Yun-Hee Youm
Associate Research Scientist in PathologyCards
About
Research
Publications
2010
Obesity increases the production of pro-inflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin-resistance (87.32)
Youm Y, Yang H, Badanmagsar B, Gimble J, Greenway F, Mynatt R. Obesity increases the production of pro-inflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin-resistance (87.32). The Journal Of Immunology 2010, 184: 87.32-87.32. DOI: 10.4049/jimmunol.184.supp.87.32.Peer-Reviewed Original ResearchT cellsVisceral fatTCR repertoireTCR diversityAdipose depotsAdipose tissueAdipose tissue T cellsSpecific adipose depotsTCR Vβ repertoireUnique TCR repertoireEffector memory cellsObesity-associated inflammationPro-inflammatory mediatorsActivated T cell populationsPro-inflammatory cytokinesTissue T cellsT cell populationsTCR repertoire diversityProinflammatory microenvironmentSystemic inflammationObesity altersObese miceT lymphocytesObesityRepertoire diversity
2008
Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells
Youm YH, Kim S, Bahk YY, Yoo TK. Proteomic analysis of androgen-independent growth in low and high passage human LNCaP prostatic adenocarcinoma cells. BMB Reports 2008, 41: 722-727. PMID: 18959819, DOI: 10.5483/bmbrep.2008.41.10.722.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAndrogensCell ExtractsCell Line, TumorCell ProliferationClone CellsDoxazosinElectrophoresis, Gel, Two-DimensionalGene Expression Regulation, NeoplasticGene SilencingHumansMaleNeoplasm ProteinsProstatic NeoplasmsProteomeProteomicsReceptors, AndrogenRNA, MessengerRNA, Small InterferingConceptsAndrogen-independent growthAndrogen-independent phenotypeProstatic adenocarcinoma cellsAndrogen receptorLNCaP cellsLow passage numberReceptor productionAdenocarcinoma cellsCell clonesProtein expressionExpression levelsPassage numberPresent studyCellsProteomic characteristicsProteomic analysisAndrogensExpressionProgression
2007
Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells
Youm YH, Yang H, Yoon YD, Kim DY, Lee C, Yoo TK. Doxazosin-induced clusterin expression and apoptosis in prostate cancer cells. Urologic Oncology Seminars And Original Investigations 2007, 25: 483-488. PMID: 18047956, DOI: 10.1016/j.urolonc.2007.02.010.Peer-Reviewed Original ResearchConceptsProstate cancer cellsAndrogen-independent human prostate cancer cellsCancer cellsHuman prostate cancer cellsTranscriptase-polymerase chain reactionNick-end labeling assayMicroM doxazosinDegree of apoptosisDNA fragmentationDoxazosin treatmentClusterin mRNA expressionPolymerase chain reactionDoxazosin-induced apoptosisClusterin expressionMRNA expressionPC3 cellsPresence of clusterinClusterin mRNAChain reactionClusterinApoptotic cellsLabeling assaysDoxazosinApoptosisMP-17.13: Silencing of clusterin gene with siRNA accelerates doxazosin induced apoptosis in PC-3 human prostate cancer cell lines
Cha G, Yoo T, Youm Y, Jo M, Lee C. MP-17.13: Silencing of clusterin gene with siRNA accelerates doxazosin induced apoptosis in PC-3 human prostate cancer cell lines. Urology 2007, 70: 133-134. DOI: 10.1016/j.urology.2007.06.500.Peer-Reviewed Original Research
2006
MP-08.15 Prolonged culture of LNCaP prostate cancer cells leads to androgen independence and resistance to doxazosin induced apoptosis with clusterin up-regulation
Yoo T, Youm Y, Park H, Kang J, Park J, Kim T. MP-08.15 Prolonged culture of LNCaP prostate cancer cells leads to androgen independence and resistance to doxazosin induced apoptosis with clusterin up-regulation. Urology 2006, 68: 100-101. DOI: 10.1016/j.urology.2006.08.322.Peer-Reviewed Original ResearchMP-21.19 The effects of URO-Dr® treatment and finasteride on the apoptosis of prostate in beagle dogs
Yoo T, Cho H, Youm Y, Park J, Kim T, Kim H. MP-21.19 The effects of URO-Dr® treatment and finasteride on the apoptosis of prostate in beagle dogs. Urology 2006, 68: 194. DOI: 10.1016/j.urology.2006.08.620.Peer-Reviewed Original ResearchApoptosis Induction and Clusterin Expression of NRP-152 Cells by Tamsulosin
Youm Y, Yoon Y, Woo J, Yoo T. Apoptosis Induction and Clusterin Expression of NRP-152 Cells by Tamsulosin. Journal Of The Korean Continence Society 2006, 10: 132. DOI: 10.5213/jkcs.2006.10.2.132.Peer-Reviewed Original Research
2005
Less Keratinocyte-Derived Factors Related to More Keratinocyte Apoptosis in Depigmented than Normally Pigmented Suction-Blistered Epidermis May Cause Passive Melanocyte Death in Vitiligo
Lee AY, Kim NH, Choi WI, Youm YH. Less Keratinocyte-Derived Factors Related to More Keratinocyte Apoptosis in Depigmented than Normally Pigmented Suction-Blistered Epidermis May Cause Passive Melanocyte Death in Vitiligo. Journal Of Investigative Dermatology 2005, 124: 976-983. PMID: 15854039, DOI: 10.1111/j.0022-202x.2005.23667.x.Peer-Reviewed Original Research407: Clusterin Expression and Apoptosis Induction by Doxazosin in Human Prostate Cancer Cells
Yoo T, Youm Y, Cho J, Kang J, Yang H, Kim D. 407: Clusterin Expression and Apoptosis Induction by Doxazosin in Human Prostate Cancer Cells. Journal Of Urology 2005, 173: 111. DOI: 10.1016/s0022-5347(18)34660-3.Peer-Reviewed Original Research
2004
Keratinocytes in the depigmented epidermis of vitiligo are more vulnerable to trauma (suction) than keratinocytes in the normally pigmented epidermis, resulting in their apoptosis
Lee A, Youm Y, Kim N, Yang H, Choi W. Keratinocytes in the depigmented epidermis of vitiligo are more vulnerable to trauma (suction) than keratinocytes in the normally pigmented epidermis, resulting in their apoptosis. British Journal Of Dermatology 2004, 151: 995-1003. PMID: 15541077, DOI: 10.1111/j.1365-2133.2004.06136.x.Peer-Reviewed Original ResearchAdolescentAdultApoptosisBcl-2-Associated X ProteinCASP8 and FADD-Like Apoptosis Regulating ProteinCaspasesChildEpidermisFemaleHumansIntracellular Signaling Peptides and ProteinsKeratinocytesMaleMiddle AgedPoly(ADP-ribose) PolymerasesProto-Oncogene Proteins c-bcl-2SuctionTumor Suppressor Protein p53Vitiligo
News
News
- September 27, 2017
Battling belly fat: Specialized immune cells impair metabolism in aging
- January 10, 2016
Life-extending hormone bolsters the body’s immune function
- February 15, 2015
Anti-inflammatory mechanism of dieting and fasting revealed
- October 22, 2013
Controlling the triggers of age-related inflammation could extend ‘healthspan’