Participate in Research
Yale Child Study Center (YCSC) research teams collaborate to investigate the causes, consequences, and prevention of developmental and behavioral health needs in children, adolescents, and their families. YCSC is actively growing in many areas from basic research in the genetic and neurobiological basis of childhood psychiatric disorders to training clinicians around the world in evidence-based mental health service delivery.
Keep reading for a list of the ongoing research efforts at the Yale Child Study Center to find out how you can participate.
ADHD
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Complex Neurodevelopmental Conditions | We are currently recruiting children for a study on repetitive behavior. This study will help us better understand the causes and developmental course of repetitive behavior in children, especially repetitive motor movements involving the fingers, hands, head, or body. We are recruiting children 4 years of age and younger with repetitive behavior, either typically developing, or with autism or other neurodevelopmental conditions such as ADHD. Participation will include a visit to the lab with your child, including a comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples to learn more about genetic factors involved in repetitive behavior. All study visits will occur at the SANA Program at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please fill out our inquiry form or give us a call at (203) 764-5933. | 4 years and younger | comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples | - | Chawarska Lab | call (203) 764-5933 |
Anxiety
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Development of a Scale to Assess Suicide Thoughts and Behaviors among Preteens | Our study is creating a new survey to understand thoughts of self-harm in young children. Your insights will help shape how we address this growing concern. It’s important to note, your child does not need to experience thoughts of self-harm to participate. | 9 to 12 years | Two appointments, approximately 30 minutes each, where both parent and child complete questionnaires. | a total of $100 in gift cards ($50 per visit) | Anxiety and Mood Disorders Program | anxiety.csc@yale.edu or 203-737-4644
|
Parent-Based Treatment for Adolescent Anxiety
| This study aims to test the efficacy of a parent-only treatment for anxiety disorders in teens, SPACE (Supportive Parenting for Anxious Childhood Emotions), by comparing it to another parent-based approach, Parent Education and Support (PES). Teens 14-17 years old with anxiety disorders and their parents may be eligible to participate. Parents and teens complete three assessments involving diagnostic interviews and/or questionnaires. Parents only are randomly assigned to receive 12 weeks of either SPACE or PES. | 14 to 17 | Teens and parents complete questionnaires and diagnostic interviews. Parents only attend 12 weeks of therapy for their teen's anxiety. | Up to $100 | Anxiety and Mood Disorders Program | anxiety.csc@yale.edu
203-737-4644
|
Autism
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
SPARK at Yale | SPARK is a growing community of individuals, families, and researchers on a mission to speed up the understanding of autism. Our aims are to: Collect DNA from saliva samples and information through surveys from 50,000 people with autism and both of their parents and share that data with researchers. Make breakthroughs that were never before possible and return our findings to you. SPARK is sponsored by the Simons Foundation Autism Research Initiative (SFARI) and Yale is one of more than 30 participating hospitals and clinics across the country. Why join SPARK? Find possible genetic causes of autism in your own family and power future autism research for years to come. Join other autism research studies and get updates on the latest autism research. Connect with a community of 1400 SPARK participants in our region! | All ages | saliva collection and questionnaires | up to $50 Amazon gift card | SPARKforAutism.org/Yale | call (203) 785-7539
sparkforautism@yale.edu |
Infant Emotional Development Study | We are currently recruiting infants for a study on emotional development in early childhood. This study will help us develop better methods for early diagnosis and intervention for behavioral and emotional challenges. We are recruiting infants 4 months of age or younger with and without a family history of autism. Participation will include follow-up visits with your infant through 30 months of age. Visits may include assessment of social, adaptive, cognitive, and language development; studies of attention requiring watching videos and listening to sounds; and play-based activities to assess your child’s emotional development. All study visits will occur at our clinic at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please call (203) 764-5933 or email (sanalab@yale.edu). | 4 months or younger | follow-up visits with your infant through 30 months of age; assessment of social, adaptive, cognitive, and language development; watching videos and listening to sounds; play-based activities | - | Chawarska Lab | call (203) 764-5933
sanalab@yale.edu |
Complex Neurodevelopmental Conditions | We are currently recruiting children for a study on repetitive behavior. This study will help us better understand the causes and developmental course of repetitive behavior in children, especially repetitive motor movements involving the fingers, hands, head, or body. We are recruiting children 4 years of age and younger with repetitive behavior, either typically developing, or with autism or other neurodevelopmental conditions such as ADHD. Participation will include a visit to the lab with your child, including a comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples to learn more about genetic factors involved in repetitive behavior. All study visits will occur at the SANA Program at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please fill out our inquiry form or give us a call at (203) 764-5933. | 4 years and younger | comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples | - | Chawarska Lab | call (203) 764-5933 |
Social attention in autistic and non-autistic children with intellectual disability | This project studies attention to social images in autistic children with intellectual disability (ID) and non-autistic children with ID. We are studying behavior and brain systems to better understand the different ways these children experience the social world. Participation involves one or two visits to our offices where children and families will talk to a clinician, complete questionnaires, and watch videos while their brain waves and movement are recorded. Children will receive a clinical evaluation and report as well as compensation of $120. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 3 to 17 years | questionnaires, EEG, eye-tracking, clinical evaluation | 120 | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Brain Imaging Study of Emotion Regulation in Children | If you have a child who is 5 to 15 years old and has disruptive behaviors or has NO disruptive behaviors (such as anger, irritability, or aggression), they may be eligible to participate in a free and confidential study that examines your child’s social and emotional skills. This research will lead to new ways of understanding how children processes and regulate their emotions. The study will require two visits. At each visit you and your child will complete questionnaires, and your child will participate in an fMRI scan. Functional magnetic resonance imaging (fMRI) is a technique for measuring and mapping brain activity that is noninvasive and safe. You will also receive a free psychoeducational assessment describing your child’s social and emotional development. The study is conducted at the Yale Child Study Center by caring and supportive research staff. | 5 to 15 years | questionnaires and fMRI | up to $100 | Ibrahim Lab | emotion@yale.edu |
Pivotal Response Treatment | PRT is a well-studied and effective behavioral treatment for children with autism spectrum disorder (ASD). PRT treatment sessions take place three times a week at the Yale Child Study Center over 16 weeks, and each visit lasts about 1.5 hours. These sessions are play-based, and the PRT team selects games, crafts, and other activities to match the child’s interests while working on social engagement and communication skills. The study requires a successful fMRI before beginning PRT. Before attempting the scan, a phone screener is required to determine the child’s eligibility and answer any questions parents might have. To learn more about this study, contact Emilio Gray (emilio.gray@yale.edu). | 4 to 9 years | 16 weeks of play-based therapy, fMRI, questionnaires, clinical evaluation
| up to $100 | Ventola Lab | Emilio Gray |
Autism Biomarkers Consortium for Clinical Trials | The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) is a research study to understand how to better measure social skills in school-age autistic children. We are currently recruiting both non-autistic children and children with a diagnosis of autism between the ages of 6 and 11 years old. A diagnostic and cognitive evaluation is provided to all participants at no cost and participants will be compensated up to $300. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 6 to 11 years | questionnaires, EEG, eye-tracking, clinical evaluation | up to $300 | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Stem Cell Study in Autism | You and your child are invited to participate in a study conducted by Flora Vaccarino, M.D. and colleagues at the Yale Child Study Center. The purpose of this study is to identify factors that influence brain cell development and function in individuals with Autism Spectrum Disorders. We are focusing on how young brain cells (known as “neuronal stem cells”) turn into mature cells (such as “neurons and glia”) and how they all function. | 6 years and up | - | up to $150 | Program in Neurodevelopment & Regeneration | flora.vaccarino@yale.edu
livia.tomasini@yale.edu |
Comprehensive Therapy for Irritability and Aggression (CTIA) in Autistic Adolescents | The Sukhodolsky Lab is seeking adolescents ages 12 to 19 who have been diagnosed with autism spectrum disorder (ASD) and have elevated levels of irritability to take part in a free and confidential study. Irritability and/or disruptive behaviors may include anger outbursts, temper tantrums, noncompliance, being easily frustrated, physical behaviors, difficulty following directions, and other similarly challenging behaviors. The purpose of this study is to test a novel psychosocial intervention for irritability and aggression in autism (CTIA) in comparison to a supportive psychotherapy control condition. We want to see if CTIA helps reduce irritability and aggressive behavior in adolescents with ASD. Participation involves completing 15 weeks of therapy, which may be conducted in-person at the Yale Child Study Center in New Haven, CT, or remotely by telehealth. Parents and adolescents also complete questionnaires and interviews about symptoms and behaviors before, during, and after treatment. The study provides a comprehensive assessment of autism, including IQ and adaptive function, and treatment for irritability at no cost to families. Families receive up to $250 for participation. Click here to learn more https://medicine.yale.edu/lab/sukhodolsky/ or contact Sydney Anderson at sydeny.anderson@yale.edu or (203) 737-7662. | 12 to 19 years | 15 weeks of therapy (remote or in person), interviews, questionnaires | up to $250 | Sukhodolsky Lab | call (203) 737-7662
