Adjunct Faculty
Adjunct faculty typically have an academic or research appointment at another institution and contribute or collaborate with one or more School of Medicine faculty members or programs.
Adjunct rank detailsJohn Seibyl, MD
Professor AdjunctAbout
Research
Publications
2026
Joint EANM/SNMMI recommendations on the use of Tau PET imaging in Alzheimer's disease
Brendel M, Kuo P, Brumberg J, Doré V, Drzezga A, Garibotto V, Leuzy A, Mathoux G, Meyer P, Moscoso A, Ossenkoppele R, Pascoal T, Smith R, Seibyl J, van de Giessen E, Van Weehaeghe D, Vermeiren M, Villemagne V, Esfahani S, Barthel H, Committee T, Brendel M, Cecchin D, Fernandez P, Guedj E, Tolboom N, Traub-Weidinger T, Van Weehaeghe D, Verger A, Yakushev I. Joint EANM/SNMMI recommendations on the use of Tau PET imaging in Alzheimer's disease. The EANM Journal 2026, 3: 100214. DOI: 10.1016/j.eanmj.2026.100214.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsFive‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Gonzalez‐Latapi P, Gochanour C, Choi S, Cho H, Caspell‐Garcia C, Coffey C, Brumm M, Lafontant D, Xiao Y, Tropea T, Seibyl J, Tanner C, Venuto C, Kieburtz K, Chahine L, Poston K, Siderowf A, Marek K, Simuni T, Initiative T. Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease. Annals Of Clinical And Translational Neurology 2026 PMID: 41808287, DOI: 10.1002/acn3.70323.Peer-Reviewed Original ResearchToward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale
Fan Z, Searle G, Rizzo G, Albani J, Cella P, Comley R, Klein G, Passamonti L, Salinas C, Schwarz A, Iaccarino L, Tamagnan G, Eberling J, Marek K, Seibyl J, Gunn R, Marek K, Tanner C, Simuni T, Siderowf A, Galasko D, Chahine L, Coffey C, Merchant K, Poston K, Dobkin R, Foroud T, Mollenhauer B, Weintraub D, Brown E, Kieburtz K, Frasier M, Sherer T, Chowdhury S, Alcalay R, Videnovic A, Tosun‐Turgut D, Poewe W, Bressman S, Hammer J, James R, Riley E, Seibyl J, Shaw L, Standaert D, Mantri S, Dahodwala N, Schwarzschild M, Marras C, Fernandez H, Shoulson I, Rowbotham H, Casalin P, Trenkwalder C, Sherer T, Chowdhury S, Frasier M, Eberling J, Kopil K, O'Grady A, Kuhl M, Kirsch L, Willson T, Adler C, Alcalay R, Amara A, Barone P, Bloem B, Bressman S, Brockmann K, Brüggemann N, Chahine L, Chou K, Dahodwala N, Espay A, Factor S, Fernandez H, Fullard M, Galasko D, Hauser R, Hogarth P, Hu S, Hu M, Isaacson S, Klein C, Krueger R, Lew M, Mari Z, Marras C, Martí M, McFarland N, Mestre T, Mollenhauer B, Moukheiber E, Noyce A, Okubadejo N, O'Shea S, Pahwa R, Pavese N, Poewe W, Postuma R, Riboldi G, Ruffrage L, Martinez J, Russell D, Saint‐Hilaire M, Santos N, Schlett47 W, Schneider R, Shill H, Shprecher D, Simuni T, Standaert D, Stefanis L, Tai Y, Tanner C, Tarakad A, PhD34 E, Videnovic A, Ainscough S, Blair C, Botting E, Chung I, Clark K, Croitoru I, DeLano K, Egner I, Esha F, Eshel M, Ferrari F, Foster V, Garrido A, Grümmer M, Herrera B, Hilt E, Huntzinger C, James R, Kausar F, Koros C, Krasowski60 Y, Le D, Liu Y, Marques T, Santana H, Mosovsky S, Mule J, Ng P, O'Brien L, Ogunleye A, Ojo O, Onyinanya O, Pennente L, Perrotti R, Pileggi M, Ramachandran A, Raymond D, Razzaque J, Reddie S, Ribb K, Rizer K, Rodriguez J, Roman S, Sanchez C, Simonet C, Singh A, Sittig E, Sommerfeld B, Stovall A, Stubbeman B, Valenzuela A, Wandell C, Willeke D, Williams K, Wubuli D. Toward Harmonizing Quantification of Dopamine Neuron Imaging Biomarkers in Parkinson's Disease: The Centamine Scale. Annals Of Neurology 2026, 99: 949-963. PMID: 41556298, PMCID: PMC13011789, DOI: 10.1002/ana.78116.Peer-Reviewed Original Research
2025
Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study
