Alyssa Ann Grimshaw, MBA, MLIS, MPH
Research & Education Librarian - ClinicalCards
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Research & Education Librarian - Clinical
Biography
Alyssa Grimshaw is a clinical research and education librarian at the Cushing/Whitney Medical Library.
She earned a post-master's certificate as an interprofessional informationist at Simmons University School of Library and Information Sciences. As an information expert, she collaborates on evidence synthesis and meta-research projects. Her research interests include reproducibility, reporting, and housing impacts on public health.
Alyssa provides in-depth reference, information, research and consultation services for clinical professionals and users in the health sciences community, including literature searches in support of systematic reviews, research, grants, clinical practice, animal use, teaching, and publishing.
For more information about me, please visit please page.
Departments & Organizations
Education & Training
- MPH
- Dartmouth , Public Health (2024)
- MBA
- Southern New Hampshire University, Healthcare Management (2022)
- MLIS
- Drexel University, Library & Information Sciences (2017)
Research
Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0003-3985-0056
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Craig Gunderson, MD, SFHM
James Farrell
Jan Philipp Bewersdorf, MD, FACP
Maximilian Stahl, MD
Alla Vash-Margita, MD, FACOG
Jaime A. Cavallo, MD, MPHS
Systematic Reviews as Topic
Publications
2025
Effect of Diabetes on Clinical Outcomes in Patients with Peripheral Arterial Disease undergoing Lower Extremity Revascularization: A Systematic Review and Meta-Analysis
Edjimbi J, Shah N, Kwaah P, Grimshaw A, Regan C, Nagpal S, Attaran R, Chaar C, Romain G, Smolderen K, Mena-Hurtado C. Effect of Diabetes on Clinical Outcomes in Patients with Peripheral Arterial Disease undergoing Lower Extremity Revascularization: A Systematic Review and Meta-Analysis. Journal Of Vascular Surgery 2025 PMID: 40015609, DOI: 10.1016/j.jvs.2025.02.018.Peer-Reviewed Original ResearchConceptsLower extremity revascularizationPeripheral arterial diseaseHospital readmissionRelative riskDiabetes mellitusRandom-effects meta-analysisIncreased riskMeta-analysisAssociation of DMExtremity revascularizationMortality riskWound infectionRisk estimatesAssociated with diabetes mellitusClinical outcomesSystematic reviewArtery diseaseSystematic searchObservational studyWound infection riskReadmissionEffects of diabetesAmputationRiskHospitalEffect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis—authors’ response
Hunter C, Marhoffer E, Holleck J, Alshaeba S, Grimshaw A, Chou A, Carey G, Gunderson C. Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis—authors’ response. Journal Of Antimicrobial Chemotherapy 2025, dkaf047. PMID: 39976564, DOI: 10.1093/jac/dkaf047.Peer-Reviewed Original ResearchUnderrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials
Ali T, Grimshaw A, Thomas A, Solomon M, Ross J, Miller P. Underrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials. European Heart Journal Acute Cardiovascular Care 2025, zuaf023. PMID: 39950988, DOI: 10.1093/ehjacc/zuaf023.Peer-Reviewed Original ResearchConceptsContemporary cardiac intensive care unitsRandomized controlled trialsIschemic heart diseaseCardiovascular diseaseHeart failureDisciplines of critical care medicineHistory of heart failureProspective randomized controlled trialsHeart diseaseControlled trialsExclusion criteriaMultivariate logistic regression analysisCardiac intensive care unitProportion of patientsExclusion of patientsComorbid cardiovascular diseaseCardiovascular disease historyIntensive care unitLogistic regression analysisApplication of randomized controlled trialsComplex patient populationGeneral internal medicineCardiovascular disease comorbiditiesMulticenter trialIndependent predictorsPractices and perspectives of genetic counselors about high‐risk pancreatic cancer screening: A cross‐sectional survey study
Wiegand A, Chhoda A, Namboodiri A, Grimshaw A, Dalela D, Farrell J. Practices and perspectives of genetic counselors about high‐risk pancreatic cancer screening: A cross‐sectional survey study. Journal Of Genetic Counseling 2025, 34: e2016. PMID: 39814542, DOI: 10.1002/jgc4.2016.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsCancer screening programHigher risk of pancreatic cancerPancreatic cancer screeningPancreatic cancer screening programsHigh-risk individualsGenetic counselorsCancer screeningScreening programReferral of high-risk individualsPerspectives of genetic counselorsCancer genetic counselorsCross-sectional survey studyIncrease provider comfortGenetic counseling programsIdentification of high-risk individualsPancreatic cancerConsensus guidelinesProvider comfortPancreas ScreeningExpert consensus guidelinesIdeal providersIdentification of individualsSurveillance of individualsCounseling individualsReferralEffectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis
