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Clinical Trial Tissue Services (CTTS)

Clinical Trial Tissue Services is a shared resource of Yale Cancer Center & Yale Pathology Tissue Services.


The mission of Clinical Trial Tissue Services is to provide the Yale community and clients around the world with high quality formalin-fixed paraffin embedded material (FFPE) to promote and facilitate research. Tissue is often requested for inclusion in a clinical trial, or for the correlative science associated with clinical trials requested in IRB/HIC approved protocols with specific requirements. All our tissue is handled in strict compliance with HIPAA regulations, University Research Policies, Pathology Department diagnostic requirements, and Hospital by-laws.

Services and Procedures - CTTS


It is the policy of our Department to retain all tissue blocks, so to satisfy investigators with indispensable material for research or clinical trial, we offer the following:

  • Paraffin-embedded tissue block cores ranging from 1 mm to 4 mm
  • Paraffin-embedded tissue block cores that are re-embedded into a labeled tissue block
  • Paraffin-embedded recut slides at thickness requested
  • Paraffin-embedded recut slides that are H&E stained


For each work request, a standard CTTS Work Request form must be completed by the requesting investigator. The completed form gives us your ordering and shipping information and charging instructions, as well as patient-requested tissue specifications. CTTS strives to complete all requests within a time sensitive manner.

Please email all Clinical Trial Tissue Service requests to or fax to (203) 737-8388.