Labs
- Magnetic Resonance Imaging LabTodd Constable, PhD, director
- Clinical Chemistry LaboratoryTore Eid, MD, PhD, associate director
- Yale Positron Emission Tomography (PET) Research CenterRichard Carson, PhD, director
- Yale Clinical Neuroscience NeuroanalyticsDennis Spencer, MD; Mohsen Nami, PhD; Hitten Zaveri, PhD; Tore Eid, MD, PhD
Clinical Trial
Hamada Hamid Altalib
Human Epilepsy Project 3: Newly Diagnosed Idiopathic Generalized Epilepsy
- Ages13 years and older
- GenderBoth
Clinical Trial
David King-Stephens
Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval Study (EPAS)
- Ages18 years and older
- GenderBoth
Clinical Trial
Lawrence Hirsch
A double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of intravenous ganaxolone in status epilepticus (RAISE)
- Ages12 years and older
- GenderBoth
Clinical Trial
Hal Blumenfeld
Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy (START)
- Ages18 years - 75 years
- GenderBoth
Clinical Trial
David King-Stephens
A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
- Ages12 years and older
- GenderBoth
Clinical Trial
David King-Stephens
An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
- Ages12 years and older
- GenderBoth
Clinical Trial
Imran Quraishi
RNS® System Post-Approval Study in Epilepsy
- Ages18 years and older
- GenderBoth
Clinical Trial
Richard Carson
SV2A PET Imaging in Healthy Subjects and Epilepsy Patients
- Ages18 years - 90 years
- GenderBoth
Clinical Trial
Adithya Sivaraju
Post Acute Symptomatic Seizure Investigation and Outcomes Network (PASSION)
Research Collaborators
Professor Emeritus of Neurosurgery
Research Interests- Brain
- Epilepsy
- Nervous System
- Neurobiology
- Neurosurgery
- Seizures
- Trauma, Nervous System
Dr. Nihal C. de Lanerolle holds the rank of Professor of Neurosurgery and Neurobiology. A Fulbright Senior Scholar and Corresponding Member of the German League Against Epilepsy, he is the recipient of the higher doctoral degree of Doctor of Science from the University of Sussex, England. He has served as a Member of the National Institute of Mental Health study Section on "Cognitive Functional Neuroscience", as a Member of the "Sensory, Motor and Cognitive Neuroscience Fellowships Study Section and the Study Section on Traumatic Brain Injury, CDMRP Department of Defense. An expert on the neuropathology of human seizure foci and explosive blast traumatic brain injury, Dr. de Lanerolle participates in national and international symposia on epilepsy and traumatic brain injury, and regularly as a reviewer of manuscripts for leading scientific journals. He is member of the Yale Epilepsy Surgery Research Program and the Yale Interdepartmental Neuroscience Graduate Program and is active as a teacher of neuroscience to medical students and undergraduates.Professor of Pharmacology and of Cellular And Molecular Physiology
Research Interests- Ion Channels
- Learning
- Memory
- Neurosciences
- Pharmacology
- Physiology
Dr. Kaczmarek carried out his undergraduate and graduate work at the University of London. He continued his research career at the University of California Los Angeles (where he learned electrophysiology), the Free University of Brussels, Belgium (where he learned how to make neural network models) and the California Institute of Technology (where he made the fundamental discovery that phosphorylation state changes ionic currents) before joining the Yale faculty in 1981. The Kaczmarek group studies biochemical changes in neurons that result in prolonged changes in the behavior of an animal or detect specific patterns of sensory inputs. He is well-known for discovering the genes for several ion channel proteins that are directly responsible for the excitability of nerve cells. His work was the first to demonstrate directly that rapid changes in phosphorylation state of ion channels occur in vivo in response to changes in the animal’s environment. Currently his lab is focused on the way mutations in these proteins may be responsible for several forms of intellectual disability and autism. He has been very fortunate to have many exceptionally talented pre- and postdoctoral trainees in his laboratory. Thirty-two of the students and postdocs from the Kaczmarek laboratory have gone on to hold tenure-track faculty positions at major institutions including Brown University, Yale University, UCSF, UCSD, Vanderbilt and many more.