Publications

2025

• Efficacité et tolérance du nipocalimab chez les patients atteints de myasthénie auto-immune généralisée : résultats de Vivacity-MG3, une étude de phase 3 en double aveugle randomisée et contrôlée par placeboVu T, Antozzi C, Ramchandren S, Nowak R, Farmakidis C, Bril V, Lucas A. Efficacité et tolérance du nipocalimab chez les patients atteints de myasthénie auto-immune généralisée : résultats de Vivacity-MG3, une étude de phase 3 en double aveugle randomisée et contrôlée par placebo. Revue Neurologique 2025, 181: s112. DOI: 10.1016/j.neurol.2025.01.219.
• Incidence of Dysphagia and Comorbidities in Patients with Cervical Dystonia, Analyzed by Botulinum Neurotoxin Treatment ExposureBarbano R, Jabbari B, Sadeghi M, Ukah A, Yue E, Ifantides K, Huang N, Swope D. Incidence of Dysphagia and Comorbidities in Patients with Cervical Dystonia, Analyzed by Botulinum Neurotoxin Treatment Exposure. Toxins 2025, 17: 148. PMID: 40137921, PMCID: PMC11945862, DOI: 10.3390/toxins17030148.
• Benzodiazepine Initiation and the Risk of Falls or Fall-Related Injuries in Older Adults Following Acute Ischemic StrokeSun S, Lomachinsky V, Smith L, Newhouse J, Westover M, Blacker D, Schwamm L, Haneuse S, Moura L. Benzodiazepine Initiation and the Risk of Falls or Fall-Related Injuries in Older Adults Following Acute Ischemic Stroke. Neurology Clinical Practice 2025, 15: e200452. PMID: 40144887, DOI: 10.1212/cpj.0000000000200452.
• The neuropathologic basis for translational biomarker development in the macaque model of late-onset Alzheimer's disease.Zeiss C, Huttner A, Nairn A, Arnsten A, Datta D, Strittmatter S, Wyk B, Duque A. The neuropathologic basis for translational biomarker development in the macaque model of late-onset Alzheimer's disease. Journal Of Alzheimer's Disease 2025, 13872877251323787. PMID: 40095666, DOI: 10.1177/13872877251323787.
• Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical TrialPatel R, Kumskova M, Kodali H, Budnik I, Kuznetsov V, Jain A, Jha A, Thedens D, Dhanesha N, Sutariya B, Nagarkatti K, Lamb J, Kamat P, Shi Y, Avery B, Imai T, Jin X, Chauhan A, Boisserand L, Khan M, Dhandapani K, Sanganahalli B, Sansing L, Hess D, Koehler R, McCullough L, Aronowski J, Ayata C, Diniz M, Lyden P, Planas A, Chamorro A, Chauhan A, Leira E, Investigators O. Uric Acid Stroke Cerebroprotection Transcended Sex, Age, and Comorbidities in a Multicenter Preclinical Trial. Stroke 2025, 56: 965-973. PMID: 40091742, DOI: 10.1161/strokeaha.124.048748.
• In Vitro Inhibition of Voltage-Dependent Sodium Currents by the Antifungal Drug AmorolfineGhovanloo M, Tyagi S, Effraim P, Waxman S. In Vitro Inhibition of Voltage-Dependent Sodium Currents by the Antifungal Drug Amorolfine. Journal Of Biological Chemistry 2025, 108407. PMID: 40090585, DOI: 10.1016/j.jbc.2025.108407.
• Protocol and design of the REPOSE study: a double-blinded, randomised, placebo-controlled trial to evaluate the efficacy of suvorexant to improve postoperative sleep and reduce delirium severity in older patients undergoing non-cardiac surgeryFallon J, Hashemaghaie M, Peterson C, Tran D, Wu S, Valdes J, Pedicini N, Adams M, Soltis M, Mansour W, Wright M, Raghunathan K, Treggiari M, Sasannejad C, Devinney M. Protocol and design of the REPOSE study: a double-blinded, randomised, placebo-controlled trial to evaluate the efficacy of suvorexant to improve postoperative sleep and reduce delirium severity in older patients undergoing non-cardiac surgery. BMJ Open 2025, 15: e091099. PMID: 40081971, PMCID: PMC11907038, DOI: 10.1136/bmjopen-2024-091099.
• Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer’s diseaseCai Y, Kanyo J, Wilson R, Bathla S, Cardozo P, Tong L, Qin S, Fuentes L, Pinheiro-de-Sousa I, Huynh T, Sun L, Mansuri M, Tian Z, Gan H, Braker A, Trinh H, Huttner A, Lam T, Petsalaki E, Brennand K, Nairn A, Grutzendler J. Subcellular proteomics and iPSC modeling uncover reversible mechanisms of axonal pathology in Alzheimer’s disease. Nature Aging 2025, 5: 504-527. PMID: 40065072, PMCID: PMC11922768, DOI: 10.1038/s43587-025-00823-3.
• Reduced removal of waste products from energy metabolism takes center stage in human brain agingMangia S, DiNuzzo M, Ponticorvo S, Dienel G, Behar K, Benveniste H, Hyder F, Giove F, Herculano-Houzel S, Petroff O, Eberly L, Filip P, Michaeli S, Rothman D. Reduced removal of waste products from energy metabolism takes center stage in human brain aging. Scientific Reports 2025, 15: 8127. PMID: 40057554, PMCID: PMC11890754, DOI: 10.1038/s41598-025-90342-3.
• Voxel-Wise Map of Intracerebral Hemorrhage Locations Associated With Worse OutcomesKaram G, Chen M, Zeevi D, Harms B, Berson E, Torres-Lopez V, Rivier C, Malhotra A, Qureshi A, Falcone G, Sheth K, Payabvash S. Voxel-Wise Map of Intracerebral Hemorrhage Locations Associated With Worse Outcomes. Stroke 2025, 56: 868-877. PMID: 40052269, DOI: 10.1161/strokeaha.124.048453.
• The Safety Profile of Pridopidine, a Novel Sigma-1 Receptor Agonist for the Treatment of Huntington’s DiseaseGoldberg Y, Navon-Perry L, Cruz-Herranz A, Chen K, Hecker-Barth G, Spiegel K, Cohen Y, Niethammer M, Tan A, Schuring H, Geva M, Hayden M. The Safety Profile of Pridopidine, a Novel Sigma-1 Receptor Agonist for the Treatment of Huntington’s Disease. CNS Drugs 2025, 1-14. PMID: 40055280, DOI: 10.1007/s40263-025-01171-x.
• Education Research: The Landscape of Adult Neurology Residency Didactic Curricula in the United States: A Cross-Sectional Survey.Sutherland H, Gummerson C, Encandela J, Nascimento F, Moeller J. Education Research: The Landscape of Adult Neurology Residency Didactic Curricula in the United States: A Cross-Sectional Survey. Neurology Education 2025, 4: e200205. PMID: 40104778, PMCID: PMC11919388, DOI: 10.1212/ne9.0000000000200205.
• Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratificationD'Aoust T, Clocchiatti‐Tuozzo S, Rivier C, Mishra A, Hachiya T, Grenier‐Boley B, Soumaré A, Duperron M, Le Grand Q, Bouteloup V, Proust‐Lima C, Samieri C, Neuffer J, Sargurupremraj M, Chêne G, Helmer C, Thibault M, Amouyel P, Lambert J, Kamatani Y, Jacqmin‐Gadda H, Tregouët D, Inouye M, Dufouil C, Falcone G, Debette S. Polygenic score integrating neurodegenerative and vascular risk informs dementia risk stratification. Alzheimer's & Dementia 2025, 21: e70014. PMID: 40042447, PMCID: PMC11881617, DOI: 10.1002/alz.70014.
• Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis.Manning A, Letchuman V, Martin M, Gombos E, Robert-Fitzgerald T, Cao Q, Raza P, O'Donnell C, Renner B, Daboul L, Rodrigues P, Ramos M, Derbyshire J, Azevedo C, Bar-Or A, Caverzasi E, Calabresi P, Cree B, Freeman L, Henry R, Longbrake E, Oh J, Papinutto N, Pelletier D, Samudralwar R, Suthiphosuwan S, Schindler M, Bilello M, Song J, Sotirchos E, Sicotte N, Al-Louzi O, Solomon A, Reich D, Ontaneda D, Sati P, Shinohara R. Multicenter Automated Central Vein Sign Detection Performs as Well as Manual Assessment for the Diagnosis of Multiple Sclerosis. American Journal Of Neuroradiology 2025, 46: 620-626. PMID: 39332906, DOI: 10.3174/ajnr.a8510.
• Evolution of EEG Findings in Patients with Acute Brain InjuryNarrett J, Byrnes M, Gilmore E, Hirsch L, Punia V, Sivaraju A. Evolution of EEG Findings in Patients with Acute Brain Injury. Neurocritical Care 2025, 1-8. PMID: 40038178, DOI: 10.1007/s12028-025-02227-y.
• Research Priorities in Neuropalliative CareLau W, Fehnel C, Macchi Z, Mehta A, Auffret M, Bogetz J, Fleisher J, Graber J, Leeper H, Manglani-Terranova H, Muehlschlegel S, Mroz E, Pedowitz E, Ramanathan U, Sarmet M, Shlobin N, Sokol L, Weeks S, Xu J, Medsger H, Creutzfeldt C, Vranceanu A, Zahuranec D, Hwang D. Research Priorities in Neuropalliative Care. JAMA Neurology 2025, 82: 295-302. PMID: 39899319, DOI: 10.1001/jamaneurol.2024.4932.
• Apixaban to Prevent Covert Infarcts After Cryptogenic Stroke in Patients With Atrial CardiopathyLansberg M, Wintermark M, Chen H, Howard G, Cassarly C, Pauls Q, Kemp S, Harris T, Krishnaiah B, Stanton R, Lyerly M, Miller B, Smith E, Tirschwell D, Sheth K, Kamel H, Longstreth W, Elkind M, Broderick J, Lazar R. Apixaban to Prevent Covert Infarcts After Cryptogenic Stroke in Patients With Atrial Cardiopathy. JAMA Neurology 2025, 82: 220-227. PMID: 39869342, PMCID: PMC11773411, DOI: 10.1001/jamaneurol.2024.4838.
• Composition and function of AChR chimeric autoantibody receptor T cells for antigen-specific B cell depletion in myasthenia gravisOh S, Khani-Habibabadi F, O'Connor K, Payne A. Composition and function of AChR chimeric autoantibody receptor T cells for antigen-specific B cell depletion in myasthenia gravis. Science Advances 2025, 11: eadt0795. PMID: 40020066, PMCID: PMC11870065, DOI: 10.1126/sciadv.adt0795.
• diAcCA, a Pro-Drug for Carnosic Acid That Activates the Nrf2 Transcriptional Pathway, Shows Efficacy in the 5xFAD Transgenic Mouse Model of Alzheimer’s DiseaseBanerjee P, Wang Y, Carnevale L, Patel P, Raspur C, Tran N, Zhang X, Natarajan R, Roberts A, Baran P, Lipton S. diAcCA, a Pro-Drug for Carnosic Acid That Activates the Nrf2 Transcriptional Pathway, Shows Efficacy in the 5xFAD Transgenic Mouse Model of Alzheimer’s Disease. Antioxidants 2025, 14: 293. PMCID: PMC11939361, DOI: 10.3390/antiox14030293.
• Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern.Kiriakopoulos E, Chu F, Salpekar J, Baslet G, Ghearing G, Altalib H, Sajatovic M. Psychosocial Burden and Suicidality in Epilepsy: A Public Health Concern. Epilepsy Currents 2025, 15357597251318577. PMID: 40028187, PMCID: PMC11869224, DOI: 10.1177/15357597251318577.
• Deleting My Mother’s Email AccountRosenblum D. Deleting My Mother’s Email Account. JAMA 2025, 333: 1036-1036. PMID: 40014360, DOI: 10.1001/jama.2025.0136.
• S-Nitrosylation of CRTC1 in Alzheimer’s disease impairs CREB-dependent gene expression induced by neuronal activityZhang X, Vlkolinsky R, Wu C, Dolatabadi N, Scott H, Prikhodko O, Zhang A, Blanco M, Lang N, Piña-Crespo J, Nakamura T, Roberto M, Lipton S. S-Nitrosylation of CRTC1 in Alzheimer’s disease impairs CREB-dependent gene expression induced by neuronal activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2025, 122: e2418179122. PMID: 40014571, PMCID: PMC11892585, DOI: 10.1073/pnas.2418179122.
• Efficacy and safety of intravenous alteplase for unknown onset stroke on prior antiplatelet therapy: Post hoc analysis of the EOS individual participant data.Shiomi Y, Miwa K, Jensen M, Inoue M, Yoshimura S, Kamogawa N, Fukuda-Doi M, Ma H, Ringleb P, Wu O, Schwamm L, Davis S, Donnan G, Gerloff C, Nakahara J, Toyoda K, Thomalla G, Koga M. Efficacy and safety of intravenous alteplase for unknown onset stroke on prior antiplatelet therapy: Post hoc analysis of the EOS individual participant data. International Journal Of Stroke 2025, 17474930251322034. PMID: 39921231, DOI: 10.1177/17474930251322034.
• A compendium of human gene functions derived from evolutionary modellingRamsey J, Siegele D, Chisholm R, Fey P, Giglio M, Nadendla S, Antonazzo G, Attrill H, Brown N, Garapati P, Marygold S, Ahmed S, Asanitthong P, Buitrago D, Erdol M, Gage M, Huang S, Kadhum M, Li K, Long M, Michalak A, Pesala A, Pritazahra A, Saverimuttu S, Su R, Xu Q, Lovering R, Blake J, Christie K, Corbani L, Dolan M, Ni L, Sitnikov D, Smith C, Lera-Ramirez M, Rutherford K, Wood V, D’Eustachio P, Demos W, De Pons J, Dwinell M, Hayman G, Kaldunski M, Kwitek A, Laulederkind S, Smith J, Tutaj M, Vedi M, Wang S, Engel S, Karra K, Miyasato S, Nash R, Skrzypek M, Weng S, Wong E, Achsel T, Andres-Alonso M, Bagni C, Bayés À, Biederer T, Brose N, Chua J, Coba M, Cornelisse L, de Juan-Sanz J, Goldschmidt H, Gundelfinger E, Huganir R, Imig C, Jahn R, Jung H, Kaeser P, Kim E, Koopmans F, Kreutz M, Lipstein N, MacGillavry H, McPherson P, O’Connor V, Pielot R, Ryan T, Sala C, Sheng M, Smalla K, Smit A, Toonen R, van Weering J, Verhage M, Verpelli C, Bakker E, Berardini T, Reiser L, Auchincloss A, Axelsen K, Argoud-Puy G, Blatter M, Boutet E, Breuza L, Bridge A, Casals-Casas C, Coudert E, Estreicher A, Famiglietti M, Gos A, Gruaz-Gumowski N, Hulo C, Hyka-Nouspikel N, Jungo F, Le Mercier P, Lieberherr D, Masson P, Morgat A, Pedruzzi I, Pourcel L, Poux S, Rivoire C, Sundaram S, Bowler-Barnett E, Bye-A-Jee H, Denny P, Ignatchenko A, Ishtiaq R, Lock A, Lussi Y, Magrane M, Martin M, Orchard S, Raposo P, Speretta E, Tyagi N, Warner K, Zaru R, Chan J, Diamantakis S, Raciti D, Fisher M, James-Zorn C, Ponferrada V, Zorn A, Ramachandran S, Ruzicka L, Westerfield M. A compendium of human gene functions derived from evolutionary modelling. Nature 2025, 1-9. PMID: 40011791, DOI: 10.1038/s41586-025-08592-0.
