2001
Elevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation
Boutros N, Lisanby S, Tokuno H, Torello M, Campbell D, Berman R, Malison R, Krystal J, Kosten T. Elevated motor threshold in drug-free, cocaine-dependent patients assessed with transcranial magnetic stimulation. Biological Psychiatry 2001, 49: 369-373. PMID: 11239908, DOI: 10.1016/s0006-3223(00)00948-3.Peer-Reviewed Original ResearchConceptsTranscranial magnetic stimulationCortical excitabilityCocaine-dependent subjectsMotor thresholdControl subjectsMagnetic stimulationSingle-pulse transcranial magnetic stimulationExcitatory/inhibitory balancePulse transcranial magnetic stimulationChronic cocaine abuseMotor cortical regionsChronic cocaine abusersNormal control subjectsNumber of neurotransmittersAlters cortical excitabilityCocaine-dependent patientsCortical inhibitoryCerebral cortexInhibitory balanceAwake subjectsChronic cocaineCocaine intoxicationCocaine abusePsychiatric populationsCortical regions
1999
Comparison of four components of sensory gating in schizophrenia and normal subjects: a preliminary report
Boutros N, Belger A, Campbell D, D’Souza C, Krystal J. Comparison of four components of sensory gating in schizophrenia and normal subjects: a preliminary report. Psychiatry Research 1999, 88: 119-130. PMID: 10622348, DOI: 10.1016/s0165-1781(99)00074-8.Peer-Reviewed Original ResearchConceptsNormal control subjectsSchizophrenia patientsSensory gatingControl subjectsNormal subjectsSex-matched normal control subjectsPathophysiology of schizophreniaStimulus repetitionStable schizophrenia patientsSchizophrenia subjectsSimilar abnormalitiesPatientsPreliminary reportDysfunctionDegree of attenuationSchizophreniaLate phaseSubjectsDeviant stimuliStimulus changeIrrelevant stimuliPathophysiologyStimuliPotential paradigmAbnormalities