Publications

2025

• Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromataseAladelokun O, Benitez K, Wang Y, Jain A, Berardi D, Maroun G, Shen X, Roper J, Gibson J, Sumigray K, Khan S, Johnson C. Sex-specific effects of exogenous asparagine on colorectal tumor growth, 17β-estradiol levels, and aromatase. Pharmacological Research 2025, 107736. PMID: 40228761, DOI: 10.1016/j.phrs.2025.107736.
• Natural killer cells’ functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromesRodriguez-Sevilla J, Ganan-Gomez I, Kumar B, Thongon N, Ma F, Chien K, Kim Y, Yang H, Loghavi S, Tan R, Adema V, Li Z, Tanaka T, Uryu H, Kanagal-Shamanna R, Al-Atrash G, Bejar R, Banerjee P, Lynn Cha S, Montalban-Bravo G, Dougherty M, Fernandez Laurita M, Wheeler N, Jia B, Papapetrou E, Izzo F, Dueñas D, McAllen S, Gu Y, Todisco G, Ficara F, Della Porta M, Jain A, Takahashi K, Clise-Dwyer K, Halene S, Bertilaccio M, Garcia-Manero G, Daher M, Colla S. Natural killer cells’ functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes. Nature Communications 2025, 16: 3450. PMID: 40216768, DOI: 10.1038/s41467-025-58662-0.
• Hepatoblastoma: Comprehensive Review With Recent Updates.Jiao J, Saxena R, Morotti R. Hepatoblastoma: Comprehensive Review With Recent Updates. Adv Anat Pathol 2025 PMID: 40178831, DOI: 10.1097/PAP.0000000000000495.
• An in vivo screen identifies NAT10 as a master regulator of brain metastasis.Chen JF, Xu P, Cai WL, Chen H, Wingrove E, Shi X, Li W, Biancon G, Zhang M, Balabaki A, Krop ED, Asare E, Zhang Y, Yin M, Tebaldi T, Meier JL, Westbrook TF, Halene S, Liu Y, Shen H, Nguyen DX, Yan Q. An in vivo screen identifies NAT10 as a master regulator of brain metastasis. Sci Adv 2025, 11: eads6021. PMID: 40138393, DOI: 10.1126/sciadv.ads6021.
• Reducing clinical trial eligibility barriers for patients with MDS: an icMDS position statementBorate U, Pugh K, Waller A, Welkie R, Huang Y, Bewersdorf J, Stahl M, DeZern A, Platzbecker U, Sekeres M, Wei A, Buckstein R, Roboz G, Savona M, Loghavi S, Hasserjian R, Fenaux P, Sallman D, Hourigan C, Della Porta M, Nimer S, Little R, Santini V, Efficace F, Taylor J, Garcia-Manero G, Odenike O, Kim T, Halene S, Komrokji R, Griffiths E, Greenberg P, Xu M, Xie Z, Bejar R, Sanz G, Patnaik M, Figueroa M, Carraway H, Abdel-Wahab O, Starczynowski D, Padron E, Boultwood J, Gore S, Daver N, Churpek J, Majeti R, Bennett J, List A, Brunner A, Zeidan A. Reducing clinical trial eligibility barriers for patients with MDS: an icMDS position statement. Blood 2025, 145: 1369-1381. PMID: 40146152, DOI: 10.1182/blood.2023023717.
• In the time of COVID-19: challenges, successes and lessons learned from studies in cancer patientsMack P, Crawford J, Chang A, Yin A, Klein S, Shea P, Hirsch F, Zidar D, Simon V, Gleason C, McBride R, Cordon-Cardo C, VanOudenhove J, Halene S, Lee F, Mantis N, Kushi L, Weiskopf D, Merchant A, Reckamp K, Skarbinski J, Figueiredo J. In the time of COVID-19: challenges, successes and lessons learned from studies in cancer patients. Journal Of The National Cancer Institute 2025, djaf073. PMID: 40127178, DOI: 10.1093/jnci/djaf073.
• Spatial transcriptomics reveals differential inflammatory pathways in discoid lupus erythematosus and lichen planusKidacki M, Cho C, Lopez-Giraldez F, Breidbart R, Jaiswal A, Lee M, Chowdhury S, Damsky W, Chen L, Vesely M. Spatial transcriptomics reveals differential inflammatory pathways in discoid lupus erythematosus and lichen planus. Journal Of Investigative Dermatology 2025 PMID: 40113031, DOI: 10.1016/j.jid.2025.02.148.
• IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer.Ranjan K, Rajendran BK, Deen IU, Costantini A, de Rodas ML, Desai SS, Scallo F, Gianino N, Ferrone S, Schalper KA. IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer. Mol Cancer 2025, 24: 80. PMID: 40091029, DOI: 10.1186/s12943-025-02276-z.
• The neuropathologic basis for translational biomarker development in the macaque model of late-onset Alzheimer's disease.Zeiss C, Huttner A, Nairn A, Arnsten A, Datta D, Strittmatter S, Wyk B, Duque A. The neuropathologic basis for translational biomarker development in the macaque model of late-onset Alzheimer's disease. Journal Of Alzheimer's Disease 2025, 13872877251323787. PMID: 40095666, DOI: 10.1177/13872877251323787.
• Correction: EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repairKoyen A, Madden M, Park D, Minten E, Kapoor-Vazirani P, Werner E, Pfister N, Haji-Seyed-Javadi R, Zhang H, Xu J, Deng N, Duong D, Pecen T, Frazier Z, Nagel Z, Lazaro J, Mouw K, Seyfried N, Moreno C, Owonikoko T, Deng X, Yu D. Correction: EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair. Oncogene 2025, 44: 928-930. PMID: 40097809, DOI: 10.1038/s41388-025-03345-9.
• BCL2 inhibition for multiple myeloma and AL amyloidosisCani L, Gupta V, Kaufman J. BCL2 inhibition for multiple myeloma and AL amyloidosis. British Journal Of Haematology 2025 PMID: 40090369, DOI: 10.1111/bjh.20046.
• Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer’s diseaseCai Y, Kanyo J, Wilson R, Bathla S, Cardozo P, Tong L, Qin S, Fuentes L, Pinheiro-de-Sousa I, Huynh T, Sun L, Mansuri M, Tian Z, Gan H, Braker A, Trinh H, Huttner A, Lam T, Petsalaki E, Brennand K, Nairn A, Grutzendler J. Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer’s disease. Nature Aging 2025, 5: 504-527. PMID: 40065072, PMCID: PMC11922768, DOI: 10.1038/s43587-025-00823-3.
• Machine learning-based spatial characterization of tumor-immune microenvironment in the EORTC 10994/BIG 1-00 early breast cancer trialZerdes I, Matikas A, Mezheyeuski A, Manikis G, Acs B, Johansson H, Boyaci C, Boman C, Poncet C, Ignatiadis M, Bai Y, Rimm D, Cameron D, Bonnefoi H, Bergh J, MacGrogan G, Foukakis T. Machine learning-based spatial characterization of tumor-immune microenvironment in the EORTC 10994/BIG 1-00 early breast cancer trial. Npj Breast Cancer 2025, 11: 23. PMID: 40055382, DOI: 10.1038/s41523-025-00730-1.
• An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesisEl Bounkari O, Zan C, Yang B, Ebert S, Wagner J, Bugar E, Kramer N, Bourilhon P, Kontos C, Zarwel M, Sinitski D, Milic J, Jansen Y, Kempf W, Sachs N, Maegdefessel L, Ji H, Gokce O, Riols F, Haid M, Gerra S, Hoffmann A, Brandhofer M, Avdic M, Bucala R, Megens R, Willemsen N, Messerer D, Schulz C, Bartelt A, Harm T, Rath D, Döring Y, Gawaz M, Weber C, Kapurniotu A, Bernhagen J. An atypical atherogenic chemokine that promotes advanced atherosclerosis and hepatic lipogenesis. Nature Communications 2025, 16: 2297. PMID: 40055309, DOI: 10.1038/s41467-025-57540-z.
• Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases.Weiss S, Djureinovic D, Wei W, Tran T, Austin M, Markowitz J, Eroglu Z, Khushalani N, Hegde U, Cohen J, Sznol M, Anderson G, Johnson B, Piteo C, Mahajan A, Adeniran A, Jilaveanu L, Goldberg S, Chiang V, Forsyth P, Kluger H. Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases. Journal Of Clinical Oncology 2025, jco2402219. PMID: 40048689, DOI: 10.1200/jco-24-02219.