• Longitudinal CNS and systemic T-lymphocyte and monocyte activation before and after antiretroviral therapy beginning in primary HIV infectionChan P, Li X, Li F, Emu B, Price R, Spudich S. Longitudinal CNS and systemic T-lymphocyte and monocyte activation before and after antiretroviral therapy beginning in primary HIV infection. Frontiers In Immunology 2025, 16: 1531828. PMID: 40070827, PMCID: PMC11893981, DOI: 10.3389/fimmu.2025.1531828.
• Cortical Dysplasia Beyond mTOR: Cellular Senescence Takes a TollZhan Y, Zhou J, Zheng G, Zheng Y. Cortical Dysplasia Beyond mTOR: Cellular Senescence Takes a Toll. Neuroscience Bulletin 2025, 1-4. PMID: 39987426, DOI: 10.1007/s12264-025-01365-9.
• Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in ThailandOcampo F, Sacdalan C, Pinyakorn S, Paudel M, Wansom T, Poltubtim N, Sriplienchan S, Phanuphak N, Paul R, Hsu D, Colby D, Trautmann L, Spudich S, Chan P. Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand. AIDS Research And Therapy 2025, 22: 20. PMID: 39972347, PMCID: PMC11841302, DOI: 10.1186/s12981-025-00707-x.
• Fever Prevention in Acute Vascular Brain Injury—ReplyGreer D, Sheth K. Fever Prevention in Acute Vascular Brain Injury—Reply. JAMA 2025, 333: 636-636. PMID: 39841455, DOI: 10.1001/jama.2024.25530.
• Understanding Patient Referral Practices and Perceptions of Mental Health Professionals Among NeurologistsGopaul M, Chiraroekmongkon S, Altalib H. Understanding Patient Referral Practices and Perceptions of Mental Health Professionals Among Neurologists. Neurology Clinical Practice 2025, 15: e200455. PMID: 39980575, PMCID: PMC11839230, DOI: 10.1212/cpj.0000000000200455.
• SUSCEPTIBLE PYRAMIDAL NEURONS IN PRIMATE DORSOLATERAL PREFRONTAL CORTEX EXPRESS AN ENRICHED CALCIUM INTERACTOME: CRITICAL ROLE OF CALBINDIN AND CAV1.2 IN HIGHER-ORDER COGNITIONDatta *, Yang S, Joyce M, Woo E, McCarroll S, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman R, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O'dell R, van Dyck C, Lewis D, Wang M, Krienen F, Arnsten A. SUSCEPTIBLE PYRAMIDAL NEURONS IN PRIMATE DORSOLATERAL PREFRONTAL CORTEX EXPRESS AN ENRICHED CALCIUM INTERACTOME: CRITICAL ROLE OF CALBINDIN AND CAV1.2 IN HIGHER-ORDER COGNITION. The International Journal Of Neuropsychopharmacology 2025, 28: i57-i58. PMCID: PMC11814899, DOI: 10.1093/ijnp/pyae059.100.
• Silent Myocardial Infarction and Risk of Stroke Recurrence: A Post Hoc Analysis of the IRIS Trial.Ridha M, Zhang C, McCullough S, Viscoli C, Sharma R, Kamel H, Merkler A. Silent Myocardial Infarction and Risk of Stroke Recurrence: A Post Hoc Analysis of the IRIS Trial. Journal Of The American Heart Association 2025, 14: e037663. PMID: 39921499, DOI: 10.1161/jaha.124.037663.
• Spatial Correlates of Dementia and Disability After Intracerebral Hemorrhage.Chen Y, Rivier C, Mora S, Torres Lopez V, Payabvash S, Sheth K, Harloff A, Falcone G, Rosand J, Mayerhofer E, Anderson C. Spatial Correlates of Dementia and Disability After Intracerebral Hemorrhage. Journal Of The American Heart Association 2025, 14: e037930. PMID: 39921496, DOI: 10.1161/jaha.124.037930.
• Impaired creatinine-based estimated glomerular filtration rate in Thai individuals switching to dolutegravir: illustrating the role of cystatin C testing to aid clinical decision making.Sacdalan C, Austin C, Varma A, Pinyakorn S, Kroon E, Colby DJ, Chan P, Goh O, Pornpaisakul K, Intasan J, Luekasemsuk T, Robb ML, Chomchey N, Phanuphak N, Ananworanich J, Vasan S, Hsu D, SEARCH 010/RV254 study group. Impaired creatinine-based estimated glomerular filtration rate in Thai individuals switching to dolutegravir: illustrating the role of cystatin C testing to aid clinical decision making. AIDS Res Ther 2025, 22: 15. PMID: 39920714, DOI: 10.1186/s12981-025-00712-0.
• Optimal Magnitude of Blood Pressure Reduction and Hematoma Growth and Functional Outcomes in Intracerebral HemorrhageLi Q, Lv X, Morotti A, Qureshi A, Dowlatshahi D, Falcone G, Sheth K, Shoamanesh A, Murthy S, Viswanathan A, Goldstein J. Optimal Magnitude of Blood Pressure Reduction and Hematoma Growth and Functional Outcomes in Intracerebral Hemorrhage. Neurology 2025, 104: e213412. PMID: 39913881, PMCID: PMC11803522, DOI: 10.1212/wnl.0000000000213412.
• HIV, smoking, and the brain: a convergence of neurotoxicitiesOrlinick B, Farhadian S. HIV, smoking, and the brain: a convergence of neurotoxicities. AIDS Research And Therapy 2025, 22: 13. PMID: 39915881, PMCID: PMC11804093, DOI: 10.1186/s12981-025-00714-y.
• The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational studyZiai W, Woo D, Sansing L, Hanley D, Ostapkovich N, Triene K, Gilkerson L, Thompson R, Walborn N, Lane K, McBee N, Langefeld C, Howard T, Vagal A, Flaherty M, Consortium F. The REpeated ASSEssment of SurvivorS in intracerebral haemorrhage: protocol for a multicentre, prospective observational study. BMJ Open 2025, 15: e094322. PMID: 39915023, PMCID: PMC11800296, DOI: 10.1136/bmjopen-2024-094322.
• Voltage-gated sodium channels in excitable cells as drug targetsAlsaloum M, Dib-Hajj S, Page D, Ruben P, Krainer A, Waxman S. Voltage-gated sodium channels in excitable cells as drug targets. Nature Reviews Drug Discovery 2025, 1-21. PMID: 39901031, DOI: 10.1038/s41573-024-01108-x.
