2024
Associations Between Neighborhood Resources and Youth’s Response to Reward Omission in a Task Modeling Negatively Biased Environments
Brown B, Nguyen L, Morales I, Cardinale E, Tseng W, McKay C, Kircanski K, Brotman M, Pine D, Leibenluft E, Linke J. Associations Between Neighborhood Resources and Youth’s Response to Reward Omission in a Task Modeling Negatively Biased Environments. Journal Of The American Academy Of Child & Adolescent Psychiatry 2024 PMID: 38763411, DOI: 10.1016/j.jaac.2024.05.011.Peer-Reviewed Original ResearchChildhood Opportunity IndexPaper self-identifiesNeighborhood resourcesAbstractText Label="DIVERSITY &Functional magnetic resonance imagingAbstractText Label="METHOD" NlmCategory="METHODS">Ethnic groupsReward omissionBlocked goalsNeurobiological levelMood disordersNeurodevelopmental trajectoriesLocal processing modeMental healthReduced connectivityDiverse sampleInvestigate associationsControl networkNeighborhood featuresQuantify accessProvincial hubsPromote sexRewardOpportunity IndexMagnetic resonance imaging
2022
Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability
Linke J, Haller S, Xu E, Nguyen L, Chue A, Botz-Zapp C, Revzina O, Perlstein S, Ross A, Tseng W, Shaw P, Brotman M, Pine D, Gotts S, Leibenluft E, Kircanski K. Persistent Frustration-Induced Reconfigurations of Brain Networks Predict Individual Differences in Irritability. Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 62: 684-695. PMID: 36563874, PMCID: PMC11224120, DOI: 10.1016/j.jaac.2022.11.009.Peer-Reviewed Original ResearchConceptsResting-state scansPathophysiology of irritabilitySelf-reported irritabilityFunctional magnetic resonance imagingMagnetic resonance imagingParent-reported irritabilitySpecific intervention targetsRisk factorsMotor functionPsychiatric consultationCircuit reorganizationCommon reasonAffective disordersBrain network configurationIrritability symptomsResonance imagingBrain regionsIrritabilityCentral mechanismsAberrant responsesPilot studyIntervention targetsRecovery periodPediatric irritabilityBrain networks
2020
Fixel-Based Diffusion Magnetic Resonance Imaging Reveals Novel Associations Between White Matter Microstructure and Childhood Aggressive Behavior
Grazioplene R, Tseng WL, Cimino K, Kalvin C, Ibrahim K, Pelphrey KA, Sukhodolsky DG. Fixel-Based Diffusion Magnetic Resonance Imaging Reveals Novel Associations Between White Matter Microstructure and Childhood Aggressive Behavior. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2020, 5: 490-498. PMID: 32144044, PMCID: PMC7214205, DOI: 10.1016/j.bpsc.2019.12.018.Peer-Reviewed Original ResearchConceptsWhite matter densityCorpus callosumFiber densityAggressive behaviorCingulum bundleAbnormal interhemispheric connectivityHealthy control childrenWhite matter abnormalitiesAttention-deficit/hyperactivity disorderMiddle cerebellar peduncleSuperior thalamic radiationMagnetic resonance imagingInferior fronto-occipital fasciculusWhole-brain analysisInferior longitudinal fasciculusFronto-occipital fasciculusPotential neural mechanismsWhite matter microstructureDiffusion magnetic resonance imagingInterhemispheric connectivityCortical pathwaysCerebellar peduncleChild Behavior ChecklistThalamic radiationFiber bundle density