Pathology Latest News

An international team of researchers has discovered a new pathway that may improve success against an incurable type of children's brain cancer. The study results suggest that scientists have identified a unique way to disrupt the cellular process that contributes to Diffuse Intrinsic Pontine Gliomas (DIPG).

Yale School of Medicine Department of Internal Medicine’s Silvia Vilarinho, MD, PhD, assistant professor of medicine (digestive diseases) and of pathology, and Frederick Wilson, MD, PhD, assistant professor of medicine (medical oncology) and genetics, are winners of a 2019 Clinical Scientist Development Award (CSDA) from the Doris Duke Charitable Foundation (DDCF).

Dr. Richard Bucala, newly appointed as the Waldemar Von Zedtwitz Professor of Medicine, Pathology, and Epidemiology and Public Health, studies immune system regulation with a focus on how protective responses can lead to immunopathology and disease.

There’s no shame in contemplating how we managed to get around before GPS came to our phones. Some may argue that there is an overreliance on automation since maps have been a proven method of exploration and travel for centuries. Yet, access to technology like GPS has democratized travel and opened the door for society to explore our surroundings in ways few ever thought possible.

Yale pediatrician and geneticist Patrick Gallagher, M.D., studies hereditary spherocytosis (HS), an inherited disease associated with hemolytic anemia, when red blood cells are destroyed faster than they are produced due to abnormal membranes. A novel mutation in the gene that encodes alpha-spectrin, a protein essential for normal red blood cell membranes, is responsible for many cases of recessive hereditary spherocytosis (rHS), the most severe form of the disease, reports Gallagher’s team

A proposed strategy to vaccinate against Zika infection might also be effective in tackling West Nile disease, another potentially serious infection transmitted by mosquitoes, said Yale researchers in a new study.

A team led by Johns Hopkins Medicine researchers says it has identified two protein biomarkers in urine that may one day be used to better diagnose acute interstitial nephritis (AIN), an underdiagnosed but treatable kidney disorder that impairs renal function in the short term and can lead to chronic kidney disease, permanent damage or renal failure if left unchecked.

WHRY Director Carolyn M. Mazure discusses how we are at a critical point, and the scientific community needs to decide if it will embrace true transformational change in science.