2016
Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in Rodents
Dwyer JB, Leslie FM. Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in Rodents. PLOS ONE 2016, 11: e0146966. PMID: 26784516, PMCID: PMC4718668, DOI: 10.1371/journal.pone.0146966.Peer-Reviewed Original ResearchConceptsD1/D2 interactionsImmediate early genesIEG expressionD2 receptor functionCommon neurobiological substrateMesocorticolimbic dopamine systemDopamine receptor bindingStress-related circuitryIllicit drug useFunctional neural circuitryAge-dependent changesDrugs of abuseD2 agonistDopamine D1Bed nucleusStria terminalisAdult ratsPharmacological actionsDopamine systemDrug useLow dosesBNST functionDirect D1Neuropsychiatric disordersReceptor function
2010
Adolescent Maturation of D1 and D2 Dopamine Receptor Interactions
Dwyer J, Martinez L, Ganddini G, Perez M, Leslie F. Adolescent Maturation of D1 and D2 Dopamine Receptor Interactions. The FASEB Journal 2010, 24: 766.1-766.1. DOI: 10.1096/fasebj.24.1_supplement.766.1.Peer-Reviewed Original ResearchD1/D2 interactionsDopamine receptor interactionsMesocorticolimbic dopamine systemImmediate early gene expressionDopaminergic drugsReceptor changesD2 agonistDirect agonistsIndirect agonistsAdult ratsLimbic systemDopamine systemDirect D1Neuropsychiatric disordersEarly gene expressionFunctional connectivityNeural circuitryDA systemBehavioral responsesAgonistsC-fosAge differencesPhRMA FoundationAdolescent maturationReceptor interaction