2024
Post-traumatic stress disorder symptoms following exposure to acute psychological trauma in children aged 8–16 years in South Africa: protocol for the Sinethemba longitudinal study
Sharp T, Chideya Y, Giuliani A, Hunt X, Tomlinson M, Seedat S, Creswell C, Fearon P, Hamilton-Giachritsis C, Hiller R, Meiser-Stedman R, Du Toit S, Stewart J, Halligan S. Post-traumatic stress disorder symptoms following exposure to acute psychological trauma in children aged 8–16 years in South Africa: protocol for the Sinethemba longitudinal study. BMJ Open 2024, 14: e085129. PMID: 38991675, DOI: 10.1136/bmjopen-2024-085129.Peer-Reviewed Original ResearchConceptsMental health outcomesPost-traumatic stress disorderChildren aged 8Caregiver supportHealth outcomesAssociation of psychosocial factorsAdverse mental health outcomesAged 8Traumatic eventsChildren’s post-traumatic stress disorderDepartment of HealthMiddle-income countriesTrauma-related mental healthPsychological risk factorsHigh-income countriesStress disorder symptomsFollow-up assessmentPost-traumatic stress disorder symptomsCape TownMotor vehicle accidentsHealthcare clinicsPsychosocial factorsMental healthPsychological recoveryEthical approvalImplementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya—individually randomised superiority trial
Fonagy P, Chammay R, Ngunu C, Kumar M, Verdeli L, Allison E, Anani G, Fearon P, Fouad F, Hoare Z, Koyio L, Moore H, Nyandigisi A, Pilling S, Sender H, Skordis J, Evans R, Jaoude G, Madeghe B, Maradian S, O’Donnell C, Simes E, Truscott A, Wambua G, Yator O. Implementing and evaluating group interpersonal therapy for postnatal depression in Lebanon and Kenya—individually randomised superiority trial. Trials 2024, 25: 217. PMID: 38532432, PMCID: PMC10964704, DOI: 10.1186/s13063-024-08039-3.Peer-Reviewed Original ResearchConceptsPostnatal depressionInterpersonal psychotherapyChild developmental outcomesMulti-site randomised controlled trialWomen's mental health needsStandard careEfficacy of interpersonal psychotherapyMaternal postnatal depressionMental health needsMental health concernsMiddle-income countriesRandomised controlled trialsDevelopmental outcomesHigh-income countriesAntenatal servicesChildbearing womenMother-child bondingRandomised superiority trialChildren's developmental progressHealth needsOffspring of womenMaternal depressionCommunity settingsLMIC contextsInterpersonal therapy
2022
Patterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis
Hemady C, Speyer L, Murray A, Brown R, Meinck F, Fry D, Do H, Sikander S, Madrid B, Fernando A, Walker S, Dunne M, Foley S, Hughes C, Osafo J, Baban A, Taut D, Ward C, Van Thang V, Fearon P, Tomlinson M, Valdebenito S, Eisner M. Patterns of adverse childhood experiences and associations with prenatal substance use and poor infant outcomes in a multi-country cohort of mothers: a latent class analysis. BMC Pregnancy And Childbirth 2022, 22: 505. PMID: 35733125, PMCID: PMC9215006, DOI: 10.1186/s12884-022-04839-0.Peer-Reviewed Original ResearchConceptsPrenatal substance usePoor infant outcomesAdverse childhood experiencesInfant outcomesHousehold dysfunctionSubstance useLatent class analysisPrenatal drug useMother-infant dyadsLow-risk classMultilevel logistic regressionChildhood experiencesAntenatal supportHigh-risk classMiddle-income countriesStudy cohortLow birthweightPerinatal periodDrug useConclusionOur resultsChildhood adversityClass analysisLogistic regressionViolence exposureDysfunctionPerceived stress during the prenatal period: assessing measurement invariance of the Perceived Stress Scale (PSS-10) across cultures and birth parity