Marek K, Russell D, Concha-Marambio L, Choi S, Jennings D, Brumm M, Coffey C, Brown E, Seibyl J, Stern M, Soto C, Siderowf A. Evidence for alpha-synuclein aggregation in older individuals with hyposmia: a cross-sectional study. EBioMedicine 2025, 112: 105567. PMID: 39893720, PMCID: PMC11835612, DOI: 10.1016/j.ebiom.2025.105567.Peer-Reviewed Original Research
2024
Combining cerebrospinal fluid and PI‐2620 tau‐PET for biomarker‐based stratification of Alzheimer's disease and 4R‐tauopathies
Dilcher R, Wall S, Groß M, Katzdobler S, Wagemann O, Palleis C, Weidinger E, Fietzek U, Bernhardt A, Kurz C, Ferschmann C, Scheifele M, Zaganjori M, Gnörich J, Bürger K, Janowitz D, Rauchmann B, Stöcklein S, Bartenstein P, Villemagne V, Seibyl J, Sabri O, Barthel H, Perneczky R, Schöberl F, Zwergal A, Höglinger G, Levin J, Franzmeier N, Brendel M. Combining cerebrospinal fluid and PI‐2620 tau‐PET for biomarker‐based stratification of Alzheimer's disease and 4R‐tauopathies. Alzheimer's & Dementia 2024, 20: 6896-6909. PMID: 39263969, PMCID: PMC11485081, DOI: 10.1002/alz.14185.Peer-Reviewed Original ResearchImproved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [18F]PI-2620
Bischof G, Brendel M, Barthel H, Theis H, Barbe M, Bartenstein P, Claasen J, Danek A, Höglinger G, Levin J, Marek K, Neumaier B, Palleis C, Patt M, Rullmann M, Saur D, Schroeter M, Seibyl J, Song M, Stephens A, Sabri O, Drzezga A, van Eimeren T, Tauopathies F. Improved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [18F]PI-2620. Journal Of Nuclear Medicine 2024, 65: jnumed.123.265930. PMID: 38575191, PMCID: PMC11149601, DOI: 10.2967/jnumed.123.265930.Peer-Reviewed Original ResearchTau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies
Ferschmann C, Messerschmidt K, Gnörich J, Barthel H, Marek K, Palleis C, Katzdobler S, Stockbauer A, Fietzek U, Finze A, Biechele G, Rumpf J, Saur D, Schroeter M, Rullmann M, Beyer L, Eckenweber F, Wall S, Schildan A, Patt M, Stephens A, Classen J, Bartenstein P, Seibyl J, Franzmeier N, Levin J, Höglinger G, Sabri O, Brendel M, Scheifele M. Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies. European Journal Of Nuclear Medicine And Molecular Imaging 2024, 51: 1909-1922. PMID: 38366196, PMCID: PMC11139736, DOI: 10.1007/s00259-024-06637-6.Peer-Reviewed Original ResearchA biological definition of neuronal α-synuclein disease: towards an integrated staging system for research
Simuni T, Chahine L, Poston K, Brumm M, Buracchio T, Campbell M, Chowdhury S, Coffey C, Concha-Marambio L, Dam T, DiBiaso P, Foroud T, Frasier M, Gochanour C, Jennings D, Kieburtz K, Kopil C, Merchant K, Mollenhauer B, Montine T, Nudelman K, Pagano G, Seibyl J, Sherer T, Singleton A, Stephenson D, Stern M, Soto C, Tanner C, Tolosa E, Weintraub D, Xiao Y, Siderowf A, Dunn B, Marek K. A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research. The Lancet Neurology 2024, 23: 178-190. PMID: 38267190, DOI: 10.1016/s1474-4422(23)00405-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2023
Dopamine Transporter Availability in Early Parkinson's Disease is Dependent on Sunlight Exposure
Booij J, Tellier S, Seibyl J, Vriend C. Dopamine Transporter Availability in Early Parkinson's Disease is Dependent on Sunlight Exposure. Movement Disorders 2023, 38: 2131-2135. PMID: 37670567, DOI: 10.1002/mds.29597.Peer-Reviewed Original ResearchNeurotheranostics: The Next Frontier for Health Span
Losee M, Seibyl J, Kuo P. Neurotheranostics: The Next Frontier for Health Span. Journal Of Nuclear Medicine Technology 2023, 51: jnmt.123.265502. PMID: 37586855, DOI: 10.2967/jnmt.123.265502.Peer-Reviewed Original Research