• Quantitative Protein Expression of Antibody-Drug Conjugate Targets in EGFR Mutated and Wild-Type Non-Small Cell Lung Cancer.Trontzas I, He M, Wurtz A, Robbins C, Robinson N, Bates K, Liu M, Aung T, Scott L, Chan N, Burela S, Schillo J, Liebler D, Hill S, Morrison R, Vathiotis I, Syrigos K, Goldberg S, Politi K, Rimm D. Quantitative Protein Expression of Antibody-Drug Conjugate Targets in EGFR Mutated and Wild-Type Non-Small Cell Lung Cancer. Clinical Cancer Research 2025 PMID: 40047548, DOI: 10.1158/1078-0432.ccr-24-3347.
• Associations between Blood DNA Methylation and Histopathological Features in Lupus Nephritis.Demkowicz P, Kavaliauskaite I, Faulkner S, Kent C, Shaw M, Kumar D, Ix J, Wilson F, Moledina D, Bakhoum M, Bakhoum C. Associations between Blood DNA Methylation and Histopathological Features in Lupus Nephritis. Kidney360 2025 PMID: 40048255, DOI: 10.34067/kid.0000000758.
• A single-cell atlas of circulating immune cells over the first 2 months of age in extremely premature infantsOlaloye O, Gu W, Gehlhaar A, Sabuwala B, Eke C, Li Y, Kehoe T, Farmer R, Gabernet G, Lucas C, Tsang J, Lakhani S, Taylor S, Tseng G, Kleinstein S, Konnikova L. A single-cell atlas of circulating immune cells over the first 2 months of age in extremely premature infants. Science Translational Medicine 2025, 17: eadr0942. PMID: 40043141, DOI: 10.1126/scitranslmed.adr0942.
• Integrating epidemiology and genomics data to estimate the prevalence of acquired cysteine drug targets in the U.S. cancer patient populationArun A, Liarakos D, Mendiratta G, Kim J, Goshua G, Olson P, Stites E. Integrating epidemiology and genomics data to estimate the prevalence of acquired cysteine drug targets in the U.S. cancer patient population. The Pharmacogenomics Journal 2025, 25: 5. PMID: 40044654, DOI: 10.1038/s41397-025-00364-3.
• Hypercholesterolemia-induced LXR signaling in smooth muscle cells contributes to vascular lesion remodeling and visceral functionZhang H, de Urturi D, Fernández-Tussy P, Huang Y, Jovin D, Zhang X, Huang S, Lek M, da Silva Catarino J, Sternak M, Citrin K, Swirski F, Gustafsson J, Greif D, Esplugues E, Biwer L, Suárez Y, Fernández-Hernando C. Hypercholesterolemia-induced LXR signaling in smooth muscle cells contributes to vascular lesion remodeling and visceral function. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2417512122. PMID: 40035761, PMCID: PMC11912459, DOI: 10.1073/pnas.2417512122.
• Morphological alterations of the thymus gland in individuals with schizophreniaZhao Q, Wei X, Yu W, Li X, Gao Z, Liu S, Liu Z, Wang K, Bishop J, Hu H, Luo C, Xiao Y, Hu N, Tao B, Zhu F, Gong Q, Lui S. Morphological alterations of the thymus gland in individuals with schizophrenia. Molecular Psychiatry 2025, 1-11. PMID: 40038543, DOI: 10.1038/s41380-025-02946-w.
• Drugging Disordered Proteins by Conformational Selection to Inform Therapeutic InterventionBogin B, Levine Z. Drugging Disordered Proteins by Conformational Selection to Inform Therapeutic Intervention. Journal Of Chemical Theory And Computation 2025, 21: 3204-3215. PMID: 40029731, DOI: 10.1021/acs.jctc.4c01160.
• Advancements in minimally invasive interventional oncology procedures for painful sacral metastases under imaging guidanceJiang W, Gan D, Johnson M, Latich I, Lee F. Advancements in minimally invasive interventional oncology procedures for painful sacral metastases under imaging guidance. EngMedicine 2025, 2: 100051. DOI: 10.1016/j.engmed.2024.100051.
• 110 Characterization of Frequency and Spectrum of PIK3CA Somatic Mutations in Advanced Breast CancerAmraei R, Kahn A, Walther Z, Finberg K, Gibson J, Kahila M. 110 Characterization of Frequency and Spectrum of PIK3CA Somatic Mutations in Advanced Breast Cancer. Laboratory Investigation 2025, 105: 102334. DOI: 10.1016/j.labinv.2024.102334.