sydney.anderson@yale.edu |
EEG study in Adolescents with Autism | This project studies how teens interact with peers in a computer game and in everyday life. Participation includes one or two visits to our lab where families will talk to a clinician, complete questionnaires, and teens will do computer activities while their brain waves are recorded with an electroencephalogram (EEG). We are currently recruiting teens between 13 and 17 years old. Participants will receive a clinical evaluation, assessment report, and compensation of $70. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 13 to 17 years | questionnaires, EEG, eye-tracking, clinical evaluation
| 70 | McPartland Lab | call 203-737-3439
autism@yale.edu |
Neurodevelopmental Biomarkers of Late Diagnosis in Autism | The Sukhodolsky Lab is seeking volunteers to participate in a research study to help to improve access to autism diagnosis. Autistic people aged 16-39 years are invited to answer questions and complete surveys. These activities can be done out loud, by writing, online or using augmentative/alternative communication. The purpose of the study is to advance the knowledge of the autistic experience. We are aiming to learn about why some people get an autism diagnosis when they are young, and other people get an autism diagnosis when they are teens or adults. Participation involves 1-2 visits, and participants will be compensated up to $225 for participating, and results of study assessments can be shared with participants free of charge. In addition to the 1-2 visits, participants may also be invited to complete optional activities at other visits such as: interviews (up to 1 hour) and brain scans using MRI (up to 2-3 hours). For more information our if you are interested in participating, please contact Ms. Emma Simons at sukhodolsky.lab@yale.edu or 203-737-7664. | 16 to 39 years | 1-2 visits, interviews (up to 1 hour), brain scans using MRI (up to 2-3 hours). | up to $225 | Sukhodolsky Lab | call 203-737-7664
sukhodolsky.lab@yale.edu |
Auditory Study in Autism | This study investigates how the brain processes sounds, and why sometimes the same sounds can feel too loud or too quiet. Participation includes a one-time visit to the lab where brain activity is measured using an electroencephalogram (EEG) in response to various sounds. In addition, participants will talk to a clinician, complete questionnaires, and answer online daily questions at home throughout the following week. We are recruiting adults with and without autism between the ages of 18-40 years old. Participants will be compensated up to $75 for their time. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | questionnaires, EEG, eye-tracking, clinical evaluation, online survey | up to $65 | McPartland Lab | call 203-737-3439
autism@yale.edu |
Transcranial Magnetic Stimulation (TMS) Study | This study will evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS), a type of noninvasive brain stimulation. TMS is a therapy that has been approved for depression and obsessive-compulsive disorder and we are looking to see if it can also help autistic people. This method uses magnetic waves to influence brain activity. Participation includes two visits that involve answering questions and solving puzzles, as well as a recording of brain waves (using EEG) and watching videos on a computer screen. Compensation is $100 per visit. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | clinical assessments, TMS, EEG and eye tracking experiments | $100 per visit | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Transcranial Magnetic Stimulation (TMS) for Depression in Autism | This study will evaluate the effects of Transcranial Magnetic Stimulation (TMS), a type of noninvasive brain stimulation for potentially treating depression in autistic individuals. TMS is a therapy that has been approved for conditions like depression, anxious depression, and obsessive-compulsive disorder. Depression is common in autism so there is a need to better understand why autistic individuals have higher rates of depression than neurotypical individuals. In addition, many autistic individuals with depression may not respond to standard antidepressant medications. In our study, we conduct clinical assessments, then EEG and eye tracking experiments before and after TMS. Study participants will be compensated up to $250. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | clinical assessments, TMS, EEG and eye tracking experiments | up to &250 | McPartland Lab | call 203-737-3439
autism@yale.edu |
The IRIS Study | The IRIS clinical trial is evaluating an oral investigational medication, ML-004, to see if it may help alleviate some of the symptoms that interfere with communication in those with autism spectrum disorder (ASD). Participants may be able to take part in the clinical trial if they are between the ages of 18 and 45 years old, have a diagnosis of autism spectrum disorder (ASD), have a clinical trial/care partner willing to assist during the trial. The clinical trial/care partner is someone who lives with or has frequent contact with the clinical trial participant (parent, spouse, friend, etc.) and is willing and able to provide information about the participant and attend some trial visits. The clinical trial team will discuss additional eligibility criteria with you. | 18 to 45 years | medication, office visits | - | Maplight | marcia.questel@yale.edu or morgan.patterson@yale.edu |
Childhood Disintegrative Disorder
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Yale CDD Study | Does your child have childhood disintegrative disorder (CDD) or autism spectrum disorder (ASD) with a history of normal development followed by a regression (loss of skills) around 3 years of age or later? We invite you to participate in the Yale CDD study. | - | Forms, questionnaires, saliva samples | - | CDD Study | yale.cdd@yale.edu
(203) 868-0653 |
Depression
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Reducing Adolescent Suicide Risk in Treatment-Resistant Depression | Yale is conducting a study to examine the safety, efficacy, response predictors, and post treatment trajectory of adolescents (13–17 years old) with treatment-resistant depression and high suicide risk following a conservative repeat dosing Ketamine infusion paradigm compared to an active control, Midazolam. Those who are randomized to Midazolam and remain ill have the option to cross-over to Ketamine in the open phase. All participants will be followed closely for 4 months post-treatment and treated with standard of care depression treatment (medication management and cognitive behavioral therapy). Brain-based predictors of anti-suicidal responses will be assessed via connectome predictive modeling and examining functional brain circuits via fMRI before and after treatment. Compensation is up to $320. To learn more about this study, contact Brooke Rivera, Clinical Coordinator, Yale Pediatric Depression Lab at (203)785-7880 or email PediDepression@yale.edu. | 13 to 17 years | Ketamine infusion, standard of care depression treatment | up to &320 | Bloch Lab | call 203-785-7880
PediDepression@yale.edu |
Teen Brain Imaging Study | The Cho Lab at Yale is running a research study to examine how the brain supports cognition and motivation in teenagers, ages 13-17 years old. We would like to understand how these brain changes contribute to depression and schizophrenia or psychosis in teenagers. Typically developing teenagers, teenagers who have depression or teenagers who have schizophrenia/psychosis may be eligible to participate. The study is confidential, and teenagers are compensated for their participation. For further details please email ChoLab@yale.edu or call 203-815-9874. | 13 to 17 years | Clinical assessments, MRI, IQ testing | Up to &650 | Cho Lab | call 203-815-9874
ChoLab@yale.edu |
Transcranial Magnetic Stimulation (TMS) for Depression in Autism | This study will evaluate the effects of Transcranial Magnetic Stimulation (TMS), a type of noninvasive brain stimulation for potentially treating depression in autistic individuals. TMS is a therapy that has been approved for conditions like depression, anxious depression, and obsessive-compulsive disorder. Depression is common in autism so there is a need to better understand why autistic individuals have higher rates of depression than neurotypical individuals. In addition, many autistic individuals with depression may not respond to standard antidepressant medications. In our study, we conduct clinical assessments, then EEG and eye tracking experiments before and after TMS. Study participants will be compensated up to $250. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | clinical assessments, TMS, EEG and eye tracking experiments | up to &250 | McPartland Lab | call 203-737-3439
autism@yale.edu |
Functional Neurological Disorder
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
A multi-site feasibility clinical trial of Retraining and Control Therapy (ReACT)
| Yale Child Neurology and Yale Child Study Center are conducting a multi-site research study to examine the effects of two commonly used treatments for improving Functional Neurological Disorder (FND) symptoms, specifically Functional Seizures (FS). | 11 to 18 years | Cognitive Behavioral Therapy (CBT) based treatments are the standard of care for treating pediatric patients with FND symptoms. This study uses two different CBT-based therapies to assess FND treatment outcomes. If you choose, you can undergo the therapy to which you were not randomized to at the end of the study. | up to $250 | FND Study | call 203-479-0316
fndstudy@yale.edu |
Irritability
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Multi-level mechanisms and predictors of chronic irritability | Our research study wants to see how the brain and social and emotional factors help us predict irritability and its changes over two years. | 8 to 13 years | We are looking at irritability and frustration utilizing various procedures, e.g. fMRI (functional Magnetic Resonance Imaging), measuring physiological data (e.g. heart rate), questionnaires, and interviews. | up to $650 | YAY Lab
| call 203-479-0276
affectiveyouth@yale.edu |
Complex Neurodevelopmental Conditions | We are currently recruiting children for a study on repetitive behavior. This study will help us better understand the causes and developmental course of repetitive behavior in children, especially repetitive motor movements involving the fingers, hands, head, or body. We are recruiting children 4 years of age and younger with repetitive behavior, either typically developing, or with autism or other neurodevelopmental conditions such as ADHD. Participation will include a visit to the lab with your child, including a comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples to learn more about genetic factors involved in repetitive behavior. All study visits will occur at the SANA Program at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please fill out our inquiry form or give us a call at (203) 764-5933. | 4 years and younger | comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples | - | Chawarska Lab | call (203) 764-5933 |
Language & Literacy
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Multimodal imaging of language | At the LLAMB Lab, we study explore how young children’s brains process language. Our research uses fMRI and fNIRS, both safe and noninvasive brain imaging techniques, to study brain activity while children watch engaging videos, such as Sesame Street clips. Some children will participate in fMRI, others in fNIRS, and some in both simultaneously.
