Study illuminates tiny RNA’s role in heart disease, obesity
A tiny RNA molecule plays a big role in the development of two diseases affecting billions of people worldwide: heart disease and obesity. Yale researchers have found that by disrupting this microRNA in key tissues, they can reduce plaque buildup in arteries while avoiding unintended effects.
Yale lab finding may protect the heart during ischemia
Research from three Yale laboratories — in the fields of immunobiology, chemistry, and cardiology — could lead to new drugs to reduce complications during cardiac surgery or heart attacks. If they pan out in human trials, the drugs would limit the detrimental impact of ischemia—restriction of blood flow—thereby cutting the degree of damage to the heart. The research appeared in the June online issue of Circulation.
Krumholz Receives the American Heart Association's Clinical Research Prize
Krumholz was recognized “for his work as a founding leader in the field of outcomes research. His work has led to improvements in the quality of care and outcomes for millions of patients nationwide and beyond,” said American Heart Association President Robert A. Harrington, MD, FAHA.
Yale Offers New Medication for Fatal Disease
Yale Medicine physicians were the first in Connecticut to offer a new medication for hereditary transthyretin-mediated amyloidosis (hATTR), a life-threatening genetic mutation that causes transport proteins called transthyretin to cluster together and deposit amyloids in the peripheral nerves, heart, kidney, and gastrointestinal tract.