• Retrospective Visual and Quantitative Assessment of Burst Suppression With and Without Identical Bursts in Patients After Cardiac ArrestFong M, Pu K, Beekman R, Kim N, Nguyen C, Gilmore E, Hirsch L, Zaveri H. Retrospective Visual and Quantitative Assessment of Burst Suppression With and Without Identical Bursts in Patients After Cardiac Arrest. Neurocritical Care 2025, 1-11. PMID: 39900751, DOI: 10.1007/s12028-024-02208-7.
• Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid taperingYamamura R, Kinoshita M, Yasumizu Y, Yata T, Kihara K, Motooka D, Shiraishi N, Sugiyama Y, Beppu S, Murata H, Koizumi N, Sano I, Koda T, Okuno T, Mochizuki H. Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering. Frontiers In Immunology 2025, 16: 1508977. PMID: 39963140, PMCID: PMC11830620, DOI: 10.3389/fimmu.2025.1508977.
• Abstract 21: At least 1 in 4 Stroke Survivors do Not Achieve Adequate BP ControlForman R, Sharma R, de Havenon A, Williams J, Xin X, Kim C, Sheth K, viscoli C, Lu Y. Abstract 21: At least 1 in 4 Stroke Survivors do Not Achieve Adequate BP Control. Stroke 2025, 56: a21-a21. DOI: 10.1161/str.56.suppl_1.21.
• Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depressionRivier C, Szejko N, Renedo D, Clocchiatti-Tuozzo S, Huo S, de Havenon A, Zhao H, Gill T, Sheth K, Falcone G. Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression. Nature Communications 2025, 16: 1261. PMID: 39893209, PMCID: PMC11787333, DOI: 10.1038/s41467-024-54721-0.
• Abstract 108: APOE Epsilon 4 Carriers Derive Greater Benefit from Genetically Reduced Factor XI LevelsClocchiatti-Tuozzo S, Rivier C, Huo S, Hawkes M, Schwamm L, Ohno-Machado L, Sheth K, Gill T, Falcone G. Abstract 108: APOE Epsilon 4 Carriers Derive Greater Benefit from Genetically Reduced Factor XI Levels. Stroke 2025, 56: a108-a108. DOI: 10.1161/str.56.suppl_1.108.
• Abstract 141: Clinical Trial Emulation Leveraging Genetic Effects: A Proof-of-Concept Application to SPRINTClocchiatti-Tuozzo S, Rivier C, Huo S, Shoamanesh A, Kamel H, Murthy S, de Havenon A, Sansing L, Gill T, Sheth K, Falcone G. Abstract 141: Clinical Trial Emulation Leveraging Genetic Effects: A Proof-of-Concept Application to SPRINT. Stroke 2025, 56: a141-a141. DOI: 10.1161/str.56.suppl_1.141.
• Abstract 15: Integrated Genomic and Proteomic Drug Target Discovery for Ischemic StrokeHuo S, Clocchiatti-Tuozzo S, Magid-Bernstein J, Sharma R, RANGARAJU S, Sansing L, Sheth K, Rivier C, Falcone G. Abstract 15: Integrated Genomic and Proteomic Drug Target Discovery for Ischemic Stroke. Stroke 2025, 56: a15-a15. DOI: 10.1161/str.56.suppl_1.15.
• Abstract 44: Minimally Invasive Surgery is Associated with Improved Outcomes Compared to Open Craniotomy with Clot Evacuation after Spontaneous Intracerebral Hemorrhage in the AHA Get With The Guidelines RegistryMurthy S, Zhang C, Garton A, Mac Grory B, Shah S, Fonarow G, Schwamm L, Bhatt D, Smith E, Falcone G, Payabvash S, Ziai W, Knopman J, Matouk C, Mocco J, Kamel H, Sheth K. Abstract 44: Minimally Invasive Surgery is Associated with Improved Outcomes Compared to Open Craniotomy with Clot Evacuation after Spontaneous Intracerebral Hemorrhage in the AHA Get With The Guidelines Registry. Stroke 2025, 56: a44-a44. DOI: 10.1161/str.56.suppl_1.44.
• Abstract 49: Genomic Profiling and Risk of Intracerebral Hemorrhage in Patients with Atrial Fibrillation on ApixabanClocchiatti-Tuozzo S, Rivier C, Huo S, Gilmore E, Shoamanesh A, Kamel H, Murthy S, Ohno-Machado L, Sheth K, Gill T, Falcone G. Abstract 49: Genomic Profiling and Risk of Intracerebral Hemorrhage in Patients with Atrial Fibrillation on Apixaban. Stroke 2025, 56: a49-a49. DOI: 10.1161/str.56.suppl_1.49.
• Abstract 96: Integrated Genomic and Proteomic Profiling Support Cathepsin-B as a Drug Repurposing Target in Cerebral Small Vessel DiseaseRivier C, Huo S, Clocchiatti-Tuozzo S, Renedo D, Sharma R, Payabvash S, Sansing L, RANGARAJU S, Sheth K, Falcone G. Abstract 96: Integrated Genomic and Proteomic Profiling Support Cathepsin-B as a Drug Repurposing Target in Cerebral Small Vessel Disease. Stroke 2025, 56: a96-a96. DOI: 10.1161/str.56.suppl_1.96.
• Abstract DP21: Polygenic Resistance to Vascular Risk Factor Control in Stroke SurvivorsHuo S, Rivier C, Clocchiatti-Tuozzo S, Renedo D, Lopez V, Sunmonu N, Petersen N, de Havenon A, Sheth K, Falcone G. Abstract DP21: Polygenic Resistance to Vascular Risk Factor Control in Stroke Survivors. Stroke 2025, 56: adp21-adp21. DOI: 10.1161/str.56.suppl_1.dp21.
• Abstract TP191: Cerebrospinal Fluid Proinflammatory Cytokines are Associated with Poor Outcome following Hemorrhagic StrokeSorensen G, Grychowski L, Yan J, Herman A, He Z, Johnson C, Beatty H, Jayasundara S, Falcone G, Gilmore E, Matouk C, Sheth K, Kim J, Petersen N, Sansing L, Magid-Bernstein J. Abstract TP191: Cerebrospinal Fluid Proinflammatory Cytokines are Associated with Poor Outcome following Hemorrhagic Stroke. Stroke 2025, 56: atp191-atp191. DOI: 10.1161/str.56.suppl_1.tp191.
• Abstract TP305: Prevalence and Predictors of Post-Stroke Anxiety and DepressionMcNamara K, White M, Peyravi R, Zubair A, Driskell L, Fesharaki-Zadeh A, Leary M, Lopez V, Kampp M, Shah D, Forman R, Falcone G, Sheth K, Sansing L, Pittenger C, Sharma R. Abstract TP305: Prevalence and Predictors of Post-Stroke Anxiety and Depression. Stroke 2025, 56: atp305-atp305. DOI: 10.1161/str.56.suppl_1.tp305.
• Abstract WMP19: Mitigating Adverse Brain Health Outcomes Through Longitudinal Changes in Brain Care Score: A UK Biobank StudyKimball T, Marini S, Parodi L, Tack R, Prapiadou S, Senff J, Tan B, Rivier C, Kourkoulis C, Falcone G, Yechoor N, Rosand J, Singh S, Mayerhofer E, Anderson C. Abstract WMP19: Mitigating Adverse Brain Health Outcomes Through Longitudinal Changes in Brain Care Score: A UK Biobank Study. Stroke 2025, 56: awmp19-awmp19. DOI: 10.1161/str.56.suppl_1.wmp19.
