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Miyoung Shin, PhD, MS, BS

Associate Research Scientist

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Associate Research Scientist

Biography

Miyoung Shin, PhD, is a Postdoctoral Associate at Yale School of Medicine and a member of the Huh Lab, which studies Ménétrier's disease, cell plasticity, and sex-differential expression of the epidermal growth factor receptor. Dr. Shin previously worked as a staff research associate at the UC San Diego Center for Epigenomics, where she was a key member of the Functional and Spatial Genomics team focused on cellular heterogeneity in human disease.

Dr. Shin earned her PhD in Molecular Biology from Korea University in Seoul, her MS in Biological Sciences from Seoul National University, and her BS in Molecular Biology from Dankook University. Her initial postdoctoral work at Yale has included preparing preliminary data and manuscripts for a research article in gastric cancer.

Her research interests are in spatial genomics and cancer biology and throughout her scientific career, she has published several peer-reviewed articles targeting and monitoring EGFR functioning in cancer cells. Dr. Shin’s academic training and research experiences have provided her with a unique background and skills in molecular biology and cancer research. With these experiences, her goal is to contribute to verifying the promising targets of advanced cancer progression at single-cell resolution.

Dr. Shin’s time at the UC San Diego Center for Epigenomics gave her the opportunity to discover the critical molecular mechanisms and chromatin changing involved in human diseases, such as type II diabetes and heart failure, to identify novel therapeutic targets using MERFISH (Multiplexed Error Robust Fluorescence in situ Hybridization) techniques. She contributed to the setup of single-molecule FISH experiments in the lab and optimizing the protocol for reproducible results in spatial genomics application.

Prior to San Diego, Dr. Shin was a Molecular Geneticist at the Center for Human Genetics at Clemson University, where she worked on development and setups for NGS approaches with NovaSeq6000 and minion and prepared the SOPs for NGS library generation and automation with Eppendorf epMotion. She also served as a Postdoctoral Associate at Sylvester Cancer Center, University of Miami, and as a Postdoctoral Associate at the College of Pharmacy, University of Florida.

Appointments

Other Departments & Organizations

Education & Training

PhD
Korea University, Molecular Biology (2014)
MS
Seoul National University, Biological Sciences (2002)
BS
Dankook University, Molecular Biology (2000)

Research

Overview

Postdoctoral Associate, Department of Pathology, Yale School of Medicine, CT, US (Present)

  • Preparing preliminary data and manuscripts for research article in gastric cancer.
  • Development of new NGS sequencing approaches including STARR-seq and MERFISH.
  • Provide various services for RNA-seq. and single cell RNA-sequencing.
  • Development and setups for NGS approaches with NovaSeq6000 and minION.
  • Preparing the SOPs for NGS library generation and automation with Eppendorf epMotion.
  • Investigating p27-regulated transcriptional mechanism in metastatic breast cancer.
  • Library preparation and analysis for mRNA/ChIP-sequencing with cancer cells and tissues.
  • Investigating the role of SWI/SNF nucleosome remodeling complex in Acute Myeloid Leukemia.
  • Identification of drug resistance gene features in CD33 targeted treatment cohort.

Staff Research Associate, Center for Epigenomics, UC San Diego, CA, US (2019 - 2021)

Molecular Geneticist, Center for Human Genetics, Clemson University, SC, US (2018 - 2019)

Postdoctoral Associate, Sylvester Cancer Center, University of Miami, FL, US (2016 - 2018)

Postdoctoral Associate, College of Pharmacy, University of Florida, FL, US (2015 - 2016)

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