2024
BK polyomavirus DNAemia, allograft rejection, and de novo donor‐specific antibodies after lowering target tacrolimus levels in pediatric kidney transplant recipients
Huang H, Xiang Y, George R, Winterberg P, Serluco A, Liverman R, Yildirim I, Garro R. BK polyomavirus DNAemia, allograft rejection, and de novo donor‐specific antibodies after lowering target tacrolimus levels in pediatric kidney transplant recipients. Pediatric Transplantation 2024, 28: e14791. PMID: 38808701, DOI: 10.1111/petr.14791.Peer-Reviewed Original ResearchConceptsDe novo donor-specific antibodiesTarget tacrolimus levelsDevelopment of de novo donor-specific antibodiesBiopsy-proven rejectionDonor-specific antibodiesMonths post-KTTacrolimus levelsTime of transplantationPediatric KT recipientsBK polyomavirusBKV-DNAemiaPost-KTPost-intervention cohortAllograft rejectionRecipient ageKT recipientsKidney transplantationPediatric kidney transplant recipientsLow tacrolimus levelsReduction of immunosuppressionKaplan-Meier survival analysisYounger recipient ageIndividualized immunosuppressive regimensKidney transplant recipientsRetrospective chart review
2019
Sirolimus‐associated pericardial effusion with cardiac tamponade and interstitial pneumonitis in a hematopoietic stem cell transplant recipient
Joo SJ, Yildirim I, Stenger EO, Anderson EJ. Sirolimus‐associated pericardial effusion with cardiac tamponade and interstitial pneumonitis in a hematopoietic stem cell transplant recipient. Pediatric Transplantation 2019, 23: e13425. PMID: 31012209, DOI: 10.1111/petr.13425.Peer-Reviewed Original ResearchConceptsHSCT patientsCardiac tamponadeInterstitial pneumonitisPericardial effusionAllogeneic hematopoietic stem cell transplant patientsHematopoietic stem cell transplant recipientsHematopoietic stem cell transplant patientsStem cell transplant patientsStem cell transplant recipientsAllogeneic HSCT patientsCell transplant recipientsLife-threatening complicationsCell transplant patientsTreatment of graftInvasive fungal infectionsGVHD prophylaxisHost diseaseTransplant patientsTransplant recipientsSirolimus useRapamycin inhibitorsPotent immunosuppressantPatientsFungal infectionsMammalian target