This study is conducted by researchers at Haskins Laboratories at Yale University, with the goal of better understanding early language development and brain function. | 12 months up to 7 years | demographics surveys, a language questionnaire, neuroimaging such as functional near-infrared spectroscopy (fNIRS) and functional magnetic resonance imaging (fMRI) | $25/hour | LLAMB Lab | lab email: llamblab@haskins.yale.edu; lab manager contact: Virginia Chambers (virginia.chambers@yale.edu) |
Reading Patterns Explored Across Tasks (RePEAT) | The study goal is to identify how children learn language and reading skills both when they are well poised to do so and when they are struggling. We hope to identify the brain mechanisms underlying this learning and isolate what might indicate that a child is especially ready to learn to read. | 7 to 13 years | Behavioral testing, questionaires, MRI scan, fNIRS/EEG | Up to $250 | RePEAT Project Form | 203-785-2381, haskinsreading@yale.edu
|
Misophonia
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Misophonia Genetics Study | The purpose of the Misophonia Genetics Study is to identify the genetic factors that cause misophonia (a condition in which certain sounds trigger an intense emotional or physiological response) using a family-based approach. This will greatly contribute to our understanding of misophonia and may help develop new therapies in the future. This study requires participation from a child and both biological parents. Families will be compensated with a $75 Amazon gift card for the family. | - | saliva collection (child and both parents), questionnaires | $25 Amazon gift card | Misophonia Genetics Study | misophonia@yale.edu |
Online Intervention
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Online Mental Health Intervention for Adolescents on the Waiting List for Mental Health Services | We are currently recruiting adolescents seeking outpatient services at YCSC for a study testing an online mental health intervention conducted while they are on the waiting list. The online mental health intervention is designed to teach coping and emotion regulation skills for adolescents struggling with mental health symptoms. This study will help us better understand how to best implement an online intervention for adolescents on the waiting list. We are recruiting any adolescent aged 13-17 years on the waiting list for services if they are not currently receiving treatment for the same problem elsewhere. Participants must have access to a mobile device. Participation is completely online. Adolescents will answer questions on their mobile phone or tablet and engage with the online intervention for 20-30 minutes. Then, adolescents will participate in either a focus group or individual interview lasting 60-90 minutes to assess their experience with the intervention. Parents will be contacted before adolescent participation for consent and answer any questions they may have. To learn more about our study, please contact accesslab@yale.edu. This study has been approved by the Yale IRB (HIC #2000035977). | 13-17 years | Self-report questionnaires, engaging with an online intervention for mental health, focus groups. | 60 | ACCESS Lab | accesslab@yale.edu |
Parenting
| Study Name | Study Information | Child Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Substance Misuse and Family Violence Treatment for Fathers | We are currently recruiting fathers (of children aged 12 or younger) with a history of substance use and significant conflict with their coparent or significant other for our treatment study. Fathers will be randomly assigned to one of two treatments for substance misuse, Fathers for Change or Individual Drug Counseling. This study will help us learn what programs work best for fathers. Fathers could earn up to $475 for the entire study while receiving weekly individual counseling free of charge. If interested, please contact us at (203) 785-3486 or at fathers4change@yale.edu. | Under 12 years | In the study, fathers would participate in an initial assessment that will take about 3 hours and will be paid $50. Then fathers will be randomly assigned to one of two treatments for substance misuse, Fathers for Change or Individual Drug Counseling, where they will meet once per week for an hour with an assigned counselor for sessions at our clinic and receive $5 per session. Fathers would then attend a post assessment and two follow-up assessments 3 and 6 months later. They will be paid $60, $70, and $75 for attending these assessments. Fathers could earn up to $475 for the entire study. Participation is voluntary and fathers can stop participating at any time | Up to $475 | Fathers for Change | Quyen Do
fathers4change@yale.edu
203-785-7707 |
Comparing a Fatherhood Focused Individual Intervention to Batterer Intervention to Reduce IPV and Child Maltreatment | This study will expand our promising data on Fathers for Change (F4C), a novel intervention for fathers with histories of use of aggression and violence toward their partners and/or children. We will recruit 240 fathers and randomly assign them to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends. We will test whether F4C reduces family violence and improves child symptoms better than BIP. | 3 months to 12 years | Participating fathers will first complete a series of questionnaires and semi -structured interviews with a research assistant. then they will be randomly assigned to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends.` | $50 for initial assessment, $5/wk for 18 weeks of counseling, $60 for post assessment, $70 for 6 and 12 month assessments | Fathers for Change | Keren Lebron Ramos
fathers4change@yale.edu
203-805-8557 |
Parent-Based Treatment for Adolescent Anxiety
| This study aims to test the efficacy of a parent-only treatment for anxiety disorders in teens, SPACE (Supportive Parenting for Anxious Childhood Emotions), by comparing it to another parent-based approach, Parent Education and Support (PES). Teens 14-17 years old with anxiety disorders and their parents may be eligible to participate. Parents and teens complete three assessments involving diagnostic interviews and/or questionnaires. Parents only are randomly assigned to receive 12 weeks of either SPACE or PES. | 14 to 17 | Teens and parents complete questionnaires and diagnostic interviews. Parents only attend 12 weeks of therapy for their teen's anxiety. | Up to $100 | Anxiety and Mood Disorders Program | anxiety.csc@yale.edu
203-737-4644
|
Pregnancy
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
UPWARDS Study | The purpose of the UPWARDS Study is to develop a better approach to identify pregnant individuals who are having difficulty with their emotional wellbeing and may need extra help or support during and after pregnancy. We’d love to have you join and play an important role in our study. | - | passive data collection, questionnaires | up to $190 | UPWARDS Study | Kieran.ODonnell@yale.edu |
Psychological Risk on Mother Infant Study (PROMISE) | Seeking First-Time Expecting Mothers for Research Study with $500 compensation!
We are interested in how the maternal brain changes over pregnancy and postpartum, the role of maternal factors in shaping such changes, and the impact of those changes on parenting and child development.
