1984
Selective prefrontal cortical projections to the region of the locus coeruleus and raphe nuclei in the rhesus monkey
Arnsten A, Goldman-Rakic PS. Selective prefrontal cortical projections to the region of the locus coeruleus and raphe nuclei in the rhesus monkey. Brain Research 1984, 306: 9-18. PMID: 6466989, DOI: 10.1016/0006-8993(84)90351-2.Peer-Reviewed Original ResearchConceptsRaphe nucleusLocus coeruleusDorsal prefrontal cortexInferior temporal gyrusCortical areasPrefrontal cortexCortical projectionsRhesus monkeysTemporal gyrusAnterograde labeling techniquesCentral superior raphe nucleiPrefrontal cortical projectionsNoradrenergic locus coeruleusContralateral locus coeruleusParietal association cortexSuperior raphe nucleusDorsolateral prefrontal cortexSerotonergic dorsalLabeled fibersCerebral cortexCortical injectionsOrbital prefrontal cortexMonoaminergic innervationRaphe regionSomatosensory cortex
1981
Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior
Arnsten A, Segal DS, Loughlin SE, Roberts D. Evidence for an interaction of opioid and noradrenergic locus coeruleus systems in the regulation of environmental stimulus-directed behavior. Brain Research 1981, 222: 351-363. PMID: 7284783, DOI: 10.1016/0006-8993(81)91038-6.Peer-Reviewed Original ResearchConceptsOpiate agonist morphineNoradrenergic locus coeruleus systemOpiate antagonist naloxoneDorsal bundleSham-lesioned ratsLocus coeruleus systemLocus coeruleus activityStimulus contactStimulus interactionAgonist morphineAntagonist naloxoneOpioid roleInhibitory actionNaloxoneOpioidsReportParticular environmental stimuliMorphineLesionsRats