2022
Association of Child Masking With COVID-19–Related Closures in US Childcare Programs
Murray TS, Malik AA, Shafiq M, Lee A, Harris C, Klotz M, Humphries JE, Patel KM, Wilkinson D, Yildirim I, Elharake JA, Diaz R, Reyes C, Omer SB, Gilliam WS. Association of Child Masking With COVID-19–Related Closures in US Childcare Programs. JAMA Network Open 2022, 5: e2141227. PMID: 35084484, PMCID: PMC8796014, DOI: 10.1001/jamanetworkopen.2021.41227.Peer-Reviewed Original ResearchConceptsCOVID-19 casesLower riskImportant public health policy implicationsCOVID-19-related closuresPublic health policy implicationsChildren 2 yearsElectronic survey studyCenter-based childcare programsHealth policy implicationsSARS-CoV-2Survey studyChildcare professionalsMAIN OUTCOMEProgram closureHealth policyStudy periodRobust SEsBaselineChildcare programsCOVID-19Young childrenChildcare settingsChildrenPhysical distancingAssociation
2021
Comparative Effectiveness of Echinocandins vs Triazoles or Amphotericin B Formulations as Initial Directed Therapy for Invasive Candidiasis in Children and Adolescents
Fisher B, Zaoutis T, Xiao R, Wattier R, Castagnola E, Pana Z, Fullenkamp A, Boge C, Ross R, Yildirim I, Palazzi D, Danziger-Isakov L, Vora S, Arrieta A, Yin D, Avilés-Robles M, Sharma T, Tribble A, Maron G, Berman D, Green M, Sung L, Romero J, Hauger S, Roilides E, Belani K, Nolt D, Soler-Palacin P, López-Medina E, Muller W, Halasa N, Dulek D, Bin Hussain I, Pong A, Hoffman J, Rajan S, Gonzalez B, Hanisch B, Aftandilian C, Carlesse F, Abzug M, Huppler A, Salvatore C, Ardura M, Chakrabarti A, Santolaya M, Localio A, Steinbach W. Comparative Effectiveness of Echinocandins vs Triazoles or Amphotericin B Formulations as Initial Directed Therapy for Invasive Candidiasis in Children and Adolescents. Journal Of The Pediatric Infectious Diseases Society 2021, 10: 994-1003. PMID: 34374424, DOI: 10.1093/jpids/piab024.Peer-Reviewed Original ResearchAmphotericin B formulationsInvasive candidiasisAmphotericin B groupRisk differenceExposure groupB formulationsMultinational observational cohort studyCommon invasive fungal diseaseCrude failure rateData review committeeObservational cohort studyB groupInvasive fungal diseaseMantel-Haenszel analysisCohort studyPrimary outcomePrimary exposureFailure rateComparative effectivenessCandidiasisTherapyEffectiveness dataEchinocandinsReview CommitteeChildren
2018
The relative invasive disease potential of Streptococcus pneumoniae among children after PCV introduction: A systematic review and meta-analysis
Balsells E, Dagan R, Yildirim I, Gounder PP, Steens A, Muñoz-Almagro C, Mameli C, Kandasamy R, Lavi N, Daprai L, van der Ende A, Trzciński K, Nzenze SA, Meiring S, Foster D, Bulkow LR, Rudolph K, Valero-Rello A, Ducker S, Vestrheim DF, von Gottberg A, Pelton SI, Zuccotti G, Pollard AJ, Sanders EAM, Campbell H, Madhi SA, Nair H, Kyaw MH. The relative invasive disease potential of Streptococcus pneumoniae among children after PCV introduction: A systematic review and meta-analysis. Journal Of Infection 2018, 77: 368-378. PMID: 29964140, DOI: 10.1016/j.jinf.2018.06.004.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseInvasive disease potentialPneumococcal conjugate vaccineNon-vaccine typesPCV introductionPneumococcal diseaseClinical syndromePneumococcal serotypesSurveillance of IPDDisease potentialSystematic reviewCurrent pneumococcal conjugate vaccinesYears of ageRandom-effects modelConjugate vaccineRoutine immunisationDisease presentationFuture vaccinesStreptococcus pneumoniaeSerotype 1SerotypesSyndromeCarriageChildrenVaccine
