Hyojin Park
Associate Research ScientistCards
About
Research
Publications
2025
Restoring compromised blood-retina-barrier integrity with Netrin-1 overexpression
Furtado J, Zapadka T, Park H, Boyé K, Demb J, Eichmann A. Restoring compromised blood-retina-barrier integrity with Netrin-1 overexpression. Cellular And Molecular Life Sciences 2025, 82: 389. PMID: 41196411, PMCID: PMC12592616, DOI: 10.1007/s00018-025-05903-6.Peer-Reviewed Original ResearchPIEZO1 Overexpression in Hereditary Hemorrhagic Telangiectasia Arteriovenous Malformations
Park H, Lee S, Furtado J, Robinson M, Antaya R, Oh S, Hong Y, Schwartz M, Young L, Eichmann A. PIEZO1 Overexpression in Hereditary Hemorrhagic Telangiectasia Arteriovenous Malformations. Circulation 2025, 152: 599-615. PMID: 40665909, PMCID: PMC12270330, DOI: 10.1161/circulationaha.124.073630.Peer-Reviewed Original Research
2024
Interplay between Netrin-1 and Norrin controls arteriovenous zonation of blood–retina barrier integrity
Furtado J, Geraldo L, Leser F, Bartkowiak B, Poulet M, Park H, Robinson M, Pibouin-Fragner L, Eichmann A, Boyé K. Interplay between Netrin-1 and Norrin controls arteriovenous zonation of blood–retina barrier integrity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2408674121. PMID: 39693351, PMCID: PMC11670198, DOI: 10.1073/pnas.2408674121.Peer-Reviewed Original Research
2023
Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice
Lee S, Schleer H, Park H, Jang E, Boyer M, Tao B, Gamez-Mendez A, Singh A, Folta-Stogniew E, Zhang X, Qin L, Xiao X, Xu L, Zhang J, Hu X, Pashos E, Tellides G, Shaul P, Lee W, Fernandez-Hernando C, Eichmann A, Sessa W. Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice. Nature Cardiovascular Research 2023, 2: 438-448. PMID: 39196046, PMCID: PMC11358031, DOI: 10.1038/s44161-023-00266-2.Commentaries, Editorials and Letters
2022
Traffic Patterns of the Migrating Endothelium: How Force Transmission Regulates Vascular Malformation and Functional Shunting During Angiogenic Remodelling
Edgar LT, Park H, Crawshaw JR, Osborne JM, Eichmann A, Bernabeu MO. Traffic Patterns of the Migrating Endothelium: How Force Transmission Regulates Vascular Malformation and Functional Shunting During Angiogenic Remodelling. Frontiers In Cell And Developmental Biology 2022, 10: 840066. PMID: 35663401, PMCID: PMC9160721, DOI: 10.3389/fcell.2022.840066.Peer-Reviewed Original Research
2021
Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation
Zarkada G, Howard JP, Xiao X, Park H, Bizou M, Leclerc S, Künzel SE, Boisseau B, Li J, Cagnone G, Joyal JS, Andelfinger G, Eichmann A, Dubrac A. Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation. Developmental Cell 2021, 56: 2237-2251.e6. PMID: 34273276, PMCID: PMC9951594, DOI: 10.1016/j.devcel.2021.06.021.Peer-Reviewed Original ResearchDefective Flow-Migration Coupling Causes Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia
Park H, Furtado J, Poulet M, Chung M, Yun S, Lee S, Sessa WC, Franco CA, Schwartz MA, Eichmann A. Defective Flow-Migration Coupling Causes Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation 2021, 144: 805-822. PMID: 34182767, PMCID: PMC8429266, DOI: 10.1161/circulationaha.120.053047.Peer-Reviewed Original Research
2019
MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells.
Kim H, Ko Y, Park H, Zhang H, Jeong Y, Kim Y, Noh M, Park S, Kim YM, Kwon YG. MicroRNA-148a/b-3p regulates angiogenesis by targeting neuropilin-1 in endothelial cells. Exp Mol Med 2019, 51: 1-11. PMID: 31723119, DOI: 10.1038/s12276-019-0344-x.Peer-Reviewed Original Research
2017
Integrative analysis of DNA methylation and mRNA expression during differentiation of umbilical cord blood derived mononuclear cells to endothelial cells.
Jeong Y, Jun Y, Kim J, Park H, Choi KS, Zhang H, Park JA, Kwon JY, Kim YM, Lee S, Kwon YG. Integrative analysis of DNA methylation and mRNA expression during differentiation of umbilical cord blood derived mononuclear cells to endothelial cells. Gene 2017, 635: 48-60. PMID: 28887159, DOI: 10.1016/j.gene.2017.09.006.Peer-Reviewed Original ResearchSac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation.
Zhang H, Park JH, Maharjan S, Park JA, Choi KS, Park H, Jeong Y, Ahn JH, Kim IH, Lee JC, Cho JH, Lee IK, Lee CH, Hwang IK, Kim YM, Suh YG, Won MH, Kwon YG. Sac-1004, a vascular leakage blocker, reduces cerebral ischemia-reperfusion injury by suppressing blood-brain barrier disruption and inflammation. J Neuroinflammation 2017, 14: 122. PMID: 28645333, DOI: 10.1186/s12974-017-0897-3.Peer-Reviewed Original Research
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