• Abstract 117: Comparison of Three Computational Algorithms for Determining Personalized Blood Pressure Targets after ThrombectomyThinzar P, Jayasundara S, Vargas D, Stoehr K, Gilmore E, Kim J, Beekman R, Matouk C, Smielewski P, Miller E, Ortega-Gutierrez S, Petersen N. Abstract 117: Comparison of Three Computational Algorithms for Determining Personalized Blood Pressure Targets after Thrombectomy. Stroke 2025, 56: a117-a117. DOI: 10.1161/str.56.suppl_1.117.
• Abstract WMP77: Assessing Effects of Nimodipine-Associated Blood Pressure Reductions on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid HemorrhageJayasundara S, Choi R, Rapuano A, Chen Y, Top I, Olexa M, Maarek R, Yan J, Vargas D, Magid-Bernstein J, Amllay A, OKeefe L, Hebert R, Bahrassa F, Sheth K, Beekman R, Gilmore E, Matouk C, Kim J, Petersen N. Abstract WMP77: Assessing Effects of Nimodipine-Associated Blood Pressure Reductions on Cerebral Autoregulation and Cortical Activity in Aneurysmal Subarachnoid Hemorrhage. Stroke 2025, 56: awmp77-awmp77. DOI: 10.1161/str.56.suppl_1.wmp77.
• Abstract WMP92: Assessing Effects of Intra-Arterial Verapamil on Cerebral Hemodynamics and Autoregulation Following Aneurysmal Subarachnoid HemorrhageStoehr K, Jayasundara S, Vargas D, Thinzar P, Rapuano A, Maarek R, Beekman R, Magid-Bernstein J, OKeefe L, Matouk C, Hebert R, Gilmore E, Kim J, Petersen N. Abstract WMP92: Assessing Effects of Intra-Arterial Verapamil on Cerebral Hemodynamics and Autoregulation Following Aneurysmal Subarachnoid Hemorrhage. Stroke 2025, 56: awmp92-awmp92. DOI: 10.1161/str.56.suppl_1.wmp92.
• BPS2025 - Conformational transition of prestin—the electro-mechanical transducer in outer hair cells of the inner earZhang C, Mariadasse R, Beckstein O, Santos-Sacchi J, Navaratnam D. BPS2025 - Conformational transition of prestin—the electro-mechanical transducer in outer hair cells of the inner ear. Biophysical Journal 2025, 124: 315a. DOI: 10.1016/j.bpj.2024.11.1746.
• Abstract 102: Association Between Kidney Function and Severity of White Matter Hyperintensity: The Atherosclerosis Risk in Communities StudyLittig L, Krothapalli N, Wong K, Kim Y, Smith H, de Havenon A. Abstract 102: Association Between Kidney Function and Severity of White Matter Hyperintensity: The Atherosclerosis Risk in Communities Study. Stroke 2025, 56: a102-a102. DOI: 10.1161/str.56.suppl_1.102.
• Abstract 150: Racial and Ethnic Disparities in Post-stroke Quality of Life: A Post-Hoc Analysis of the SHINE TrialLittig L, Calvario E, Wong K, Krothapalli N, Kim Y, Smith H, de Havenon A. Abstract 150: Racial and Ethnic Disparities in Post-stroke Quality of Life: A Post-Hoc Analysis of the SHINE Trial. Stroke 2025, 56: a150-a150. DOI: 10.1161/str.56.suppl_1.150.
• Abstract 154: 10-Year Trend Analysis of Medicare Payment in Stroke Inpatient Hospital AdmissionWong K, Krothapalli N, Littig L, Champagne A, Majersik J, Reddy V, de Havenon A. Abstract 154: 10-Year Trend Analysis of Medicare Payment in Stroke Inpatient Hospital Admission. Stroke 2025, 56: a154-a154. DOI: 10.1161/str.56.suppl_1.154.
• Abstract 45: Time to Treatment in Intracerebral Hemorrhage Across the United StatesMelmed K, Lele A, Ayodele M, Goldstein J, LacKamp A, Dombrowski K, Alkhachroum A, Mainali S, de Havenon A, Krishnamohan P, Subramaniam T, Stretz C, Lee W, Kuohn L, Fong C, Houghton M, Campbell A, Song S, O'Phelan K, Sheth K, Venkatasubramanian C, Yaghi S, Mayer S, Diaz I, Frontera J. Abstract 45: Time to Treatment in Intracerebral Hemorrhage Across the United States. Stroke 2025, 56: a45-a45. DOI: 10.1161/str.56.suppl_1.45.
• Abstract DP53: Drivers of Disparities in Stroke Outcomes by Neighborhood Socioeconomic Status: A Causal Mediation AnalysisStulberg E, Miller R, Hartman N, de Havenon A, Lisabeth L. Abstract DP53: Drivers of Disparities in Stroke Outcomes by Neighborhood Socioeconomic Status: A Causal Mediation Analysis. Stroke 2025, 56: adp53-adp53. DOI: 10.1161/str.56.suppl_1.dp53.
• Abstract HUP1: Drivers of Disparities in Stroke Outcomes by Neighborhood Socioeconomic Status: A Causal Mediation AnalysisStulberg E, Miller R, Hartman N, de Havenon A, Lisabeth L. Abstract HUP1: Drivers of Disparities in Stroke Outcomes by Neighborhood Socioeconomic Status: A Causal Mediation Analysis. Stroke 2025, 56: ahup1-ahup1. DOI: 10.1161/str.56.suppl_1.hup1.
• Abstract TMP9: What Drives Early Recurrence in Intracranial Atherosclerosis: A Multicenter StudyYaghi S, Wu M, Shu L, Stipanovich A, Heldner M, Goldstein E, Kvernland A, Raz E, Hakim A, Radojewski P, Mordasini P, Antonenko K, Almiri W, de Havenon A, Prabhakaran S, Liebeskind D, Nguyen T, Furie K. Abstract TMP9: What Drives Early Recurrence in Intracranial Atherosclerosis: A Multicenter Study. Stroke 2025, 56: atmp9-atmp9. DOI: 10.1161/str.56.suppl_1.tmp9.
• Abstract WMP106: Stroke Risk and Urinary Albumin-to-Creatinine Ratio: A Post-Hoc Analysis of the ACCORD TrialKim Y, Krothapalli N, Littig L, de Havenon A. Abstract WMP106: Stroke Risk and Urinary Albumin-to-Creatinine Ratio: A Post-Hoc Analysis of the ACCORD Trial. Stroke 2025, 56: awmp106-awmp106. DOI: 10.1161/str.56.suppl_1.wmp106.
• Abstract WMP4: Intravenous Thrombolysis in Patients on Direct Oral Anticoagulants: Analysis of the Get With Guidelines Stroke RegistryYaghi S, Shu L, Mistry E, Adeoye O, Schwamm L, Messe S, Elkind M, Ghannam M, de Havenon A, Furie K, Xian Y, Streib C, Wangqin R, Henninger N, Saver J, Smith E. Abstract WMP4: Intravenous Thrombolysis in Patients on Direct Oral Anticoagulants: Analysis of the Get With Guidelines Stroke Registry. Stroke 2025, 56: awmp4-awmp4. DOI: 10.1161/str.56.suppl_1.wmp4.
• Abstract WP234: Education and Outcomes in Intracerebral Hemorrhage: A Post-Hoc Analysis of the ERICH StudyKrothapalli N, Wong K, Littig L, Kim Y, Smith H, Calvario E, Champagne A, Narula R, Sheth K, Sansing L, de Havenon A. Abstract WP234: Education and Outcomes in Intracerebral Hemorrhage: A Post-Hoc Analysis of the ERICH Study. Stroke 2025, 56: awp234-awp234. DOI: 10.1161/str.56.suppl_1.wp234.