2015
Pneumococcal Disease in the Era of Pneumococcal Conjugate Vaccine
Yildirim I, Shea KM, Pelton SI. Pneumococcal Disease in the Era of Pneumococcal Conjugate Vaccine. Infectious Disease Clinics Of North America 2015, 29: 679-697. PMID: 26610421, PMCID: PMC4662776, DOI: 10.1016/j.idc.2015.07.009.Peer-Reviewed Original ResearchConceptsPneumococcal conjugate vaccinePneumococcal diseaseConjugate vaccineOtitis mediaUniversal immunizationAcute otitis mediaInvasive pneumococcal diseaseCase fatality rateVulnerable pediatric patientsSpectrum of serotypesCause pneumoniaPediatric patientsComorbid conditionsHealthy childrenFatality rateDiseaseHost susceptibilityImmunizationVaccineHigh rateChildrenEmpyemaMastoiditisPneumoniaPatients
2009
Multicenter Prospective Study on the Burden of Rotavirus Gastroenteritis in Turkey, 2005–2006: A Hospital-Based Study
Ceyhan M, Alhan E, Salman N, Kurugol Z, Yildirim I, Celik U, Keser M, Koturoglu G, Tezer H, Bulbul EK, Karabocuoglu M, Halicioglu O, Anis S, Pawinski R. Multicenter Prospective Study on the Burden of Rotavirus Gastroenteritis in Turkey, 2005–2006: A Hospital-Based Study. The Journal Of Infectious Diseases 2009, 200: s234-s238. PMID: 19817603, DOI: 10.1086/605056.Peer-Reviewed Original ResearchConceptsRotavirus gastroenteritisWorld Health Organization's generic protocolRotavirus-positive childrenPrevalence of rotavirusMulticenter prospective studyRotavirus vaccineProspective surveillanceProspective studyDisease burdenMortality rateGastroenteritisPrevalent strainsRotavirusIndividual centersChildrenBurdenMain causeHospitalizationHospitalInfantsVaccineYearsPrevalence
2008
Cytomegalovirus hepatitis and ganciclovir treatment in immunocompetent children.
Tezer H, Seçmeer G, Kara A, Ceyhan M, Cengiz AB, Devrim I, Us D, Yüce A, Gürakan F, Yildirim I, Ozen H, Saltik-Temizel IN. Cytomegalovirus hepatitis and ganciclovir treatment in immunocompetent children. The Turkish Journal Of Pediatrics 2008, 50: 228-34. PMID: 18773667.Peer-Reviewed Original ResearchConceptsBiliary atresiaGanciclovir treatmentCauses of hepatitisCongenital CMV infectionExtrahepatic biliary atresiaSigns of infectionCMV hepatitisCholestatic hepatitisCMV infectionCytomegalovirus infectionImmunocompetent childrenStudy groupHepatitisPatientsGroup IIDemographic featuresGroup IInborn errorsInfectionAtresiaChildrenTreatmentGroupGenetic diseasesCMVComparing body temperature measurements by mothers and physicians using mercury-in-glass, digital mercury and infrared tympanic membrane thermometers in healthy newborn babies.
Cultu O, Yildirim I, Ceyhan M, Korkmaz A, Yurdakök M, Karaağaoğlu E, Seçmeer G. Comparing body temperature measurements by mothers and physicians using mercury-in-glass, digital mercury and infrared tympanic membrane thermometers in healthy newborn babies. The Turkish Journal Of Pediatrics 2008, 50: 354-8. PMID: 19014049.Peer-Reviewed Original ResearchConceptsNewborn babiesTympanic membrane thermometerEducational levelHealthy newborn babiesHealth care workersBody temperatureBody temperature changesHealthy newbornsProspective studyCare workersMedical carePediatriciansPrevious childIntraclass coefficientAbsolute differencePhysiciansTympanic thermometer measurementsMothersTympanic thermometerBody temperature measurementPresence of childrenBabiesDegrees CChildrenThermometer readings