Yale Researchers Take Stem Cells One Step Closer to Replacing Parathyroid Gland Function
Yale investigators have developed a multistep process that models the biological instructions to create parathyroid gland cells from pluripotent stem cells, a significant milestone along the path toward helping people who lack the hormones released by parathyroid glands.
Bio Haven: How Yale and New Haven are building a future together
New Haven’s biotech community has seen fits and starts, but today it is achieving critical mass. Upwards of 50 biotech and medical device companies employ more than 5,000 people in greater New Haven. Yale School of Medicine has been instrumental in the communty's growth.
Yale Stem Cell Center will host two-day symposium to celebrate its 10th anniversary
Since it was founded in 2006, the Yale Stem Cell Center has supported the ground-breaking work of researchers and scientists working in basic stem cell research and translational science. On Thursday, Nov. 10, and Friday, Nov. 11, the center will hold a symposium in honor of its 10th anniversary.
Medulloblastoma patients should receive both chemotherapy and radiation post-surgery
In a recent study, a Yale Cancer Center team revealed that the addition of chemotherapy to postoperative treatment for adults with medulloblastoma improves survival. The benefit of chemotherapy, in addition to craniospinal radiation, was seen in adult patients with medulloblastoma (MB), including those with localized disease who received high-dose radiation treatment following surgery. The findings were presented September 26 at the American Society for Therapeutic Radiology and Oncology (ASTRO) meeting in Boston.
Trace elements: Innovative biopsy programs map how cancer spreads
When doctors do take biopsies, they want to do so in a way that is safest for patients, says Roy Herbst, a lung cancer oncologist at the Yale School of Medicine in New Haven. In lung cancer, for example, the oncologist might choose not to take biopsies of metastases from the liver, because these extra biopsies could lead to bleeding complications. “Remember, you are sticking a needle through the skin using guided imaging for most of these,” Herbst says.Source: Nature Medicine
Center provides researchers access to highly specialized tools
If a researcher needs highly the specialized expertise and equipment required to investigate a blood disease, where does she go? Answer: the Yale Cooperative Center of Excellence in Hematology Specialized Core Center (YCCEH). The National Institutes of Health has designated Yale as one of three universities nationwide to receive a $5 million, five-year grant. The others include the University of Washington and Indiana University.
Research in the News: Study uncovers potential to alleviate tissue damage during strokes or transplant
A new study from Yale School of Medicine uncovers clues as to how a key part of the immune system is regulated to avoid tissue injury to human organs after stroke or transplant. The study, in the journal Developmental Cell, focuses on a type of white blood cell called a neutrophil, and how regulation of the granules inside can protect organs such as kidneys from injury.
Get to know the speaker of our Cell Biology Seminar series! An interview with Dr. Sara Wickström (MD PhD)
Exciting, interesting cutting edge science talks are featured in our seminar series! Along with the scientific story that has to be told, there is also the story of our great guest speakers! How did it start? How is it going? Follow our series on “Get to know the Speaker!” The first speaker was Dr. S. Wickström (MD PhD) from the University of Helsinki.
Simple Change to Microscope Opens Up a Complex Panorama of Cells
Yale researchers in the lab of Joerg Bewersdorf have developed a way to visualize extremely tiny structures by using standard light microscopy, a world previously only accessible by expensive and cumbersome electron microscopy.Source: YaleNews
Position Openings in the Zhang lab
The Zhang lab at the Department of Cell Biology, Yale University, uses single-molecule approaches, especially high-resolution optical tweezers, to study folding dynamics of proteins involved in fundamental biological processes and human diseases. The lab is now seeking graduate students and postdocs for research in the following three areas: • Regulated SNARE folding and assembly. • Membrane protein folding, stability, and protein-membrane interactions. • Instrumental development. Prior research experience in single-molecule biophysics is not required. However, postdoc candidates should have strong quantitative skills and solid training in biophysics, molecular biology, or physics. If you are interested in these positions, please contact Dr. Yongli Zhang at firstname.lastname@example.org.
Scientists find many gene 'drivers' of cancer, but warn: Don't ignore 'passengers'
A massive analysis of the entire genomes of 2,658 people with 38 different types of cancer has identified mutations in 179 genes and gene regulators as “drivers” — variations in DNA sequences that lead to the development of cancer.
In the right (lab) culture, mentorship flourishes — and science benefits
You might imagine a science lab looking a bit sterile and impersonal — little sunlight, masked figures in white coats pouring neon-colored liquid into beakers, all business. You might not expect to hear a science lab referred to as familial, where badminton tournaments, movie nights and barbeques are commonplace.
Colón-Ramos named McConnell Duberg Associate Professor
Daniel A. Colón-Ramos, PhD, recently appointed as Dorys McConnell Duberg Associate Professor of Neuroscience and Cell Biology, focuses his research on how synapses are formed and maintained to control behavior and store memories. Colón-Ramos’ discoveries have altered long-held views on the process and may offer important clues in the fight against disease.
Study Explores Role of Metabolism in Immune Cell Behavior
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.