Darin Dolezal, MD/PhD
Research & Publications
Biography
News
Research Summary
I am involved in numerous research projects that focus on 1.) better understanding how tumor cells circulate/ metastasize, and 2.) utilizing molecular approaches to develop minimally invasive cancer diagnostics. My goal is to have a career in academic pathology that combines clinical service in cytopathology with applied and basic research in molecular cytopathology.
Extensive Research Description
The goal of one ongoing research project, which is supported by an intradepartmental Chair’s Challenge grant, is to detect driver and resistance mutations in pleural fluid-derived circulating tumor DNA from patients with lung adenocarcinoma. The aim of this project is to use an error-suppressed multiplex deep sequencing platform, originally designed to detect low abundance tumor-specific mutations in plasma, to detect mutations with high sensitivity in the supernatants of malignant pleural effusions.
Coauthors
Selected Publications
- Breast Carcinoma With Tubulopapillary Features Has a Distinct Immunophenotypic and Molecular Signature: A Report of Two Tumors and Literature Review.Carrasco-Tenezaca F, Moreira-Dinzey J, Manrai P, Bearse M, Burela S, Podany P, Singh K, Pareja F, Zheng J, Muscato N, Liang Y, Zhan H, Krishnamurti U, Dolezal D, Wang J, Harigopal M. Breast Carcinoma With Tubulopapillary Features Has a Distinct Immunophenotypic and Molecular Signature: A Report of Two Tumors and Literature Review. International Journal Of Surgical Pathology 2023, 10668969231209780. PMID: 37908113, DOI: 10.1177/10668969231209780.
- S2209 Pancreatic Insulinoma: A Hidden ChallengeMathialagan K, Dolezal D, Nagar A. S2209 Pancreatic Insulinoma: A Hidden Challenge. The American Journal Of Gastroenterology 2023, 118: s1585-s1585. DOI: 10.14309/01.ajg.0000958476.17153.c1.
- Fine Needle Aspiration Diagnosis of Malignant Neoplasms Secondarily Involving the Thyroid: An Institutional ExperienceDolezal D, Zuo T, Adeniran A, Raad R, Cai G. Fine Needle Aspiration Diagnosis of Malignant Neoplasms Secondarily Involving the Thyroid: An Institutional Experience. Journal Of The American Society Of Cytopathology 2018, 7: s23. DOI: 10.1016/j.jasc.2018.06.058.