• Abstract WP235: Insurance Status and Intracerebral Hemorrhage Outcomes: A Post-Hoc Analysis of the ERICH StudyKrothapalli N, Wong K, Littig L, Kim Y, Smith H, Calvario E, Champagne A, Narula R, Sheth K, Sansing L, de Havenon A. Abstract WP235: Insurance Status and Intracerebral Hemorrhage Outcomes: A Post-Hoc Analysis of the ERICH Study. Stroke 2025, 56: awp235-awp235. DOI: 10.1161/str.56.suppl_1.wp235.
• Abstract WP290: Cardiovascular and Stroke Outcomes in Bipolar Disorder: A Secondary Analysis of the SPRINT TrialSmith H, Krothapalli N, Littig L, de Havenon A. Abstract WP290: Cardiovascular and Stroke Outcomes in Bipolar Disorder: A Secondary Analysis of the SPRINT Trial. Stroke 2025, 56: awp290-awp290. DOI: 10.1161/str.56.suppl_1.wp290.
• Abstract DP17: Higher Pre-Admission Blood Pressure Is Associated with Lower Initial Infarct Volume after Acute Large Vessel OcclusionsGalecio-Castillo M, Shogren S, Begunova Y, Olexa M, Kalakoti P, Cruz-Criollo L, Petersen N, Ortega-Gutierrez S. Abstract DP17: Higher Pre-Admission Blood Pressure Is Associated with Lower Initial Infarct Volume after Acute Large Vessel Occlusions. Stroke 2025, 56: adp17-adp17. DOI: 10.1161/str.56.suppl_1.dp17.
• Abstract 42: Statin Use in Cervical Artery Dissection and Subsequent Ischemic StrokeLodhi O, Yaghi S, Shu L, Chung N, Guerrero C, Engelter S, Kaufmann J, Traenka C, Kam W, Zubair A, AlMajali M, Affan M. Abstract 42: Statin Use in Cervical Artery Dissection and Subsequent Ischemic Stroke. Stroke 2025, 56: a42-a42. DOI: 10.1161/str.56.suppl_1.42.
• Abstract DP45: Antithrombotic trends before and after publication of randomized clinical trials in cervical artery dissection: A secondary analysis of the STOP-CAD StudyPenckofer M, Shu L, Strelecky L, Yaghi S, Henninger N, Muppa J, Bakradze E, Heldner M, Katheryna A, Omran S, Seiffge D, Arnold M, Marialuisa Z, Zubair A, Marto J, Ghannam M, Engelter S, Traenka C, Mac Grory B, Kam W, Elnazeir M, Romoli M, Velez F, Siegler J. Abstract DP45: Antithrombotic trends before and after publication of randomized clinical trials in cervical artery dissection: A secondary analysis of the STOP-CAD Study. Stroke 2025, 56: adp45-adp45. DOI: 10.1161/str.56.suppl_1.dp45.
• Revised Process for ACNS Guidelines DevelopmentQuraishi I, Andrade E, Galloway G, Hyslop A, Selioutski O, Sinha S, Arnold S, Arya R, Bagić A, Drislane F, Gloss D, Hani A, Kobayashi E, Marashly A, Nuwer M, Park J, Sabau D, San-juan D, Shahid A, Skjei K, Tatum W, Vengrow M, Wusthoff C. Revised Process for ACNS Guidelines Development. Journal Of Clinical Neurophysiology 2025, 42: 95-100. PMID: 39883486, DOI: 10.1097/wnp.0000000000001133.
• Abstract 144: Mobile Stroke Unit Management and Outcomes in Undifferentiated Patients with Stroke-Like Symptoms in the Prehospital Setting: A Nationwide Cohort StudyMac Grory B, Sun J, Alhanti B, Lusk J, Li F, Adeoye O, Furie K, Hasan D, Messe S, Sheth K, Schwamm L, Smith E, Bhatt D, Fonarow G, Saver J, Xian Y, Grotta J. Abstract 144: Mobile Stroke Unit Management and Outcomes in Undifferentiated Patients with Stroke-Like Symptoms in the Prehospital Setting: A Nationwide Cohort Study. Stroke 2025, 56: a144-a144. DOI: 10.1161/str.56.suppl_1.144.
• Abstract 46: Rapid Implementation of Endovascular Thrombectomy Is Associated with Improved Health Equity in Stroke Outcomes: An Analysis of the Get With The Guidelines®-Stroke RegistryLusk J, Liu B, Obrien E, Hasan D, Fonarow G, Sheth K, Schwamm L, Xian Y, Albers G, Saver J, Li F, Mac Grory B. Abstract 46: Rapid Implementation of Endovascular Thrombectomy Is Associated with Improved Health Equity in Stroke Outcomes: An Analysis of the Get With The Guidelines®-Stroke Registry. Stroke 2025, 56: a46-a46. DOI: 10.1161/str.56.suppl_1.46.
• Abstract TMP48: Racial, Ethnic and Rural Disparities in Access to Acute Stroke Capabilities Persist even with TelestrokeZachrison K, Hsia R, Boggs K, Gao J, Messac L, Schwamm L, Reeves M, Fung V, Samuels-Kalow M, Camargo C. Abstract TMP48: Racial, Ethnic and Rural Disparities in Access to Acute Stroke Capabilities Persist even with Telestroke. Stroke 2025, 56: atmp48-atmp48. DOI: 10.1161/str.56.suppl_1.tmp48.
• Abstract WMP73: Evolution of Ischemic Stroke Etiology Diagnosis During Stroke HospitalizationEllsworth P, Lee H, Sansing L, Schwamm L, Thottempudi N, Sharma R. Abstract WMP73: Evolution of Ischemic Stroke Etiology Diagnosis During Stroke Hospitalization. Stroke 2025, 56: awmp73-awmp73. DOI: 10.1161/str.56.suppl_1.wmp73.
• Abstract WP135: Race-Ethnic Specific Hospital Arrival Time of Acute Ischemic Stroke by State in the U.S.Chen B, Sun J, Fonarow G, Alhanti B, Mac Grory B, Smith E, Schwamm L, Bhatt D, Saver J, Xian Y, Uchino K, Man S. Abstract WP135: Race-Ethnic Specific Hospital Arrival Time of Acute Ischemic Stroke by State in the U.S. Stroke 2025, 56: awp135-awp135. DOI: 10.1161/str.56.suppl_1.wp135.
• Abstract WP171: Antithrombotic Therapy for Secondary Stroke Prevention in Patients with Severe Chronic Kidney Disease and Atrial FibrillationJones E, Ayodele I, Obrien E, Laskowitz D, Fonarow G, Matsouaka R, Schwamm L, Smith E, Bhatt D, Peterson E, Xian Y. Abstract WP171: Antithrombotic Therapy for Secondary Stroke Prevention in Patients with Severe Chronic Kidney Disease and Atrial Fibrillation. Stroke 2025, 56: awp171-awp171. DOI: 10.1161/str.56.suppl_1.wp171.
• Abstract WP273: Selection of Antithrombotic Therapy in Patients with Atrial Fibrillation who Experience an Ischemic Stroke While on Anticoagulant TherapyWang D, Obrien E, Xian Y, Sherrod C, Chan P, Laskowitz D, Peterson E, Fonarow G, Schwamm L, Smith E, Bhatt D, Ayodele I, Matsouaka R. Abstract WP273: Selection of Antithrombotic Therapy in Patients with Atrial Fibrillation who Experience an Ischemic Stroke While on Anticoagulant Therapy. Stroke 2025, 56: awp273-awp273. DOI: 10.1161/str.56.suppl_1.wp273.
