Herta Chao, MD, PhD
Professor of Internal Medicine (Medical Oncology)DownloadHi-Res Photo
Cards
Appointments
Medical Oncology
Primary
Additional Titles
Deputy Director at the VA Comprehensive Cancer Center, Section of Hematology/Oncology, VA Connecticut Healthcare System
Contact Info
Appointments
Medical Oncology
Primary
Additional Titles
Deputy Director at the VA Comprehensive Cancer Center, Section of Hematology/Oncology, VA Connecticut Healthcare System
Contact Info
Appointments
Medical Oncology
Primary
Additional Titles
Deputy Director at the VA Comprehensive Cancer Center, Section of Hematology/Oncology, VA Connecticut Healthcare System
Contact Info
About
Titles
Professor of Internal Medicine (Medical Oncology)
Positions outside Yale
Deputy Director at the VA Comprehensive Cancer Center, Section of Hematology/Oncology, VA Connecticut Healthcare System
Appointments
Medical Oncology
ProfessorPrimary
Other Departments & Organizations
- Developmental Therapeutics
- Internal Medicine
- Medical Oncology
- MR Center
- Yale Cancer Center
- Yale Ventures
Education & Training
- Combined Residency
- Yale University, School of Medicine (2003)
- Postdoctoral Research Fellow
- Dana-Farber Cancer Institute (1999)
- Pediatric Intern
- University of Freiburg (1996)
- PhD
- Max Planck Institut, Neuroscience (1995)
- MD
- University of Goettingen, School of Medicine (1994)
Board Certifications
Hematology (Internal Medicine)
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2016
Medical Oncology
- Certification Organization
- AB of Internal Medicine
- Latest Certification Date
- 2016
- Original Certification Date
- 2006
Pediatrics
- Certification Organization
- AB of Pediatrics
- Original Certification Date
- 2004
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Latest Certification Date
- 2013
- Original Certification Date
- 2003
Research
Overview
Medical Research Interests
Clinical Trial; Lung Neoplasms; Medical Oncology; Prostatic Neoplasms
ORCID
0000-0002-4827-6757
Research at a Glance
Yale Co-Authors
Frequent collaborators of Herta Chao's published research.
Publications Timeline
A big-picture view of Herta Chao's research output by year.
Chiang-Shan Ray Li, MD, PhD
Michal Rose, MD
Shefali Chaudhary
Jaime Ide, PhD
Barbara Ehrlich, PhD
Cary Gross, MD
17Publications
523Citations
Publications
2023
Age-related reduction in trait anxiety: Behavioral and neural evidence of automaticity in negative facial emotion processing
Chaudhary S, Zhang S, Zhornitsky S, Chen Y, Chao H, Li C. Age-related reduction in trait anxiety: Behavioral and neural evidence of automaticity in negative facial emotion processing. NeuroImage 2023, 276: 120207. PMID: 37263454, PMCID: PMC10330646, DOI: 10.1016/j.neuroimage.2023.120207.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsFaster reaction timesNegative emotionsAge-related declineEmotional stimuliTrait anxietyAge-related reductionReaction timeEmotion regulation literatureSalient emotional stimuliPositive emotional stimuliFacial emotion processingPrefrontal cortical responsesRostral anterior cingulate cortexWhole-brain regressionAnterior cingulate activityDefault mode networkAnterior cingulate cortexEmotion regulationNeural evidenceEmotion processingDorsolateral PFCStimulus registrationDiminished anxietyPsychophysiological interactionEmotional circuitsDoes ADT Influence the Risk of Suicidal Ideation among US Veteran Prostate Cancer Patients Pre-Exposed to PTSD?
