The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque
Weinberg-Wolf H, Fagan NA, Anderson GM, Tringides M, Dal Monte O, Chang SWC. The effects of 5-hydroxytryptophan on attention and central serotonin neurochemistry in the rhesus macaque. Neuropsychopharmacology 2018, 43: 1589-1598. PMID: 29463909, PMCID: PMC5983545, DOI: 10.1038/s41386-017-0003-7.Peer-Reviewed Original ResearchConceptsSerotonergic interventionsSalient facial featuresCentral serotonergic functioningCisternal cerebrospinal fluidBaseline attentionCognitive operationsSerotonin's roleIndividual differencesBi-directional effectsAutonomic arousalSaline sessionsImmediate serotonin precursorEngaged individualsBehavioral impairmentsFacial featuresSerotonergic functioningStimulus animalsRole of serotoninPupil sizeAnxietyPsychiatric disordersSerotonin neurochemistrySerotoninergic functionSerotonin effectsCSF concentrations