentMale patientsCare unitBiliary diseaseEarly mortalityMean agePatient populationPrimary diagnosisTreatment outcomesRetrospective analysisOutcome measures
2011
Palliative Care and Decision Making at the End of Life
Perkal M. Palliative Care and Decision Making at the End of Life. 2011, 197-209. DOI: 10.1007/978-1-4419-6999-6_16.ChaptersCitationsConceptsModerate left-sided pleural effusionLeft-sided pleural effusionLower quadrant painLeft lower lobeBenefits of surgerySurrogate decision makersEarly satietyQuadrant painBowel movementsEnd of lifeMild shortnessAbdominal girthPleural effusionSurgery clinicLower lobePalliative careUmbilical herniaComputerized tomographyMild increasePainAtelectasisHerniaSurgeryEffusionLiposarcoma
1993
Percutaneous endoscopic gastrostomy for gastric decompression in metastatic gynecologic malignancies.
Marks W, Perkal M, Schwartz P. Percutaneous endoscopic gastrostomy for gastric decompression in metastatic gynecologic malignancies. Journal Of The American College Of Surgeons 1993, 177: 573-6. PMID: 8266267.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPercutaneous endoscopic gastrostomyEndoscopic gastrostomyGynecologic malignanciesMetastatic gynecologic malignanciesGastric decompressionGastrointestinal obstructionTube placementNasogastric intubationPatientsGastrostomyIntubationMalignancyDecompressionCarcinomatosisTechnical reasonsObstruction
1992
Severe gingival overgrowth associated with cyclosporine and verapamil therapy
Perkal M, Gulino D, Delfini R, Siegel N, Gaudio K, Marks W, Lorber M. Severe gingival overgrowth associated with cyclosporine and verapamil therapy. Clinical Transplantation 1992, 6: 399-402. DOI: 10.1111/j.1399-0012.1992.tb01118.x.Peer-Reviewed Original ResearchConceptsGingival hyperplasiaAntihypertensive therapyTransplant recipientsOperative interventionSide effects of cyclosporineCadaveric renal transplant recipientsCsA dose reductionRenal transplant recipientsRecommended therapeutic strategiesOrgan transplant recipientsExcellent early resultsRoot planingGingival overgrowthGingival diseaseVerapamil therapyDose reductionRenal transplantationApproximately 1 yearTherapeutic strategiesHyperplasiaTherapyPatientsGingivectomyVerapamilCyclosporine
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