Suchitra Krishnan-Sarin, PhD
Albert E. Kent Professor of PsychiatryCards
Appointments
Additional Titles
Chair, Human Investigations Committee (IRB), Human Research Protections Program
Professor, Chronic Disease Epidemiology
Contact Info
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States
Appointments
Additional Titles
Chair, Human Investigations Committee (IRB), Human Research Protections Program
Professor, Chronic Disease Epidemiology
Contact Info
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States
Appointments
Additional Titles
Chair, Human Investigations Committee (IRB), Human Research Protections Program
Professor, Chronic Disease Epidemiology
Contact Info
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States
About
Titles
Albert E. Kent Professor of Psychiatry
Chair, Human Investigations Committee (IRB), Human Research Protections Program; Professor, Chronic Disease Epidemiology
Biography
Dr. Suchitra Krishnan-Sarin is a Professor of Psychiatry at the Yale University School of Medicine. She is also a Chair of the Human Investigations Committee (IRB) at Yale. Her research is focused on developing a bio-behavioral understanding of substance use behaviors in adult and adolescent substance users, with the goal of developing optimal prevention and cessation interventions. In the area of adolescent tobacco use, her research focuses on understanding the appeal, abuse potential and patterns of use of tobacco products, developing and testing the use of novel behavioral and pharmacological cessation and prevention interventions, and understanding behavioral and neural predictors of use and cessation behaviors. She has contributed to the Surgeon General’s reports on youth tobacco use behaviors, served as a member of the FDA’s Tobacco Product Scientific Advisory Committee and currently serves on the CDC's Interagency Commission on Smoking and Health. Dr. Krishnan-Sarin is the Co-PI on the Yale Tobacco Centers Of Regulatory Science, funded by the NIH and FDA, which is using a multidisciplinary approach to understand the role of flavors and other constituents of tobacco products in tobacco and nicotine addiction. She also leads the ENACT initiative funded by the American Heart Association which is focused on developing interventions for e-cigarette use behaviors among youth. In a separate and distinct line of research Dr. Krishnan-Sarin also develops and tests novel pharmacological interventions for alcohol use disorders in adults and examines neurochemical predictors of alcohol use and treatment response.
Appointments
Psychiatry
ProfessorPrimaryChronic Disease Epidemiology
ProfessorSecondary
Other Departments & Organizations
- Cancer Prevention and Control
- Center for Nicotine and Tobacco Use Research at Yale (CENTURY)
- Center for the Translational Neuroscience of Alcohol
- Chronic Disease Epidemiology
- Connecticut Mental Health Center
- Division of Addictions
- Division of Women's Behavioral Health Research
- Neuroscience Research Training Program (NRTP)
- Psychiatry
- Psychology Section
- Psychotherapy Development Center
- Substance Abuse Research
- Yale Cancer Center
- Yale School of Public Health
- Yale Tobacco Center of Regulatory Science
- Yale Ventures
Education & Training
- Postdoctoral Fellow
- Yale Univeristy (1996)
- Postdoctoral fellowship
- Indiana University Purdue University at Indianapolis (1995)
- PhD
- Purdue University (1992)
Research
Overview
My research is focused on developing novel and effective treatments for substance use behaviors among youth and adults. Among youth, this work involves understanding the prevalence and bio-behavioral underpinnings of risk taking behaviors, using a developmental perspective, and behavioral and neuroimaging methods, and translating this information into optimal prevention and cessation intervention that use experimental, behavioral and pharmacological methods. While most of this work has focused on tobacco use behaviors, we have also extended these efforts to alcohol and marijuana use among youth. My research is also focused on developing empirical scientific evidence to support national and international tobacco regulatory efforts. Among adults, my work has focused using a translational approach to developing and evaluating medications to reduce alcohol drinking among heavy drinkers.