Brahmbhatt S, Chao H, Verma S, Gupta S. Does ADT Influence the Risk of Suicidal Ideation among US Veteran Prostate Cancer Patients Pre-Exposed to PTSD? Cancers 2023, 15: 2739. PMID: 37345076, PMCID: PMC10216772, DOI: 10.3390/cancers15102739.Peer-Reviewed Original ResearchAltmetricThe effects of age on the severity of problem drinking: Mediating effects of positive alcohol expectancy and neural correlates
Chaudhary S, Chen Y, Zhornitsky S, Le T, Zhang S, Chao H, Dominguez J, Li C. The effects of age on the severity of problem drinking: Mediating effects of positive alcohol expectancy and neural correlates. Addiction Biology 2023, 28: e13278. PMID: 37252876, DOI: 10.1111/adb.13278.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPositive alcohol expectanciesAlcohol Use Disorders Identification TestAlcohol expectanciesAlcohol use disorderNeural correlatesCue responsesPath analysisProblem drinkingAlcohol misuseEffect of ageAUDIT scoresRostral anterior cingulate cortexWhole-brain regressionAlcohol cue exposureMiddle occipital cortexModerate alcohol use disorderAlcohol Expectancy QuestionnaireAnterior cingulate cortexAlcohol use severityBilateral rostral anterior cingulate cortexPsychological mechanismsBilateral parahippocampal gyrusCue exposureNeural processesSeverity of problems
2022
Hypothalamic Functional Connectivity and Apathy in People with Alzheimer’s Disease and Cognitively Normal Healthy Controls
Chaudhary S, Zhornitsky S, Chao H, van Dyck C, Li C. Hypothalamic Functional Connectivity and Apathy in People with Alzheimer’s Disease and Cognitively Normal Healthy Controls. Journal Of Alzheimer's Disease 2022, 90: 1615-1628. PMID: 36314209, PMCID: PMC10064487, DOI: 10.3233/jad-220708.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMiddle temporal gyrusMild cognitive impairmentMotivation circuitsFunctional connectivityPath analysisWhole-brain regressionPCu/PCCState functional connectivityTotal scoreTemporal gyrusNeural markersCingulate cortexMemory dysfunctionRSFCHealthy controlsCognitive statusCognitive impairmentAlzheimer's diseaseApathyPrecuneusMemoryRsFCsDepressionScale total scoreCognitive subscores
2021
Improving hematology/oncology clinical research recruitment via universal prescreening: The VA Connecticut (VACT) Cancer Center experience.
Xiang J, Roy A, Summers C, Delvy M, O'Donovan J, Christensen J, Perry L, Connery D, Rose M, Chao H. Improving hematology/oncology clinical research recruitment via universal prescreening: The VA Connecticut (VACT) Cancer Center experience. Journal Of Clinical Oncology 2021, 39: 79-79. DOI: 10.1200/jco.2020.39.28_suppl.79.Peer-Reviewed Original ResearchCitationsConceptsLung cancer patientsCancer CenterClinical research recruitmentStudy enrollmentCancer patientsClinical trialsPotential eligibilityEligibility criteriaNew lung cancer patientsResearch enrollmentPotential study patientsCancer Center experienceTherapeutic clinical trialsNumber of patientsDiagnosis of cancerResearch recruitmentEligible patientsMalignancy workupPrimary oncologistStudy patientsChart reviewClinic visitsGenitourinary cancersPatient demographicsCenter experience
2018
Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers
Zhornitsky S, Ide J, Wang W, Chao H, Zhang S, Hu S, Krystal J, Li C. Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers. Brain Connectivity 2018, 8: 487-502. PMID: 30198312, PMCID: PMC6207153, DOI: 10.1089/brain.2018.0633.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAlcohol Use Disorders Identification TestResting-state functional connectivityThalamic connectivityCaudate connectivityFrontal associationThalamic dysfunctionCaudate headProblem drinkingWhole-brain linear regressionAE scoreSubcortical structuresFunctional connectivityBilateral caudate headRight caudate headDisorders Identification TestSex differencesThalamic subdivisionsThalamic subregionsParietal associationAlcohol misuseThalamusWhite matter tractographyAUDIT scoresNondependent drinkersAlcohol expectancies
2017
Concurrent Care and Aggressive End-of-Life Lung Cancer Care
