Tumor Profiling

Our Mission

The Tumor Profiling Laboratory at Yale-New Haven Hospital is a CLIA-certified clinical facility that performs high throughput genotyping analyses of tumor DNA to predict the sensitivity or resistance of tumors to a variety of anti-neoplastic drugs. The overall aim of the laboratory is to provide oncologists with detailed mutational profiles of their patients’ tumors so that treatment for patients may be individually optimized--a process often referred to as personalized medicine.

Our Rationale: Targeted Therapies for Cancer

The laboratory was established because of the growing number of newly developed drugs that target specific mutant proteins within malignant cells or that target critical biochemical pathways that have been altered within malignant cells as a result of mutations acquired during tumorigenesis.

Malignant cells may also possess mutations that render a tumor resistant to drug treatment, either because the mutation prevents a drug from binding to its target or because the mutation renders tumor growth independent of the protein targeted by the drug.

Tumor Genotyping Requisition Form

Testing may be ordered in EPIC or by filling out a requisition form and faxing the request to the Tumor Profiling Lab at 203-688-5588.

Tumor Sequencing

Tumor Sequencing with Ion Torrent's 409 Gene Comprehensive Cancer Panel

Tumor Sequencing with Ion Torrent's 50 Gene Hot Spot Mutation Panel 


Yale-New Haven Hospital
789 Howard Ave, CB 650
New Haven, CT 06504

Lab Phone: (203) 688-5582 or 203-688-1189
Lab Fax: (203) 688-5588
Lab Email: tumorprofilinglab@ynhh.org

Hours of Operation:
7:00 am – 4:30 pm, Mon-Fri