2018
Course, outcome and diagnosis stability of early-onset schizophrenia in Yunnan Province, China-a three years follow-up study
Kang C, Zhou H, Yang J, Yang R, Sun N, Wang S, Yang C, Han D, Srihari VH. Course, outcome and diagnosis stability of early-onset schizophrenia in Yunnan Province, China-a three years follow-up study. Psychiatry Research 2018, 271: 144-149. PMID: 30472510, DOI: 10.1016/j.psychres.2018.11.013.Peer-Reviewed Original ResearchConceptsEarly-onset schizophreniaICD-10 diagnosisDiagnostic stabilityMini International Neuropsychiatric InterviewFirst Affiliated HospitalInternational Neuropsychiatric InterviewKunming Medical UniversityHigh diagnostic stabilityDepartment of PsychiatryPoor outcomeAffiliated HospitalNeuropsychiatric InterviewInternational ClassificationBetter outcomesModerate outcomeMedical UniversityGlobal functioningICD-10Psychosocial outcomesPatientsSchizophreniaDiagnosis stabilityDiagnosisOutcomesHospitalAn Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector.
Murphy SM, Kucukgoncu S, Bao Y, Li F, Tek C, Breitborde NJK, Guloksuz S, Phutane VH, Ozkan B, Pollard JM, Cahill JD, Woods SW, Cole RA, Schoenbaum M, Srihari VH. An Economic Evaluation of Coordinated Specialty Care (CSC) Services for First-Episode Psychosis in the U.S. Public Sector. The Journal Of Mental Health Policy And Economics 2018, 21: 123-130. PMID: 30530872, PMCID: PMC6314808.Peer-Reviewed Original ResearchConceptsSpecialty care servicesPatient costsEarly intervention servicesUsual treatmentSchizophrenia spectrum disordersMonth 12Economic evaluationCare servicesSTEP participantsCommunity mental health centerThird-party payer perspectiveIntervention servicesFirst-episode servicesMonths post randomizationHealthcare service utilizationMental health centersU.S. public sectorTeam-based careCost-offset analysisEligible patientsThird-party payersAntipsychotic exposureED visitsMonth 6Episode psychosis
2013
Automatic Auditory Processing Deficits in Schizophrenia and Clinical High-Risk Patients: Forecasting Psychosis Risk with Mismatch Negativity
Perez VB, Woods SW, Roach BJ, Ford JM, McGlashan TH, Srihari VH, Mathalon DH. Automatic Auditory Processing Deficits in Schizophrenia and Clinical High-Risk Patients: Forecasting Psychosis Risk with Mismatch Negativity. Biological Psychiatry 2013, 75: 459-469. PMID: 24050720, PMCID: PMC4028131, DOI: 10.1016/j.biopsych.2013.07.038.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCase-Control StudiesDisease ProgressionEvoked Potentials, AuditoryFemaleHumansMalePredictive Value of TestsPsychiatric Status Rating ScalesPsychotic DisordersRiskSchizophreniaYoung AdultConceptsCHR patientsHealthy control subjectsPsychosis onsetControl subjectsClinical high-risk patientsEarly illness schizophrenia patientsPsychosis riskClinical high-risk individualsHigh-risk patientsThird of patientsHigh-risk individualsCurrent clinical criteriaAuditory processing deficitsMismatch negativityNonclinical measuresAuditory devianceCox regressionClinical criteriaUnnecessary treatmentHigh riskCHR convertersPatientsPsychotic disordersSchizophrenia patientsPreventive interventionsChapter 10 Early auditory gamma-band responses in patients at clinical high risk for schizophrenia
Perez VB, Roach BJ, Woods SW, Srihari VH, McGlashan TH, Ford JM, Mathalon DH. Chapter 10 Early auditory gamma-band responses in patients at clinical high risk for schizophrenia. Supplements To Clinical Neurophysiology 2013, 62: 147-162. PMID: 24053038, PMCID: PMC4120874, DOI: 10.1016/b978-0-7020-5307-8.00010-7.Peer-Reviewed Original ResearchConceptsClinical high riskPhase-locking factorGamma-band responseAuditory gamma-band responsesCHR patientsHigh riskSchizophrenia patientsChronic schizophrenia patientsNMDA glutamate receptorsYounger schizophrenia patientsTransient gamma-band responseTrend-level reductionsNeurotransmission abnormalitiesGamma-band oscillationsYounger patientsIllness onsetProdromal symptomsPhase synchronyProdromal periodHealthy controlsPsychosis onsetPatientsPsychotic disordersCHR groupElectroencephalographic studies
2012
Self-determination and first-episode psychosis: Associations with symptomatology, social and vocational functioning, and quality of life
Breitborde NJ, Kleinlein P, Srihari VH. Self-determination and first-episode psychosis: Associations with symptomatology, social and vocational functioning, and quality of life. Schizophrenia Research 2012, 137: 132-136. PMID: 22445463, PMCID: PMC3351585, DOI: 10.1016/j.schres.2012.02.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildFemaleHumansMaleOccupationsPersonal AutonomyPersonal SatisfactionPsychiatric Status Rating ScalesPsychotic DisordersQuality of LifeSocial BehaviorConceptsSelf-determination theoryBasic psychological needsNeed satisfactionPsychological needsFirst-episode psychosisNeed of relatednessSample of individualsEarly intervention servicesVocational functioningLess satisfactionIntervention servicesSatisfactionCurrent studyPsychosisIndividualsModest associationBeingQuality of lifeFunctioningMotivationSymptomatologyAssociationNeedDomainRelatedness
2011
Insomnia is frequent in schizophrenia and associated with night eating and obesity
Palmese LB, DeGeorge PC, Ratliff JC, Srihari VH, Wexler BE, Krystal AD, Tek C. Insomnia is frequent in schizophrenia and associated with night eating and obesity. Schizophrenia Research 2011, 133: 238-243. PMID: 21856129, PMCID: PMC5581545, DOI: 10.1016/j.schres.2011.07.030.Peer-Reviewed Original ResearchConceptsBody mass indexQuality of lifeSleep difficultiesMass indexClinical insomniaSevere insomniaNight eatingPoor sleepPsychiatric symptomsTypes of antipsychoticsPrevalence of insomniaRelationship of sleepProminent clinical concernBrief cognitive assessmentIndependent predictorsPoint prevalenceClinical variablesClinical careSleep patternsSchizoaffective disorderClinical concernInsomniaLow qualityWeight gainSchizophrenia