Yale Hematopathology

The Hematopathology Service specializes in the evaluation of lymph nodes, bone marrow, blood, spleen, and hematolymphoid tissues in all other organs. The faculty on this service are board-certified in this subspecialty, with expertise in both anatomic and clinical pathology aspects of hematopathology. The Hematopathology team evaluates a broad range of disorders, including acute and chronic leukemias, B-cell and T-cell lymphomas, plasma cell neoplasms, myelodysplastic syndromes, myeloproliferative neoplasms, cutaneous lymphomas, and benign bone marrow and lymph node disorders. Challenging cases are discussed in detail among the expert hematopathologists at our consensus conference.

The faculty are involved nationally and internationally in professional societies and organizations to advance their field. Their academic interests are composed of a balance of clinical, basic science, and translational efforts in hematopoietic malignancies. We also offer a highly competitive fellowship in Hematopathology to two trainees each year. These are one-year fellowships that can be extended for approved research.

In addition to providing diagnostic services to Smilow Cancer Hospital, we are the primary Hematopathology specialists for surrounding hospitals, including Bridgeport Hospital, Greenwich Hospital, Milford Hospital, Griffin Hospital, and the Saint Raphael Campus of Yale New Haven Hospital.

As the diagnostic service that supports a very active bone marrow transplant service, our average turnaround time for rush biopsies is less than 24 hours. Urgent results incorporating aspirate morphology, histology, flow cytometry, immunohistochemistry, FISH/cytogenetic, and molecular results, as appropriate, are called in immediately to submitting physicians.

Our group receives external slide consultations from across the nation as well as from international sites for both primary diagnoses and second opinions. To submit slides and tissue blocks, please send to:

We work closely with our colleagues in the Clinical Hematology Laboratory and Cytogenetics Laboratory to correlate results from advanced technologies, including next-generation sequencing and array comparative genomic hybridization.