Click the link if you are interested: https://yalesurvey.ca1.qualtrics.com/.../SV_6FP1gxSi4L0rBeC | 18 to 45 years | EEG, questionnaires, interviews, and caregiving tasks | 500 | BABL Lab | call 203-689-2831
promise@yale.edu |
Schizophrenia/Psychosis
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Teen Brain Imaging Study | The Cho Lab at Yale is running a research study to examine how the brain supports cognition and motivation in teenagers, ages 13-17 years old. We would like to understand how these brain changes contribute to depression and schizophrenia or psychosis in teenagers. Typically developing teenagers, teenagers who have depression or teenagers who have schizophrenia/psychosis may be eligible to participate. The study is confidential, and teenagers are compensated for their participation. For further details please email ChoLab@yale.edu or call 203-815-9874. | 13 to 17 years | Clinical assessments, MRI, IQ testing | Up to &650 | Cho Lab | call 203-815-9874
ChoLab@yale.edu |
Suicide Prevention
| Study Name | Study Information | Child Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Perspectives of Life and Daily Thoughts (Project PLAD)
| The purpose of this study is to examine what perpetuates suicidal thoughts and behaviors (STBs), and identify ways to mitigate it. We aim to achieve this through a longitudinal study assessing future life-oriented (FLO) thinking and clinically-relevant correlates among teens (15-19) and their parents. Participation includes: self-report surveys and observation of parent-child interactions during a zoom research visit, brief micro-surveys via smartphones over 42 days, and stress-hormone collection from nail samples from teens. | 15 to 19 | Procedures include: zoom study visit with individual tasks, observed parent-child interactions and self-report questionnaires, brief micro-surveys through the phone based app Metricwire, and a follow-up zoom session with self-report surveys and observed parent-child interactions. | Up to $300 | Cha Lab | project.plad@yale.edu
203-764-7210
|
Tourette's Disorder
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Neurofeedback from the supplementary motor area for Tourette Syndrome | Does your child have chronic tics or Tourette Syndrome? If your child is 10-16 years old with chronic tics, they may be eligible to receive neurofeedback treatment. We use a form of neurofeedback that involves monitoring brain activity via fMRI. The purpose of this study is to determine if our neurofeedback intervention can reduce tic symptoms and improve our understanding of Tourette Syndrome. Participation can result in compensation up to $880. If you have any further questions or concerns, please contact us at Hampson.lab@yale.edu, or (203)-737-6055. Study Sponsors: National Institute of Mental Health, Department of Human Health Services. HIC#2000033043 | 10 to 16 years | fMRI | up to $880 | Trial Website | call (203)-737-6055
Hampson.lab@yale.edu |
Stem Cell Study in Tourette's Disorder | You and your child are invited to participate in a study conducted by Flora Vaccarino, M.D. and colleagues at the Yale Child Study Center. The purpose of this study is to identify factors that influence brain cell development and function in individuals with Autism Spectrum Disorders and Tourette Syndrome. We are focusing on how young brain cells (known as “neuronal stem cells”) turn into mature cells (such as “neurons and glia”) and how they all function. | 16 years & up | Saliva, blood draw, clinical assessments. | $100 for samples and $100 for clinical assessments | Program in Neurodevelopment & Regeneration | flora.vaccarino@yale.edu
livia.tomasini@yale.edu |
Trauma
| Study Name | Study Information | Child Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Comparing a Fatherhood Focused Individual Intervention to Batterer Intervention to Reduce IPV and Child Maltreatment | This study will expand our promising data on Fathers for Change (F4C), a novel intervention for fathers with histories of use of aggression and violence toward their partners and/or children. We will recruit 240 fathers and randomly assign them to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends. We will test whether F4C reduces family violence and improves child symptoms better than BIP. | 3 months to 12 years | Participating fathers will first complete a series of questionnaires and semi -structured interviews with a research assistant. then they will be randomly assigned to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends.` | $50 for initial assessment, $5/wk for 18 weeks of counseling, $60 for post assessment, $70 for 6 and 12 month assessments | Fathers for Change | Keren Lebron Ramos
fathers4change@yale.edu
203-805-8557 |
Trichotillomania
| Study Name | Study Information | Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
TABS Study | Your family has been invited to be part of a study of families in which an individual has trichotillomania or other body focused repetitive behavior (BFRB). Although it is well known that genetic factors play a role in causing BFRBs, the responsible genes have not yet been discovered. Recent dramatic advances in genetic techniques hold out the promise that we may soon be able to identify such risk-conferring genes. The purpose of this study is to identify the genetic factors that cause trichotillomania and other BFRBs using a family-based approach. This will greatly contribute to our understanding of these conditions and may help develop new therapies in the future. This study requires participation from an individual impacted by trichotillomania or other BFRB and both biological parents. The study can be done in-person or remotely. We are not able to offer you a report of your genetic results because our studies are performed as research. Our research lab does not offer any treatment. | - | Saliva sample (child and both parents), questionnaire | - | TABS Study | tabsstudy@yale.edu |
Valbenazine for the Treatment of Trichotillomania in Adults | If you are an adult with trichotillomania, you may be eligible to participate in an in-person research study run by the Yale School of Medicine. This study will examine the efficacy of Valbenazine for the treatment of trichotillomania. Valbenazine is a dopamine-depleting agent that is currently FDA-approved for tardive dyskinesia and has a relatively safe side-effect profile in initial trials. While enrolled in the trial, you will receive regular psychiatric and medical assessments of symptoms at no cost. Additionally, you will receive a stipend of up to $590 over the course of 26 weeks for your participation. In-person visits occur about every two weeks and are held at 350 George St. New Haven, CT 06511. If you are interested in the trial or wish to learn more, please do not hesitate to contact us by phone at (203)785-7880 or email at blochresearch@yale.edu if you have any questions about the trial. | - | medication, psychiatric and medical assessments | stipend of up to $590 over the course of 26 weeks | Bloch Lab | call (203)785-7880
blochresearch@yale.edu |
Typically Developing Individuals
| Study Name | Study Information | Child Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
Substance Misuse and Family Violence Treatment for Fathers | We are currently recruiting fathers (of children aged 12 or younger) with a history of substance use and significant conflict with their coparent or significant other for our treatment study. Fathers will be randomly assigned to one of two treatments for substance misuse, Fathers for Change or Individual Drug Counseling. This study will help us learn what programs work best for fathers. Fathers could earn up to $475 for the entire study while receiving weekly individual counseling free of charge. If interested, please contact us at (203) 785-3486 or at fathers4change@yale.edu. | Under 12 years | In the study, fathers would participate in an initial assessment that will take about 3 hours and will be paid $50. Then fathers will be randomly assigned to one of two treatments for substance misuse, Fathers for Change or Individual Drug Counseling, where they will meet once per week for an hour with an assigned counselor for sessions at our clinic and receive $5 per session. Fathers would then attend a post assessment and two follow-up assessments 3 and 6 months later. They will be paid $60, $70, and $75 for attending these assessments. Fathers could earn up to $475 for the entire study. Participation is voluntary and fathers can stop participating at any time | Up to $475 | Fathers for Change | Quyen Do
fathers4change@yale.edu
203-785-7707 |
Comparing a Fatherhood Focused Individual Intervention to Batterer Intervention to Reduce IPV and Child Maltreatment | This study will expand our promising data on Fathers for Change (F4C), a novel intervention for fathers with histories of use of aggression and violence toward their partners and/or children. We will recruit 240 fathers and randomly assign them to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends. We will test whether F4C reduces family violence and improves child symptoms better than BIP. | 3 months to 12 years | Participating fathers will first complete a series of questionnaires and semi -structured interviews with a research assistant. then they will be randomly assigned to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends.` | $50 for initial assessment, $5/wk for 18 weeks of counseling, $60 for post assessment, $70 for 6 and 12 month assessments | Fathers for Change | Keren Lebron Ramos
fathers4change@yale.edu
203-805-8557 |
Infant Emotional Development Study | We are currently recruiting infants for a study on emotional development in early childhood. This study will help us develop better methods for early diagnosis and intervention for behavioral and emotional challenges. We are recruiting infants 4 months of age or younger with and without a family history of autism. Participation will include follow-up visits with your infant through 30 months of age. Visits may include assessment of social, adaptive, cognitive, and language development; studies of attention requiring watching videos and listening to sounds; and play-based activities to assess your child’s emotional development. All study visits will occur at our clinic at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please call (203) 764-5933 or email (sanalab@yale.edu). | 4 months or younger | follow-up visits with your infant through 30 months of age; assessment of social, adaptive, cognitive, and language development; watching videos and listening to sounds; play-based activities | - | Chawarska Lab | call (203) 764-5933
sanalab@yale.edu |
Multimodal imaging of language | At the LLAMB Lab, we study explore how young children’s brains process language. Our research uses fMRI and fNIRS, both safe and noninvasive brain imaging techniques, to study brain activity while children watch engaging videos, such as Sesame Street clips. Some children will participate in fMRI, others in fNIRS, and some in both simultaneously.
