Raise Your Voice About Your Metastatic Breast Cancer
Breast cancer is a common diagnosis for women of all races. But there are differences along racial lines when it comes to early detection, treatment, and survival rates. The disease is deadliest for non-Hispanic Black women. They’re more likely than women of other races or ethnicities to get diagnosed with metastatic breast cancer (cancer that has spread to other parts of the body), and they have higher odds of having triple-negative breast cancer (TNBC). TNBC is a hard-to-treat form of the disease that spreads fast. Genes and biology play a role in breast cancer. But racial and ethnic minorities face barriers to health care. People of color tend to have less access to health insurance and get fewer referrals to specialty medical care. There’s also evidence that some doctors spend less time with Black people, says Andrea Silber, MD, a breast oncologist and assistant clinical director for health equity and diversity at Yale Cancer Center and Smilow Cancer Hospital.Source: WebMD
A Strange Rash Had Doctors Stumped. Was It an Insect Bite?
The 73-year-old man looked up at the clear summer sky — the morning was nearly gone. He had finished mowing the main part of his lawn and was trimming the edges near the shrubbery with the weed wacker. He wanted to finish before the sun and heat made the work too hard. Suddenly he felt a sharp sting on the lower part of his shin. He glanced down at his bare leg. Nothing there. He still had the hedges to trim, so he kept working. He quickly finished the needed pruning, then moved on to the inside tasks he had planned.Source: The New York Times Magazine
How do hair follicles grow? A Yale-led study untangles the science
An outstanding question in dermatology that researchers have studied for decades is: How do hair follicles emerge from a sea of seemingly uniform skin cells during embryonic development? New research findings from a Yale-led team offer answers to that question, which may lead to strategies for regenerating lost hair follicles in adults.
Yale experts treat severe, disfiguring sarcoidosis with novel therapy
An all-Yale team of researchers successfully treated a patient with disfiguring sarcoidosis, a disease that can affect multiple organs, with a drug approved for rheumatoid arthritis. Successful treatment of two other patients with similarly severe disease suggests an effective treatment for an incurable, sometimes life-threatening illness is within reach.
Two Yale School of Medicine MD-PhD Students Receive Prestigious Soros Fellowship for New Americans
Jonathan Marques and Diana Yanez, both currently in the School of Medicine’s (YSM) MD-PhD program, have been selected as 2018 Soros Fellows. Marquez and Yanez are among 30 recipients of the Paul & Daisy Soros Fellowships for New Americans. Fellows, all of whom are children of immigrants to the Unites States, Deferred Action for Childhood Arrival recipients, green card holders, or naturalized citizens, were selected from a pool of 1,766 applicants for their potential to make significant contributions to United States society, culture, or their academic fields, and for their commitment to the United States’ fundamental principles and ideals.
Skin Health: New Insights from a Rare Disease
Skin is the largest organ in the human body, yet we often take for granted all of the wonderful things that it does to keep us healthy. That’s not the case for people who suffer from a group of rare, scale-forming skin disorders known as ichthyoses.Source: NIH Directors Blog
Yale Cancer Center researchers win Sokoloff Family-Melanoma Research Alliance team science award
A new approach to understanding why T-cells are often too weak to fight and destroy tumor cells has earned Yale Cancer Center researchers team science award from the Sokoloff Family-Melanoma Research Alliance (MRA).
Yale-led study zeroes in on mutation linked to zits
Little is known about the genetic causes of pimples and other forms of acne that plague most teenagers. In a new study, a team of Yale researchers identified a genetic mutation responsible for the defects that give rise to mild and severe acne. Their finding might point to new targets for acne treatment.
Yale study identifies ‘major player’ in skin cancer genes
A multidisciplinary team at Yale, led by Yale Cancer Center members, has defined a subgroup of genetic mutations that are present in a significant number of melanoma skin cancer cases. Their findings shed light on an important mutation in this deadly disease, and may lead to more targeted anti-cancer therapies.
