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Excellence in clinical care stems from advances in understanding the fundamental basis for abnormalities of the nervous system and the resulting development of new and more effective treatment strategies for nervous system disorders. For this reason, research remains an integral part of the Department of Neurology. Members of the faculty in Neurology have a broad range of research interests that span the areas of molecular biology, electrophysiology, biophysics, pharmacology, molecular genetics, immunopathology, neurotransplantation and computational neuroscience as pertaining to nervous system disorders.

The Department is highly committed to translation of basic research findings to the clinical domain and actively promotes productive interactions between clinicians and basic scientists, and provides resources for collaborative translational studies. Members of the faculty include world-renowned leaders in their fields of research who continue significantly to enhance the understanding of the nervous system and its disorders.

Clinical Research

Department of Neurology Annual Report 2020-2022

Introducing the Yale Department of Neurology 2020-2022 annual report, a comprehensive overview of our Education, Diversity, and Wellness Efforts, as well as clinical, research, and patient care updates from each division. YSM Neurology is a world-renowned research, teaching, and clinical center devoted to exceptional patient care; education of medical and graduate students; and neurological research.

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National Neurology Research Networks


INFINITY (Investigations for Improved Neurological Treatments at Yale) was selected in 2018 by the National Institutes of Neurological Disorders and Stroke (NINDS) as one of approximately 25 U.S. sites designated to participate in the Network of Excellence in Neuroscience Clinical Trials (NeuroNEXT). This network conducts both biomarker validations and Phase 2 studies of treatment for neurological disease in adults and children through partnerships with academic, private foundations, and industry.


SPIRIT (Southern New England Partnership in Stroke Research, Innovation and Treatment) was selected in 2018 by the National Institutes of Health (NIH) as one of approximately 25 U.S. sites designated to participate in StrokeNET. The primary goal of this network is to maximize efficiencies to develop, promote, and conduct high-quality, multi-site clinical trials focused on key interventions in stroke prevention, treatment, and recovery.