Jesse Rinehart, PhD

Dr. Jesse Rinehart is an Associate Professor in the Department of Cellular & Molecular Physiology at the Yale University School of Medicine with a joint appointment in the Systems Biology Institute. Dr. Rinehart’s research aims to understand and “decode” the roles of protein phosphorylation in humans. His laboratory uses an innovative combination of quantitative phosphoproteomics and synthetic biology study protein phosphorylation in single proteins and protein networks. Recently, research in Dr. Rinehart’s laboratory has been accelerated by their Escherichia coli based technology that enables site-specific incorporation of phosphoserine into human proteins. Dr. Rinehart received his PhD in Molecular Biophysics and Biochemistry from Yale in 2005. He studied protein synthesis and the evolution of the genetic code during his graduate work with Dr. Dieter Söll. His did his postdoctoral research with Richard Lifton in the Department of Genetics at the Yale University School of Medicine and focused on understanding the role of protein phosphorylation in physiological systems.