2023
Caution needed in ascribing subthreshold symptoms as autism spectrum disorder: Commentary on “autistic traits distribution in different psychiatric conditions: A cluster analysis on the basis of the adult autism subthreshold spectrum (AdAS SPECTRUM) questionnaire”
Bertelli M, Boniotti V, Bianco A, Vannucchi G, Buonaguro E, Micai M, Fatta L, Rossi M, Pecchini E, Bizzari V, Conte M, Lombardi G, Corti S, Scior K, Azeem M, Hassiotis A, Baghdadli A, Scattoni M, Salvador-Carulla L, Javed A, Munir K. Caution needed in ascribing subthreshold symptoms as autism spectrum disorder: Commentary on “autistic traits distribution in different psychiatric conditions: A cluster analysis on the basis of the adult autism subthreshold spectrum (AdAS SPECTRUM) questionnaire”. Psychiatry Research 2023, 331: 115617. PMID: 38043410, DOI: 10.1016/j.psychres.2023.115617.Peer-Reviewed Original ResearchAdultAutism Spectrum DisorderAutistic DisorderCluster AnalysisHumansSelf ReportSurveys and QuestionnairesGenomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study
Abdi M, Aliyev E, Trost B, Kohailan M, Aamer W, Syed N, Shaath R, Gandhi G, Engchuan W, Howe J, Thiruvahindrapuram B, Geng M, Whitney J, Syed A, Lakshmi J, Hussein S, Albashir N, Hussein A, Poggiolini I, Elhag S, Palaniswamy S, Kambouris M, de Fatima Janjua M, Tahir M, Nazeer A, Shahwar D, Azeem M, Mokrab Y, Aati N, Akil A, Scherer S, Kamal M, Fakhro K. Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study. Genome Medicine 2023, 15: 81. PMID: 37805537, PMCID: PMC10560429, DOI: 10.1186/s13073-023-01228-w.Peer-Reviewed Original ResearchMeSH KeywordsAutism Spectrum DisorderChildDNA Copy Number VariationsDNA, MitochondrialGenetic Predisposition to DiseaseGenomeGenomicsHumansQatarConceptsTandem repeat expansionsSingle nucleotide variantsGenetic architectureNovel ASD candidate genesWhole-genome sequencing dataMitochondrial DNA variantsASD candidate genesMulti-omics researchGenomic architectureRecessive variationMtDNA variantsCandidate genesDNA variantsSequencing dataRepeat expansionNumber variantsSNVs/indelsDe novoNon-consanguineous familyGenesGenetics guidelinesUnique resourcePathogenic variantsFamilyMedical Genetics guidelines
2020
Genetics of structural and functional brain changes in autism spectrum disorder
Hashem S, Nisar S, Bhat A, Yadav S, Azeem M, Bagga P, Fakhro K, Reddy R, Frenneaux M, Haris M. Genetics of structural and functional brain changes in autism spectrum disorder. Translational Psychiatry 2020, 10: 229. PMID: 32661244, PMCID: PMC7359361, DOI: 10.1038/s41398-020-00921-3.Peer-Reviewed Original ResearchConceptsASD patientsAutism spectrum disorderFunctional brain changesSpecific single nucleotide polymorphismsClinical managementIsolated disorderBrain changesSpectrum disorderTherapeutic interventionsFunctional changesNoninvasive imagingDisordersSingle nucleotide polymorphismsGenetic disordersPatientsRisk genesDevelopmental disordersSocial impairmentNeuropsychiatryASD diagnosisCommunicative behavior
2019
Association of genes with phenotype in autism spectrum disorder
Nisar S, Hashem S, Bhat A, Syed N, Yadav S, Azeem M, Uddin S, Bagga P, Reddy R, Haris M. Association of genes with phenotype in autism spectrum disorder. Aging 2019, 11: 10742-10770. PMID: 31744938, PMCID: PMC6914398, DOI: 10.18632/aging.102473.Peer-Reviewed Original ResearchMeSH KeywordsAutism Spectrum DisorderChildFemaleGenetic Association StudiesGenetic Predisposition to DiseaseHumansMalePhenotypeConceptsASD risk genesRisk genesNovel candidate genesAssociation of genesGene transcriptionGenetic pathwaysNeuronal activity modulationCandidate genesGenesGenetic variantsPathophysiology of ASDPathwayHeterogeneous neurodevelopmental disorderRegulation processesActivity modulationSynaptic plasticityNeurodevelopmental disordersTranscriptionIdentificationGeneticsPhenotypeRolePlasticityAutism spectrum disorderField of neuroscience