2020
Genetics of structural and functional brain changes in autism spectrum disorder
Hashem S, Nisar S, Bhat A, Yadav S, Azeem M, Bagga P, Fakhro K, Reddy R, Frenneaux M, Haris M. Genetics of structural and functional brain changes in autism spectrum disorder. Translational Psychiatry 2020, 10: 229. PMID: 32661244, PMCID: PMC7359361, DOI: 10.1038/s41398-020-00921-3.Peer-Reviewed Original ResearchConceptsASD patientsAutism spectrum disorderFunctional brain changesSpecific single nucleotide polymorphismsClinical managementIsolated disorderBrain changesSpectrum disorderTherapeutic interventionsFunctional changesNoninvasive imagingDisordersSingle nucleotide polymorphismsGenetic disordersPatientsRisk genesDevelopmental disordersSocial impairmentNeuropsychiatryASD diagnosisCommunicative behavior
2019
Association of genes with phenotype in autism spectrum disorder
Nisar S, Hashem S, Bhat A, Syed N, Yadav S, Azeem M, Uddin S, Bagga P, Reddy R, Haris M. Association of genes with phenotype in autism spectrum disorder. Aging 2019, 11: 10742-10770. PMID: 31744938, PMCID: PMC6914398, DOI: 10.18632/aging.102473.Peer-Reviewed Original ResearchConceptsASD risk genesRisk genesNovel candidate genesAssociation of genesGene transcriptionGenetic pathwaysNeuronal activity modulationCandidate genesGenesGenetic variantsPathophysiology of ASDPathwayHeterogeneous neurodevelopmental disorderRegulation processesActivity modulationSynaptic plasticityNeurodevelopmental disordersTranscriptionIdentificationGeneticsPhenotypeRolePlasticityAutism spectrum disorderField of neuroscience