Grants and contracts awarded to Yale School of Medicine, November/December 2005

Federal

• Robert Alpern, NIH, General Clinical Research Center (Robert Sherwin, M.D., Director), 5 years, $23,993,166
• Daniel Goldstein, NIH, Role of Innate Immunity in Transplantation Tolerance, 4 years, $1,308,000
• Karl Insogna, Dept. of Agriculture (US), Dietary Protein Affects Intestinal Calcium Absorption: Consequences and Mechanism, 3 years, $475,000
• Michael Koelle, NIH, G Protein Signaling in the C. elegansNervous System, 5 years, $1,823,147
• David McCormick, NIH, Calcium Signaling & Prefrontal Deficits in Schizophrenia, 3 years, $6,187,258
• Sherry McKee, NIH, Do Pharmacological Treatments for Smoking Cessation Reduce Alcohol Drinking?, 4 years, $1,178,552
• Hongyu Zhao, NIH, Statistical Methods to Map Genes for Complex Traits, 4 years, $1,238,739

Non-Federal

• Janet Brandsma, Go Therapeutics, Inc., Particulate Delivery Vehicle for Ad-Based Vaccination Against Cottontail Rabbit Papillomavirus (CRPV) Infection in Rabbits, 10 months, $19,234
• David Cheng, Pfizer, Inc., Y-003-04 Study-Increasing FDG-PET Specificity with Krebs Cycle Flux Using Spectroscopy, 2 years, $588,301
• Jin-Young Choi, Arthritis Foundation, Toll-like Receptor Stimulation in CNS Lupus, 2 years, $150,000
• Lauren Cohn, Millennium Pharmaceuticals Inc., Direct Measurement of AHR in CRTH2-Deficient Mice, 1 year, $16,350
• Cynthia Epperson, National Alliance for Research on Schizophrenia and Depression, Serotonin, Neurosteroids and GABA Contributions to SSRI Treatment Response in PMDD: A 1H-MRS Study, 2 years, $100,000
• Durland Fish, New York Medical College, Genotypic Variation and B. burgdorferi Pathogenesis, 11 months, $42,189
• Judith Ford, University of California–Irvine, Function BIRN (Bioinformatics Research Network), 1 year, $235,000
• Liana Fraenkel, Arthritis Foundation, Improving Informed Choice for Patients Considering TJA, 1 year, $100,000
• Joel Gelernter, University of Connecticut Health Center, Genetic Versus Phenotype Markers of Relapse Risk, 5 years, $46,649
• Cary Gross, Common Sense Media, Media Evidence Assessment Project, 1 year, $10,000
• Handan Gunduz-Bruce, National Alliance for Research on Schizophrenia and Depression, GABA-Glutamate Interactions and Psychosis, 2 years, $60,000
• Keith Hawkins, Alzheimer’s Association, Neuropsychological Norms for Older African-Americans, 3 years, $239,992
• Steven Hebert and John Geibel, Amgen, Inc., CaSR Modulations, 2 years, amount confidential
• Yingqun Huang, Fannie E. Rippel Foundation, Use of a Novel siRNA Delivery System to Restore Chemosensitivity to Epithelial Ovarian Cancer Cells, 2 years, $150,000
• Judith Lichtman, Fannie E. Rippel Foundation, Determinant of Disparities in the Care and Outcomes for Young Women with Acute Myocardial Infarction, 1 year, $150,000
• Xiaomei Ma, Myeloproliferative Disorders Foundation, Epidemiology of Chronic Myeloproliferative Disorders, 1 year, $128,500
• John Macmicking, Searle Scholar Program, p47 GTPases: Decoding the Language of Immune Recognition for Phagosomal Pathogens, 3 years, $240,000
• Robert Malison, Hartford Hospital, Cocaine-Induced Place Preference Using Virtual Reality, 2 years, $74,589
• Graeme Mason, Dana Foundation, Quantitative MR Imaging and Spectroscopy in Alcoholism: GABA and Glutamate Impact of Genetic Vulnerability to Alcoholism, 3 years, $100,000
• Sarah Paterson, National Alliance for Autism Research, Brain Morphometry in Newborns at Risk for Autism: An MRI Study, 2 years, $118,360
• Jill Reiter, Breast Cancer Alliance, Inc., Quantitative Analysis of EGFR Variants in Breast Cancer, 2 years, $125,000
• Jennifer Ruger, Open Society Institute, Health Governance Project, 6 months, $49,611
• Albert Sinusas, Bristol-Myers Squibb Company, Noninvasive Imaging of Matrix Metalloproteinase in Chronic Rat Models of Myocardial Ischemic Injury: Implications of Early Prediction of LV Remodeling, 1 year, $108,788
• Jane Taylor, Tourette Syndrome Association, Inc., Instrumental Habit Behavior as an Animal Model of Tourette’s Syndrome: Investigation of the Role of Striatal and Frontal Cortical Signaling Pathways, 1 year, $60,825
• Edward Uchio, American Geriatrics Society, Aging Effects on the VHL Tumor Suppressor Pathway in the Development of Renal Carcinoma, 2 years, $75,000
• Agnes Vignery, Boehringer Ingelheim Pharmaceuticals, Inc., Identification and Functional Characterization of New Molecular Targets to Treat Osteoporosis and Rheumatoid Arthritis, 2 years, $180,000
• Joanne Weidhaas, Breast Cancer Alliance, Inc., Defining the Best Treatment Options in BRCA1-mediated Breast Cancer Using a C. elegans Model of Radiosensitivity, 2 years, $125,000
• Kevin White, University of California–San Diego, Molecular Basis of Cell Tolerance to O2 Deprivation, 7 months, $10,014
• Scott Woods, Research Foundation for Mental Hygiene, D-Serine Treatment of Schizophrenia, 1 year, $193,150
• Kimberly Yonkers, State of CT Dept. of Public Health, Provider Education for Perinatal Depression, 6 months, $125,000