2022
Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood?
Saavedra LM, Morgan-López AA, West SG, Alegría M, Silverman WK. Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood? Prevention Science 2022, 24: 1622-1635. PMID: 36057023, DOI: 10.1007/s11121-022-01422-z.Peer-Reviewed Original ResearchConceptsStudy-related treatmentYoung adulthoodPropensity scoreLong-term followDrug use disordersAdolescence/young adulthoodQuasi-experimental designLate adolescence/young adulthoodClinical trialsSubstance use disorder severityLong-term effectsChild anxiety disordersEpidemiological studiesIntegrative data analysisAnxiety disorder treatmentUse disordersDisorder treatmentAnxiety disordersControl participantsEpidemiological sampleClinical samplesDisorder severityTrialsLong-term assessmentDisorders
2016
Cross-generational influences on childhood anxiety disorders: pathways and mechanisms
Lebowitz ER, Leckman JF, Silverman WK, Feldman R. Cross-generational influences on childhood anxiety disorders: pathways and mechanisms. Journal Of Neural Transmission 2016, 123: 1053-1067. PMID: 27145763, PMCID: PMC5007197, DOI: 10.1007/s00702-016-1565-y.Peer-Reviewed Original ResearchConceptsAnxiety disordersChild anxiety treatment outcomeChild anxiety disordersChildhood anxiety disordersParent-based interventionsAnxiety treatment outcomesCross-generational influencesSocial referencingFamily accommodationChild anxietyParenting stylesVicarious learningOxytocinergic systemChildren's symptomsBehavioral systemsParental responsesParental anxietyMaternal anxietyAnxietyExistence of linksSevere distressDisordersPrenatal environmentTreatment outcomesResearchNon-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders
Lester KJ, Roberts S, Keers R, Coleman JR, Breen G, Wong CC, Xu X, Arendt K, Blatter-Meunier J, Bögels S, Cooper P, Creswell C, Heiervang ER, Herren C, Hogendoorn SM, Hudson JL, Krause K, Lyneham HJ, McKinnon A, Morris T, Nauta MH, Rapee RM, Rey Y, Schneider S, Schneider SC, Silverman WK, Smith P, Thastum M, Thirlwall K, Waite P, Wergeland GJ, Eley TC. Non-replication of the association between 5HTTLPR and response to psychological therapy for child anxiety disorders. The British Journal Of Psychiatry 2016, 208: 182-188. PMID: 26294368, PMCID: PMC4837384, DOI: 10.1192/bjp.bp.114.154997.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCBT outcomeChild anxietyAnxiety disordersChild anxiety disordersMore positive outcomesShort-allele homozygotesPositive treatment outcomesPsychological therapiesDisorder outcomesPositive outcomesTreatment studiesHomogenous sampleMixed resultsAnxietyMixed effects modelsNon-significant effectTreatment outcomesCohort 2DisordersSignificant associationFuture studiesOutcomesAssociationTherapy