2019
Early intervention service for first episode psychosis in Modena, Northern Italy: The first hundred cases
Ferrara M, Tedeschini E, Baccari F, Musella V, Vacca F, Mazzi F, Ferri M, Srihari V, Starace F, Group F. Early intervention service for first episode psychosis in Modena, Northern Italy: The first hundred cases. Early Intervention In Psychiatry 2019, 13: 1011-1017. PMID: 30672134, DOI: 10.1111/eip.12788.Peer-Reviewed Original ResearchConceptsEarly intervention servicesClinical improvementMedian ageIntervention servicesCommunity mental health centerCommunity outpatient servicesPsychiatric hospital unitMeaningful clinical improvementFirst-episode psychosisModel of careNon-affective psychosisNation Outcome ScalesMental health centersHigher median ageEarly detection effortsRefinement of treatmentMain referralsPharmacological consultationYounger patientsUntreated psychosisOutcome ScaleGeneral practitionersEpisode psychosisHealth centersOutpatient services
2015
Too Late and Too Little: Narratives of Treatment Disconnect in Early Psychosis
van Schalkwyk GI, Davidson L, Srihari V. Too Late and Too Little: Narratives of Treatment Disconnect in Early Psychosis. Psychiatric Quarterly 2015, 86: 521-532. PMID: 25663602, PMCID: PMC5576358, DOI: 10.1007/s11126-015-9348-4.Peer-Reviewed Original ResearchConceptsFirst episode psychosis programLong-term outcomesSpecialized treatment servicesOnset of psychosisInitial contactSpecialized servicesYounger patientsSignificant morbidityPsychosis programPatient preferencesEarly treatmentEffective treatmentEarly psychosisPsychiatric careTreatment experienceTreatment prioritiesPsychotic disordersTreatment servicesPatientsInductive thematic analysisFurther treatmentTreatmentDisproportionate improvementBehavioral changesCritical period
2014
Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study
Srihari VH, Tek C, Pollard J, Zimmet S, Keat J, Cahill JD, Kucukgoncu S, Walsh BC, Li F, Gueorguieva R, Levine N, Mesholam-Gately RI, Friedman-Yakoobian M, Seidman LJ, Keshavan MS, McGlashan TH, Woods SW. Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study. BMC Psychiatry 2014, 14: 335. PMID: 25471062, PMCID: PMC4262386, DOI: 10.1186/s12888-014-0335-3.Peer-Reviewed Original ResearchConceptsEarly detectionEarly outcomesGeographic catchmentTIPS studyYounger patientsAppropriate patientsUntreated psychosisPsychosis onsetEffective treatmentCare providersPsychotic symptomsPublic education campaignsPsychotic disordersHelp-seeking behaviorSecondary aimComprehensive interventionPatientsIntervention servicesDUPEducation campaignsOutcomesSocial marketing approachPrimary aimTreatmentFES
2013
Chapter 10 Early auditory gamma-band responses in patients at clinical high risk for schizophrenia
Perez VB, Roach BJ, Woods SW, Srihari VH, McGlashan TH, Ford JM, Mathalon DH. Chapter 10 Early auditory gamma-band responses in patients at clinical high risk for schizophrenia. Supplements To Clinical Neurophysiology 2013, 62: 147-162. PMID: 24053038, PMCID: PMC4120874, DOI: 10.1016/b978-0-7020-5307-8.00010-7.Peer-Reviewed Original ResearchConceptsClinical high riskPhase-locking factorGamma-band responseAuditory gamma-band responsesCHR patientsHigh riskSchizophrenia patientsChronic schizophrenia patientsNMDA glutamate receptorsYounger schizophrenia patientsTransient gamma-band responseTrend-level reductionsNeurotransmission abnormalitiesGamma-band oscillationsYounger patientsIllness onsetProdromal symptomsPhase synchronyProdromal periodHealthy controlsPsychosis onsetPatientsPsychotic disordersCHR groupElectroencephalographic studies
2009
Public-academic partnerships: early intervention for psychotic disorders in a community mental health center.
Srihari VH, Breitborde NJ, Pollard J, Tek C, Hyman L, Frisman LK, McGlashan TH, Jacobs S, Woods SW. Public-academic partnerships: early intervention for psychotic disorders in a community mental health center. Psychiatric Services 2009, 60: 1426-8. PMID: 19880454, PMCID: PMC4469899, DOI: 10.1176/appi.ps.60.11.1426.Peer-Reviewed Original ResearchConceptsMental health centersEarly interventionHealth centersConnecticut Mental Health CenterCommunity mental health centerLong-term outcomesEarly intervention servicesYounger patientsUntreated illnessPsychotic illnessPsychotic disordersAddiction servicesSpecialized treatmentMental healthInterventionConnecticut DepartmentIllnessPatientsPsychosisCognitive Behavior Therapy for Early Psychosis: A Comprehensive Review of Individual vs. Group Treatment Studies
Saksa JR, Cohen SJ, Srihari VH, Woods SW. Cognitive Behavior Therapy for Early Psychosis: A Comprehensive Review of Individual vs. Group Treatment Studies. International Journal Of Group Psychotherapy 2009, 59: 357-383. PMID: 19548785, DOI: 10.1521/ijgp.2009.59.3.357.Peer-Reviewed Original ResearchConceptsGroup cognitive behavior therapyCognitive behavior therapyEarly psychosisEarly casesModest treatment benefitsGroup of patientsBehavior therapyYounger patientsGroup treatment studyTreatment benefitPatient uncertaintyEffective modalityTreatment studiesPsychosisPatientsTherapyOutcomesRecent studiesCurrent studyIllnessComprehensive review