This study is conducted by researchers at Haskins Laboratories at Yale University, with the goal of better understanding early language development and brain function. | 12 months up to 7 years | demographics surveys, a language questionnaire, neuroimaging such as functional near-infrared spectroscopy (fNIRS) and functional magnetic resonance imaging (fMRI) | $25/hour | LLAMB Lab | lab email: llamblab@haskins.yale.edu; lab manager contact: Virginia Chambers (virginia.chambers@yale.edu) |
Complex Neurodevelopmental Conditions | We are currently recruiting children for a study on repetitive behavior. This study will help us better understand the causes and developmental course of repetitive behavior in children, especially repetitive motor movements involving the fingers, hands, head, or body. We are recruiting children 4 years of age and younger with repetitive behavior, either typically developing, or with autism or other neurodevelopmental conditions such as ADHD. Participation will include a visit to the lab with your child, including a comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples to learn more about genetic factors involved in repetitive behavior. All study visits will occur at the SANA Program at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please fill out our inquiry form or give us a call at (203) 764-5933. | 4 years and younger | comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples | - | Chawarska Lab | call (203) 764-5933 |
Brain Imaging Study of Emotion Regulation in Children | If you have a child who is 5 to 15 years old and has disruptive behaviors or has NO disruptive behaviors (such as anger, irritability, or aggression), they may be eligible to participate in a free and confidential study that examines your child’s social and emotional skills. This research will lead to new ways of understanding how children processes and regulate their emotions. The study will require two visits. At each visit you and your child will complete questionnaires, and your child will participate in an fMRI scan. Functional magnetic resonance imaging (fMRI) is a technique for measuring and mapping brain activity that is noninvasive and safe. You will also receive a free psychoeducational assessment describing your child’s social and emotional development. The study is conducted at the Yale Child Study Center by caring and supportive research staff. | 5 to 15 years | questionnaires and fMRI | up to $100 | Ibrahim Lab | emotion@yale.edu |
Autism Biomarkers Consortium for Clinical Trials | The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) is a research study to understand how to better measure social skills in school-age autistic children. We are currently recruiting both non-autistic children and children with a diagnosis of autism between the ages of 6 and 11 years old. A diagnostic and cognitive evaluation is provided to all participants at no cost and participants will be compensated up to $300. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 6 to 11 years | questionnaires, EEG, eye-tracking, clinical evaluation | up to $300 | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Stem Cell Study in Autism | You and your child are invited to participate in a study conducted by Flora Vaccarino, M.D. and colleagues at the Yale Child Study Center. The purpose of this study is to identify factors that influence brain cell development and function in individuals with Autism Spectrum Disorders. We are focusing on how young brain cells (known as “neuronal stem cells”) turn into mature cells (such as “neurons and glia”) and how they all function. | 6 years and up | - | up to $150 | Program in Neurodevelopment & Regeneration | flora.vaccarino@yale.edu
livia.tomasini@yale.edu |
Reading Patterns Explored Across Tasks (RePEAT) | The study goal is to identify how children learn language and reading skills both when they are well poised to do so and when they are struggling. We hope to identify the brain mechanisms underlying this learning and isolate what might indicate that a child is especially ready to learn to read. | 7 to 13 years | Behavioral testing, questionaires, MRI scan, fNIRS/EEG | Up to $250 | RePEAT Project Form | 203-785-2381, haskinsreading@yale.edu
|
Multi-level mechanisms and predictors of chronic irritability | Our research study wants to see how the brain and social and emotional factors help us predict irritability and its changes over two years. | 8 to 13 years | We are looking at irritability and frustration utilizing various procedures, e.g. fMRI (functional Magnetic Resonance Imaging), measuring physiological data (e.g. heart rate), questionnaires, and interviews. | up to $650 | YAY Lab
| call 203-479-0276
affectiveyouth@yale.edu |
EEG study in Adolescents with Autism | This project studies how teens interact with peers in a computer game and in everyday life. Participation includes one or two visits to our lab where families will talk to a clinician, complete questionnaires, and teens will do computer activities while their brain waves are recorded with an electroencephalogram (EEG). We are currently recruiting teens between 13 and 17 years old. Participants will receive a clinical evaluation, assessment report, and compensation of $70. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 13 to 17 years | questionnaires, EEG, eye-tracking, clinical evaluation
| 70 | McPartland Lab | call 203-737-3439
autism@yale.edu |
Teen Brain Imaging Study | The Cho Lab at Yale is running a research study to examine how the brain supports cognition and motivation in teenagers, ages 13-17 years old. We would like to understand how these brain changes contribute to depression and schizophrenia or psychosis in teenagers. Typically developing teenagers, teenagers who have depression or teenagers who have schizophrenia/psychosis may be eligible to participate. The study is confidential, and teenagers are compensated for their participation. For further details please email ChoLab@yale.edu or call 203-815-9874. | 13 to 17 years | Clinical assessments, MRI, IQ testing | Up to &650 | Cho Lab | call 203-815-9874
ChoLab@yale.edu |
Perspectives of Life and Daily Thoughts (Project PLAD)
| The purpose of this study is to examine what perpetuates suicidal thoughts and behaviors (STBs), and identify ways to mitigate it. We aim to achieve this through a longitudinal study assessing future life-oriented (FLO) thinking and clinically-relevant correlates among teens (15-19) and their parents. Participation includes: self-report surveys and observation of parent-child interactions during a zoom research visit, brief micro-surveys via smartphones over 42 days, and stress-hormone collection from nail samples from teens. | 15 to 19 | Procedures include: zoom study visit with individual tasks, observed parent-child interactions and self-report questionnaires, brief micro-surveys through the phone based app Metricwire, and a follow-up zoom session with self-report surveys and observed parent-child interactions. | Up to $300 | Cha Lab | project.plad@yale.edu
203-764-7210
|
Stem Cell Study in Tourette's Disorder | You and your child are invited to participate in a study conducted by Flora Vaccarino, M.D. and colleagues at the Yale Child Study Center. The purpose of this study is to identify factors that influence brain cell development and function in individuals with Autism Spectrum Disorders and Tourette Syndrome. We are focusing on how young brain cells (known as “neuronal stem cells”) turn into mature cells (such as “neurons and glia”) and how they all function. | 16 years and up | Saliva, blood draw, clinical assessments. | $100 for samples and $100 for clinical assessments | Program in Neurodevelopment & Regeneration | flora.vaccarino@yale.edu
livia.tomasini@yale.edu |
Transcranial Magnetic Stimulation (TMS) Study | This study will evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS), a type of noninvasive brain stimulation. TMS is a therapy that has been approved for depression and obsessive-compulsive disorder and we are looking to see if it can also help autistic people. This method uses magnetic waves to influence brain activity. Participation includes two visits that involve answering questions and solving puzzles, as well as a recording of brain waves (using EEG) and watching videos on a computer screen. Compensation is $100 per visit. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | clinical assessments, TMS, EEG and eye tracking experiments | $100 per visit | McPartland Lab | call (203) 737-3439
autism@yale.edu |
All Studies
| Study Name | Study Information | Child Age | Procedure | Compensation | Website | Contacts |
|---|---|---|---|---|---|---|
SPARK at Yale | SPARK is a growing community of individuals, families, and researchers on a mission to speed up the understanding of autism. Our aims are to: Collect DNA from saliva samples and information through surveys from 50,000 people with autism and both of their parents and share that data with researchers. Make breakthroughs that were never before possible and return our findings to you. SPARK is sponsored by the Simons Foundation Autism Research Initiative (SFARI) and Yale is one of more than 30 participating hospitals and clinics across the country. Why join SPARK? Find possible genetic causes of autism in your own family and power future autism research for years to come. Join other autism research studies and get updates on the latest autism research. Connect with a community of 1400 SPARK participants in our region! | All ages | saliva collection and questionnaires | up to $50 Amazon gift card | SPARKforAutism.org/Yale | call (203) 785-7539
sparkforautism@yale.edu |