Mutation Mystery: A Clinician Seeks Answers to Improve Skin Cancer Treatment for Women
Dr. Christine Ko has launched a study to see if a mutated gene can serve as a biological marker to predict the growth rate and recurrence of squamous cell carcinoma, a type of tumor of the thin outer layer of skin that affects about 700,000 Americans each year.
A tiny RNA with a big role in melanoma
A Yale-led study has identified a key mechanism in the regulation of gene expression that promotes the proliferation of melanoma cells. The finding opens a possible avenue for development of treatments that target this mechanism. The study appears online Feb. 18 in the journal eLife.
Review Sheds Light on Understudied Truncal Acne Vulgaris
A recent review written by co-author and Yale Associate Professor of Dermatology Christopher Bunick MD, PhD and published in in "American Journal of Clinical Dermatology" characterizes truncal acne vulgaris, a psychosocially burdensome yet misunderstood skin disorder, and summarizes evaluation and treatment options.
Yale expert familiar with procedure used on First Lady Jill Biden’s skin cancer
In light of First Lady Jill Biden's diagnosis and subsequent treatment for basal cell cancer, Yale dermatologic surgeons David Leffell, MD explains the symptoms of the condition and expands on the Moh's surgery technique used to remove the First Lady's cancer.Source: WTNH News8
Psoriasis on the Knees and Elbows: What It Looks Like, How to Treat It
She’s been mortified by these flares since childhood. “As a kid, I’d go to day camp wearing jeans and long-sleeved shirts — and I never, ever wore a bathing suit,” she recalls. The knees and elbows are the most common location for psoriasis flare-ups. “Those are the textbook cases,” says Elisabeth Richard, MD, an assistant professor of dermatology at the Johns Hopkins University School of Medicine in Baltimore. Psoriasis on these body parts tends to have a distinctive appearance: “You’ll usually see a well-circumscribed plaque, bigger than a centimeter, with thickened skin and overlying white scales,” Dr. Richard explains. Plaques may appear red or salmon pink on white skin and purple or brown on Black or brown skin. Psoriasis most often appears on the front of the knees and the elbows, known as extensor surfaces, says Jeffrey Cohen, MD, an assistant professor of dermatology and director of the psoriasis treatment program at Yale Medical School in New Haven, Connecticut.Source: Everyday Health
Chemical Hair Straighteners and Cancer: What You Need to Know
If you are a woman who has used chemical hair straightening products, a new report issued by the National Institutes of Health may have caused you concern. The NIH released findings that link chemical hair straightening products to uterine cancer. These results might cause you to question your own use of hair care products and wonder what you should do next. For now, experts suggest that there is no need to panic. More research is needed before we know for sure which ingredients may be problematic. But still, women of color and others who use these products are (reasonably) worried. We talked to both medical and hair care experts to get some answers to ease your mind.Source: Health & Wellness
Microneedling Can Help Surgical Scars Fade, Especially If Done Early
A technique called microneedling may help surgical scars heal more attractively — especially if it's done within a couple of months of surgery, a small study suggests. Researchers found that for 25 patients, microneedling improved the long-term appearance of scars after various types of surgery — based on both patient and doctor ratings. But the sooner it was done, the better. Patients who underwent their first microneedling session within six or seven weeks of surgery had the best results. That, the researchers said, goes against the "conventional wisdom," which holds that microneedling should be delayed until scars are about a year old.Source: U.S. News
Biosimilar-to-Biosimilar Switches Deemed Safe and Effective, Systematic Review Reveals
Switching from one biosimilar medication to another is safe and effective, a new systematic review indicates, even though this clinical practice is not governed by current health authority regulations or guidance. "No reduction in effectiveness or increase in adverse events was detected in biosimilar-to-biosimilar switching studies conducted to date," the review's authors note in their study, published online July 26 in BioDrugs. "The possibility of multiple switches between biosimilars of the same reference biologic is already a reality, and these types of switches are expected to become more common in the future. …although it is not covered by current health authority regulations or guidance," add the authors, led by Hillel P. Cohen, PhD, executive director of scientific affairs at Sandoz, a division of Novartis.Source: Medscape