Strategies to accelerate diagnosis and treatment of rare cardiovascular diseases
The current landscape for patients with rare cardiovascular disease has shifted. Using genome sequencing Yale physician-scientists have begun to elucidate the pathophysiology of genetic disorders and develop treatment guidelines and recommendations.
Study illuminates tiny RNA’s role in heart disease, obesity
A tiny RNA molecule plays a big role in the development of two diseases affecting billions of people worldwide: heart disease and obesity. Yale researchers have found that by disrupting this microRNA in key tissues, they can reduce plaque buildup in arteries while avoiding unintended effects.
Yale lab finding may protect the heart during ischemia
Research from three Yale laboratories — in the fields of immunobiology, chemistry, and cardiology — could lead to new drugs to reduce complications during cardiac surgery or heart attacks. If they pan out in human trials, the drugs would limit the detrimental impact of ischemia—restriction of blood flow—thereby cutting the degree of damage to the heart. The research appeared in the June online issue of Circulation.
Good News, Bad News for Older Survivors of Acute MI
A new 25-year study reveals that mortality after an acute myocardial infarction (AMI) and repeat events are coming down for all older Americans. But it also highlights the need for more work, especially efforts to root out healthcare inequities.Source: Medscape
Next-generation LAA closure device lowers risk for in-hospital major adverse events
Patients who underwent left atrial appendage closure with a next-generation device were significantly less likely to experience in-hospital major adverse events, including pericardial effusion, compared with an earlier-generation device.Source: Cardiology Today
Different Factors Drive Heart Attack Risk in Young Women vs Young Men
An analysis of data from more than 2000 matched pairs suggests the impact of multiple risk factors, including diabetes, depression, and hypertension, on the risk of acute myocardial infarction were greater among young women than their male counterparts.Source: Practical Cardiology