Katus L, Foley S, Murray A, Luong-Thanh B, Taut D, Baban A, Madrid B, Fernando A, Sikander S, Ward C, Osafo J, Marlow M, Du Toit S, Walker S, Van Vo T, Fearon P, Valdebenito S, Eisner M, Hughes C. Perceived stress during the prenatal period: assessing measurement invariance of the Perceived Stress Scale (PSS-10) across cultures and birth parity. Archives Of Women's Mental Health 2022, 25: 633-640. PMID: 35420323, PMCID: PMC9072510, DOI: 10.1007/s00737-022-01229-5.Peer-Reviewed Original Research
2021
The impact of maternal adverse childhood experiences and prenatal depressive symptoms on foetal attachment: Preliminary evidence from expectant mothers across eight middle-income countries
Brown R, Eisner M, Walker S, Tomlinson M, Fearon P, Dunne M, Valdebenito S, Hughes C, Ward C, Sikander S, Osafo J, Madrid B, Baban A, Van Thang V, Fernando A, Murray A. The impact of maternal adverse childhood experiences and prenatal depressive symptoms on foetal attachment: Preliminary evidence from expectant mothers across eight middle-income countries. Journal Of Affective Disorders 2021, 295: 612-619. PMID: 34509077, DOI: 10.1016/j.jad.2021.08.066.Peer-Reviewed Original ResearchConceptsMaternal adverse childhood experiencesAdverse childhood experiencesPrenatal depressive symptomsMiddle-income countriesPrenatal depressionDepressive symptomsMaternal health careChildhood experiencesAntenatal careThird trimesterCohort evidenceACE exposureHigh-income countriesPostnatal periodExpectant mothersBaseline measurementsPostnatal attachmentSymptomsPath mediation analysisRelevant covariatesDepressionHealth careMothers' feelingsMothersPregnancyPrenatal attachment: using measurement invariance to test the validity of comparisons across eight culturally diverse countries
Foley S, Hughes C, Murray A, Baban A, Fernando A, Madrid B, Osafo J, Sikander S, Abbasi F, Walker S, Luong-Thanh B, Vo T, Tomlinson M, Fearon P, Ward C, Valdebenito S, Eisner M. Prenatal attachment: using measurement invariance to test the validity of comparisons across eight culturally diverse countries. Archives Of Women's Mental Health 2021, 24: 619-625. PMID: 33559754, PMCID: PMC8266779, DOI: 10.1007/s00737-021-01105-8.Peer-Reviewed Original ResearchConceptsMaternal-fetal attachmentMiddle-income countriesHigh-income countriesExpectant mothersProspective birth cohort studyBirth cohort studyFirst-time mothersPrenatal Attachment InventoryCohort studyThird trimesterPregnant womenMaternal healthFirst infantMaternal behaviorGroup comparisonsMean levelsMothersInfantsSingle latent factorFuture studiesPlace childrenChildrenChild outcomesSimilar informationPAI
2020
PTSD symptoms and cortisol stress reactivity in adolescence: Findings from a high adversity cohort in South Africa
Zimmerman A, Halligan S, Skeen S, Morgan B, Fraser A, Fearon P, Tomlinson M. PTSD symptoms and cortisol stress reactivity in adolescence: Findings from a high adversity cohort in South Africa. Psychoneuroendocrinology 2020, 121: 104846. PMID: 32919210, DOI: 10.1016/j.psyneuen.2020.104846.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderCortisol stress reactivityTrier Social Stress TestPTSD symptomsTrauma exposureStress reactivityHPA axis stress reactivitySmall inverse associationHPA stress reactivitySex-specific associationsTotal cortisol outputElevated PTSD symptomsImpoverished South African communityMiddle-income countriesAdrenal axisInverse associationSocial Stress TestMiddle-income country contextCortisol responsePsychosocial stressCortisol outputCortisol increaseSalivary cortisolStress disorderSouth African community