Substance Misuse and Family Violence Treatment for Fathers | We are currently recruiting fathers (of children aged 12 or younger) with a history of substance use and significant conflict with their coparent or significant other for our treatment study. Fathers will be randomly assigned to one of two treatments for substance misuse, Fathers for Change or Individual Drug Counseling. This study will help us learn what programs work best for fathers. Fathers could earn up to $475 for the entire study while receiving weekly individual counseling free of charge. If interested, please contact us at (203) 785-3486 or at fathers4change@yale.edu. | Under 12 years | In the study, fathers would participate in an initial assessment that will take about 3 hours and will be paid $50. Then fathers will be randomly assigned to one of two treatments for substance misuse, Fathers for Change or Individual Drug Counseling, where they will meet once per week for an hour with an assigned counselor for sessions at our clinic and receive $5 per session. Fathers would then attend a post assessment and two follow-up assessments 3 and 6 months later. They will be paid $60, $70, and $75 for attending these assessments. Fathers could earn up to $475 for the entire study. Participation is voluntary and fathers can stop participating at any time | Up to $475 | Fathers for Change | Quyen Do
fathers4change@yale.edu
203-785-7707 |
Comparing a Fatherhood Focused Individual Intervention to Batterer Intervention to Reduce IPV and Child Maltreatment | This study will expand our promising data on Fathers for Change (F4C), a novel intervention for fathers with histories of use of aggression and violence toward their partners and/or children. We will recruit 240 fathers and randomly assign them to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends. We will test whether F4C reduces family violence and improves child symptoms better than BIP. | 3 months to 12 years | Participating fathers will first complete a series of questionnaires and semi -structured interviews with a research assistant. then they will be randomly assigned to F4C or a standard Duluth Model program for domestic violence (BIP). Each father will receive 18 weeks of individual counseling with a therapist and participant in 6 and 12 month follow-up assessments after their counseling ends.` | $50 for initial assessment, $5/wk for 18 weeks of counseling, $60 for post assessment, $70 for 6 and 12 month assessments | Fathers for Change | Keren Lebron Ramos
fathers4change@yale.edu
203-805-8557 |
Infant Emotional Development Study | We are currently recruiting infants for a study on emotional development in early childhood. This study will help us develop better methods for early diagnosis and intervention for behavioral and emotional challenges. We are recruiting infants 4 months of age or younger with and without a family history of autism. Participation will include follow-up visits with your infant through 30 months of age. Visits may include assessment of social, adaptive, cognitive, and language development; studies of attention requiring watching videos and listening to sounds; and play-based activities to assess your child’s emotional development. All study visits will occur at our clinic at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please call (203) 764-5933 or email (sanalab@yale.edu). | 4 months or younger | follow-up visits with your infant through 30 months of age; assessment of social, adaptive, cognitive, and language development; watching videos and listening to sounds; play-based activities | - | Chawarska Lab | call (203) 764-5933
sanalab@yale.edu |
Multimodal imaging of language | At the LLAMB Lab, we study explore how young children’s brains process language. Our research uses fMRI and fNIRS, both safe and noninvasive brain imaging techniques, to study brain activity while children watch engaging videos, such as Sesame Street clips. Some children will participate in fMRI, others in fNIRS, and some in both simultaneously.
This study is conducted by researchers at Haskins Laboratories at Yale University, with the goal of better understanding early language development and brain function. | 12 months up to 7 years | demographics surveys, a language questionnaire, neuroimaging such as functional near-infrared spectroscopy (fNIRS) and functional magnetic resonance imaging (fMRI) | $25/hour | LLAMB Lab | lab email: llamblab@haskins.yale.edu; lab manager contact: Virginia Chambers (virginia.chambers@yale.edu) |
Complex Neurodevelopmental Conditions | We are currently recruiting children for a study on repetitive behavior. This study will help us better understand the causes and developmental course of repetitive behavior in children, especially repetitive motor movements involving the fingers, hands, head, or body. We are recruiting children 4 years of age and younger with repetitive behavior, either typically developing, or with autism or other neurodevelopmental conditions such as ADHD. Participation will include a visit to the lab with your child, including a comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples to learn more about genetic factors involved in repetitive behavior. All study visits will occur at the SANA Program at 300 George St., Suite 900, New Haven, CT. We provide free and convenient parking. If you are interested in participating, please fill out our inquiry form or give us a call at (203) 764-5933. | 4 years and younger | comprehensive diagnostic evaluation, assessment of repetitive behavior, studies of attention, and collection of saliva samples | - | Chawarska Lab | call (203) 764-5933 |
Social attention in autistic and non-autistic children with intellectual disability | This project studies attention to social images in autistic children with intellectual disability (ID) and non-autistic children with ID. We are studying behavior and brain systems to better understand the different ways these children experience the social world. Participation involves one or two visits to our offices where children and families will talk to a clinician, complete questionnaires, and watch videos while their brain waves and movement are recorded. Children will receive a clinical evaluation and report as well as compensation of $120. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 3 to 17 years | questionnaires, EEG, eye-tracking, clinical evaluation | 120 | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Pivotal Response Treatment | PRT is a well-studied and effective behavioral treatment for children with autism spectrum disorder (ASD). PRT treatment sessions take place three times a week at the Yale Child Study Center over 16 weeks, and each visit lasts about 1.5 hours. These sessions are play-based, and the PRT team selects games, crafts, and other activities to match the child’s interests while working on social engagement and communication skills. The study requires a successful fMRI before beginning PRT. Before attempting the scan, a phone screener is required to determine the child’s eligibility and answer any questions parents might have. To learn more about this study, contact Emilio Gray (emilio.gray@yale.edu). | 4 to 9 years | 16 weeks of play-based therapy, fMRI, questionnaires, clinical evaluation
| up to $100 | Ventola Lab | Emilio Gray |
Brain Imaging Study of Emotion Regulation in Children | If you have a child who is 5 to 15 years old and has disruptive behaviors or has NO disruptive behaviors (such as anger, irritability, or aggression), they may be eligible to participate in a free and confidential study that examines your child’s social and emotional skills. This research will lead to new ways of understanding how children processes and regulate their emotions. The study will require two visits. At each visit you and your child will complete questionnaires, and your child will participate in an fMRI scan. Functional magnetic resonance imaging (fMRI) is a technique for measuring and mapping brain activity that is noninvasive and safe. You will also receive a free psychoeducational assessment describing your child’s social and emotional development. The study is conducted at the Yale Child Study Center by caring and supportive research staff. | 5 to 15 years | questionnaires and fMRI | up to $100 | Ibrahim Lab | emotion@yale.edu |
Autism Biomarkers Consortium for Clinical Trials | The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) is a research study to understand how to better measure social skills in school-age autistic children. We are currently recruiting both non-autistic children and children with a diagnosis of autism between the ages of 6 and 11 years old. A diagnostic and cognitive evaluation is provided to all participants at no cost and participants will be compensated up to $300. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 6 to 11 years | questionnaires, EEG, eye-tracking, clinical evaluation | up to $300 | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Stem Cell Study in Autism | You and your child are invited to participate in a study conducted by Flora Vaccarino, M.D. and colleagues at the Yale Child Study Center. The purpose of this study is to identify factors that influence brain cell development and function in individuals with Autism Spectrum Disorders. We are focusing on how young brain cells (known as “neuronal stem cells”) turn into mature cells (such as “neurons and glia”) and how they all function. | 6 years and up | - | up to $150 | Program in Neurodevelopment & Regeneration | flora.vaccarino@yale.edu
livia.tomasini@yale.edu |
Reading Patterns Explored Across Tasks (RePEAT) | The study goal is to identify how children learn language and reading skills both when they are well poised to do so and when they are struggling. We hope to identify the brain mechanisms underlying this learning and isolate what might indicate that a child is especially ready to learn to read. | 7 to 13 years | Behavioral testing, questionaires, MRI scan, fNIRS/EEG | Up to $250 | RePEAT Project Form | 203-785-2381, haskinsreading@yale.edu
|
