2024
The Italian adaptation of the Mini‐SIPS, a tool for early detection of individuals at clinical high risk and first episode of psychosis: A preliminary study of implementation in an Italian FEP program
Ferrara M, Basaldella M, Vacca F, Woods S, Walsh B, Cannon T, Srihari V, Grassi L. The Italian adaptation of the Mini‐SIPS, a tool for early detection of individuals at clinical high risk and first episode of psychosis: A preliminary study of implementation in an Italian FEP program. Early Intervention In Psychiatry 2024 PMID: 38769052, DOI: 10.1111/eip.13548.Peer-Reviewed Original ResearchClinical high riskFirst-episode psychosisDSM-5-Attenuated Psychosis SyndromeItalian adaptationPsychosis syndromeDSM-5FEP programsEarly stages of psychosisItalian versionFirst-episode psychosis servicesFull-blown psychosisStages of psychosisEpisode of psychosisClinical structured interviewEpisode psychosisEstablished psychosisTrained psychologistsPsychiatric historyPsychosisPsychosis servicesHigh riskStructured interviewsClinical settingEarly detection of individualsAssess validityRole of Early Psychosis Detection in the Relationship Between Personal Income and Duration of Untreated Psychosis
Venkataraman S, Hazan H, Li F, Ferrara M, Harper A, Ma J, Shah J, Musket C, Levine N, Keshavan M, Srihari V. Role of Early Psychosis Detection in the Relationship Between Personal Income and Duration of Untreated Psychosis. Psychiatric Services 2024, 75: 427-433. PMID: 38204369, DOI: 10.1176/appi.ps.20230239.Peer-Reviewed Original ResearchDuration of untreated psychosisFirst-episode psychosis servicesFirst-episode psychosisEarly psychosis detectionLow personal incomeSocioeconomic statusUntreated psychosisOutcome of first-episode psychosisLength of duration of untreated psychosisEffectiveness of early detectionSpecialty care clinicsProlonged duration of untreated psychosisReduce duration of untreated psychosisEffects of ageLow socioeconomic statusPersonal incomeIndicators of disparitiesEarly detection effortsAssociated with younger ageYears of educationSES indicatorsCare clinicsEarly detectionBlack raceHierarchical regression
2023
The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service
Ferrara M, Guloksuz S, Hazan H, Li F, Tek C, Sykes L, Riley S, Keshavan M, Srihari V. The effect of duration of untreated psychosis (DUP) on the risk for hospitalization after admission to a first episode service. Schizophrenia Research 2023, 260: 198-204. PMID: 37688984, DOI: 10.1016/j.schres.2023.08.005.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesLength of stayUntreated psychosisPsychiatric hospitalizationFirst-episode servicesDuration of hospitalizationIncidence rate ratiosNon-affective psychosisNew Haven areaPoisson regression modelsPatient characteristicsHospitalization ratesRecent onsetMedical recordsHospitalizationEffect of durationNegative binomial regressionSpecialized treatmentPsychosisRate ratioBinomial regressionAdmissionDUPEnrollmentFirst yearSampling from different populations: Sociodemographic, clinical, and functional differences between samples of first episode psychosis individuals and clinical high-risk individuals who progressed to psychosis
Hagler M, Ferrara M, Yoviene Sykes L, Li F, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Perkins D, Mathalon D, Seidman L, Tsuang M, Walker E, Powers A, Allen A, Srihari V, Woods S. Sampling from different populations: Sociodemographic, clinical, and functional differences between samples of first episode psychosis individuals and clinical high-risk individuals who progressed to psychosis. Schizophrenia Research 2023, 255: 239-245. PMID: 37028205, PMCID: PMC10207144, DOI: 10.1016/j.schres.2023.03.047.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesClinical high riskClinical high-risk individualsEarly detectionFirst-episode psychosis individualsRecent psychiatric hospitalizationCourse of illnessHigh-risk individualsAttenuated positive symptomsCHR researchGeographic catchmentSyndromal psychosisPsychosis individualsPsychiatric hospitalizationEarly intervention effortsHigh riskPsychosis servicesPositive symptomsGlobal functioningClinical resourcesProtective factorsDifferent populationsFE participantsGeneralizability of findingsFES program
2022
Reducing Delay From Referral to Admission at a U.S. First-Episode Psychosis Service: A Quality Improvement Initiative
Ferrara M, Gallagher K, Yoviene Sykes LA, Markovich P, Li F, Pollard JM, Imetovski S, Cahill J, Guloksuz S, Srihari VH. Reducing Delay From Referral to Admission at a U.S. First-Episode Psychosis Service: A Quality Improvement Initiative. Psychiatric Services 2022, 73: 1416-1419. PMID: 35652190, PMCID: PMC9715806, DOI: 10.1176/appi.ps.202100374.Peer-Reviewed Original ResearchConceptsFirst-episode psychosis servicesConfirmation of eligibilityEarly detection campaignsProportion of admissionsSpecialty care servicesQuality improvement interventionsQuality improvement initiativesLonger DUPMedian delayPoor outcomeUntreated psychosisTreatment accessPsychosis onsetPsychosis servicesCSC servicesCare servicesImprovement interventionsAdmissionImprovement initiativesDetection campaignsInterventionGreater vulnerabilityReferralPsychosisTiming of cannabis exposure relative to prodrome and psychosis onset in a community-based first episode psychosis sample
Kline ER, Ferrara M, Li F, D'Souza DC, Keshavan M, Srihari VH. Timing of cannabis exposure relative to prodrome and psychosis onset in a community-based first episode psychosis sample. Journal Of Psychiatric Research 2022, 147: 248-253. PMID: 35066293, PMCID: PMC8882157, DOI: 10.1016/j.jpsychires.2022.01.039.Peer-Reviewed Original ResearchConceptsCannabis exposurePublic health significancePsychosis onsetPsychotic disordersHealth significanceFirst-episode psychosis samplePsychosis sampleFirst exposureFirst-episode psychosis servicesWorse premorbid functioningAdverse prognostic factorAssociation of ageImpact of cannabisPsychosis PreventionSymptom onsetPrognostic factorsOverall incidenceEarly psychosis sampleConsecutive admissionsOverall burdenPsychotic illnessPsychosis servicesPsychosis symptomsGreater severityYounger age
2021
Taking the next step: Improving care transitions from a first‐episode psychosis service
Gallagher K, Ferrara M, Pollard J, Sykes L, Li F, Imetovski S, Cahill J, Mathis W, Srihari VH. Taking the next step: Improving care transitions from a first‐episode psychosis service. Early Intervention In Psychiatry 2021, 16: 91-96. PMID: 35029048, DOI: 10.1111/eip.13127.Peer-Reviewed Original ResearchConceptsFirst-episode servicesQuality improvement approachQI approachExact testFirst-episode psychosis servicesUnknown treatment statusRecent-onset psychosisFisher's exact testDischarge planning processStudy-Act cyclesDischarge planningCare transitionsCare 3Onset psychosisDisposition planningPsychosis servicesTreatment statusFunctional gainsPatient engagementQI phasePlan-DoPatientsDisposition outcomesTransfer statusMonths