The COMT Val/Met polymorphism is associated with reading‐related skills and consistent patterns of functional neural activation
Landi N, Frost SJ, Mencl WE, Preston JL, Jacobsen LK, Lee M, Yrigollen C, Pugh KR, Grigorenko EL. The COMT Val/Met polymorphism is associated with reading‐related skills and consistent patterns of functional neural activation. Developmental Science 2012, 16: 13-23. PMID: 23278923, PMCID: PMC3655431, DOI: 10.1111/j.1467-7687.2012.01180.x.Peer-Reviewed Original ResearchMeSH KeywordsCatechol O-MethyltransferaseChildCognitionFrontal LobeGenotypeHumansMagnetic Resonance ImagingPolymerase Chain ReactionPolymorphism, GeneticReadingVerbal BehaviorConceptsFunctional neural activationCOMT Val/Met polymorphismVal/Met polymorphismNeural activationReading-related skillsHigher-order cognitionMet polymorphismGood readersReading measuresReading skillsAdequate intelligenceCognitionSkillsCOMT geneBroad effectsIndividualsConsistent patternIntelligenceReadingChildrenAdultsDisabilityMeasuresRs4680Substantial portion