• Abstract WP4: Imaging-based Intravenous Thrombolysis for Patients ≥85 Years with Unknown Onset Stroke: EOS Individual Patient Data Meta-AnalysisKamogawa N, Miwa K, Toyoda K, Jensen M, Inoue M, Yoshimura S, Fukuda-Doi M, Ma H, Ringleb P, Wu O, Schwamm L, Warach S, Hacke W, Davis S, Donnan G, Gerloff C, Thomalla G, Koga M. Abstract WP4: Imaging-based Intravenous Thrombolysis for Patients ≥85 Years with Unknown Onset Stroke: EOS Individual Patient Data Meta-Analysis. Stroke 2025, 56: awp4-awp4. DOI: 10.1161/str.56.suppl_1.wp4.
• Abstract WP97: Derivation and Validation of the Get with the Guidelines®-Stroke Endovascular Thrombectomy Risk ScoresLusk J, Brown S, Hassan A, Albers G, Fonarow G, Schwamm L, Messe S, Smith E, Hasan D, Bhatt D, Saver J, Mac Grory B. Abstract WP97: Derivation and Validation of the Get with the Guidelines®-Stroke Endovascular Thrombectomy Risk Scores. Stroke 2025, 56: awp97-awp97. DOI: 10.1161/str.56.suppl_1.wp97.
• Abstract 118: Long Term Outcomes in the CHARM Trial Evaluating Intravenous Glyburide for the Treatment of Large Hemispheric InfarctionSheth K, Molyneaux B, Saver J, Albers G, Campbell B, Steiner T, Toyoda K, Wintermark M, Nogueira R, Simard J, Jacobson S, Cordonnier C, Hinson H, Kimberly W. Abstract 118: Long Term Outcomes in the CHARM Trial Evaluating Intravenous Glyburide for the Treatment of Large Hemispheric Infarction. Stroke 2025, 56: a118-a118. DOI: 10.1161/str.56.suppl_1.118.
• Abstract 5: Glyburide for Large Hemispheric Infarcts ≤125 mL: a Meta-Analysis of Individual Patient Data from the GAMES-RP and CHARM TrialsKimberly W, Hinson H, Albers G, Saver J, Campbell B, Molyneaux B, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Nogueira R, Simard J, Jacobson S, Sheth K. Abstract 5: Glyburide for Large Hemispheric Infarcts ≤125 mL: a Meta-Analysis of Individual Patient Data from the GAMES-RP and CHARM Trials. Stroke 2025, 56: a5-a5. DOI: 10.1161/str.56.suppl_1.5.
• Abstract 56: Intravenous Glyburide in Large Core, Endovascular-Treated Stroke Patients: An Analysis of the CHARM TrialSheth K, Albers G, Saver J, Campbell B, Molyneaux B, Hinson H, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Nogueira R, Simard J, Jacobson S, Kimberly W. Abstract 56: Intravenous Glyburide in Large Core, Endovascular-Treated Stroke Patients: An Analysis of the CHARM Trial. Stroke 2025, 56: a56-a56. DOI: 10.1161/str.56.suppl_1.56.
• Abstract DP35: Enhanced Stroke Detection with Multi-directional Diffusion Weighted Low-field Magnetic Resonance ImagingSorby-Adams A, Pinter N, Kirsch J, Jaikumar V, Goldstein J, Nelson O, Bacchi S, Guo J, Pitts J, Lee V, Muir K, Nimjee S, Rosen M, Iglesias J, Sheth K, Kimberly W. Abstract DP35: Enhanced Stroke Detection with Multi-directional Diffusion Weighted Low-field Magnetic Resonance Imaging. Stroke 2025, 56: adp35-adp35. DOI: 10.1161/str.56.suppl_1.dp35.
• Safety and efficacy of nipocalimab in adults with generalised myasthenia gravis (Vivacity-MG3): a phase 3, randomised, double-blind, placebo-controlled studyAntozzi C, Vu T, Ramchandren S, Nowak R, Farmakidis C, Bril V, De Bleecker J, Yang H, Minks E, Park J, Grudniak M, Smilowski M, Sevilla T, Hoffmann S, Sivakumar K, Suzuki Y, Youssef E, Sanga P, Karcher K, Zhu Y, Sheehan J, Sun H, Group T. Safety and efficacy of nipocalimab in adults with generalised myasthenia gravis (Vivacity-MG3): a phase 3, randomised, double-blind, placebo-controlled study. The Lancet Neurology 2025, 24: 105-116. PMID: 39862879, DOI: 10.1016/s1474-4422(24)00498-8.
• Abstract TP139: Coordinating Stroke and Sleep Care with Field Staff and Champions: Difference-Makers in a Quality Improvement Program Addressing Sleep Apnea in Stroke PatientsRattray N, Miech E, Bravata D, Story K, Myers L, KOO B, Burrone L, Sexson A, Taylor S, Perkins A, Daggy J, Sico J. Abstract TP139: Coordinating Stroke and Sleep Care with Field Staff and Champions: Difference-Makers in a Quality Improvement Program Addressing Sleep Apnea in Stroke Patients. Stroke 2025, 56: atp139-atp139. DOI: 10.1161/str.56.suppl_1.tp139.
• Abstract WP164: Creating an Acute Sleep Medicine Service for Veterans Hospitalized with an Acute Ischemic Stroke or Transient Ischemic Attack – A Comparative Case Study from the Addressing Sleep Apnea Post-Stroke/TIA Hybrid Type I Stepped-Wedge Cluster Randomized TrialSico J, Rattray N, Burrone L, Sexson A, Miech E, Story K, KOO B, Taylor S, Myers L, Perkins A, Daggy J, Bravata D. Abstract WP164: Creating an Acute Sleep Medicine Service for Veterans Hospitalized with an Acute Ischemic Stroke or Transient Ischemic Attack – A Comparative Case Study from the Addressing Sleep Apnea Post-Stroke/TIA Hybrid Type I Stepped-Wedge Cluster Randomized Trial. Stroke 2025, 56: awp164-awp164. DOI: 10.1161/str.56.suppl_1.wp164.
• Abstract WMP51: Addressing Sleep Apnea Post-Stroke and Transient Ischemic Attack (ASAP) Stepped-Wedge Cluster-Randomized Trial: Effectiveness of a Quality Improvement Intervention to Increase Sleep Apnea Diagnostic TestingBravata D, Perkins A, Myers L, Daggy J, Sexson A, Taylor S, Burrone L, KOO B, Miech E, Rattray N, Story K, Waddell K, Ding Q, Jason S. Abstract WMP51: Addressing Sleep Apnea Post-Stroke and Transient Ischemic Attack (ASAP) Stepped-Wedge Cluster-Randomized Trial: Effectiveness of a Quality Improvement Intervention to Increase Sleep Apnea Diagnostic Testing. Stroke 2025, 56: awmp51-awmp51. DOI: 10.1161/str.56.suppl_1.wmp51.
• Association of Causative Pathogens With Acute Kidney Injury in Adult Patients With Community-Onset SepsisPant P, Chihara S, Krishnamoorthy V, Treggiari M, Messina J, Privratsky J, Raghunathan K, Ohnuma T. Association of Causative Pathogens With Acute Kidney Injury in Adult Patients With Community-Onset Sepsis. Critical Care Explorations 2025, 7: e1219. PMID: 39937578, PMCID: PMC11826047, DOI: 10.1097/cce.0000000000001219.
