Yale Researchers Take Stem Cells One Step Closer to Replacing Parathyroid Gland Function
Yale investigators have developed a multistep process that models the biological instructions to create parathyroid gland cells from pluripotent stem cells, a significant milestone along the path toward helping people who lack the hormones released by parathyroid glands.
Knowing the Risks: The Genetics of Breast and Ovarian Cancer
Dr. Ryan Jensen’s work, spurred by a pair of WHRY grants, continues progress toward models uncovering how genetic mutations lead to cancer and helping guide patients and doctors toward decisions that can produce the best health outcomes.
Twenty years and counting for Women's Health Research at Yale
Women’s Health Research at Yale (WHRY), a self-supporting center within Yale School of Medicine, will celebrate its 20th anniversary in February. With data developed through $5 million in WHRY grants to date, Yale scientists have gone on to secure $95 million in external grants to further their research into women’s health.Source: Medicine@Yale
PFAS and Phenols Linked to Different Cancers in Women of Different Races
A new federally-funded study in the Journal of Exposure Science & Environmental Epidemiology has found that compounds called phenols, and the synthetic chemicals PFAS, were linked to different kinds of cancer in white women and women of color. PFAS were linked to ovarian and uterine cancers mainly in white women, and phenols were linked more to breast cancer in non-white women. Phenols and PFAS are found in hundreds of daily consumer products. The researchers stated that the racial differences are particularly impactful because of racial disparities in exposure to these chemicals. Nicole Deziel, member of the Yale Cancer Center and associate professor of epidemiology (environmental sciences) at Yale School of Public Health, who is not associated with the study, said the findings “provided a lot of new information suggesting that exposure to PFAS could be associated with a variety of hormonally related cancers, particularly in women.”Source: CT Public Radio
Metabolomic Research Links Diet to Paraben Food Preservatives in Urine, Findings Important for Women Trying to Conceive
Yale researchers identify diet-related metabolites associated with paraben concentrations in the urine of pregnant women. Parabens can disrupt endocrine activity in the body and they have been associated with changes in fertility in women.