2013
Neural processing of intentional biological motion in unaffected siblings of children with autism spectrum disorder: An fMRI study
Ahmed A, Vander Wyk B. Neural processing of intentional biological motion in unaffected siblings of children with autism spectrum disorder: An fMRI study. Brain And Cognition 2013, 83: 297-306. PMID: 24128657, PMCID: PMC3869032, DOI: 10.1016/j.bandc.2013.09.007.Peer-Reviewed Original ResearchConceptsPosterior superior temporal sulcusSiblings of childrenAutism spectrum disorderSpectrum disorderBiological motionSocial cognitive abilitiesDorsolateral prefrontal cortexControl childrenSuperior temporal sulcusFunctional magnetic resonanceSample of childrenCongruent trialsPrefrontal cortexIncongruent actionsFMRI studyEmotional cuesTemporal sulcusMorphological deficitsAction perceptionCognitive abilitiesBrain regionsNeural processesAutism samplesCompensatory reorganizationAutism
2010
Neural signatures of autism
Kaiser MD, Hudac CM, Shultz S, Lee SM, Cheung C, Berken AM, Deen B, Pitskel NB, Sugrue DR, Voos AC, Saulnier CA, Ventola P, Wolf JM, Klin A, Vander Wyk B, Pelphrey KA. Neural signatures of autism. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 21223-21228. PMID: 21078973, PMCID: PMC3000300, DOI: 10.1073/pnas.1010412107.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderNeural signaturesBiological motionBrain responsesUnaffected siblingsDistinct brain responsesFunctional magnetic resonanceAreas of dysfunctionNature of disruptionTD childrenSpectrum disorderDisorder heterogeneityNeural systemsBrain circuitryBehavioral profileCompensatory activitySystem-level mechanismsTrait activityAutismChildrenIncreased genetic riskGenetic riskState activityNeuroendophenotypesDisorders