• Abstract 54: Stroke Incidence by Race in a Large, Biracial Population Over Time: 2020 UpdateStanton R, Robinson D, Ding L, Menzies L, Wechsler P, LaPorta J, Aziz Y, Slavin S, Wright S, Nobel L, Walsh K, DeLosRiosLaRosa F, Ferioli S, Stamm B, Haverbusch M, Mackey J, Mistry E, Demel S, Coleman E, Jasne A, Star M, Martini S, Adeoye O, Flaherty M, Khatri P, Woo D, Broderick J, Kissela B, Kleindorfer D. Abstract 54: Stroke Incidence by Race in a Large, Biracial Population Over Time: 2020 Update. Stroke 2025, 56: a54-a54. DOI: 10.1161/str.56.suppl_1.54.
• Abstract DP24: Trends in Stroke Incidence Over Time by Sex in the Greater Cincinnati Northern Kentucky Stroke Study (GCNKSS)Madsen T, Demel S, Ding L, Adeoye O, Broderick J, Flaherty M, ferioli S, Haverbusch M, Jasne A, Khatri P, DeLosRiosLaRosa F, Mackey J, Martini S, Mistry E, Coleman E, Aziz Y, Wechsler P, Menzies L, Wright S, Nobel L, LaPorta J, Robinson D, Slavin S, Star M, Stamm B, Stanton R, Walsh K, Woo D, Kissela B, Kleindorfer D. Abstract DP24: Trends in Stroke Incidence Over Time by Sex in the Greater Cincinnati Northern Kentucky Stroke Study (GCNKSS). Stroke 2025, 56: adp24-adp24. DOI: 10.1161/str.56.suppl_1.dp24.
• Abstract TP272: Transthoracic Echocardiographic Findings in Cryptogenic stroke: Prevalence and Comparisons to other Subtypes of Ischemic StrokeNabavizadeh P, Stanton R, Sucharew H, Merkler A, Sharma R, La Rosa F, Mackey J, Ferioli S, Mistry E, Demel S, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Haverbusch M, Woo D, Robinson D, Khatrip P, Kissela B, Kleindorfer D. Abstract TP272: Transthoracic Echocardiographic Findings in Cryptogenic stroke: Prevalence and Comparisons to other Subtypes of Ischemic Stroke. Stroke 2025, 56: atp272-atp272. DOI: 10.1161/str.56.suppl_1.tp272.
• Abstract TP75: Trends in Stroke Symptom Onset to Emergency Department Arrival Time in the Greater Cincinnati and Northern Kentucky Stroke StudyRoyan R, Stamm B, Sucharew H, Robinson D, Haverbusch M, Ferioli S, Stanton R, Aziz Y, LaPorta J, Woo D, Wechsler P, Menzies L, Wright S, Nobel L, Slavin S, Walsh K, DeLosRiosLaRosa F, Mackey J, Mistry E, Demel S, Coleman E, Jasne A, Star M, Martini S, Adeoye O, Madsen T, Kissela B, Kleindorfer D. Abstract TP75: Trends in Stroke Symptom Onset to Emergency Department Arrival Time in the Greater Cincinnati and Northern Kentucky Stroke Study. Stroke 2025, 56: atp75-atp75. DOI: 10.1161/str.56.suppl_1.tp75.
• Abstract WP146: Racial Differences in Percutaneous Endoscopic Gastrostomy (PEG) Placement in Post-Stroke DysphagiaKrekeler B, Ding L, Haverbusch M, Ferioli S, David R, Stanton R, Aziz Y, Laporta J, Wechsler P, Menzies L, Wright S, Nobel L, Slavin S, Walsh K, DeLosRiosLaRosa F, Stamm B, Mackey J, Mistry E, Demel S, Coleman E, Jasne A, Star M, Martini S, Adeoye O, Flaherty M, Woo D, Kleindorfer D, Kissela B. Abstract WP146: Racial Differences in Percutaneous Endoscopic Gastrostomy (PEG) Placement in Post-Stroke Dysphagia. Stroke 2025, 56: awp146-awp146. DOI: 10.1161/str.56.suppl_1.wp146.
• Abstract WP333: Population-based Study of Stroke Recurrence in Overweight or Obese Patients: Considerations for Future Prevention TrialsYahnke I, Sucharew H, Broderick J, Robinson D, Kleindorfer D, Ferioli S, Mackey J, Woo D, DeLosRiosLaRosa F, Demel S, Mistry E, Coleman E, Jasne A, Slavin S, Walsh K, Star M, Stanton R, Ljungberg L, Kamel H, Haverbusch M, Kissela B. Abstract WP333: Population-based Study of Stroke Recurrence in Overweight or Obese Patients: Considerations for Future Prevention Trials. Stroke 2025, 56: awp333-awp333. DOI: 10.1161/str.56.suppl_1.wp333.
• Abstract WP98: Temporal Trends and Predictors of Door-in-Door-out Times for Interhospital Stroke Transfers in the Greater Cincinnati Northern Kentucky Stroke StudyStamm B, Royan R, Ding L, Robinson D, Haverbusch M, Ferioli S, Stanton R, Aziz Y, LaPorta J, Woo D, Wechsler P, Menzies L, Wright S, Nobel L, Slavin S, Walsh K, DeLosRiosLaRosa F, Mackey J, Mistry E, Demel S, Coleman E, Jasne A, Star M, Martini S, Adeoye O, Flaherty M, Khatri P, Madsen T, Broderick J, Kissela B, Kleindorfer D. Abstract WP98: Temporal Trends and Predictors of Door-in-Door-out Times for Interhospital Stroke Transfers in the Greater Cincinnati Northern Kentucky Stroke Study. Stroke 2025, 56: awp98-awp98. DOI: 10.1161/str.56.suppl_1.wp98.
• Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional studyMarek K, Russell D, Concha-Marambio L, Choi S, Jennings D, Brumm M, Coffey C, Brown E, Seibyl J, Stern M, Soto C, Siderowf A. Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study. EBioMedicine 2025, 112: 105567. PMID: 39893720, PMCID: PMC11835612, DOI: 10.1016/j.ebiom.2025.105567.
• Polygenic Susceptibility to Diabetes and Poor Glycemic Control in Stroke SurvivorsDemarais Z, Conlon C, Rivier C, Clocchiatti-Tuozzo S, Renedo D, Torres-Lopez V, Sheth K, Meeker D, Zhao H, Ohno-Machado L, Acosta J, Huo S, Falcone G. Polygenic Susceptibility to Diabetes and Poor Glycemic Control in Stroke Survivors. Neurology 2025, 104: e210276. PMID: 39889253, DOI: 10.1212/wnl.0000000000210276.
• Mild Malformation of Cortical Development With Oligodendroglial Hyperplasia and EpilepsyZhan Y, Chen S, Jin Z, Zhou J, Zhang Y, Hou Q, Wang Y, Zheng G, Zheng Y. Mild Malformation of Cortical Development With Oligodendroglial Hyperplasia and Epilepsy. Neurology Genetics 2025, 11: e200240. PMID: 39902276, PMCID: PMC11790282, DOI: 10.1212/nxg.0000000000200240.
• Pearls & Oy-sters: Isolated Acquired Amusia in a Patient With Right Temporal Stroke.Dibbs M, Moeller J. Pearls & Oy-sters: Isolated Acquired Amusia in a Patient With Right Temporal Stroke. Neurology 2025, 104: e213410. PMID: 39889265, DOI: 10.1212/wnl.0000000000213410.