• 1035 Pathological and Molecular Signatures of De-differentiated Endometrial Carcinomas- An Institutional Study of 52 CasesArbelaez C, Babb P, Sun T, Buza N, Hui P. 1035 Pathological and Molecular Signatures of De-differentiated Endometrial Carcinomas- An Institutional Study of 52 Cases. Laboratory Investigation 2025, 105: 103269. DOI: 10.1016/j.labinv.2024.103269.
• 1044 Discordant HER2 Scores in Endometrial Cancer Using Endometrial versus Gastric Criteria: Implications for treatment eligibilityMoscona A, Babb P, Rottmann D, Sun T, Hui P, Buza N. 1044 Discordant HER2 Scores in Endometrial Cancer Using Endometrial versus Gastric Criteria: Implications for treatment eligibility. Laboratory Investigation 2025, 105: 103278. DOI: 10.1016/j.labinv.2024.103278.
• Real-world outcomes with T-VEC in patients with anti-PD-1 resistant in-transit disease from melanoma and Merkel cell carcinomaSu D, McNamara M, Kaszycki M, Frey A, Ishizuka J, Costa P, Tran T, Kluger H, Clune J, Weiss S, Olino K. Real-world outcomes with T-VEC in patients with anti-PD-1 resistant in-transit disease from melanoma and Merkel cell carcinoma. Surgical Oncology Insight 2025, 2: 100120. DOI: 10.1016/j.soi.2024.100120.
• Response and Outcomes of Patients with IDH1/2 Mutated Accelerated/Blast-Phase Myeloproliferative NeoplasmsGoldberg L, Yoon J, Johnston H, Davidson M, Siddon A, Shallis R, Chen E, Burkart M, Oh T, Iyer S, Madarang E, Muthiah C, Kassner J, Rampal R, Murthy S, Bradley T, Abaza Y, Garcia J, Gupta V, Pettit K, Odenike O, Cursio J, Patel A. Response and Outcomes of Patients with IDH1/2 Mutated Accelerated/Blast-Phase Myeloproliferative Neoplasms. Blood Neoplasia 2025, 100089. DOI: 10.1016/j.bneo.2025.100089.
• 340 Cytomorphologic Challenges in Cervical Pap Tests of Transgender Men on Androgen Therapy: A Cyto-Histological Correlation StudyHaque M, Amraei R, Iyer K, Krishnamurti U, Adeniran A, Sun T. 340 Cytomorphologic Challenges in Cervical Pap Tests of Transgender Men on Androgen Therapy: A Cyto-Histological Correlation Study. Laboratory Investigation 2025, 105: 102567. DOI: 10.1016/j.labinv.2024.102567.
• 711 Gastric Adenocarcinoma in Autoimmune Atrophic Gastritis: Clinicopathologic Study of 18 Cases with Focus on Pyloric Gland Type AdenocarcinomaWang X, Jiao J, Huh W, Zhang X. 711 Gastric Adenocarcinoma in Autoimmune Atrophic Gastritis: Clinicopathologic Study of 18 Cases with Focus on Pyloric Gland Type Adenocarcinoma. Laboratory Investigation 2025, 105: 102942. DOI: 10.1016/j.labinv.2024.102942.
• 604 Whole Exome Sequencing Reveals Genetic Alterations Involving MEN1 as a Potential Mechanism of Wnt Signaling Activation in Gastric Adenocarcinoma of the Fundic Gland TypeHuh W, Bearse M, Finberg K, Jain D. 604 Whole Exome Sequencing Reveals Genetic Alterations Involving MEN1 as a Potential Mechanism of Wnt Signaling Activation in Gastric Adenocarcinoma of the Fundic Gland Type. Laboratory Investigation 2025, 105: 102835. DOI: 10.1016/j.labinv.2024.102835.
• 315 Clinicopathologic Characteristics of Thyroid Nodules with THADA-IGF2BP3 Fusion Identified on Fine Needle AspirationBernhisel A, Sun T, Prasad M, Ladenheim A, Cai G, Adeniran A. 315 Clinicopathologic Characteristics of Thyroid Nodules with THADA-IGF2BP3 Fusion Identified on Fine Needle Aspiration. Laboratory Investigation 2025, 105: 102542. DOI: 10.1016/j.labinv.2024.102542.
