2023
Investigating the Face Inversion Effect in Autism Across Behavioral and Neural Measures of Face Processing
Griffin J, Azu M, Cramer-Benjamin S, Franke C, Herman N, Iqbal R, Keifer C, Rosenthal L, McPartland J. Investigating the Face Inversion Effect in Autism Across Behavioral and Neural Measures of Face Processing. JAMA Psychiatry 2023, 80: 1026-1036. PMID: 37405787, PMCID: PMC10323765, DOI: 10.1001/jamapsychiatry.2023.2105.Peer-Reviewed Original ResearchFace processing systemFace inversion effectAutism spectrum disorderInversion effectFace processingNeurotypical sampleAutistic individualsEffect sizeHuman social cognitionPerformance differencesFace recognition taskPerformance-based measuresSocial cognitionNeural measuresNeurotypical individualsPsychological constructsNeural responsesSpectrum disorderElectrophysiological measuresRecognition taskBrain functioningBehavioral paradigmsRecognition demandsIdentity recognitionNeural systems
2022
Linear discriminant analysis of phenotypic data for classifying autism spectrum disorder by diagnosis and sex
Jacokes Z, Jack A, Sullivan C, Aylward E, Bookheimer S, Dapretto M, Bernier R, Geschwind D, Sukhodolsky D, McPartland J, Webb S, Torgerson C, Eilbott J, Kenworthy L, Pelphrey K, Van Horn J, Consortium T, Ankenman K, Corrigan S, Depedro-Mercier D, Gaab N, Guilford D, Gupta A, Jeste S, Keifer C, Kresse A, Libsack E, Lowe J, MacDonnell E, McDonald N, Naples A, Nelson C, Neuhaus E, Ventola P, Welker O, Wolf J. Linear discriminant analysis of phenotypic data for classifying autism spectrum disorder by diagnosis and sex. Frontiers In Neuroscience 2022, 16: 1040085. PMID: 36466170, PMCID: PMC9709432, DOI: 10.3389/fnins.2022.1040085.Peer-Reviewed Original ResearchAutism spectrum disorderDiagnosis of ASDFemale protective effectSpectrum disorderParent-report measures
2020
Evidence of an Own-Age Bias in Facial Emotion Recognition for Adolescents With and Without Autism Spectrum Disorder
Hauschild KM, Felsman P, Keifer CM, Lerner MD. Evidence of an Own-Age Bias in Facial Emotion Recognition for Adolescents With and Without Autism Spectrum Disorder. Frontiers In Psychiatry 2020, 11: 428. PMID: 32581859, PMCID: PMC7286307, DOI: 10.3389/fpsyt.2020.00428.Peer-Reviewed Original ResearchOwn-age biasAutism spectrum disorderASD statusPerceptual expertiseFER taskSpectrum disorderFace recognition memoryFace processing deficitsFacial emotion recognitionAbility of adolescentsRecognition memoryAdult facesEmotion recognitionASD severityFER accuracyProcessing advantageConsistent deficitsNormative levelsAdolescentsOwn agePoor performanceTaskDeficitsFaceFER performancePrediction of social behavior in autism spectrum disorders: Explicit versus implicit social cognition
Keifer CM, Mikami AY, Morris JP, Libsack EJ, Lerner MD. Prediction of social behavior in autism spectrum disorders: Explicit versus implicit social cognition. Autism 2020, 24: 1758-1772. PMID: 32484000, PMCID: PMC7541482, DOI: 10.1177/1362361320922058.Peer-Reviewed Original ResearchConceptsImplicit social cognitionAutism spectrum disorderExplicit social cognitionSocial cognitionCompetent social behaviorSpectrum disorderSocial behaviorSocial deficitsSocial informationSocial cognition abilitiesDevelopment of interventionsCognition abilitiesSocial communicationBrain measuresSocial situationsCognitionSocial normsDeficitsHallmark featureResult of problemsDisordersDifficultiesMeasuresBehaviorYouth
2019
Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder
Keifer CM, Hauschild KM, Nelson BD, Hajcak G, Lerner MD. Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder. Journal Of Autism And Developmental Disorders 2019, 49: 5009-5022. PMID: 31486998, DOI: 10.1007/s10803-019-04207-6.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderLow-intensity faceASD symptomatologyEmotional intensitySpectrum disorderFacial emotion recognition taskEarly event-related potential (ERP) responsesEvent-related potential responsesLate positive potentialSocial-emotional processingEmotion recognition taskSocial-emotional stimuliHigh intensity facesEmotional facesElaborative processingEmotional stimuliEmotional processingRecognition taskPositive potentialsP300StimuliSymptomatologyFaceProcessingAdultsDiscrete electrocortical predictors of anxiety and anxiety-related treatment response in youth with autism spectrum disorder
Kang E, Clarkson T, Keifer CM, Rosen TE, Lerner MD. Discrete electrocortical predictors of anxiety and anxiety-related treatment response in youth with autism spectrum disorder. Biological Psychology 2019, 146: 107710. PMID: 31158425, DOI: 10.1016/j.biopsycho.2019.05.010.Peer-Reviewed Original ResearchConceptsSocial skills interventionsAutism spectrum disorderError-related negativitySelf-reported social anxiety symptomsSocial anxiety symptomsAnxiety symptomsSpectrum disorderNegative error-related negativityRelative right frontal activitySelf-reported anxiety symptomsRight frontal activityUnique neural mechanismsWithdrawal motivationThreat sensitivitySkills interventionNeural mechanismsFrontal activitySubjective reportsAnxiety domainsAnxiety phenotypeYouthAnxietyTreatment responseElectroencephalogramDisorders
2018
Autism Spectrum Disorder
Lerner M, Rosen T, Kang E, Keifer C, Gerber A. Autism Spectrum Disorder. 2018, 223-234. DOI: 10.1093/oxfordhb/9780190634841.013.15.Peer-Reviewed Original ResearchAbstract Autism spectrum disorderAutism spectrum disorderComplex clinical presentationSymptom reductionRepetitive behaviorsProportion of youthSpectrum disorderPsychosocial interventionsNeurodevelopmental conditionsSocial communicationCase examplePercentage of youthIntervention practicesReview keyYouthClinical practiceInterventionDeficitsAdolescentsDisordersSymptomsExternalitiesAssessment
2017
Atypicality of the N170 Event-Related Potential in Autism Spectrum Disorder: A Meta-analysis
Kang E, Keifer CM, Levy EJ, Foss-Feig JH, McPartland JC, Lerner MD. Atypicality of the N170 Event-Related Potential in Autism Spectrum Disorder: A Meta-analysis. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2017, 3: 657-666. PMID: 30092916, PMCID: PMC6089230, DOI: 10.1016/j.bpsc.2017.11.003.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderEvent-related potentialsN170 responseN170 latencySpectrum disorderN170 event-related potentialPromising neural markerImpaired face processingHigher cognitive abilitiesFace processingFunction of hemisphereASD participantsN170 amplitudesN170 differencesTD individualsCognitive mechanismsTD participantsASD differCognitive abilitiesPotential moderatorsDevelopmental experiencesHemispheric differencesNeural markersAdult samplesClinical populations