Sannaa W, Almasry M, Peedikayil M, Grimshaw A, Attamimi M, AlMutairdi A, Al-Bawardy B. Effectiveness and safety of oral vancomycin for the treatment of inflammatory bowel disease associated with primary sclerosing cholangitis: a systematic review and pooled analysis. Therapeutic Advances In Gastroenterology 2025, 18: 17562848241312766. PMID: 39802627, PMCID: PMC11719443, DOI: 10.1177/17562848241312766.Peer-Reviewed Original ResearchConceptsOral vancomycin therapyPrimary sclerosing cholangitisIBD-PSCInflammatory bowel diseasePooled analysisClinical responseSclerosing cholangitisEpisodes of acute cholangitisFavorable side effect profilePooled analysis of studiesSystematic reviewInflammatory bowel disease associated with primary sclerosing cholangitisSide effect profileLong-term safetyClinical response/remissionVancomycin therapyOral vancomycinClinical remissionEndoscopic remissionAcute cholangitisMedian durationImmunosuppressive agentsNo episodesConcomitant treatmentEffect profile
2024
Efficacy of antiobesity medications for weight reduction in older adults: a systematic review
Chen A, Hajduk A, Grimshaw A, Fried T, Jastreboff A, Lipska K. Efficacy of antiobesity medications for weight reduction in older adults: a systematic review. Obesity 2024 PMID: 39725567, DOI: 10.1002/oby.24160.Peer-Reviewed Original ResearchConceptsOlder adultsAntiobesity medicationsStudy of older adultsOlder adults ageAdult ageCardiovascular diseaseRisk of biasAdverse events associated with useWeight reductionStatistically significant weight reductionFood and Drug AdministrationClinical careSystematic reviewInclusion criteriaLimited evidenceBaseline weightPlacebo groupObservational studySeven medicationsAdverse eventsAdultsDrug AdministrationEvaluation studiesMedicationSignificant weight reductionImpact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysis
Rassi A, Grimshaw A, Sarwal A, Sah R, Shah S, Agudelo Higuita N, Rassi F, Corbisiero M, Kyllo H, Stellern J, Kaplan S, Marcos L, Ramírez-García E, Casapia M, Hotez P, Bottazzi M, Patel S, Franco-Paredes C, Marin-Neto J, Henao-Martínez A. Impact of antiparasitic therapy on cardiovascular outcomes in chronic Chagas disease. A systematic review and meta-analysis. EClinicalMedicine 2024, 79: 102972. PMID: 39810938, PMCID: PMC11732499, DOI: 10.1016/j.eclinm.2024.102972.Peer-Reviewed Original ResearchConceptsChronic Chagas diseaseMethodological quality of studiesCardiovascular deathQuality of studiesDisease progressionQuality of evidenceVirtual Health Library databasesRisk of bias scaleCardiovascular outcomesRandom-effects modelPooled risk ratioMeta-analysis of studiesMethodological qualityWeb of Science Core CollectionAntitrypanosomal therapyRandomized controlled studyManagement of Chagas diseaseOvid MEDLINESystematic reviewInclusion criteriaMeta-analysesRisk ratioScience Core CollectionPrimary outcomeOvid EmbaseEffect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis
Hunter C, Marhoffer E, Holleck J, Alshaeba S, Grimshaw A, Chou A, Carey G, Gunderson C. Effect of empiric antibiotics against Pseudomonas aeruginosa on mortality in hospitalized patients: a systematic review and meta-analysis. Journal Of Antimicrobial Chemotherapy 2024, 80: 322-333. PMID: 39656468, DOI: 10.1093/jac/dkae422.Peer-Reviewed Original ResearchConceptsPrevalence of P. aeruginosaEffects of empiric antibioticsEmpirical antibioticsUrinary tract infectionSoft tissue infectionsCommunity-acquired pneumoniaTract infectionsTissue infectionsP. aeruginosaMortality benefitHospitalized patientsPseudomonas aeruginosaPooled adjusted ORP. aeruginosa infectionType of infectionStudy of patientsAbsolute mortality benefitIntensive care settingSystematic literature searchNosocomial pneumoniaSeptic shockMeaningful benefitAdjusted ORWeb of ScienceCompare mortality ratesReasons for declining participation in inpatient research among historically minoritized racial and ethnic communities: A scoping review
Bavishi P, Grimshaw A, Perez O, Kiluk B, Edelman E. Reasons for declining participation in inpatient research among historically minoritized racial and ethnic communities: A scoping review. Contemporary Clinical Trials Communications 2024, 42: 101386. PMID: 39659902, PMCID: PMC11629279, DOI: 10.1016/j.conctc.2024.101386.Peer-Reviewed Original ResearchConceptsStudy burdenInpatient hospital settingSocial support networksSocial support systemsPhysician involvementScoping reviewRecruitment methodsInpatient settingPatient trustWeb of Science databasesDeclined participationRefusing participationEquitable recruitmentEthnicity dataHospital settingSupport networksRecruitment effortsRefusal reasonsInpatient stayStudy designInclusion criteriaEnhance participationDemographic informationCochrane LibraryClinical trialsGlobal Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database.
Alhajahjeh A, Rotter L, Stempel J, Grimshaw A, Bewersdorf J, Blaha O, Kewan T, Podoltsev N, Shallis R, Mendez L, Stahl M, Zeidan A. Global Disparities in the Characteristics and Outcomes of Leukemia Clinical Trials: A Cross-Sectional Study of the ClinicalTrials.gov Database. JCO Global Oncology 2024, 10: e2400316. PMID: 39621951, DOI: 10.1200/go-24-00316.Peer-Reviewed Original ResearchMeSH Keywords and Concepts
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