• 411 Correlation of ACR-TI-RADS, Cytology, Histology, and Molecular studiesYu S, Wang M, Langdon J, Sinard J, Cai G, Prasad M, Adeniran A. 411 Correlation of ACR-TI-RADS, Cytology, Histology, and Molecular studies. Laboratory Investigation 2025, 105: 102638. DOI: 10.1016/j.labinv.2024.102638.
• 542 Clinicopathologic Features of Thyroid Nodules with BRAF non-V600E MutationsVerma A, Cedeño E, Abi-Raad R, Ladenheim A, Prasad M. 542 Clinicopathologic Features of Thyroid Nodules with BRAF non-V600E Mutations. Laboratory Investigation 2025, 105: 102772. DOI: 10.1016/j.labinv.2024.102772.
• 401 Prognostic Value of Pelvic Washing Cytology in Early-Stage Endometrial Cancer: A 10-Year Single-Institute Cohort StudyWang M, Abi-Raad R, Krishnamurti U, Cai G, Adeniran A, Sun T. 401 Prognostic Value of Pelvic Washing Cytology in Early-Stage Endometrial Cancer: A 10-Year Single-Institute Cohort Study. Laboratory Investigation 2025, 105: 102628. DOI: 10.1016/j.labinv.2024.102628.
• 351 Follicular Neoplasms: Cytomorphological Subclassification, Molecular Alterations and Risk of MalignancyKaur H, Gereg C, Abi-Raad R, Adeniran A, Cai G. 351 Follicular Neoplasms: Cytomorphological Subclassification, Molecular Alterations and Risk of Malignancy. Laboratory Investigation 2025, 105: 102578. DOI: 10.1016/j.labinv.2024.102578.
• 334 Utility of SATB2 Immunocytochemistry in the Diagnostic Workup of Cytological Specimens from Patients with Suspected OsteosarcomaGereg C, Cai G. 334 Utility of SATB2 Immunocytochemistry in the Diagnostic Workup of Cytological Specimens from Patients with Suspected Osteosarcoma. Laboratory Investigation 2025, 105: 102561. DOI: 10.1016/j.labinv.2024.102561.
• 341 Comparative Assessment of Claudin-4, MOC-31, and BerEP4 Immunomarkers in Diagnostic Workup of Metastatic Carcinoma in Serous Fluid SpecimensHaque M, Kaur H, Wang M, Cai G. 341 Comparative Assessment of Claudin-4, MOC-31, and BerEP4 Immunomarkers in Diagnostic Workup of Metastatic Carcinoma in Serous Fluid Specimens. Laboratory Investigation 2025, 105: 102568. DOI: 10.1016/j.labinv.2024.102568.
• 116 Pathological and Molecular Characterization of Estrogen Receptor-Positive/HER2-Negative de novo Metastatic Breast CancerBabb P, Theriot J, Liang Y, Cartagena L, Buza N, Krishnamurti U, Zhan H. 116 Pathological and Molecular Characterization of Estrogen Receptor-Positive/HER2-Negative de novo Metastatic Breast Cancer. Laboratory Investigation 2025, 105: 102340. DOI: 10.1016/j.labinv.2024.102340.
• 213 Focal Atypical Ductal Hyperplasia (ADH) Upgrade Rate with Radiological Correlation: A Single Institution StudyPodany P, Kahila M, Proussaloglou E, Lewin J, Andrejeva L, Krishnamurti U. 213 Focal Atypical Ductal Hyperplasia (ADH) Upgrade Rate with Radiological Correlation: A Single Institution Study. Laboratory Investigation 2025, 105: 102437. DOI: 10.1016/j.labinv.2024.102437.
• 270 Pathological Response to Herceptin-containing Neoadjuvant Therapy in HER2 IHC2+/ISH+ and IHC3+ Early-Stage Breast CancersZhan H, Chan N, Rimm D. 270 Pathological Response to Herceptin-containing Neoadjuvant Therapy in HER2 IHC2+/ISH+ and IHC3+ Early-Stage Breast Cancers. Laboratory Investigation 2025, 105: 102494. DOI: 10.1016/j.labinv.2024.102494.
