Yale Scientists Breach Brain Barriers to Attack Tumors
The brain is a sort of fortress, equipped with barriers designed to keep out dangerous pathogens. But protection comes at a cost: These barriers interfere with the immune system when faced with dire threats such glioblastoma, a deadly brain tumor for which there are few effective treatments.
Enzyme mutations may protect against vascular thrombosis and stroke
Yale researchers have identified the mechanism behind a molecular variation that reduces risk of stroke in children with sickle cell anemia. The molecular variation was recently identified but not understood due to a limited grasp of the gene’s role in hemostasis — the stopping of bleeding. These new findings open a path for the development of novel drugs that may prevent stroke, particularly in children with sickle cell anemia who are at risk of this devastating complication.
Alzheimer’s missing link found: Is a promising target for new drugs
Yale School of Medicine researchers have discovered a protein that is the missing link in the complicated chain of events that lead to Alzheimer’s disease, they report in the Sept. 4 issue of the journal Neuron. Researchers also found that blocking the protein with an existing drug can restore memory in mice with brain damage that mimics the disease.
Major Gift Will Support an Innovative Brain Research Collaboration
The Swiss-based NOMIS Foundation is making a large five-year award for research into what makes the human brain unique. The research will be a collaboration between the laboratories of James P. Noonan, PhD, associate professor of genetics and of neuroscience at Yale School of Medicine, and Franck Polleux, PhD, professor of neuroscience at Columbia University and a member of that school’s Zuckerman Institute. Their combined mission is to understand the brain and mind.
Major Gift Will Endow a Program Devoted to a Fuller Understanding of How the Human Brain Works
The Thomas Kingsley Lawrence ’19 Program in Brain Research will take a multifaceted approach to understanding the higher-order functionality of the human brain and related areas. It is hoped that with the knowledge gained, novel prevention strategies, diagnostics, and therapeutics to reduce the incidence, prevalence, and recurrence of psychiatric disorders will be possible.
Brain Scans, Aided by Artificial Intelligence, Reveal as Much About Us as Our DNA, Evan Morris Says.
“Brain scans, aided by artificial intelligence, reveal as much about us as our DNA,” Evan Morris recently wrote in an op-ed in Wired magazine. “Grappling with their ethical implications is vital to scientific integrity.”
Save the Dates: Kavli Institute for Neuroscience Two-day Symposium: "Cell Biology of Parkinson's Disease Genes" on April 28-29
The Kavli Institute for Neuroscience is organizing a two-day symposium, "Cell Biology of Parkinson’s Disease Genes," April 28-29, 2020. Registration required by the February 25, 2020.
Mammals’ Enhanced Capacity to See Emerges Early in Development
All vertebrates possess a primitive network in which the retina sends signals directly to the superior colliculus, an area of the brain that processes visual stimuli. In a more recently evolved pathway, signals from the retina are received in the thalamus and are relayed to the cortex, the brain’s seat of higher-order thinking.
U.S. Surgeon General’s Advisory: Marijuana Use and the Developing Brain
This advisory is intended to raise awareness of the known and potential harms to developing brains, posed by the increasing availability of highly potent marijuana in multiple, concentrated forms. These harms are costly to individuals and to our society, impacting mental health and educational achievement and raising the risks of addiction and misuse of other substances.Source: Surgeon General’s Advisory
Dr. Barbara Banz and DrivSim Lab Faculty Present Research at 42nd Annual RSA Scientific Meeting
Abstracts Published in the journal Alcoholism: Clinical and Experimental Research, Volume 43, Issue S1; June 2019 Pages: 54A (Abstract 110); 135A (Abstract 433 and 434); 195A (Abstract 675) Abstract 110: RELATING RECENT BINGE-DRINKING AND FREQUENT DRINKING SYMPTOMS TO NEURAL RESPONSES OF SECONDARY TASK ENGAGEMENT IN DRIVING SIMULATION IN A YOUNG ADULT POPULATION Conclusions: These data show significant relationships for recent binge drinking and frequent drinking symptoms with attentional processing which may translate to limitations in performing secondary task engagement during driving simulation. Our brain-based data offer insight into a contextual setting where attentional faculties are critical for safety. These data hold important implications for distracted driving and crash risks among sober young drivers with a history of heavy drinking.