Medical Subject Headings (MeSH)
ORCID
0000-0002-3272-9782- View Lab Website
Tobacco Research in Youth
Research at a Glance
Yale Co-Authors
Research Interests
Grace Kong, PhD
Krysten Bold, PhD
Meghan Morean, PhD
Danielle Davis, PhD
Deepa Camenga, MD, MHS, FAAP
Eugenia Buta, PhD
Smoking Cessation
Nicotine
Publications
2024
Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues
Erythropel H, Jabba S, Silinski P, Anastas P, Krishnan-Sarin S, Zimmerman J, Jordt S. Variability in Constituents of E-Cigarette Products Containing Nicotine Analogues. JAMA 2024, 332 PMID: 39110443, PMCID: PMC11307159, DOI: 10.1001/jama.2024.12408.Peer-Reviewed Original ResearchCitationsAltmetricConceptsTime for a Focus on Cessation of E-Cigarettes
Krishnan-Sarin S, Fucito L. Time for a Focus on Cessation of E-Cigarettes. JAMA Internal Medicine 2024, 184: 930-931. PMID: 38709519, DOI: 10.1001/jamainternmed.2024.1310.Peer-Reviewed Original ResearchAltmetricUnintended exposure to e-liquids and subsequent health outcomes among US youth and adults
Lee J, Kong G, Krishnan-Sarin S, Camenga D. Unintended exposure to e-liquids and subsequent health outcomes among US youth and adults. PLOS ONE 2024, 19: e0308006. PMID: 39078829, PMCID: PMC11288430, DOI: 10.1371/journal.pone.0308006.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsOlder adultsE-liquid exposureYoung adultsUS youthAssociated with higher oddsE-cigarette useHealth outcomesHigher oddsAnalytic sampleWarning labelsWave 5E-cigarettesPopulation AssessmentPackaging regulationsAdultsHospitalYouthPrevalenceOutcomesSurvey dataE-liquidsDevice typeOddsHealthUnintended exposureW36 Cooling Flavors Use and E-Cigarette Nicotine Dependence Among Youth
Li W, Davis D, Bold K, Camenga D, Jackson A, Kong G, Lee J, Morean M, Sharma A, Krishnan-Sarin S. W36 Cooling Flavors Use and E-Cigarette Nicotine Dependence Among Youth. Drug And Alcohol Dependence 2024, 260: 110654. DOI: 10.1016/j.drugalcdep.2023.110654.Peer-Reviewed Original ResearchW126 Understanding Cannabis Use Among Teens who Vape Nicotine
Davis D, Wu R, Bold K, Kong G, Morean M, Krishnan-Sarin S. W126 Understanding Cannabis Use Among Teens who Vape Nicotine. Drug And Alcohol Dependence 2024, 260: 110744. DOI: 10.1016/j.drugalcdep.2023.110744.Peer-Reviewed Original ResearchDEVELOPING AN APP TO PROVIDE CBT FOR VAPING CESSATION TO YOUTH E-CIGARETTE USERS
Kong G, Krishnan-Sarin S, Gordon M, Frankforter T, Bold K. DEVELOPING AN APP TO PROVIDE CBT FOR VAPING CESSATION TO YOUTH E-CIGARETTE USERS. Drug And Alcohol Dependence 2024, 260: 110011. DOI: 10.1016/j.drugalcdep.2023.110011.Peer-Reviewed Original ResearchPsychometric evaluation of the Self-Report Habit Index for assessing habitual e-cigarette use behavior in high school adolescents
Morean M, Davis D, Kong G, Bold K, Talley A, Krishnan-Sarin S. Psychometric evaluation of the Self-Report Habit Index for assessing habitual e-cigarette use behavior in high school adolescents. Drug And Alcohol Dependence Reports 2024, 12: 100251. PMID: 39050698, PMCID: PMC11267024, DOI: 10.1016/j.dadr.2024.100251.Peer-Reviewed Original ResearchConceptsSelf-Report Habit IndexE-cigarette dependencePsychometric propertiesInternal reliabilityUse behaviorsE-cigarette use behaviorsE-cigarette useHabit IndexLatent factor structureSolid psychometric propertiesHigh school adolescentsE-cigarette flavorsFactor structureConnecticut high schoolsMeasurement invarianceBetween-group differencesHigh school studentsE-cigarettesHabitual behaviorPsychometric evaluationSelf-reportHabitual usePast-month e-cigarette useNicotine-freeVaping frequencySex differences in appeal, reward, and sensory experience of E-cigarette flavors among adults who smoke cigarettes
Davis D, Buta E, Green B, Krishnan-Sarin S. Sex differences in appeal, reward, and sensory experience of E-cigarette flavors among adults who smoke cigarettes. Preventive Medicine 2024, 185: 108040. PMID: 38866212, PMCID: PMC11323236, DOI: 10.1016/j.ypmed.2024.108040.Peer-Reviewed Original ResearchConceptsDrug Effects QuestionnaireE-cigarette appealLabeled Hedonic ScaleGeneral Labeled Magnitude ScaleSensory experienceEffects of sexSex differencesRewardEffective questionnairesExploratory analysisE-cigarette flavorsNicotine concentrationsE-cigarettesSmoking cigarettesE-cigarette experienceIntensity of flavorLinear mixed modelsMenthol flavorsEffects of e-cigarettesAdultsSexScaleHedonic scaleCigaretteCuesVarenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial
Fucito L, Baldassarri S, Baker N, Palmer A, O'Malley S, Carpenter M, Krishnan-Sarin S, Gray K, Toll B. Varenicline for E-Cigarette Cessation in Adults: A Preliminary Placebo-Controlled Randomized Trial. American Journal Of Preventive Medicine 2024, 67: 296-298. PMID: 38752949, PMCID: PMC11260542, DOI: 10.1016/j.amepre.2024.04.007.Peer-Reviewed Original ResearchAltmetricHow healthcare providers and the right information may play a critical role in quitting success among smokers interested in using e-cigarettes for quitting: Results from a survey of U.S adults
Sharma A, King J, Krishnan-Sarin S, O’Malley S, Morean M, Bold K. How healthcare providers and the right information may play a critical role in quitting success among smokers interested in using e-cigarettes for quitting: Results from a survey of U.S adults. PLOS ONE 2024, 19: e0303245. PMID: 38753868, PMCID: PMC11098412, DOI: 10.1371/journal.pone.0303245.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsHealthcare providersQuit smokingE-cigarettesBenefits of e-cigarettesPromote smoking cessationPotential public health benefitsGlobal public health priorityPublic health priorityReduce cigarette smokingIncrease quit ratesSmoking cessation attemptsCessation supportNicotine concentrationsHealth prioritySource of informationQuit ratesUS adultsU.S adultsSmoking cessationQuit successCessation attemptsHealthcareProvidersSmokingCigarette smoking
Clinical Trials
Current Trials
Varenicline for treatment of e-cigarette dependence
HIC ID2000032740RoleSub InvestigatorPrimary Completion Date09/30/2023Recruiting ParticipantsGenderBothAge18+ yearsAn fMRI study of responses to e-cigarette advertising and warnings among adolescents
HIC ID2000024730RoleSub InvestigatorPrimary Completion Date04/30/2024Recruiting ParticipantsGenderBothAge13 years - 19 yearsA longitudinal study of the effects of cannabis exposure on neuro-development in adolescents and young adults
HIC ID2000024543RoleSub InvestigatorPrimary Completion Date01/31/2021Recruiting ParticipantsGenderBothAge13 years - 25 yearsImaging smoking-induced dopamine release utilizing PET imaging and nicotine patches
HIC ID2000023239RoleSub InvestigatorPrimary Completion Date05/31/2023Recruiting ParticipantsGenderBothAge18 years - 55 years
Academic Achievements and Community Involvement
activity Addiction
Professional OrganizationsEditorDetailsJournal Editorial Board12/01/2015 - Presentactivity Surgeon General’s Report “Preventing Tobacco Use Among Young People”.
Public ServiceAuthorDetailsHealth effects of smoking on children, adolescents, and young adults2012 - Presentactivity Institute of Medicine of the National Academies Report “Scientific Standards for Studies on Modified Risk Tobacco Products
Public ServiceAuthorDetailsEthics and Oversight of Research Studies on Modified Risk Tobacco Products2012 - Presentactivity Society for Research on Nicotine and Tobacco
Professional OrganizationsPresidentDetails03/01/2020 - Presentactivity DHHS Interagency committee on Smoking and Health, Center for Disease Control and Prevention
Peer Review Groups and Grant Study SectionsAd-hoc MemberDetails12/01/2019 - Present
Links & Media
News
- August 07, 2024
Novel E-Cigarette Products Marketed to Contain Nicotine Analogs Instead of Nicotine Show Discrepancies Between Label Information and Contents
- August 07, 2024Source: CNN
How do teens quit vaping? Some simply send a text for help, new study shows | CNN
- July 10, 2024Source: The New York Times
How to Quit Vaping
- June 03, 2024Source: Scientific American
How Tobacco Companies Use Chemistry To Get Around Menthol Bans
Get In Touch
Contacts
Psychiatry
Connecticut Mental Health Center, 34 Park Street
New Haven, CT 06519
United States