• 127 Analytical Validation and Prospective Study of a High-Sensitivity HER2 (HS-HER2) Quantitative Immunofluorescence Assay for Enhanced Stratification of HER2-Low Breast Cancer PatientsChan N, Gaule P, Benanto J, Robbins C, Scott L, Hill S, Morrison R, Liebler D, Fulton R, Rimm D. 127 Analytical Validation and Prospective Study of a High-Sensitivity HER2 (HS-HER2) Quantitative Immunofluorescence Assay for Enhanced Stratification of HER2-Low Breast Cancer Patients. Laboratory Investigation 2025, 105: 102351. DOI: 10.1016/j.labinv.2024.102351.
• 119 Reading vs Measuring: Comparison of Pathologist-Based Scores to Analytic MeasurementsBates K, Fernandez A, Martinez-Morilla S, Chan N, Benanto J, Reisenbichler E, Rimm D. 119 Reading vs Measuring: Comparison of Pathologist-Based Scores to Analytic Measurements. Laboratory Investigation 2025, 105: 102343. DOI: 10.1016/j.labinv.2024.102343.
• 214 Histologic Analysis and Clinical Correlation of Atypical Apocrine LesionsPodany P, Zhan H, Cartagena L, Krishnamurti U, Liang Y. 214 Histologic Analysis and Clinical Correlation of Atypical Apocrine Lesions. Laboratory Investigation 2025, 105: 102438. DOI: 10.1016/j.labinv.2024.102438.
• 437 Spatial Whole Transcriptomic Analysis Reveals Differential Gene Expression in Epithelial and Mesenchymal Components of Primary Cutaneous CarcinosarcomasHernandez S, Galan A, Lu W, Lermi N, Aung P, Kostousov L, Barnes S, Khan K, Chen K, Soto L, Nagarajan P. 437 Spatial Whole Transcriptomic Analysis Reveals Differential Gene Expression in Epithelial and Mesenchymal Components of Primary Cutaneous Carcinosarcomas. Laboratory Investigation 2025, 105: 102665. DOI: 10.1016/j.labinv.2024.102665.
• 487 Proof of Concept: Facilitating Millennials' Engagement and Actionable Education in Dermatopathology Through an International Online EventErem A, Xavier J, Galan A, Lee J. 487 Proof of Concept: Facilitating Millennials' Engagement and Actionable Education in Dermatopathology Through an International Online Event. Laboratory Investigation 2025, 105: 102716. DOI: 10.1016/j.labinv.2024.102716.
• DEVELOPMENT OF EX VIVO PATIENT-DERIVED MODELS TO UNCOVER THE TUMOR-IMMUNE MICROENVIRONMENT IN RENAL CELL CARCINOMAKashima S, Gupta R, Moritz V, Sadak K, Walker J, Adeniran A, Humphrey P, Dinulescu D, Palmer D, Hammond S, Bosenberg M, Hurwitz M, Kenney P, Braun D. DEVELOPMENT OF EX VIVO PATIENT-DERIVED MODELS TO UNCOVER THE TUMOR-IMMUNE MICROENVIRONMENT IN RENAL CELL CARCINOMA. Urologic Oncology Seminars And Original Investigations 2025, 43: 22-23. DOI: 10.1016/j.urolonc.2024.12.057.
• 831 AXL Receptor Tyrosine Kinase Expression in Metastatic Renal Cell Carcinoma: Insights from the METEOR trialLaimon Y, Paul M, Jammihal T, Ghandour F, Ahmar N, Simsek B, Matar S, Denize T, Mohanna R, De Oliveira G, Delcea A, Shukla S, Braun D, Sun M, Aftab D, Saad E, Machaalani M, Xie W, Choueiri T, Signoretti S. 831 AXL Receptor Tyrosine Kinase Expression in Metastatic Renal Cell Carcinoma: Insights from the METEOR trial. Laboratory Investigation 2025, 105: 103064. DOI: 10.1016/j.labinv.2024.103064.
• 796 Tertiary Lymphoid Structures Predict Response to First-Line Nivolumab Therapy in Advanced Renal Cell Carcinoma: Findings from the HCRN GU16-260 Clinical TrialAhmar N, Simsek B, Jegede O, Matar S, Savla V, Laimon Y, Mohanna R, De Oliveira G, Sheshdeh A, Delcea A, Paul M, Choueiri T, Xie W, Freeman G, Braun D, Haas N, Hammers H, Bilen M, Stein M, Sosman J, Wu C, McDermott D, Atkins M, Signoretti S. 796 Tertiary Lymphoid Structures Predict Response to First-Line Nivolumab Therapy in Advanced Renal Cell Carcinoma: Findings from the HCRN GU16-260 Clinical Trial. Laboratory Investigation 2025, 105: 103029. DOI: 10.1016/j.labinv.2024.103029.