Multi-level mechanisms and predictors of chronic irritability | Our research study wants to see how the brain and social and emotional factors help us predict irritability and its changes over two years. | 8 to 13 years | We are looking at irritability and frustration utilizing various procedures, e.g. fMRI (functional Magnetic Resonance Imaging), measuring physiological data (e.g. heart rate), questionnaires, and interviews. | up to $650 | YAY Lab
| call 203-479-0276
affectiveyouth@yale.edu |
Development of a Scale to Assess Suicide Thoughts and Behaviors among Preteens | Our study is creating a new survey to understand thoughts of self-harm in young children. Your insights will help shape how we address this growing concern. It’s important to note, your child does not need to experience thoughts of self-harm to participate. | 9 to 12 years | Two appointments, approximately 30 minutes each, where both parent and child complete questionnaires. | a total of $100 in gift cards ($50 per visit) | Anxiety and Mood Disorders Program | anxiety.csc@yale.edu or 203-737-4644
|
Neurofeedback from the supplementary motor area for Tourette Syndrome | Does your child have chronic tics or Tourette Syndrome? If your child is 10-16 years old with chronic tics, they may be eligible to receive neurofeedback treatment. We use a form of neurofeedback that involves monitoring brain activity via fMRI. The purpose of this study is to determine if our neurofeedback intervention can reduce tic symptoms and improve our understanding of Tourette Syndrome. Participation can result in compensation up to $880. If you have any further questions or concerns, please contact us at Hampson.lab@yale.edu, or (203)-737-6055. Study Sponsors: National Institute of Mental Health, Department of Human Health Services. HIC#2000033043 | 10 to 16 years | fMRI | up to $880 | Trial Website | call (203)-737-6055
Hampson.lab@yale.edu |
A multi-site feasibility clinical trial of Retraining and Control Therapy (ReACT)
| Yale Child Neurology and Yale Child Study Center are conducting a multi-site research study to examine the effects of two commonly used treatments for improving Functional Neurological Disorder (FND) symptoms, specifically Functional Seizures (FS). | 11 to 18 years | Cognitive Behavioral Therapy (CBT) based treatments are the standard of care for treating pediatric patients with FND symptoms. This study uses two different CBT-based therapies to assess FND treatment outcomes. If you choose, you can undergo the therapy to which you were not randomized to at the end of the study. | up to $250 | FND Study | call 203-479-0316
fndstudy@yale.edu |
Comprehensive Therapy for Irritability and Aggression (CTIA) in Autistic Adolescents | The Sukhodolsky Lab is seeking adolescents ages 12 to 19 who have been diagnosed with autism spectrum disorder (ASD) and have elevated levels of irritability to take part in a free and confidential study. Irritability and/or disruptive behaviors may include anger outbursts, temper tantrums, noncompliance, being easily frustrated, physical behaviors, difficulty following directions, and other similarly challenging behaviors. The purpose of this study is to test a novel psychosocial intervention for irritability and aggression in autism (CTIA) in comparison to a supportive psychotherapy control condition. We want to see if CTIA helps reduce irritability and aggressive behavior in adolescents with ASD. Participation involves completing 15 weeks of therapy, which may be conducted in-person at the Yale Child Study Center in New Haven, CT, or remotely by telehealth. Parents and adolescents also complete questionnaires and interviews about symptoms and behaviors before, during, and after treatment. The study provides a comprehensive assessment of autism, including IQ and adaptive function, and treatment for irritability at no cost to families. Families receive up to $250 for participation. Click here to learn more https://medicine.yale.edu/lab/sukhodolsky/ or contact Sydney Anderson at sydeny.anderson@yale.edu or (203) 737-7662. | 12 to 19 years | 15 weeks of therapy (remote or in person), interviews, questionnaires | up to $250 | Sukhodolsky Lab | call (203) 737-7662
sydney.anderson@yale.edu |
EEG study in Adolescents with Autism | This project studies how teens interact with peers in a computer game and in everyday life. Participation includes one or two visits to our lab where families will talk to a clinician, complete questionnaires, and teens will do computer activities while their brain waves are recorded with an electroencephalogram (EEG). We are currently recruiting teens between 13 and 17 years old. Participants will receive a clinical evaluation, assessment report, and compensation of $70. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 13 to 17 years | questionnaires, EEG, eye-tracking, clinical evaluation
| 70 | McPartland Lab | call 203-737-3439
autism@yale.edu |
Online Mental Health Intervention for Adolescents on the Waiting List for Mental Health Services | We are currently recruiting adolescents seeking outpatient services at YCSC for a study testing an online mental health intervention conducted while they are on the waiting list. The online mental health intervention is designed to teach coping and emotion regulation skills for adolescents struggling with mental health symptoms. This study will help us better understand how to best implement an online intervention for adolescents on the waiting list. We are recruiting any adolescent aged 13-17 years on the waiting list for services if they are not currently receiving treatment for the same problem elsewhere. Participants must have access to a mobile device. Participation is completely online. Adolescents will answer questions on their mobile phone or tablet and engage with the online intervention for 20-30 minutes. Then, adolescents will participate in either a focus group or individual interview lasting 60-90 minutes to assess their experience with the intervention. Parents will be contacted before adolescent participation for consent and answer any questions they may have. To learn more about our study, please contact accesslab@yale.edu. This study has been approved by the Yale IRB (HIC #2000035977). | 13 to 17 years | Self-report questionnaires, engaging with an online intervention for mental health, focus groups. | 60 | ACCESS Lab | accesslab@yale.edu |
Reducing Adolescent Suicide Risk in Treatment-Resistant Depression | Yale is conducting a study to examine the safety, efficacy, response predictors, and post treatment trajectory of adolescents (13–17 years old) with treatment-resistant depression and high suicide risk following a conservative repeat dosing Ketamine infusion paradigm compared to an active control, Midazolam. Those who are randomized to Midazolam and remain ill have the option to cross-over to Ketamine in the open phase. All participants will be followed closely for 4 months post-treatment and treated with standard of care depression treatment (medication management and cognitive behavioral therapy). Brain-based predictors of anti-suicidal responses will be assessed via connectome predictive modeling and examining functional brain circuits via fMRI before and after treatment. Compensation is up to $320. To learn more about this study, contact Brooke Rivera, Clinical Coordinator, Yale Pediatric Depression Lab at (203)785-7880 or email PediDepression@yale.edu. | 13 to 17 years | Ketamine infusion, standard of care depression treatment | up to &320 | Bloch Lab | call (203)785-7880
PediDepression@yale.edu |
Parent-Based Treatment for Adolescent Anxiety
| This study aims to test the efficacy of a parent-only treatment for anxiety disorders in teens, SPACE (Supportive Parenting for Anxious Childhood Emotions), by comparing it to another parent-based approach, Parent Education and Support (PES). Teens 14-17 years old with anxiety disorders and their parents may be eligible to participate. Parents and teens complete three assessments involving diagnostic interviews and/or questionnaires. Parents only are randomly assigned to receive 12 weeks of either SPACE or PES. | 14 to 17 | Teens and parents complete questionnaires and diagnostic interviews. Parents only attend 12 weeks of therapy for their teen's anxiety. | Up to $100 | Anxiety and Mood Disorders Program | anxiety.csc@yale.edu
203-737-4644
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Perspectives of Life and Daily Thoughts (Project PLAD)
| The purpose of this study is to examine what perpetuates suicidal thoughts and behaviors (STBs), and identify ways to mitigate it. We aim to achieve this through a longitudinal study assessing future life-oriented (FLO) thinking and clinically-relevant correlates among teens (15-19) and their parents. Participation includes: self-report surveys and observation of parent-child interactions during a zoom research visit, brief micro-surveys via smartphones over 42 days, and stress-hormone collection from nail samples from teens. | 15 to 19 | Procedures include: zoom study visit with individual tasks, observed parent-child interactions and self-report questionnaires, brief micro-surveys through the phone based app Metricwire, and a follow-up zoom session with self-report surveys and observed parent-child interactions. | Up to $300 | Cha Lab | project.plad@yale.edu
203-764-7210