Presley C, Han L, O'leary J, Chao H, Shamas T, Kerin A, Rose M, Gross C. Concurrent Care and Aggressive End-of-Life Lung Cancer Care. Journal Of Thoracic Oncology 2017, 12: s1545. DOI: 10.1016/j.jtho.2017.06.058.Peer-Reviewed Original ResearchCitations
2013
Changes in cerebral morphometry and amplitude of low-frequency fluctuations of BOLD signals during healthy aging: correlation with inhibitory control
Hu S, Chao H, Zhang S, Ide JS, Li CS. Changes in cerebral morphometry and amplitude of low-frequency fluctuations of BOLD signals during healthy aging: correlation with inhibitory control. Brain Structure And Function 2013, 219: 983-994. PMID: 23553547, PMCID: PMC3760988, DOI: 10.1007/s00429-013-0548-0.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsDorsal lateral prefrontal cortexInferior parietal lobuleSupplementary motor areaFrontal regionsInhibitory controlCingulate cortexStop-signal reaction timeBilateral dorsal lateral prefrontal cortexGM volumeCognitive performance decreasesRight inferior parietal lobuleLow-frequency fluctuationsLateral prefrontal cortexSignal reaction timePosterior cingulate cortexAnterior cingulate cortexBlood oxygenation level-dependent (BOLD) signalLevel-dependent signalFamily-wise errorGray matter volumeRecent alcohol useCognitive challengesParietal lobuleSpontaneous neural activityVoxel-based morphometry
2012
Timeliness of care and stage at diagnosis of non-small cell lung cancer (NSCLC) with the implementation of a cancer care coordination program (CCCP) at a VA medical center.
Alsamarai S, Chao H, Yao X, Deng Y, Rose M. Timeliness of care and stage at diagnosis of non-small cell lung cancer (NSCLC) with the implementation of a cancer care coordination program (CCCP) at a VA medical center. Journal Of Clinical Oncology 2012, 30: 6033-6033. DOI: 10.1200/jco.2012.30.15_suppl.6033.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerTimeliness of careLung cancerEarly-stage lung cancerVeterans Affairs Connecticut Healthcare SystemPercent of patientsInitiation of therapyRetrospective cohort analysisCare coordination programCancer-related symptomsInitiation of treatmentCell lung cancerPrimary care providersStage lung cancerVA Medical CenterAbnormal imagingNSCLC careNSCLC patientsInitial imagingPatient satisfactionMean intervalMedical CenterCohort analysisAbnormal imagesCare providersThe effects of age on cerebral activations: internally versus externally driven processes
Hu S, Chao H, Winkler AD, Li CS. The effects of age on cerebral activations: internally versus externally driven processes. Frontiers In Aging Neuroscience 2012, 4: 4. PMID: 22536185, PMCID: PMC3334814, DOI: 10.3389/fnagi.2012.00004.Peer-Reviewed Original ResearchCitationsAltmetricConceptsFunctional magnetic resonance imagingCerebral activationRegional brain activationAge-related decreaseCognitive processesPrepotent responsesPsychological constructsCognitive functioningSignal taskBrain activationGo trialsFMRI dataGo signalSE trialsEffect of ageImaging literatureYoung adultsStop signalHealthy adultsInfluence of ageSeeming inconsistencyAdultsMagnetic resonance imagingYears of ageFunctioning
Academic Achievements & Community Involvement
honor VISN1 Clinical Service Line Award, Medicine Service Line
Regional AwardDepartment of Veterans AffairsDetails10/02/2017United Stateshonor David S. Fischer, MD award for outstanding teaching & mentoring of fellows in Medical Oncology
Yale School of Medicine AwardYale School of Medicine and Yale Comprehensive Cancer CenterDetails06/16/2014United Stateshonor AACR Career Development
National AwardAmerican Association for Cancer ResearchDetails04/24/2006United Stateshonor Research Fellowship of the “Deutsche Forschungsgemeinschaft”
International AwardGerman Research AssociationDetails09/02/1998, 09/02/1997, 09/02/1996Germanyhonor Doctoral thesis "magna cum laude"
International AwardUniversity of Goettingen and Max Planck InstitutDetails01/30/1995Germany
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