• 129 Unmasking Adenomyoepithelial Lesions of the Breast: A Review of 29 CasesCartagena L, Liang Y, Zhan H, Krishnamurti U. 129 Unmasking Adenomyoepithelial Lesions of the Breast: A Review of 29 Cases. Laboratory Investigation 2025, 105: 102353. DOI: 10.1016/j.labinv.2024.102353.
• EVALUATING CLINICAL OUTCOMES AND THE ROLE OF NEOADJUVANT CHEMOTHERAPY IN PLASMACYTOID UROTHELIAL CARCINOMA: INSIGHTS FROM A COMBINED NATIONAL AND INSTITUTIONAL SERIESRahman S, Kong V, Jalfon M, Hesse D, Kim J, Wright J, Adeniran A, Humphrey P, Martin D, Ghali F. EVALUATING CLINICAL OUTCOMES AND THE ROLE OF NEOADJUVANT CHEMOTHERAPY IN PLASMACYTOID UROTHELIAL CARCINOMA: INSIGHTS FROM A COMBINED NATIONAL AND INSTITUTIONAL SERIES. Urologic Oncology Seminars And Original Investigations 2025, 43: 43. DOI: 10.1016/j.urolonc.2024.12.109.
• Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acidPan M, Zhang Y, Wright W, Liu X, Passaia B, Currier D, Low J, Chapple R, Steele J, Connelly J, Ju B, Plyler E, Lu M, Loughran A, Yang L, Abraham B, Pruett-Miller S, Freeman B, Campbell G, Dyer M, Chen T, Stewart E, Koo S, Sheppard H, Easton J, Geeleher P. Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid. Nature Communications 2025, 16: 2036. PMID: 40021625, PMCID: PMC11871043, DOI: 10.1038/s41467-025-57185-y.
• Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs MigrationXu Z, Ponek A, Thomas J, Qyang Y. Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration. ACS Sensors 2025, 10: 1722-1728. PMID: 40021359, DOI: 10.1021/acssensors.4c02793.
• Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitorsSkoulidis F, Araujo H, Do M, Qian Y, Sun X, Cobo A, Le J, Montesion M, Palmer R, Jahchan N, Juan J, Min C, Yu Y, Pan X, Arbour K, Vokes N, Schmidt S, Molkentine D, Owen D, Memmott R, Patil P, Marmarelis M, Awad M, Murray J, Hellyer J, Gainor J, Dimou A, Bestvina C, Shu C, Riess J, Blakely C, Pecot C, Mezquita L, Tabbó F, Scheffler M, Digumarthy S, Mooradian M, Sacher A, Lau S, Saltos A, Rotow J, Johnson R, Liu C, Stewart T, Goldberg S, Killam J, Walther Z, Schalper K, Davies K, Woodcock M, Anagnostou V, Marrone K, Forde P, Ricciuti B, Venkatraman D, Van Allen E, Cummings A, Goldman J, Shaish H, Kier M, Katz S, Aggarwal C, Ni Y, Azok J, Segal J, Ritterhouse L, Neal J, Lacroix L, Elamin Y, Negrao M, Le X, Lam V, Lewis W, Kemp H, Carter B, Roth J, Swisher S, Lee R, Zhou T, Poteete A, Kong Y, Takehara T, Paula A, Parra Cuentas E, Behrens C, Wistuba I, Zhang J, Blumenschein G, Gay C, Byers L, Gibbons D, Tsao A, Lee J, Bivona T, Camidge D, Gray J, Leighl N, Levy B, Brahmer J, Garassino M, Gandara D, Garon E, Rizvi N, Scagliotti G, Wolf J, Planchard D, Besse B, Herbst R, Wakelee H, Pennell N, Shaw A, Jänne P, Carbone D, Hellmann M, Rudin C, Albacker L, Mann H, Zhu Z, Lai Z, Stewart R, Peters S, Johnson M, Wong K, Huang A, Winslow M, Rosen M, Winters I, Papadimitrakopoulou V, Cascone T, Jewsbury P, Heymach J. Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors. Nature 2025, 639: e19-e19. PMID: 40016449, PMCID: PMC11903295, DOI: 10.1038/s41586-025-08767-9.
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