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Neurodevelopmental Biomarkers of Late Diagnosis in Autism | The Sukhodolsky Lab is seeking volunteers to participate in a research study to help to improve access to autism diagnosis. Autistic people aged 16-39 years are invited to answer questions and complete surveys. These activities can be done out loud, by writing, online or using augmentative/alternative communication. The purpose of the study is to advance the knowledge of the autistic experience. We are aiming to learn about why some people get an autism diagnosis when they are young, and other people get an autism diagnosis when they are teens or adults. Participation involves 1-2 visits, and participants will be compensated up to $225 for participating, and results of study assessments can be shared with participants free of charge. In addition to the 1-2 visits, participants may also be invited to complete optional activities at other visits such as: interviews (up to 1 hour) and brain scans using MRI (up to 2-3 hours). For more information our if you are interested in participating, please contact Ms. Emma Simons at sukhodolsky.lab@yale.edu or 203-737-7664. | 16 to 39 years | 1-2 visits, interviews (up to 1 hour), brain scans using MRI (up to 2-3 hours). | up to $225 | Sukhodolsky Lab | call 203-737-7664
sukhodolsky.lab@yale.edu |
Teen Brain Imaging Study | The Cho Lab at Yale is running a research study to examine how the brain supports cognition and motivation in teenagers, ages 13-17 years old. We would like to understand how these brain changes contribute to depression and schizophrenia or psychosis in teenagers. Typically developing teenagers, teenagers who have depression or teenagers who have schizophrenia/psychosis may be eligible to participate. The study is confidential, and teenagers are compensated for their participation. For further details please email ChoLab@yale.edu or call 203-815-9874. | 13 to 17 years | Clinical assessments, MRI, IQ testing | Up to &650 | Cho Lab | call 203-815-9874
ChoLab@yale.edu |
Stem Cell Study in Tourette's Disorder | You and your child are invited to participate in a study conducted by Flora Vaccarino, M.D. and colleagues at the Yale Child Study Center. The purpose of this study is to identify factors that influence brain cell development and function in individuals with Autism Spectrum Disorders and Tourette Syndrome. We are focusing on how young brain cells (known as “neuronal stem cells”) turn into mature cells (such as “neurons and glia”) and how they all function. | 16 years and up | Saliva, blood draw, clinical assessments. | $100 for samples and $100 for clinical assessments | Program in Neurodevelopment & Regeneration | flora.vaccarino@yale.edu
livia.tomasini@yale.edu |
Auditory Study in Autism | This study investigates how the brain processes sounds, and why sometimes the same sounds can feel too loud or too quiet. Participation includes a one-time visit to the lab where brain activity is measured using an electroencephalogram (EEG) in response to various sounds. In addition, participants will talk to a clinician, complete questionnaires, and answer online daily questions at home throughout the following week. We are recruiting adults with and without autism between the ages of 18-40 years old. Participants will be compensated up to $75 for their time. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | questionnaires, EEG, eye-tracking, clinical evaluation, online survey | up to $65 | McPartland Lab | call 203-737-3439
autism@yale.edu |
The IRIS Study | The IRIS clinical trial is evaluating an oral investigational medication, ML-004, to see if it may help alleviate some of the symptoms that interfere with communication in those with autism spectrum disorder (ASD). Participants may be able to take part in the clinical trial if they are between the ages of 18 and 45 years old, have a diagnosis of autism spectrum disorder (ASD), have a clinical trial/care partner willing to assist during the trial. The clinical trial/care partner is someone who lives with or has frequent contact with the clinical trial participant (parent, spouse, friend, etc.) and is willing and able to provide information about the participant and attend some trial visits. The clinical trial team will discuss additional eligibility criteria with you. | 18 to 45 years | medication, office visits | - | Maplight | marcia.questel@yale.edu or morgan.patterson@yale.edu |
Transcranial Magnetic Stimulation (TMS) for Depression in Autism | This study will evaluate the effects of Transcranial Magnetic Stimulation (TMS), a type of noninvasive brain stimulation for potentially treating depression in autistic individuals. TMS is a therapy that has been approved for conditions like depression, anxious depression, and obsessive-compulsive disorder. Depression is common in autism so there is a need to better understand why autistic individuals have higher rates of depression than neurotypical individuals. In addition, many autistic individuals with depression may not respond to standard antidepressant medications. In our study, we conduct clinical assessments, then EEG and eye tracking experiments before and after TMS. Study participants will be compensated up to $250. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | clinical assessments, TMS, EEG and eye tracking experiments | up to &250 | McPartland Lab | call 203-737-3439
autism@yale.edu |
Transcranial Magnetic Stimulation (TMS) Study | This study will evaluate the effects of repetitive Transcranial Magnetic Stimulation (rTMS), a type of noninvasive brain stimulation. TMS is a therapy that has been approved for depression and obsessive-compulsive disorder and we are looking to see if it can also help autistic people. This method uses magnetic waves to influence brain activity. Participation includes two visits that involve answering questions and solving puzzles, as well as a recording of brain waves (using EEG) and watching videos on a computer screen. Compensation is $100 per visit. To learn more about the study or to participate, please call us at 203-737-3439 or email our team at autism@yale.edu. | 18 to 40 years | clinical assessments, TMS, EEG and eye tracking experiments | $100 per visit | McPartland Lab | call (203) 737-3439
autism@yale.edu |
Psychological Risk on Mother Infant Study (PROMISE) | Seeking First-Time Expecting Mothers for Research Study with $500 compensation!
We are interested in how the maternal brain changes over pregnancy and postpartum, the role of maternal factors in shaping such changes, and the impact of those changes on parenting and child development.
Click the link if you are interested: https://yalesurvey.ca1.qualtrics.com/.../SV_6FP1gxSi4L0rBeC | 18 to 45 years | EEG, questionnaires, interviews, and caregiving tasks | 500 | BABL Lab | call 203-689-2831
promise@yale.edu |
Misophonia Genetics Study | The purpose of the Misophonia Genetics Study is to identify the genetic factors that cause misophonia (a condition in which certain sounds trigger an intense emotional or physiological response) using a family-based approach. This will greatly contribute to our understanding of misophonia and may help develop new therapies in the future. This study requires participation from a child and both biological parents. Families will be compensated with a $75 Amazon gift card for the family. | - | saliva collection (child and both parents), questionnaires | $25 Amazon gift card | Misophonia Genetics Study | misophonia@yale.edu |
TABS Study | Your family has been invited to be part of a study of families in which an individual has trichotillomania or other body focused repetitive behavior (BFRB). Although it is well known that genetic factors play a role in causing BFRBs, the responsible genes have not yet been discovered. Recent dramatic advances in genetic techniques hold out the promise that we may soon be able to identify such risk-conferring genes. The purpose of this study is to identify the genetic factors that cause trichotillomania and other BFRBs using a family-based approach. This will greatly contribute to our understanding of these conditions and may help develop new therapies in the future. This study requires participation from an individual impacted by trichotillomania or other BFRB and both biological parents. The study can be done in-person or remotely. We are not able to offer you a report of your genetic results because our studies are performed as research. Our research lab does not offer any treatment. | - | Saliva sample (child and both parents), questionnaire | - | TABS Study | tabsstudy@yale.edu |
UPWARDS Study | The purpose of the UPWARDS Study is to develop a better approach to identify pregnant individuals who are having difficulty with their emotional wellbeing and may need extra help or support during and after pregnancy. We’d love to have you join and play an important role in our study. | - | passive data collection, questionnaires | up to $190 | UPWARDS Study | Kieran.ODonnell@yale.edu |
Valbenazine for the Treatment of Trichotillomania in Adults | If you are an adult with trichotillomania, you may be eligible to participate in an in-person research study run by the Yale School of Medicine. This study will examine the efficacy of Valbenazine for the treatment of trichotillomania. Valbenazine is a dopamine-depleting agent that is currently FDA-approved for tardive dyskinesia and has a relatively safe side-effect profile in initial trials. While enrolled in the trial, you will receive regular psychiatric and medical assessments of symptoms at no cost. Additionally, you will receive a stipend of up to $590 over the course of 26 weeks for your participation. In-person visits occur about every two weeks and are held at 350 George St. New Haven, CT 06511. If you are interested in the trial or wish to learn more, please do not hesitate to contact us by phone at (203)785-7880 or email at blochresearch@yale.edu if you have any questions about the trial. | - | medication, psychiatric and medical assessments | stipend of up to $590 over the course of 26 weeks | Bloch Lab | call (203)785-7880
blochresearch@yale.edu |
Yale CDD Study | Does your child have childhood disintegrative disorder (CDD) or autism spectrum disorder (ASD) with a history of normal development followed by a regression (loss of skills) around 3 years of age or later? We invite you to participate in the Yale CDD study. | - | Forms, questionnaires, saliva samples | - | CDD Study | yale.cdd@yale.edu
(203) 868-0653 |